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dc.creatorLukić, Ivana
dc.creatorPajnik, Jelena
dc.creatorNišavić, Jakov
dc.creatorTadić, Vanja
dc.creatorVági, Erika
dc.creatorSzekely, Edit
dc.creatorŽižović, Irena
dc.date.accessioned2022-05-23T08:31:01Z
dc.date.available2022-05-23T08:31:01Z
dc.date.issued2022
dc.identifier.issn2227-9717
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/5113
dc.identifier.urihttps://vet-erinar.vet.bg.ac.rs/handle/123456789/2457
dc.description.abstractThe integrated supercritical fluid extraction–impregnation process (SFE-SSI) was performed to fabricate material with antiviral properties against the herpes simplex virus (HSV). Cotton gauze and starch/chitosan polymer films (SCF) were impregnated with components extracted from Melissa officinalis at 10 MPa and 40 °C using a green medium, supercritical carbon dioxide (scCO2). The influences of the processing mode regarding the flow of the supercritical fluid through the system, and the mass ratio of the plant material and the solid carrier, on the impregnation yield of M. officinalis extract were studied. The results revealed that the introduction of a fresh amount of CO2 into the system enabled the highest impregnation yield of 2.24% for cotton gauze and 8.71% for SCF. The presence of M. officinalis extract on the surface of both impregnated cotton gaze and SCF was confirmed by FTIR and GC analyses after the re-extraction of the impregnated samples. The M. officinalis impregnated materials showed a strong inhibitory effect against Bovine herpesvirus type 1 (BHV-1).sr
dc.language.isoensr
dc.publisherMDPIsr
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200135/RS//sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200287/RS//sr
dc.rightsopenAccesssr
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceProcessessr
dc.subjectantiviral activitysr
dc.subjectMelissa officinalissr
dc.subjectsupercritical extractionsr
dc.subjectsupercritical impregnationsr
dc.titleApplication of the Integrated Supercritical Fluid Extraction–Impregnation Process (SFE-SSI) for Development of Materials with Antiviral Propertiessr
dc.typearticlesr
dc.rights.licenseBYsr
dc.citation.volume10
dc.citation.issue4
dc.citation.spage680
dc.citation.rankM22~
dc.identifier.wos00078613190000
dc.identifier.doi10.3390/pr10040680
dc.identifier.scopus2-s2.0-85128283805
dc.identifier.fulltexthttp://veterinar.vet.bg.ac.rs/bitstream/id/6903/Application_of_the_Integrated_pub_2022.pdf
dc.type.versionpublishedVersionsr


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