The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs
Аутори
Ravić, BrankoDebeljak-Martacić, Jasmina
Pokimica, Biljana
Vidović, Nevena
Ranković, Slavica
Glibetić, Marija
Stepanović, Predrag
Popović, Tamara
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The synthesis, degradation, and reconstruction of the cell membrane as a metabolic pathway
of phospholipids is a constant and dynamic process. Fatty acids as bioactive lipid components of
plasma and erythrocyte phospholipids as structural lipids have biological roles in the integrity of
cell membranes. Fatty acids, depending on the chain length, the degree of saturation, and the
synthesis pathways, can alleviate inflammation and oxidative stress caused by excessive exercise.
Considering that changing food intake or diet can influence fatty acid phospholipid metabolism,
our study aimed to determine the potential benefits of fish-based diets in working (police) dogs
undergoing intensive training concerning bioactive lipids such as fatty acids, phospholipids of
plasma, and erythrocytes. Fatty acid esters’ composition of plasma and erythrocyte phospholipids
as a bioactive lipids, in addition to markers of oxidative stress and metabolic parameters, were
analysed by GC chromatograp...hy. The food was well tolerated by all dogs, and the compliance to the
diet was high throughout the study. After the treatment with fish-based food, blood glucose, total,
and LDL cholesterol levels were significantly reduced, indicating positive biochemical profiles of
dogs. Correlations of fatty acid phospholipid compositions between plasma and erythrocytes have
shown that both plasma and erythrocytes could represent markers of omega-3 eicosapentaenoic and
docosahexaenoic acid intake levels in dogs. Morover, fish-based food supplementation caused a
significant reduction in lipid peroxidation markers. The enrichment of dogs’ diets with marine fish
could improve oxidative status and improve roles and status of bioactive lipids, such as membrane
phospholipids and fatty acids, as its components in plasma and erythrocytes in police dogs exposed to intensive exercise.
Кључне речи:
bioactive lipids / fatty acids / omega-3 / oxidative stress / working dogsИзвор:
Biomolecules, 2022, 12, 8, 1092-Издавач:
- MDPI
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200015 (Универзитет у Београду, Институт за медицинска истраживања) (RS-MESTD-inst-2020-200015)
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Ravić, Branko AU - Debeljak-Martacić, Jasmina AU - Pokimica, Biljana AU - Vidović, Nevena AU - Ranković, Slavica AU - Glibetić, Marija AU - Stepanović, Predrag AU - Popović, Tamara PY - 2022 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2834 AB - The synthesis, degradation, and reconstruction of the cell membrane as a metabolic pathway of phospholipids is a constant and dynamic process. Fatty acids as bioactive lipid components of plasma and erythrocyte phospholipids as structural lipids have biological roles in the integrity of cell membranes. Fatty acids, depending on the chain length, the degree of saturation, and the synthesis pathways, can alleviate inflammation and oxidative stress caused by excessive exercise. Considering that changing food intake or diet can influence fatty acid phospholipid metabolism, our study aimed to determine the potential benefits of fish-based diets in working (police) dogs undergoing intensive training concerning bioactive lipids such as fatty acids, phospholipids of plasma, and erythrocytes. Fatty acid esters’ composition of plasma and erythrocyte phospholipids as a bioactive lipids, in addition to markers of oxidative stress and metabolic parameters, were analysed by GC chromatography. The food was well tolerated by all dogs, and the compliance to the diet was high throughout the study. After the treatment with fish-based food, blood glucose, total, and LDL cholesterol levels were significantly reduced, indicating positive biochemical profiles of dogs. Correlations of fatty acid phospholipid compositions between plasma and erythrocytes have shown that both plasma and erythrocytes could represent markers of omega-3 eicosapentaenoic and docosahexaenoic acid intake levels in dogs. Morover, fish-based food supplementation caused a significant reduction in lipid peroxidation markers. The enrichment of dogs’ diets with marine fish could improve oxidative status and improve roles and status of bioactive lipids, such as membrane phospholipids and fatty acids, as its components in plasma and erythrocytes in police dogs exposed to intensive exercise. PB - MDPI T2 - Biomolecules T1 - The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs VL - 12 IS - 8 SP - 1092 DO - 10.3390/biom12081092 ER -
@article{ author = "Ravić, Branko and Debeljak-Martacić, Jasmina and Pokimica, Biljana and Vidović, Nevena and Ranković, Slavica and Glibetić, Marija and Stepanović, Predrag and Popović, Tamara", year = "2022", abstract = "The synthesis, degradation, and reconstruction of the cell membrane as a metabolic pathway of phospholipids is a constant and dynamic process. Fatty acids as bioactive lipid components of plasma and erythrocyte phospholipids as structural lipids have biological roles in the integrity of cell membranes. Fatty acids, depending on the chain length, the degree of saturation, and the synthesis pathways, can alleviate inflammation and oxidative stress caused by excessive exercise. Considering that changing food intake or diet can influence fatty acid phospholipid metabolism, our study aimed to determine the potential benefits of fish-based diets in working (police) dogs undergoing intensive training concerning bioactive lipids such as fatty acids, phospholipids of plasma, and erythrocytes. Fatty acid esters’ composition of plasma and erythrocyte phospholipids as a bioactive lipids, in addition to markers of oxidative stress and metabolic parameters, were analysed by GC chromatography. The food was well tolerated by all dogs, and the compliance to the diet was high throughout the study. After the treatment with fish-based food, blood glucose, total, and LDL cholesterol levels were significantly reduced, indicating positive biochemical profiles of dogs. Correlations of fatty acid phospholipid compositions between plasma and erythrocytes have shown that both plasma and erythrocytes could represent markers of omega-3 eicosapentaenoic and docosahexaenoic acid intake levels in dogs. Morover, fish-based food supplementation caused a significant reduction in lipid peroxidation markers. The enrichment of dogs’ diets with marine fish could improve oxidative status and improve roles and status of bioactive lipids, such as membrane phospholipids and fatty acids, as its components in plasma and erythrocytes in police dogs exposed to intensive exercise.", publisher = "MDPI", journal = "Biomolecules", title = "The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs", volume = "12", number = "8", pages = "1092", doi = "10.3390/biom12081092" }
Ravić, B., Debeljak-Martacić, J., Pokimica, B., Vidović, N., Ranković, S., Glibetić, M., Stepanović, P.,& Popović, T.. (2022). The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs. in Biomolecules MDPI., 12(8), 1092. https://doi.org/10.3390/biom12081092
Ravić B, Debeljak-Martacić J, Pokimica B, Vidović N, Ranković S, Glibetić M, Stepanović P, Popović T. The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs. in Biomolecules. 2022;12(8):1092. doi:10.3390/biom12081092 .
Ravić, Branko, Debeljak-Martacić, Jasmina, Pokimica, Biljana, Vidović, Nevena, Ranković, Slavica, Glibetić, Marija, Stepanović, Predrag, Popović, Tamara, "The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs" in Biomolecules, 12, no. 8 (2022):1092, https://doi.org/10.3390/biom12081092 . .