Cow milk insulin like growth factor-1: risk or benefit for human health?
2021
Аутори
Kirovski, DanijelaKnežević, Dragan
Golić, Bojan
Kasagić, Dragan
Jovanović, Ljubomir
Bošnjaković, Dušan
Trifković, Julijana
Sladojević, Željko
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Cow milk is widely consumed by human children and adults due to its nutritional value. Besides
nutrients, milk contains naturally occurring hormones, including insulin like growth factor-1
(IGF-1), that may alter their blood levels in the consumers. At the same time, the impact of IGF1 on human health is still unclear and controversial. The aim of the study was to determine IGF-1
concentrations in cow colostrum and milk and to discuss them from the aspect of human health.
Twenty Holstein cows were enrolled in the study and subjected to colostrum, milk and venous
blood sampling in order to determine the IGF-1 concentration by the radioimmunoassay (RIA).
Colostrum was sampled at 2, 14 and 26 hours (1st, 2nd and 3rd colostrum) after calving, while
milk and venous blood were taken 10 days after calving. The concentration of IGF-1 was the
highest in the 1
st colostrum and decreased significantly with each subsequent sampling, so the
lowest concentrations were detected in milk samp...led 10 days after calving. High concentrations
of IGF-1 observed in colostrum, especially in the 1st colostrum, reflect its potential for eventually
use in the treatment of various intestinal diseases. However, further research should determine
the conditions and limitations of its application. On the other hand, additional research is needed
to determine whether IGF-1 in milk has harmful effects on human health and whether it is
necessary to limit the permitted presence of this hormone in cow milk.
Кључне речи:
cow milk / insulin like growth factor-1 (IGF-1) / human healthИзвор:
Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“, 2021, 1196-1203Издавач:
- Faculty of Agriculture, Republic of Srpska, Bosnia
Финансирање / пројекти:
- 19.032/961-71/19
Колекције
Институција/група
Fakultet veterinarske medicineTY - CONF AU - Kirovski, Danijela AU - Knežević, Dragan AU - Golić, Bojan AU - Kasagić, Dragan AU - Jovanović, Ljubomir AU - Bošnjaković, Dušan AU - Trifković, Julijana AU - Sladojević, Željko PY - 2021 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2274 AB - Cow milk is widely consumed by human children and adults due to its nutritional value. Besides nutrients, milk contains naturally occurring hormones, including insulin like growth factor-1 (IGF-1), that may alter their blood levels in the consumers. At the same time, the impact of IGF1 on human health is still unclear and controversial. The aim of the study was to determine IGF-1 concentrations in cow colostrum and milk and to discuss them from the aspect of human health. Twenty Holstein cows were enrolled in the study and subjected to colostrum, milk and venous blood sampling in order to determine the IGF-1 concentration by the radioimmunoassay (RIA). Colostrum was sampled at 2, 14 and 26 hours (1st, 2nd and 3rd colostrum) after calving, while milk and venous blood were taken 10 days after calving. The concentration of IGF-1 was the highest in the 1 st colostrum and decreased significantly with each subsequent sampling, so the lowest concentrations were detected in milk sampled 10 days after calving. High concentrations of IGF-1 observed in colostrum, especially in the 1st colostrum, reflect its potential for eventually use in the treatment of various intestinal diseases. However, further research should determine the conditions and limitations of its application. On the other hand, additional research is needed to determine whether IGF-1 in milk has harmful effects on human health and whether it is necessary to limit the permitted presence of this hormone in cow milk. PB - Faculty of Agriculture, Republic of Srpska, Bosnia C3 - Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“ T1 - Cow milk insulin like growth factor-1: risk or benefit for human health? SP - 1196 EP - 1203 UR - https://hdl.handle.net/21.15107/rcub_veterinar_2274 ER -
@conference{ author = "Kirovski, Danijela and Knežević, Dragan and Golić, Bojan and Kasagić, Dragan and Jovanović, Ljubomir and Bošnjaković, Dušan and Trifković, Julijana and Sladojević, Željko", year = "2021", abstract = "Cow milk is widely consumed by human children and adults due to its nutritional value. Besides nutrients, milk contains naturally occurring hormones, including insulin like growth factor-1 (IGF-1), that may alter their blood levels in the consumers. At the same time, the impact of IGF1 on human health is still unclear and controversial. The aim of the study was to determine IGF-1 concentrations in cow colostrum and milk and to discuss them from the aspect of human health. Twenty Holstein cows were enrolled in the study and subjected to colostrum, milk and venous blood sampling in order to determine the IGF-1 concentration by the radioimmunoassay (RIA). Colostrum was sampled at 2, 14 and 26 hours (1st, 2nd and 3rd colostrum) after calving, while milk and venous blood were taken 10 days after calving. The concentration of IGF-1 was the highest in the 1 st colostrum and decreased significantly with each subsequent sampling, so the lowest concentrations were detected in milk sampled 10 days after calving. High concentrations of IGF-1 observed in colostrum, especially in the 1st colostrum, reflect its potential for eventually use in the treatment of various intestinal diseases. However, further research should determine the conditions and limitations of its application. On the other hand, additional research is needed to determine whether IGF-1 in milk has harmful effects on human health and whether it is necessary to limit the permitted presence of this hormone in cow milk.", publisher = "Faculty of Agriculture, Republic of Srpska, Bosnia", journal = "Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“", title = "Cow milk insulin like growth factor-1: risk or benefit for human health?", pages = "1196-1203", url = "https://hdl.handle.net/21.15107/rcub_veterinar_2274" }
Kirovski, D., Knežević, D., Golić, B., Kasagić, D., Jovanović, L., Bošnjaković, D., Trifković, J.,& Sladojević, Ž.. (2021). Cow milk insulin like growth factor-1: risk or benefit for human health?. in Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“ Faculty of Agriculture, Republic of Srpska, Bosnia., 1196-1203. https://hdl.handle.net/21.15107/rcub_veterinar_2274
Kirovski D, Knežević D, Golić B, Kasagić D, Jovanović L, Bošnjaković D, Trifković J, Sladojević Ž. Cow milk insulin like growth factor-1: risk or benefit for human health?. in Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“. 2021;:1196-1203. https://hdl.handle.net/21.15107/rcub_veterinar_2274 .
Kirovski, Danijela, Knežević, Dragan, Golić, Bojan, Kasagić, Dragan, Jovanović, Ljubomir, Bošnjaković, Dušan, Trifković, Julijana, Sladojević, Željko, "Cow milk insulin like growth factor-1: risk or benefit for human health?" in Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“ (2021):1196-1203, https://hdl.handle.net/21.15107/rcub_veterinar_2274 .