Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus
Autori
Žižović, IrenaSenerović, Lidija
Morić, Ivana
Adamović, Tijana
Jovanović, Milena
Krušić, Melina Kalagasidis
Mišić, Dušan
Stojanović, Dušica
Milovanović, Stoja
Članak u časopisu (Recenzirana verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
This study discusses utilization of supercritical carbon dioxide for impregnation of cellulose acetate films with thymol in order to produce material with anti-biofilm activity against Pseudomonas aeruginosa and Staphylococcus aureus. Analysis of anti-biofilm activity of cellulose acetate beads impregnated with thymol suggested that optimal thymol loading was in the range from 26% to 30% for efficient reduction of biofilm formation and eradication of pre-formed biofilms. Polymer films were fabricated by the solvent casting method from polymer solutions of different contents, and loaded with thymol using supercritical carbon dioxide at 15.5 MPa and 35 °C. The film containing 30% of thymol (F1 30%) exhibited substantial anti-adhesion properties inhibiting biofilm formation on its surface and considerably reduced formation of biofilms on the surrounding surfaces (up to 80%) by all tested strains including antibiotic resistant P. aeruginosa DM50 and methicillin-resistant S. aureus.
Ključne reči:
Cellulose acetate / Supercritical carbon dioxide impregnation / ThymolIzvor:
The Journal of Supercritical Fluids, 2018, 140, 11-20Izdavač:
- Elsevier
Finansiranje / projekti:
- Funkcionalni fiziološki aktivni biljni materijali sa dodatom vrednošću za primenu u farmaceutskoj i prehrambenoj industriji (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45017)
- Izučavanje mikrobiološkog diverziteta i karakterizacija korisnih sredinskih mikroorganizama (RS-MESTD-Basic Research (BR or ON)-173048)
Napomena:
- This is the peer-reviewed version of the article: Zizovic, I.; Senerovic, L.; Moric, I.; Adamovic, T.; Jovanovic, M.; Krusic, M. K.; Misic, D.; Stojanovic, D.; Milovanovic, S. Utilization of Supercritical Carbon Dioxide in Fabrication of Cellulose Acetate Films with Anti-Biofilm Effects against Pseudomonas Aeruginosa and Staphylococcus Aureus. The Journal of Supercritical Fluids 2018, 140, 11–20. https://doi.org/10.1016/j.supflu.2018.05.025
DOI: 10.1016/j.supflu.2018.05.025
ISSN: 0896-8446
WoS: 000446284200002
Scopus: 2-s2.0-85048565455
Kolekcije
Institucija/grupa
Fakultet veterinarske medicineTY - JOUR AU - Žižović, Irena AU - Senerović, Lidija AU - Morić, Ivana AU - Adamović, Tijana AU - Jovanović, Milena AU - Krušić, Melina Kalagasidis AU - Mišić, Dušan AU - Stojanović, Dušica AU - Milovanović, Stoja PY - 2018 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1847 AB - This study discusses utilization of supercritical carbon dioxide for impregnation of cellulose acetate films with thymol in order to produce material with anti-biofilm activity against Pseudomonas aeruginosa and Staphylococcus aureus. Analysis of anti-biofilm activity of cellulose acetate beads impregnated with thymol suggested that optimal thymol loading was in the range from 26% to 30% for efficient reduction of biofilm formation and eradication of pre-formed biofilms. Polymer films were fabricated by the solvent casting method from polymer solutions of different contents, and loaded with thymol using supercritical carbon dioxide at 15.5 MPa and 35 °C. The film containing 30% of thymol (F1 30%) exhibited substantial anti-adhesion properties inhibiting biofilm formation on its surface and considerably reduced formation of biofilms on the surrounding surfaces (up to 80%) by all tested strains including antibiotic resistant P. aeruginosa DM50 and methicillin-resistant S. aureus. PB - Elsevier T2 - The Journal of Supercritical Fluids T1 - Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus VL - 140 SP - 11 EP - 20 DO - 10.1016/j.supflu.2018.05.025 ER -
@article{ author = "Žižović, Irena and Senerović, Lidija and Morić, Ivana and Adamović, Tijana and Jovanović, Milena and Krušić, Melina Kalagasidis and Mišić, Dušan and Stojanović, Dušica and Milovanović, Stoja", year = "2018", abstract = "This study discusses utilization of supercritical carbon dioxide for impregnation of cellulose acetate films with thymol in order to produce material with anti-biofilm activity against Pseudomonas aeruginosa and Staphylococcus aureus. Analysis of anti-biofilm activity of cellulose acetate beads impregnated with thymol suggested that optimal thymol loading was in the range from 26% to 30% for efficient reduction of biofilm formation and eradication of pre-formed biofilms. Polymer films were fabricated by the solvent casting method from polymer solutions of different contents, and loaded with thymol using supercritical carbon dioxide at 15.5 MPa and 35 °C. The film containing 30% of thymol (F1 30%) exhibited substantial anti-adhesion properties inhibiting biofilm formation on its surface and considerably reduced formation of biofilms on the surrounding surfaces (up to 80%) by all tested strains including antibiotic resistant P. aeruginosa DM50 and methicillin-resistant S. aureus.", publisher = "Elsevier", journal = "The Journal of Supercritical Fluids", title = "Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus", volume = "140", pages = "11-20", doi = "10.1016/j.supflu.2018.05.025" }
Žižović, I., Senerović, L., Morić, I., Adamović, T., Jovanović, M., Krušić, M. K., Mišić, D., Stojanović, D.,& Milovanović, S.. (2018). Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus. in The Journal of Supercritical Fluids Elsevier., 140, 11-20. https://doi.org/10.1016/j.supflu.2018.05.025
Žižović I, Senerović L, Morić I, Adamović T, Jovanović M, Krušić MK, Mišić D, Stojanović D, Milovanović S. Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus. in The Journal of Supercritical Fluids. 2018;140:11-20. doi:10.1016/j.supflu.2018.05.025 .
Žižović, Irena, Senerović, Lidija, Morić, Ivana, Adamović, Tijana, Jovanović, Milena, Krušić, Melina Kalagasidis, Mišić, Dušan, Stojanović, Dušica, Milovanović, Stoja, "Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus" in The Journal of Supercritical Fluids, 140 (2018):11-20, https://doi.org/10.1016/j.supflu.2018.05.025 . .