Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens
Contributors
Đurđević, BiljanaPajić, Marko
Knežević, Slobodan
Polaček, Vladimir
Nešić, Ksenija
Vučićević, Ivana
Ostojić Andrić, Dušica
Article (Published version)
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This experiment was performed to investigate the protective effect of a new combined adsorbent (bentonite + yeast cellwall extract) previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with aflatoxinB1 until 21 days of age. A total of 96 one-day old Ross 308 hybrid broiler chickens were divided into four groups: group I (control),group II (5 g/kg adsorbent), group III (5 g/kg adsorbent + 2 mg/kg aflatoxin B1), and group IV (2 mg/kg aflatoxin B1). Grossly,AFB1 and AFB1+adsorbent fed birds showed enlargement, friable texture of liver and enlargement and pallorness of kidneys. Spleenrevealed size reduction. No gross-pathological changes were observed in control and group II. Histopathologically, lesions wereobserved in aflatoxicated groups. Liver revealed vacuolar cell degeneration, periportal and perivascular infiltration of mononuclearcells. Kidneys revealed mild to moderate degree of haemorrhages, tubular epithelial necrosis and infi...ltration of mononuclearcells along with heterophils. In group IV, catarrhal enteritis characterized by desquamation of epithelial cells were found in theduodenum. A milder form of gross and histopathological lesions was seen in group III. In conclusion, the present study revealedthat supplementation of a new combined toxin binder product in the concentration of 5 g/kg could not completely ameliorateaflatoxicity in broilers, although it met the stringent European regulation requirements for the minimum of 90% aflatoxin bindingefficiency in in vitro study.
Keywords:
Adsorbent / Aflatoxin B1 / Broilers / Pathological lesionsSource:
2022, 28, 4, 185-191Publisher:
- Kafkas University, Faculty of Veterinary Medicine
Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200031 (Scientific Institute of Veterinary Medicine 'Novi Sad', Novi Sad) (RS-MESTD-inst-2020-200031)
DOI: 10.9775/kvfd.2021.26654
ISSN: 1300-6045
WoS: 000744658000001
Scopus: 2-s2.0-85127980664
URI
https://repo.niv.ns.ac.rs/xmlui/handle/123456789/470https://vet-erinar.vet.bg.ac.rs/handle/123456789/2462
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Fakultet veterinarske medicineTY - JOUR PY - 2022 UR - https://repo.niv.ns.ac.rs/xmlui/handle/123456789/470 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2462 AB - This experiment was performed to investigate the protective effect of a new combined adsorbent (bentonite + yeast cellwall extract) previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with aflatoxinB1 until 21 days of age. A total of 96 one-day old Ross 308 hybrid broiler chickens were divided into four groups: group I (control),group II (5 g/kg adsorbent), group III (5 g/kg adsorbent + 2 mg/kg aflatoxin B1), and group IV (2 mg/kg aflatoxin B1). Grossly,AFB1 and AFB1+adsorbent fed birds showed enlargement, friable texture of liver and enlargement and pallorness of kidneys. Spleenrevealed size reduction. No gross-pathological changes were observed in control and group II. Histopathologically, lesions wereobserved in aflatoxicated groups. Liver revealed vacuolar cell degeneration, periportal and perivascular infiltration of mononuclearcells. Kidneys revealed mild to moderate degree of haemorrhages, tubular epithelial necrosis and infiltration of mononuclearcells along with heterophils. In group IV, catarrhal enteritis characterized by desquamation of epithelial cells were found in theduodenum. A milder form of gross and histopathological lesions was seen in group III. In conclusion, the present study revealedthat supplementation of a new combined toxin binder product in the concentration of 5 g/kg could not completely ameliorateaflatoxicity in broilers, although it met the stringent European regulation requirements for the minimum of 90% aflatoxin bindingefficiency in in vitro study. PB - Kafkas University, Faculty of Veterinary Medicine T1 - Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens VL - 28 IS - 4 SP - 185 EP - 191 DO - 10.9775/kvfd.2021.26654 ER -
@article{ year = "2022", abstract = "This experiment was performed to investigate the protective effect of a new combined adsorbent (bentonite + yeast cellwall extract) previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with aflatoxinB1 until 21 days of age. A total of 96 one-day old Ross 308 hybrid broiler chickens were divided into four groups: group I (control),group II (5 g/kg adsorbent), group III (5 g/kg adsorbent + 2 mg/kg aflatoxin B1), and group IV (2 mg/kg aflatoxin B1). Grossly,AFB1 and AFB1+adsorbent fed birds showed enlargement, friable texture of liver and enlargement and pallorness of kidneys. Spleenrevealed size reduction. No gross-pathological changes were observed in control and group II. Histopathologically, lesions wereobserved in aflatoxicated groups. Liver revealed vacuolar cell degeneration, periportal and perivascular infiltration of mononuclearcells. Kidneys revealed mild to moderate degree of haemorrhages, tubular epithelial necrosis and infiltration of mononuclearcells along with heterophils. In group IV, catarrhal enteritis characterized by desquamation of epithelial cells were found in theduodenum. A milder form of gross and histopathological lesions was seen in group III. In conclusion, the present study revealedthat supplementation of a new combined toxin binder product in the concentration of 5 g/kg could not completely ameliorateaflatoxicity in broilers, although it met the stringent European regulation requirements for the minimum of 90% aflatoxin bindingefficiency in in vitro study.", publisher = "Kafkas University, Faculty of Veterinary Medicine", title = "Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens", volume = "28", number = "4", pages = "185-191", doi = "10.9775/kvfd.2021.26654" }
(2022). Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens. Kafkas University, Faculty of Veterinary Medicine., 28(4), 185-191. https://doi.org/10.9775/kvfd.2021.26654
Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens. 2022;28(4):185-191. doi:10.9775/kvfd.2021.26654 .
"Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens", 28, no. 4 (2022):185-191, https://doi.org/10.9775/kvfd.2021.26654 . .