Zastupljenost i tipovi tumora mlečne žlezde kod kuja u biopsijskom materijalu

Abstract

Mlečna žlezda kuja je podložna neoplastičnim i neneoplastičnim patološkim promenama. Neoplazije ili tumori mlečne žlezde (TMŽ) predstavljaju najučestalije tumore kuja i samim tim važan problem u veterinarskoj medicini. Retrospektivnom studijom su obuhvaćene sve patološke alteracije u uzorcima mlečne žlezde pasa koje su dijagnostikovane u razdoblju od 1. januara 2008. godine do 15. novembra 2012. godine u laboratoriji Katedre za patologiju Fakulteta veterinarske medicine u Beogradu. Tkivni uzorci predstavljaju biopsijski materijal mlečne žlezde pasa koji je histopatološki analiziran. Istražen je uticaj starosti i rase na pojavljivanje patoloških promena na mlečnoj žlezdi pasa. Analizirano je i klasifikovano 258 patoloških promena mlečne žlezde pasa. Kod ženki je dijagnostikovano 257 (99,7%), a kod mužjaka jedna (0,3%) promena na mlečnoj žlezdi. Hiperplazija i displazija mlečne žlezde, kao i duktalna ektazija predstavljaju jedine neneoplastične promene utvrđene u retrospektivnoj analizi sa prevalencom od 3,90%. Prosečna starost 257 kuja sa patološkim promena na mlečnoj žlezdi iznosila je 9,53 ± 2,79 godine sa opsegom od 1 do 17 godina. Patološke promene su dijagnostikovane kod 32 rase kuja. Najčešća maligna alteracija je bila prosti karcinom (49,8%), dok je benigni mešoviti tumor bio najzastupljenija benigna neoplazma (5,2%). Najučestalije rase sa TMŽ bile su mešanci, terijeri i španijeli, dok je prosek godina obolelih kuja iznosio 9,53 godine i nije se značajno menjao u zavisnosti od tipa promene.

Mammary gland of bitches is susceptible to neoplastic and nonneoplastic pathological changes. Neoplasia or tumors of the mammary gland (TMG ) are the most common tumors in female dogs and therefore an important issue in veterinary medicine. The retrospective study included all pathological alterations that were diagnosed between 1. January 2008 and 15 November 2012 in the the laboratory in the Department of Pathology, Faculty of Veterinary Medicine in Belgrade. Tissue samples are biopsy material of mammary gland, which was histopathologically analyzed. We studied the effect of age and race on the incidence of pathological changes on the mammary gland. During a investigation period we analyzed and classified 258 pathological changes of mammary gland in dogs. In the females were diagnosed 257 (99.70%), and in males one (0.30%) alteration of mammary gland. Hyperplasia / dysplasia and mammary ductal ectasia are the only nonneoplastic changes that were found in a retrospective analysis with prevalence 3,90%. The average age of the 257 bitches with pathological changes on the mammary gland was 9.53 ± 2.79 years, with a range from 1 to 17 years. Pathological changes were diagnosed in the 32 races. The most common malignant transformation was simple carcinoma (49.80%), while the benign mixed tumor was the most common benign neoplastic change (5,20%). The most prevalent breed with TMG were crossbreed, terriers and spaniels, while the average age of patients was 9.53 years and did not change significantly depending on the type of change.