Corpus Callosum and Cerebellum Anomaly in a Puppy
Anomalije Corpus callosum i cerebeluma kod šteneta
Апстракт
This paper is aimed to present a corpus callosum and cerebellar anomaly with pathological findings in a 40-day-old, male, Golden Retriever puppy. It was stated that the dog rapidly deteriorated and died. On necropsy, after opening the skull, it was observed that the brain and cerebellum hemispheres were separated. In the detailed macroscopic examination, it was observed that the corpus callosum, interthalamic connections, which connect the brain hemispheres, were completely separated from each other. It was observed that the corpus callosum was more prominent in the right hemisphere but the anatomical structures of the left hemisphere were not evident. It was also observed that the hemispheres of the cerebellum were almost completely separated from the vermis region. It has been observed that brain connections can be achieved only by attachment between the midbrain and pons and continuing with the pons. Microscopic examination revealed no inflammatory reactions in the brain and cerebel...lum. Corpus callosum and cerebellar vermis anomalies in dogs have been reported before. However, split brain syndrome characterized by the loss of almost all connections of the brain and cerebellum in such severity that was observed in this case has not been previously reported.
Cilj studije je bio da predstavi anomaliju Corpus callosum i cerebeluma zajedno sa patološkim nalazom kod šteneta starosti 40 dana, rase zlatni Retriver. Prvi nalaz je bio da je pas brzo slabio i ubrzo uginuo. Prilikom obdukcije, posle otvaranja lobanje, uočeno je da su hemisfere velikog mozga i cerebeluma bile odvojene. Detaljnom makroskopskom analizom, uočeno je da su Corpus callosum, intertalamične veze koje povezuju hemisfere mozga, potpuno odvojene jedna od druge. Zapaženo je da je Corpus callosum naglašen u okviru desne hemisfere, ali i da se anatomske strukture u okviru leve hemisfere ne uočavaju. Isto tako su hemisfere cerebeluma bile skoro potpuno razdvojene od regiona medijalnog lobusa. Uočeno je da su veze u okviru mozga ostvarene samo prihvatanjem između srednjeg mozga i ponsa uz nastavak duž pons-a. Mikroskopskim pregledom nisu uočene bilo kakve zapaljenske reakcije u mozgu i u cerebelumu. U literaturi su opisane anomalije Corpus callosum-a i srednjeg lobusa cerebeluma kod... pasa. Međutim, do sada nije opisan u takvom obimu sindrom podeljenosti mozga, koji se karakteriše gubitkom povezanosti segmenata mozga i cerebeluma.
Кључне речи:
anomaly / brain / cerebellum / corpus callosum / dog / split brain syndromeИзвор:
Acta Veterinaria-Beograd, 2021, 70, 4, 526-532Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Ipek, Volkan AU - Kaplan, Oguzhan AU - Cinar, Aynur PY - 2021 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2399 AB - This paper is aimed to present a corpus callosum and cerebellar anomaly with pathological findings in a 40-day-old, male, Golden Retriever puppy. It was stated that the dog rapidly deteriorated and died. On necropsy, after opening the skull, it was observed that the brain and cerebellum hemispheres were separated. In the detailed macroscopic examination, it was observed that the corpus callosum, interthalamic connections, which connect the brain hemispheres, were completely separated from each other. It was observed that the corpus callosum was more prominent in the right hemisphere but the anatomical structures of the left hemisphere were not evident. It was also observed that the hemispheres of the cerebellum were almost completely separated from the vermis region. It has been observed that brain connections can be achieved only by attachment between the midbrain and pons and continuing with the pons. Microscopic examination revealed no inflammatory reactions in the brain and cerebellum. Corpus callosum and cerebellar vermis anomalies in dogs have been reported before. However, split brain syndrome characterized by the loss of almost all connections of the brain and cerebellum in such severity that was observed in this case has not been previously reported. AB - Cilj studije je bio da predstavi anomaliju Corpus callosum i cerebeluma zajedno sa patološkim nalazom kod šteneta starosti 40 dana, rase zlatni Retriver. Prvi nalaz je bio da je pas brzo slabio i ubrzo uginuo. Prilikom obdukcije, posle otvaranja lobanje, uočeno je da su hemisfere velikog mozga i cerebeluma bile odvojene. Detaljnom makroskopskom analizom, uočeno je da su Corpus callosum, intertalamične veze koje povezuju hemisfere mozga, potpuno odvojene jedna od druge. Zapaženo je da je Corpus callosum naglašen u okviru desne hemisfere, ali i da se anatomske strukture u okviru leve hemisfere ne uočavaju. Isto tako su hemisfere cerebeluma bile skoro potpuno razdvojene od regiona medijalnog lobusa. Uočeno je da su veze u okviru mozga ostvarene samo prihvatanjem između srednjeg mozga i ponsa uz nastavak duž pons-a. Mikroskopskim pregledom nisu uočene bilo kakve zapaljenske reakcije u mozgu i u cerebelumu. U literaturi su opisane anomalije Corpus callosum-a i srednjeg lobusa cerebeluma kod pasa. Međutim, do sada nije opisan u takvom obimu sindrom podeljenosti mozga, koji se karakteriše gubitkom povezanosti segmenata mozga i cerebeluma. T2 - Acta Veterinaria-Beograd T1 - Corpus Callosum and Cerebellum Anomaly in a Puppy T1 - Anomalije Corpus callosum i cerebeluma kod šteneta VL - 70 IS - 4 SP - 526 EP - 532 DO - 10.2478/acve-2020-0040 ER -
@article{ author = "Ipek, Volkan and Kaplan, Oguzhan and Cinar, Aynur", year = "2021", abstract = "This paper is aimed to present a corpus callosum and cerebellar anomaly with pathological findings in a 40-day-old, male, Golden Retriever puppy. It was stated that the dog rapidly deteriorated and died. On necropsy, after opening the skull, it was observed that the brain and cerebellum hemispheres were separated. In the detailed macroscopic examination, it was observed that the corpus callosum, interthalamic connections, which connect the brain hemispheres, were completely separated from each other. It was observed that the corpus callosum was more prominent in the right hemisphere but the anatomical structures of the left hemisphere were not evident. It was also observed that the hemispheres of the cerebellum were almost completely separated from the vermis region. It has been observed that brain connections can be achieved only by attachment between the midbrain and pons and continuing with the pons. Microscopic examination revealed no inflammatory reactions in the brain and cerebellum. Corpus callosum and cerebellar vermis anomalies in dogs have been reported before. However, split brain syndrome characterized by the loss of almost all connections of the brain and cerebellum in such severity that was observed in this case has not been previously reported., Cilj studije je bio da predstavi anomaliju Corpus callosum i cerebeluma zajedno sa patološkim nalazom kod šteneta starosti 40 dana, rase zlatni Retriver. Prvi nalaz je bio da je pas brzo slabio i ubrzo uginuo. Prilikom obdukcije, posle otvaranja lobanje, uočeno je da su hemisfere velikog mozga i cerebeluma bile odvojene. Detaljnom makroskopskom analizom, uočeno je da su Corpus callosum, intertalamične veze koje povezuju hemisfere mozga, potpuno odvojene jedna od druge. Zapaženo je da je Corpus callosum naglašen u okviru desne hemisfere, ali i da se anatomske strukture u okviru leve hemisfere ne uočavaju. Isto tako su hemisfere cerebeluma bile skoro potpuno razdvojene od regiona medijalnog lobusa. Uočeno je da su veze u okviru mozga ostvarene samo prihvatanjem između srednjeg mozga i ponsa uz nastavak duž pons-a. Mikroskopskim pregledom nisu uočene bilo kakve zapaljenske reakcije u mozgu i u cerebelumu. U literaturi su opisane anomalije Corpus callosum-a i srednjeg lobusa cerebeluma kod pasa. Međutim, do sada nije opisan u takvom obimu sindrom podeljenosti mozga, koji se karakteriše gubitkom povezanosti segmenata mozga i cerebeluma.", journal = "Acta Veterinaria-Beograd", title = "Corpus Callosum and Cerebellum Anomaly in a Puppy, Anomalije Corpus callosum i cerebeluma kod šteneta", volume = "70", number = "4", pages = "526-532", doi = "10.2478/acve-2020-0040" }
Ipek, V., Kaplan, O.,& Cinar, A.. (2021). Corpus Callosum and Cerebellum Anomaly in a Puppy. in Acta Veterinaria-Beograd, 70(4), 526-532. https://doi.org/10.2478/acve-2020-0040
Ipek V, Kaplan O, Cinar A. Corpus Callosum and Cerebellum Anomaly in a Puppy. in Acta Veterinaria-Beograd. 2021;70(4):526-532. doi:10.2478/acve-2020-0040 .
Ipek, Volkan, Kaplan, Oguzhan, Cinar, Aynur, "Corpus Callosum and Cerebellum Anomaly in a Puppy" in Acta Veterinaria-Beograd, 70, no. 4 (2021):526-532, https://doi.org/10.2478/acve-2020-0040 . .