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Osnovni principi zaštite dobrobiti oglednih životinja

dc.creatorVučinić, Marijana
dc.date.accessioned2020-06-03T13:06:35Z
dc.date.available2020-06-03T13:06:35Z
dc.date.issued2007
dc.identifier.issn0350-2457
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/502
dc.description.abstractEthical considerations of animal protection and welfare require that the use of experimental animals is limited as much as possible. Animal experiments should only be performed when no alternative is available and when the benefit of the experiment outweighs the suffering of the animal. This review paper describes the basic principles for the ethical use of experimental animals. These are: "Three Rs rule" (replacement, reduction and refinement), "five freedoms" for animals and "Solna principles". "Replacement" means the substitution for conscious living higher animals of insentient material. "Reduction" means reduction in the numbers of animals used to obtain information of a given amount and precision. "Refinement" means any decrease in the incidence or severity of inhumane procedures applied to those animals which still have to be used. The "five freedoms" are: freedom from hunger and thirst, freedom from adverse environmental impacts, freedom from disease and injury, freedom to exhibit normal behavior and freedom from adverse mental states. "Solna principles" state that tests for regulatory purposes need to reflect the following: biological Relevance (meaningfulness and usefulness of a test for a particular purpose), Reliability (reproducibility of results within and between laboratories), and Regulatory acceptability (suitability of a test for risk assessment purposes (human health /environment).en
dc.description.abstractEtička načela zaštite dobrobiti oglednih životinja iz podtipa kičmenjaka nalažu da se njihova upotreba svede na najmanju moguću meru, ne samo iz etičkih, već i iz praktičnih razloga. Ogledi na kičmenjacima mogu da se sprovode samo ako ne postoje odgovarajući alternativni modeli i ako patnja životinja koje se koriste u ogledima može da se opravda koristima samog in vivo ogleda. U ovom radu, revijalnog karaktera, izneti su osnovni etički principi korišćenja oglednih životinja. Ti principi su: "3R pravilo", "pravilo 5 sloboda" i "Solna pravilo". Takozvano "3R pravilo" odnosi se na zamenu oglednih životinja iz podtipa kičmenjaka alternativnim životinjskim modelima na nižem stupnju evolutivnog razvoja, biljnim vrstama, životinjskim i biljnim kulturama ćelija i tkiva, izolovanim organima, fizičkim, mehaničkim, hemijskim modelima, kompjuterskim simulacijama, smanjenje broja životinja u ogledu i usavršavanje ogledne procedure do stepena na kojem je moguće potpuno izbeći ili umanjiti neprijatna telesna i emocionalna iskustva životinja u ogledu. "Solna pravilo" se odnosi na procenu biološke pogodnosti, ponovljivosti i prihvatljivosti in vivo ogleda i alternativnih animalnih modela.sr
dc.publisherUniverzitet u Beogradu - Fakultet veterinarske medicine, Beograd
dc.rightsopenAccess
dc.sourceVeterinarski glasnik
dc.subjectexperimental animalen
dc.subjectwelfareen
dc.subjectprotectionen
dc.subject3Rs ruleen
dc.subjectfive freedomsen
dc.subjectSolna principlesen
dc.subjectogledne životinjesr
dc.subjectdobrobitsr
dc.subjectzaštitasr
dc.subject3R pravilosr
dc.subjectpet slobodasr
dc.subjectSolna principisr
dc.titleBasic principles of experimental animals welfare protectionen
dc.titleOsnovni principi zaštite dobrobiti oglednih životinjasr
dc.typearticle
dc.rights.licenseBY
dcterms.abstractВучинић, Маријана; Основни принципи заштите добробити огледних животиња; Основни принципи заштите добробити огледних животиња;
dc.citation.volume61
dc.citation.issue3-4
dc.citation.spage173
dc.citation.epage181
dc.citation.other61(3-4): 173-181
dc.identifier.doi10.2298/VETGL0704173V
dc.identifier.fulltexthttp://veterinar.vet.bg.ac.rs/bitstream/id/1065/501.pdf
dc.identifier.rcubconv_172
dc.type.versionpublishedVersion


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