Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study
Aktivnost nekih biljnih eteričnih ulja protiv čestih izolata u veterinarskoj bakteriologiji - pilot studija
2021
Аутори
Zdravković, NemanjaRadanović, Oliver
Ninković, Milan
Savić Radovanović, Radoslava
Rajić-Savić, Nataša
Marjanović, Đorđe
Bojkovski, Jovan
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Antimicrobial therapy is important tool in fighting infectious
diseases. The significance of the role of antimicrobials in nature remains vastly
uninvestigated. Plants produce secondary metabolites for, among other functions,
natural protection against microbial infection. The aim of this research was to
investigate antimicrobial effects of 5 different essential oils and 5 main constituents
of plant essential oils toward some of the common veterinary microbial pathogens.
Plant etheric oils (EO) of oregano (Origanum vulgare L.), black caraway (Nigella
sativa L.), sandalwood (Santalum album L.), peppermint (Mentha balsamea Wild.)
and eucalyptus (Eucalyptus obliqua L'Hér.) and active components of etheric oils:
D-limonene, D-α pinene, thymol, carvacrol and cynamaldehyde were tested for
antimicriobial activity against referent strains of: Staphylococcus aureus,
Methicilin resistant S. aureus (MRSA), Escherichia coli; as well as against clinical
isolates of: Staphylococcus pseud...intermedius, E. coli, Pseudomonas aeruginosa
and yeast Candida sp. For each etheric oil and active compound minimal inhibitory
concentrations (MIC) are observed by method of broth microdilution. Results of
these investigations have shown that active components of the EO have stronger
antimicrobial effect than complete formulation of essential oils used in the study.
Among tested EOs the most potent was the peppermint etheric oil, while carvacrol
showed the strongest antimicrobial effect among active components of EO.
Interesting finding is that there was almost no difference among MICs between
referent S. aureus and MRSA.
Antimikrobna terapija je važno sredstvo u borbi protiv zaraznih bolesti. Značaj
uloge antimikrobnih sredstava u prirodi ostaje neistražen zbog prilagođavanja
patogena različitim oblicima rezistencije. Biljke proizvode sekundarne metabolite,
između ostalog i za prirodnu zaštitu od mikrobne infekcije. Cilj ovog istraživanja
bio je istražiti antimikrobne efekte 5 različitih esencijalnih ulja i 5 glavnih
sastojaka biljnih etarskih ulja na neke od uobičajenih veterinarskih mikrobnih
patogena. Biljna eterična ulja (EO) origana (Origanum vulgare L.), crnog kima
(Nigella sativa L.), sandalovine (Santalum album L.), nane (Mentha balsamea
Wild.) i eukaliptusa (Eucalyptus obliqua L'Hér.) kao i aktivnih komponenti: Dlimonen,
D-α pinen, timol, karvakrol i cinamaldehid testirani su na antimikrobnu
aktivnost protiv referentnih sojeva: Staphylococcus aureus, S. aureus rezistentne na
meticilin (MRSA), Escherichia coli kao i protiv kliničkih izolata: Staphylococcus
pseudintermedius, E. coli,... Pseudomonas aeruginosa i kvasca Candida sp. Za svako
eterično ulje i aktivno jedinjenje dobijene su minimalne inhibitorne koncentracije
(MIK) mikrodilucionom metodom u bujonu. Rezultati su pokazali da aktivne
komponente EO imaju jači antimikrobni efekat od EO sa istom odgovarajućom
dominantnom komponentom. Među testiranim EO najmoćnije je bilo eterično ulje
nane, dok je karvakrol pokazao najjači antimikrobni efekat među aktivnim
komponentama EO. Zanimljiv nalaz je da gotovo nije bilo razlike među MIK
između referentne S. aureus i MRSA.
Кључне речи:
carvacrol / MIC / pathogens / peppermint / Staphylococcus aureus / karvakrol / MIK / nanaИзвор:
13th International Symposium: Modern trends in livestock production, 2021, 552-560Издавач:
- Institute for Animal Husbandry, Belgrade-Zemun, Serbia
Колекције
Институција/група
Fakultet veterinarske medicineTY - CONF AU - Zdravković, Nemanja AU - Radanović, Oliver AU - Ninković, Milan AU - Savić Radovanović, Radoslava AU - Rajić-Savić, Nataša AU - Marjanović, Đorđe AU - Bojkovski, Jovan PY - 2021 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2311 AB - Antimicrobial therapy is important tool in fighting infectious diseases. The significance of the role of antimicrobials in nature remains vastly uninvestigated. Plants produce secondary metabolites for, among other functions, natural protection against microbial infection. The aim of this research was to investigate antimicrobial effects of 5 different essential oils and 5 main constituents of plant essential oils toward some of the common veterinary microbial pathogens. Plant etheric oils (EO) of oregano (Origanum vulgare L.), black caraway (Nigella sativa L.), sandalwood (Santalum album L.), peppermint (Mentha balsamea Wild.) and eucalyptus (Eucalyptus obliqua L'Hér.) and active components of etheric oils: D-limonene, D-α pinene, thymol, carvacrol and cynamaldehyde were tested for antimicriobial activity against referent strains of: Staphylococcus aureus, Methicilin resistant S. aureus (MRSA), Escherichia coli; as well as against clinical isolates of: Staphylococcus pseudintermedius, E. coli, Pseudomonas aeruginosa and yeast Candida sp. For each etheric oil and active compound minimal inhibitory concentrations (MIC) are observed by method of broth microdilution. Results of these investigations have shown that active components of the EO have stronger antimicrobial effect than complete formulation of essential oils used in the study. Among tested EOs the most potent was the peppermint etheric oil, while carvacrol showed the strongest antimicrobial effect among active components of EO. Interesting finding is that there was almost no difference among MICs between referent S. aureus and MRSA. AB - Antimikrobna terapija je važno sredstvo u borbi protiv zaraznih bolesti. Značaj uloge antimikrobnih sredstava u prirodi ostaje neistražen zbog prilagođavanja patogena različitim oblicima rezistencije. Biljke proizvode sekundarne metabolite, između ostalog i za prirodnu zaštitu od mikrobne infekcije. Cilj ovog istraživanja bio je istražiti antimikrobne efekte 5 različitih esencijalnih ulja i 5 glavnih sastojaka biljnih etarskih ulja na neke od uobičajenih veterinarskih mikrobnih patogena. Biljna eterična ulja (EO) origana (Origanum vulgare L.), crnog kima (Nigella sativa L.), sandalovine (Santalum album L.), nane (Mentha balsamea Wild.) i eukaliptusa (Eucalyptus obliqua L'Hér.) kao i aktivnih komponenti: Dlimonen, D-α pinen, timol, karvakrol i cinamaldehid testirani su na antimikrobnu aktivnost protiv referentnih sojeva: Staphylococcus aureus, S. aureus rezistentne na meticilin (MRSA), Escherichia coli kao i protiv kliničkih izolata: Staphylococcus pseudintermedius, E. coli, Pseudomonas aeruginosa i kvasca Candida sp. Za svako eterično ulje i aktivno jedinjenje dobijene su minimalne inhibitorne koncentracije (MIK) mikrodilucionom metodom u bujonu. Rezultati su pokazali da aktivne komponente EO imaju jači antimikrobni efekat od EO sa istom odgovarajućom dominantnom komponentom. Među testiranim EO najmoćnije je bilo eterično ulje nane, dok je karvakrol pokazao najjači antimikrobni efekat među aktivnim komponentama EO. Zanimljiv nalaz je da gotovo nije bilo razlike među MIK između referentne S. aureus i MRSA. PB - Institute for Animal Husbandry, Belgrade-Zemun, Serbia C3 - 13th International Symposium: Modern trends in livestock production T1 - Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study T1 - Aktivnost nekih biljnih eteričnih ulja protiv čestih izolata u veterinarskoj bakteriologiji - pilot studija SP - 552 EP - 560 UR - https://hdl.handle.net/21.15107/rcub_veterinar_2311 ER -
@conference{ author = "Zdravković, Nemanja and Radanović, Oliver and Ninković, Milan and Savić Radovanović, Radoslava and Rajić-Savić, Nataša and Marjanović, Đorđe and Bojkovski, Jovan", year = "2021", abstract = "Antimicrobial therapy is important tool in fighting infectious diseases. The significance of the role of antimicrobials in nature remains vastly uninvestigated. Plants produce secondary metabolites for, among other functions, natural protection against microbial infection. The aim of this research was to investigate antimicrobial effects of 5 different essential oils and 5 main constituents of plant essential oils toward some of the common veterinary microbial pathogens. Plant etheric oils (EO) of oregano (Origanum vulgare L.), black caraway (Nigella sativa L.), sandalwood (Santalum album L.), peppermint (Mentha balsamea Wild.) and eucalyptus (Eucalyptus obliqua L'Hér.) and active components of etheric oils: D-limonene, D-α pinene, thymol, carvacrol and cynamaldehyde were tested for antimicriobial activity against referent strains of: Staphylococcus aureus, Methicilin resistant S. aureus (MRSA), Escherichia coli; as well as against clinical isolates of: Staphylococcus pseudintermedius, E. coli, Pseudomonas aeruginosa and yeast Candida sp. For each etheric oil and active compound minimal inhibitory concentrations (MIC) are observed by method of broth microdilution. Results of these investigations have shown that active components of the EO have stronger antimicrobial effect than complete formulation of essential oils used in the study. Among tested EOs the most potent was the peppermint etheric oil, while carvacrol showed the strongest antimicrobial effect among active components of EO. Interesting finding is that there was almost no difference among MICs between referent S. aureus and MRSA., Antimikrobna terapija je važno sredstvo u borbi protiv zaraznih bolesti. Značaj uloge antimikrobnih sredstava u prirodi ostaje neistražen zbog prilagođavanja patogena različitim oblicima rezistencije. Biljke proizvode sekundarne metabolite, između ostalog i za prirodnu zaštitu od mikrobne infekcije. Cilj ovog istraživanja bio je istražiti antimikrobne efekte 5 različitih esencijalnih ulja i 5 glavnih sastojaka biljnih etarskih ulja na neke od uobičajenih veterinarskih mikrobnih patogena. Biljna eterična ulja (EO) origana (Origanum vulgare L.), crnog kima (Nigella sativa L.), sandalovine (Santalum album L.), nane (Mentha balsamea Wild.) i eukaliptusa (Eucalyptus obliqua L'Hér.) kao i aktivnih komponenti: Dlimonen, D-α pinen, timol, karvakrol i cinamaldehid testirani su na antimikrobnu aktivnost protiv referentnih sojeva: Staphylococcus aureus, S. aureus rezistentne na meticilin (MRSA), Escherichia coli kao i protiv kliničkih izolata: Staphylococcus pseudintermedius, E. coli, Pseudomonas aeruginosa i kvasca Candida sp. Za svako eterično ulje i aktivno jedinjenje dobijene su minimalne inhibitorne koncentracije (MIK) mikrodilucionom metodom u bujonu. Rezultati su pokazali da aktivne komponente EO imaju jači antimikrobni efekat od EO sa istom odgovarajućom dominantnom komponentom. Među testiranim EO najmoćnije je bilo eterično ulje nane, dok je karvakrol pokazao najjači antimikrobni efekat među aktivnim komponentama EO. Zanimljiv nalaz je da gotovo nije bilo razlike među MIK između referentne S. aureus i MRSA.", publisher = "Institute for Animal Husbandry, Belgrade-Zemun, Serbia", journal = "13th International Symposium: Modern trends in livestock production", title = "Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study, Aktivnost nekih biljnih eteričnih ulja protiv čestih izolata u veterinarskoj bakteriologiji - pilot studija", pages = "552-560", url = "https://hdl.handle.net/21.15107/rcub_veterinar_2311" }
Zdravković, N., Radanović, O., Ninković, M., Savić Radovanović, R., Rajić-Savić, N., Marjanović, Đ.,& Bojkovski, J.. (2021). Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study. in 13th International Symposium: Modern trends in livestock production Institute for Animal Husbandry, Belgrade-Zemun, Serbia., 552-560. https://hdl.handle.net/21.15107/rcub_veterinar_2311
Zdravković N, Radanović O, Ninković M, Savić Radovanović R, Rajić-Savić N, Marjanović Đ, Bojkovski J. Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study. in 13th International Symposium: Modern trends in livestock production. 2021;:552-560. https://hdl.handle.net/21.15107/rcub_veterinar_2311 .
Zdravković, Nemanja, Radanović, Oliver, Ninković, Milan, Savić Radovanović, Radoslava, Rajić-Savić, Nataša, Marjanović, Đorđe, Bojkovski, Jovan, "Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study" in 13th International Symposium: Modern trends in livestock production (2021):552-560, https://hdl.handle.net/21.15107/rcub_veterinar_2311 .