Приказ основних података о документу
Pathomorphological alterations and degree of reparatory processes in the liver of broilers treated with t-2 toxin
Patohistološke promene i stepen sanacionih procesa u jetri brojlera tretiranih T-2 toksinom
dc.creator | Šefer, Dragan | |
dc.creator | Knežević, Milijana | |
dc.creator | Sinovec, Snežana M. | |
dc.creator | Sinovec, Zlatan | |
dc.date.accessioned | 2020-06-03T12:47:45Z | |
dc.date.available | 2020-06-03T12:47:45Z | |
dc.date.issued | 2003 | |
dc.identifier.issn | 0567-8315 | |
dc.identifier.uri | https://vet-erinar.vet.bg.ac.rs/handle/123456789/233 | |
dc.description.abstract | The 42-day long trial was performed on a total of 48 Hybro broilers divided into four groups. After a 14 day pre-experimental period, the experimental groups were treated daily with T-2 toxin at 0.02 mg/kg BW for 7, 14 or 21 days respectively and a mixture of ethanol and physiological saline was administered to the control group of birds. Liver samples were taken after the period of toxin administration and the remaining birds from the control and experimental groups were normally fed and watered without toxin application until the end of the trial when liver samples were taken again. Histogenetic development of dystrophic and dyscyclic changes were found in the livers of the treated broilers. Morphological alterations of the liver were diverse in character, intensity and spread depending on the duration of exposure of broilers to the adverse effects of T-2 toxin, as well as the total quantity of toxin applied. The degree of the reparation varied depending on the duration of exposure to toxin, as well as the resting period. Evident reversible processes were found after short term exposure followed by a long resting period, while regeneration processes were not pronounced after chronic poisoning followed by a short resting period. | en |
dc.description.abstract | Ogled je izveden na 48 Hybro brojlera podeljenih u četiri grupe Eksperimentalne grupe su svakodnevno tretirane T-2 toksinom u količini od 0.02 mg/kg TM tokom 7, 14 ili 21 dana, dok je brojlerima kontrolne grupe aplikovana smeša etanola i fiziološkog rastvora. Uzorci jetre za patohistološka ispitivanja uzeti su nakon završetka tretmana, a preostali brojleri su hranjeni i pojeni bez aplikacije toksina do 42. dana kada su uzorci jetre ponovo uzeti. U jetri tretiranih brojlera utvrđen je histogenetski razvoj distrofičnih i discikličnih promena. Morfološke alteracije jetre razlikovale su se po karakteru, intenzitetu i raširenosti u zavisnosti od dužine ekspozicije brojlera, kao i od ukupne količine aplikovanog toksina. Stepen sanacionih procesa zavisio je od dužine ekspozicije brojlera, kao i od vremena oporavka. Reparacioni procesi su izraženi nakon kratkotrajnog delovanja T-2 toksina praćenog dugim periodom oporavka, dok se nakon hroničnog trovanja i kratkog vremena oporavka ne uočavaju regeneracioni procesi. | sr |
dc.publisher | Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd | |
dc.rights | openAccess | |
dc.source | Acta Veterinaria-Beograd | |
dc.subject | poultry T-2 toxin | en |
dc.subject | pathomorphological alterations | en |
dc.subject | reparatory processes | en |
dc.title | Pathomorphological alterations and degree of reparatory processes in the liver of broilers treated with t-2 toxin | en |
dc.title | Patohistološke promene i stepen sanacionih procesa u jetri brojlera tretiranih T-2 toksinom | sr |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Синовец, Златан; Кнежевић, Милијана; Шефер, Драган; Синовец, Снежана М.; Патохистолошке промене и степен санационих процеса у јетри бројлера третираних Т-2 токсином; Патохистолошке промене и степен санационих процеса у јетри бројлера третираних Т-2 токсином; | |
dc.citation.volume | 53 | |
dc.citation.issue | 1 | |
dc.citation.spage | 27 | |
dc.citation.epage | 34 | |
dc.citation.other | 53(1): 27-34 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000181775800004 | |
dc.identifier.doi | 10.2298/AVB0301027S | |
dc.identifier.scopus | 2-s2.0-0037255090 | |
dc.identifier.fulltext | https://vet-erinar.vet.bg.ac.rs/bitstream/id/832/232.pdf | |
dc.type.version | publishedVersion |