Feline infectious peritonitis (FIP) in our section material

Abstract

Feline infectious peritonitis (FIP) has been diagnozed in our section material in 23 cats, 19 Persian and 4 domestic, of both sexes, aged between 5 months and 8 years. The majority of the infected population were animals under 20 months of age. The macroscopic finding in most cats was of granulomatous character, and large quantities of goldenyellow gelatinous exudate were observed in the stomach cavity of 7 animals, corresponding to the exudative form of FIP. Granulomas were in most cases located in the abdomen wall, liver, spleen, omentum and serous membrane of intestines, and the histological structure was characterized by fibrinoid-necrotic centers with numerous lymphocytes, monocytes, angioblasts and fibroblasts. Immunohistochemically, feline corona virus (FCV) antigens were exprimed in the cytoplasm of macrophages, more rarely in plasma cells in granulomas, and sometimes in necrotized areas.

Infektivni peritonitis mačaka (FIP) dijagnostikovan je u našem sekcionom materijalu kod 23 mačke, 19 persijskih i 4 domaće, oba pola, uzrasta između 5 meseci i 8 godina. Većinu inficirane populacije činile su životinje mlađe od 20 meseci. Makroskopski nalaz bio je kod većine mačaka granulomatoznog karaktera, a kod 7 životinja uočena je veća količina zlatno-žutog želatinoznog eksudata u trbušnoj duplji, što odgovara eksudativnoj formi FIP-a. Granulomi su bili smešteni u većini slučajeva u zidu abdomena, jetri slezini, omentumu i serozi creva, a histološka građa odlikovala se fibrinoidno-nekrotičnim centrima, sa mnogobrojnim limfocitima, monocitima angioblastima i fibroblastima. Imunohistohemijski, antigeni corona-virusa mačaka (FCV) eksprimirani su u citoplazmi makrofaga, ređe u plazma ćelijama u granulomima, a ponekad i u nekrotizovanim oblastima.