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Rezistencija na anthelmintike - rasprostranjenost, otkrivanje i mere za njeno preveniranje

dc.creatorDimitrijević, Sanda
dc.creatorIlić, Tamara
dc.date.accessioned2020-06-03T12:52:18Z
dc.date.available2020-06-03T12:52:18Z
dc.date.issued2004
dc.identifier.issn0350-2457
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/298
dc.description.abstractAnthelmints are preparations originating from different chemical groups which affect parasites in the way that they disrupt their cellular integrity structure or metabolism. Even though a wide specter of efficient anthelmints is currently available, which can be successfully applied in the fight against a large number of parasitoses, their increasing or incorrect implementation by animal owners can become inefficient and harmful. The long-term use of one and the same anthelmints or a preparation that has a similar mode of action, results in the creating of parasite resistance to the drug. Once established, such resistance can last for several years, or it can disappear under the influence of selection and genetic drifting, which acts in a way that it returns sensitivity to the population. Analyzing certain groups of parasites, it has been established that resistance to antiparasitics among them develops at various paces. Coccidia and ectoparasites especially quickly become resistant as a consequence of survival and favorization of resistant strains in the population. In helminths, resistance develops more slowly, mostly to drugs of the bensimidazole group. This is the very reason why it is of great importance to make the correct choice of therapy and prophylaxis of the topical helminthoses, and to conduct organized control measures to prevent the occurrence of resistance to drugs.en
dc.description.abstractAnthelmintici su preparati koji potiču iz različitih hemijskih grupa, i deluju na parazite na taj način što narušavaju njihov ćelijski integritet strukturu Hi metabolizam. lako je trenutno dostupan širok spektar efikasnih anthelmintika, koji uspešno mogu da se primenjuju u borbi protiv većeg broja parazitoza, ali, ukoliko ih vlasnici životinja učestalo ili pogrešno primenjuju može da bude neefikasno i štetno. Duža upotreba jednog istog anthelmintika ili sredstava koja imaju sličan mehanizam delovanja, ima kao posledicu stvaranje otpornosti parazita na lek. Jednom uspostavljena rezistencija može da potraje vise godina ili nestaje pod uticajem selekcije i genetičkog drifta, koji deluju na taj način što vraćaju osetljivost u populaciju. Analizirajući pojedine grupe parazita, ustanovljeno je da se rezistencija na antiparazitike, kod njih razvija različitom brzinom Kokcidije i ektoparaziti naročito brzo postaju rezistentni, kao posledica preživljavanja i favorizovanja otpornih sojeva u populaciji. Kod helminata rezistencija se sporije razvija, uglavnom na lekove iz grupe benzimidazola. Upravo zbog toga, od velikog značaja su pravilan izbor terapije i profilakse aktuelnih helmintoza, kao i organizovano sprovođenje mera kontrole u preveniranju rezistencije na lekove.sr
dc.publisherUniverzitet u Beogradu - Fakultet veterinarske medicine, Beograd
dc.rightsopenAccess
dc.sourceVeterinarski glasnik
dc.subjectresistanceen
dc.subjectanthelmintsen
dc.subjectprophylaxisen
dc.subjectanthelminticisr
dc.subjectrezistencijasr
dc.subjectprofilaksasr
dc.titleResistance to anthelmints: Distribution, detection and prophylactic measuresen
dc.titleRezistencija na anthelmintike - rasprostranjenost, otkrivanje i mere za njeno preveniranjesr
dc.typearticle
dc.rights.licenseBY
dcterms.abstractИлић, Тамара; Димитријевић, Санда;
dc.citation.volume58
dc.citation.issue5-6
dc.citation.spage685
dc.citation.epage692
dc.citation.other58(5-6): 685-692
dc.identifier.rcubconv_95
dc.type.versionpublishedVersion


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