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Paraherquamide and 2-Deoxy-paraherquamide Distinguish Cholinergic Receptor Subtypes in Ascaris Muscle
(American Society for Pharmacology and Experimental Therapeutics (ASPET), 2002)
Paraherquamide is a novel natural anthelmintic product with a
mode of action that is incompletely characterized. Nicotine and
cholinergic-anthelmintic agonists of different chemical classes
were used to produce contraction ...
Levamisole receptor phosphorylation: effects of kinase antagonists on membrane potential responses in Ascaris suum suggest that CaM kinase and tyrosine kinase regulate sensitivity to levamisole
(The Company of Biologists, 2002)
A two-micropipette current-clamp technique was used
to record electrophysiological responses from the somatic
muscle of Ascaris suum. Levamisole and acetylcholine
were applied to the bag region of the muscle using ...
Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris
(Elsevier, 2004)
Three pharmacological subtypes of cholinergic receptors have been distinguished in Ascaris suum using a muscle contraction assay and
classical pharmacological techniques. The receptor subtypes are: a B-subtype (sensitive ...
Brief application of AF2 produces long lasting potentiation of nAChR responses in Ascaris suum
(Elsevier B.V., 2005)
Resistance of parasitic nematodes to the cholinergic anthelmintic levamisole is associated with a reduction in the proportion of time
that acetylcholine receptor ion-channels are in the open state decreasing the response ...