Protection of chickens with maternally derived antibodies after challenge with very virulent infectious bursal disease virus

Abstract

The protective value of maternally derived antibodies in broiler breeders and broilers was tested after challenge with very virulent infectious bursal disease virus. Chickens were infected on the 14th and 10th day of age respectively. According to the pathohistological lesions in the bursa of Fabricius protection was poor, namely 21.4% in both experiments. The primary antibody response after challenge measured by virus neutralization test (VN) was correlated with the extensive pathohistological lesions in the bursa of infected chickens.

U ovom radu su izneti rezultati ispitivanja zaštitne vrednosti maternalnih antitela kod brojlerskih roditelja i brojlerskih pilića posle infekcije vrlo virulentnim virusom infektivnog oboljenja burze. Pilići su inficirani 14. i 10. dana života a na osnovu patohistoloških lezija u burzi Fabricii zaključeno je daje zaštita pilića bila slaba (21,4% u oba eksperimenta). Primami imunološki odgovor posle infekcije, ustanovljen virus neutralizacionim testom, je bio u visokoj korelaciji sa patohistološkim lezijama ustanovljenim u burzama inficiranih pilića.