Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin
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2020
Authors
Petković, B.B.Ognjanović, M.
Krstić, Milena
Stanković, V.
Babincev, L.
Pergal, M.
Stanković, D.M.
Article (Published version)
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Mefenamic acid and indomethacin, medicaments belonging to the group of non-steroidal anti-inflammatory agents, were determined separately and simultaneously at anodically prepared BDDE. Differential pulse voltammetry was used to establish simple and fast analytical procedure based on electrooxidation of mefenamic acid at 0.6 V and indomethacin at 1.0 V (and 1.1 V). At optimal conditions, it was suitable for highly sensitive and selective determination of these compounds with LODs comparable to previously reported modified electrodes. Additionally, considering the importance of these compounds, we proposed precise and accurate quantification of these species based on green and simple pre-treatable electrochemical sensor. The effect of interfering agents (tablet ingredients and vitamins) was appeared to be negligibly confirming a favourable selectivity of the method. The proposed method was analytically applied by simultaneously determining mefenamic acid and indomethacin in pharmaceutic...al formulations.
Keywords:
Anti-inflammatory drug analysis / Indomethacin / Mefenamic acid / Unmodified BDDESource:
Diamond and Related Materials, 2020, 105, 107785-Publisher:
- Elsevier Ltd
Funding / projects:
- Financial support for this study was granted by the Ministry of Education, Science and Technological Development of the Republic of Serbia , Project Numbers III45022 , OI172030 and III45015 . DMS wish to acknowledge to the E! 13303 MED-BIO-TEST.
DOI: 10.1016/j.diamond.2020.107785
ISSN: 0925-9635
WoS: 000540291200018
Scopus: 2-s2.0-85081033676
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Fakultet veterinarske medicineTY - JOUR AU - Petković, B.B. AU - Ognjanović, M. AU - Krstić, Milena AU - Stanković, V. AU - Babincev, L. AU - Pergal, M. AU - Stanković, D.M. PY - 2020 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1813 AB - Mefenamic acid and indomethacin, medicaments belonging to the group of non-steroidal anti-inflammatory agents, were determined separately and simultaneously at anodically prepared BDDE. Differential pulse voltammetry was used to establish simple and fast analytical procedure based on electrooxidation of mefenamic acid at 0.6 V and indomethacin at 1.0 V (and 1.1 V). At optimal conditions, it was suitable for highly sensitive and selective determination of these compounds with LODs comparable to previously reported modified electrodes. Additionally, considering the importance of these compounds, we proposed precise and accurate quantification of these species based on green and simple pre-treatable electrochemical sensor. The effect of interfering agents (tablet ingredients and vitamins) was appeared to be negligibly confirming a favourable selectivity of the method. The proposed method was analytically applied by simultaneously determining mefenamic acid and indomethacin in pharmaceutical formulations. PB - Elsevier Ltd T2 - Diamond and Related Materials T1 - Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin VL - 105 SP - 107785 DO - 10.1016/j.diamond.2020.107785 ER -
@article{ author = "Petković, B.B. and Ognjanović, M. and Krstić, Milena and Stanković, V. and Babincev, L. and Pergal, M. and Stanković, D.M.", year = "2020", abstract = "Mefenamic acid and indomethacin, medicaments belonging to the group of non-steroidal anti-inflammatory agents, were determined separately and simultaneously at anodically prepared BDDE. Differential pulse voltammetry was used to establish simple and fast analytical procedure based on electrooxidation of mefenamic acid at 0.6 V and indomethacin at 1.0 V (and 1.1 V). At optimal conditions, it was suitable for highly sensitive and selective determination of these compounds with LODs comparable to previously reported modified electrodes. Additionally, considering the importance of these compounds, we proposed precise and accurate quantification of these species based on green and simple pre-treatable electrochemical sensor. The effect of interfering agents (tablet ingredients and vitamins) was appeared to be negligibly confirming a favourable selectivity of the method. The proposed method was analytically applied by simultaneously determining mefenamic acid and indomethacin in pharmaceutical formulations.", publisher = "Elsevier Ltd", journal = "Diamond and Related Materials", title = "Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin", volume = "105", pages = "107785", doi = "10.1016/j.diamond.2020.107785" }
Petković, B.B., Ognjanović, M., Krstić, M., Stanković, V., Babincev, L., Pergal, M.,& Stanković, D.M.. (2020). Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin. in Diamond and Related Materials Elsevier Ltd., 105, 107785. https://doi.org/10.1016/j.diamond.2020.107785
Petković B, Ognjanović M, Krstić M, Stanković V, Babincev L, Pergal M, Stanković D. Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin. in Diamond and Related Materials. 2020;105:107785. doi:10.1016/j.diamond.2020.107785 .
Petković, B.B., Ognjanović, M., Krstić, Milena, Stanković, V., Babincev, L., Pergal, M., Stanković, D.M., "Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin" in Diamond and Related Materials, 105 (2020):107785, https://doi.org/10.1016/j.diamond.2020.107785 . .