Function and importance of HSP 70 in metabolic stress in dairy cows in peripartal period

Abstract

Peripartal period in dairy cows includes 3 weeks ante partum and 3 weeks post partum (transition period). The transition period represents the most challenging phase in the life of dairy cows, because the body occurring metabolic, endocrine, immune and reproductive changes that affect the animal health and production efficiency. During the transition period (the late gestation and early lactation) in response to metabolic stress, in dairy cows can develop numerous pathophysiological mechanisms (inflammation, insulin resistance and metabolic adaptation). Numerous mechanisms are activated in the organism of dairy cows, the main role of which is maintenance of homeostatic and homeostatic functions of all tissues, organs and organ systems. In regulation of these processes, heat stress proteins HSP70 play a key role.