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dc.creatorLoncarić, Igor
dc.creatorKuebber-Heiss, Anna
dc.creatorPosautz, Annika
dc.creatorRuppitsch, Werner
dc.creatorLepuschitz, Sarah
dc.creatorSchauer, Bernhard
dc.creatorFessler, Andrea T.
dc.creatorKrametter-Froetscher, Reinhild
dc.creatorHarrison, Ewan M.
dc.creatorHolmes, Mark A.
dc.creatorKuenzel, Frank
dc.creatorSzostak, Michael
dc.creatorHauschild, Tomasz
dc.creatorDesvars-Larrive, Amelie
dc.creatorMišić, Dušan
dc.creatorRosengarten, Renate
dc.creatorWalzer, Chris
dc.creatorSlickers, Peter
dc.creatorMonecke, Stefan
dc.creatorEhricht, Ralf
dc.creatorSchwarz, Stefan
dc.creatorSpergser, Joachim
dc.date.accessioned2020-06-18T22:18:56Z
dc.date.available2020-02-05
dc.date.issued2019
dc.identifier.issn0378-1135
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/1845
dc.description.abstractThe presence of the methicillin resistance gene mecC in coagulase-negative Staphylococcus spp. (CoNS) is scarce. The aim of this study was to characterize mecC-positive CoNS isolated from various wild and domestic animals. The presence of the mecC gene was screened in 4299 samples from wild animals and domestic animals. Fifteen coagulase-negative staphylococci, that displayed a cefoxitin-resistant phenotype, were tested mecC-positive by PCR. Antimicrobial susceptibility testing was performed for all isolates. The 15 isolates were genotyped by sequencing of the entire class E mec gene complex (blaZ-mecC-mecRI-mecI), the ccrA and ccrB recombinase genes and other determinants within the type XI SCCmec element. DNA microarray analysis was performed and five selected isolates were additionally whole genome sequenced and analyzed. S. stepanovicii (n = 3), S. caprae (n = 1), S. warneri (n = 1), S. xylosus (n = 1) and S. sciuri (n = 9) were detected. All but the S. sciuri isolates were found to be susceptible to all non-beta lactams. The entire class E mec gene complex was detected in all isolates but ccrA and ccrB genes were not identified in S. stepanovicii and S. xylosus. The genes erm(B) and fexA (n = 4, each) were the most predominant non-beta lactam resistance genes detected in the S. sciuri isolates. Even though the presence of the mecC gene among CoNS is a rare observation, this study further expands our knowledge by showing that the mecC gene, including its allotypes, are present in more staphylococcal species from different animal species than has been previously described.en
dc.publisherElsevier, Amsterdam
dc.relationResearch Institute of Wildlife Ecology from University of Veterinary Medicine Vienna, Austria
dc.relationAustrian Buiatric association
dc.relationFederal Ministry of Education and Research (BMBF) as part of the Research Network Zoonotic Infectious DiseasesFederal Ministry of Education & Research (BMBF) [01KI1727D]
dc.rightsembargoedAccess
dc.sourceVeterinary Microbiology
dc.subjectmecAen
dc.subjectmecCen
dc.subjectCoagulase-negative Staphylococcus spp.en
dc.subjectAnimalsen
dc.subjectAntimicrobial resistanceen
dc.titleCharacterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animalsen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractЛонцарић, Игор; Сзостак, Мицхаел; Хаусцхилд, Томасз; Десварс-Ларриве, Aмелие; Спергсер, Јоацхим; Куеббер-Хеисс, Aнна; Посаутз, Aнника; Руппитсцх, Wернер; Лепусцхитз, Сарах; Сцхауер, Бернхард; Фесслер, Aндреа Т.; Краметтер-Фроетсцхер, Реинхилд; Харрисон, Еwан М.; Холмес, Марк A.; Куензел, Франк; Мишић, Душан; Росенгартен, Ренате; Wалзер, Цхрис; Слицкерс, Петер; Монецке, Стефан; Ехрицхт, Ралф; Сцхwарз, Стефан;
dc.citation.volume230
dc.citation.spage138
dc.citation.epage144
dc.citation.other230: 138-144
dc.citation.rankaM21
dc.description.otherThis is the peer-reviewed version of the article: Loncarić, I.; Kuebber-Heiss, A.; Posautz, A.; Ruppitsch, W.; Lepuschitz, S.; Schauer, B.; Fessler, A. T.; Krametter-Froetscher, R.; Harrison, E. M.; Holmes, M. A.; Kuenzel, F.; Szostak, M.; Hauschild, T.; Desvars-Larrive, A.; Mišić, D.; Rosengarten, R.; Walzer, C.; Slickers, P.; Monecke, S.; Ehricht, R.; Schwarz, S.; Spergser, J. Characterization of MecC Gene-Carrying Coagulase-Negative Staphylococcus Spp. Isolated from Various Animals. Veterinary Microbiology 2019, 230, 138–144. [https://doi.org/10.1016/j.vetmic.2019.02.014]
dc.identifier.wos000461534600020
dc.identifier.doi10.1016/j.vetmic.2019.02.014
dc.identifier.pmid30827379
dc.identifier.scopus2-s2.0-85061198671
dc.identifier.fulltexthttp://veterinar.vet.bg.ac.rs/bitstream/id/4854/Characterization_of_mecC_acc_2019.pdf
dc.type.versionacceptedVersion


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