Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks
Аутори
Stefanović, DarkoMarinković, Darko
Trailović, Saša
Vasiljević, Marko
Farkaš, Hunor
Raj, Jog
Tolimir, Nataša
Radulović, Stamen
Nešić, Vladimir
Nedeljković-Trailović, Jelena
Petrujkić, Branko
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
This experimental study was conducted to determine the ability of a novel mycotoxins detoxification agent (MR) at a concentration of 0.2% to reduce the toxicity of aflatoxin B1 (AFB1) or T-2 toxin, alone or in combination, and to examine its effect on performance, pathohistological changes (PH) and the residue of these toxins in the tissues of broiler chicks. A total of 96 broiler chicks were divided into eight equal groups: group C, which served as control (without any additives); group MR, which received the novel detoxification agent (supplemented with 0.2%); group E-I (0.1 mg AFB1/kg of diet); group E-II (0.1 mg AFB1/kg of diet + MR 0.2%); group E-III (0.5 mg T-2 toxin/kg of diet); group E-IV (0.5 mg T-2 toxin/kg of diet + 0.2% MR); group E-V (combination of 0.1 mg AFB1/kg, 0.5 mg T-2 toxin/kg of diet); and group E-VI (combination of 0.1 mg AFB1/kg, 0.5 mg T-2 toxin + 0.2% MR). Results indicate that feeds containing AFB1 and T-2 toxin, alone or in combination, adversely affected th...e health and performance of poultry. However, the addition of MR to diets containing AFB1 and T-2 toxin singly and in combination exerted a positive effect on body weight, feed intake, weight gain, feed efficiency and microscopic lesions in visceral organs. Residual concentration of AFB1 in liver samples was significantly (p < 0.05) decreased when chicks were fed diets supplemented with 0.2% of MR.
Кључне речи:
AFB1; T-2 toxin; broiler chicks; health status; detoxification agentИзвор:
Microorganisms, 2023, 11, 3, 574-Издавач:
- MDPI
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200143 (Универзитет у Београду, Факултет ветеринарске медицине) (RS-MESTD-inst-2020-200143)
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Stefanović, Darko AU - Marinković, Darko AU - Trailović, Saša AU - Vasiljević, Marko AU - Farkaš, Hunor AU - Raj, Jog AU - Tolimir, Nataša AU - Radulović, Stamen AU - Nešić, Vladimir AU - Nedeljković-Trailović, Jelena AU - Petrujkić, Branko PY - 2023 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2629 AB - This experimental study was conducted to determine the ability of a novel mycotoxins detoxification agent (MR) at a concentration of 0.2% to reduce the toxicity of aflatoxin B1 (AFB1) or T-2 toxin, alone or in combination, and to examine its effect on performance, pathohistological changes (PH) and the residue of these toxins in the tissues of broiler chicks. A total of 96 broiler chicks were divided into eight equal groups: group C, which served as control (without any additives); group MR, which received the novel detoxification agent (supplemented with 0.2%); group E-I (0.1 mg AFB1/kg of diet); group E-II (0.1 mg AFB1/kg of diet + MR 0.2%); group E-III (0.5 mg T-2 toxin/kg of diet); group E-IV (0.5 mg T-2 toxin/kg of diet + 0.2% MR); group E-V (combination of 0.1 mg AFB1/kg, 0.5 mg T-2 toxin/kg of diet); and group E-VI (combination of 0.1 mg AFB1/kg, 0.5 mg T-2 toxin + 0.2% MR). Results indicate that feeds containing AFB1 and T-2 toxin, alone or in combination, adversely affected the health and performance of poultry. However, the addition of MR to diets containing AFB1 and T-2 toxin singly and in combination exerted a positive effect on body weight, feed intake, weight gain, feed efficiency and microscopic lesions in visceral organs. Residual concentration of AFB1 in liver samples was significantly (p < 0.05) decreased when chicks were fed diets supplemented with 0.2% of MR. PB - MDPI T2 - Microorganisms T1 - Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks VL - 11 IS - 3 SP - 574 DO - 10.3390/microorganisms11030574 ER -
@article{ author = "Stefanović, Darko and Marinković, Darko and Trailović, Saša and Vasiljević, Marko and Farkaš, Hunor and Raj, Jog and Tolimir, Nataša and Radulović, Stamen and Nešić, Vladimir and Nedeljković-Trailović, Jelena and Petrujkić, Branko", year = "2023", abstract = "This experimental study was conducted to determine the ability of a novel mycotoxins detoxification agent (MR) at a concentration of 0.2% to reduce the toxicity of aflatoxin B1 (AFB1) or T-2 toxin, alone or in combination, and to examine its effect on performance, pathohistological changes (PH) and the residue of these toxins in the tissues of broiler chicks. A total of 96 broiler chicks were divided into eight equal groups: group C, which served as control (without any additives); group MR, which received the novel detoxification agent (supplemented with 0.2%); group E-I (0.1 mg AFB1/kg of diet); group E-II (0.1 mg AFB1/kg of diet + MR 0.2%); group E-III (0.5 mg T-2 toxin/kg of diet); group E-IV (0.5 mg T-2 toxin/kg of diet + 0.2% MR); group E-V (combination of 0.1 mg AFB1/kg, 0.5 mg T-2 toxin/kg of diet); and group E-VI (combination of 0.1 mg AFB1/kg, 0.5 mg T-2 toxin + 0.2% MR). Results indicate that feeds containing AFB1 and T-2 toxin, alone or in combination, adversely affected the health and performance of poultry. However, the addition of MR to diets containing AFB1 and T-2 toxin singly and in combination exerted a positive effect on body weight, feed intake, weight gain, feed efficiency and microscopic lesions in visceral organs. Residual concentration of AFB1 in liver samples was significantly (p < 0.05) decreased when chicks were fed diets supplemented with 0.2% of MR.", publisher = "MDPI", journal = "Microorganisms", title = "Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks", volume = "11", number = "3", pages = "574", doi = "10.3390/microorganisms11030574" }
Stefanović, D., Marinković, D., Trailović, S., Vasiljević, M., Farkaš, H., Raj, J., Tolimir, N., Radulović, S., Nešić, V., Nedeljković-Trailović, J.,& Petrujkić, B.. (2023). Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks. in Microorganisms MDPI., 11(3), 574. https://doi.org/10.3390/microorganisms11030574
Stefanović D, Marinković D, Trailović S, Vasiljević M, Farkaš H, Raj J, Tolimir N, Radulović S, Nešić V, Nedeljković-Trailović J, Petrujkić B. Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks. in Microorganisms. 2023;11(3):574. doi:10.3390/microorganisms11030574 .
Stefanović, Darko, Marinković, Darko, Trailović, Saša, Vasiljević, Marko, Farkaš, Hunor, Raj, Jog, Tolimir, Nataša, Radulović, Stamen, Nešić, Vladimir, Nedeljković-Trailović, Jelena, Petrujkić, Branko, "Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks" in Microorganisms, 11, no. 3 (2023):574, https://doi.org/10.3390/microorganisms11030574 . .