Genetic diversity and structure of the West Balkan Pramenka sheep types as revealed by microsatellite and mitochondrial DNA analysis
Authorized Users Only
2008
Authors
Cinkulov, M.Popovski, Z.
Porcu, K.
Tanaskovska, B.
Hodzić, A.
Bytyqi, H.
Mehmeti, H.
Margeta, V.
Đedović, R.
Hoda, A.
Trailović, Ružica
Brka, M.
Marković, B.
Važić, Božo
Vegara, Mensur
Olsaker, I.
Kantanen, J.
Article (Published version)
Metadata
Show full item recordAbstract
Several different phenotypes of the native Pramenka sheep have been developed in the Balkan region for different environmental and socio-cultural conditions. Animals from seven West Balkan Pramenka sheep types were analysed for 15 microsatellite markers and for mitochondrial DNA (mtDNA) and the results were used to assess genetic variation within and among the types and to infer the genetic population structure of the Pramenka sheep. Mean expected heterozygosity and allelic richness over the microsatellite loci and sheep types were 0.78 and 7.9, respectively. A Bayesian statistical method for estimating hidden genetic structure suggested that a core of the largest panmictic population was formed by Serbian, Kosovan, Bosnian, Montenegrin and Albanian types, while Croatian and Macedonian types comprised two other main populations, respectively. Mitochondrial DNA analysis revealed two mtDNA haplogroups in the Pramenka sheep, B and A, with a frequency of 93.7% and 6.3%, respectively. A tot...al of 60 mtDNA haplotypes were found in 64 animals sequenced, and the mean nucleotide and haplotypic diversities over the types were 0.013 and 0.945, respectively. Molecular analysis suggests that the West Balkan Pramenka sheep types have their origins in two distinct maternal lineages of domestic sheep and different Pramenka phenotypes tend to form few panmictic populations. The Pramenka sheep represents a valuable resource of genetic diversity in sheep.
Keywords:
Animal genetic resources / DNA marker / genetic variation / Pramenka sheepSource:
Journal of Animal Breeding and Genetics, 2008, 125, 6, 417-426Publisher:
- Wiley-Blackwell, Malden
Funding / projects:
- Norwegian University of Life Sciences
- Norwegian Ministry of Foreign Affairs
DOI: 10.1111/j.1439-0388.2008.00742.x
ISSN: 0931-2668
PubMed: 19134078
WoS: 000261063900009
Scopus: 2-s2.0-55949105553
Collections
Institution/Community
Fakultet veterinarske medicineTY - JOUR AU - Cinkulov, M. AU - Popovski, Z. AU - Porcu, K. AU - Tanaskovska, B. AU - Hodzić, A. AU - Bytyqi, H. AU - Mehmeti, H. AU - Margeta, V. AU - Đedović, R. AU - Hoda, A. AU - Trailović, Ružica AU - Brka, M. AU - Marković, B. AU - Važić, Božo AU - Vegara, Mensur AU - Olsaker, I. AU - Kantanen, J. PY - 2008 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/538 AB - Several different phenotypes of the native Pramenka sheep have been developed in the Balkan region for different environmental and socio-cultural conditions. Animals from seven West Balkan Pramenka sheep types were analysed for 15 microsatellite markers and for mitochondrial DNA (mtDNA) and the results were used to assess genetic variation within and among the types and to infer the genetic population structure of the Pramenka sheep. Mean expected heterozygosity and allelic richness over the microsatellite loci and sheep types were 0.78 and 7.9, respectively. A Bayesian statistical method for estimating hidden genetic structure suggested that a core of the largest panmictic population was formed by Serbian, Kosovan, Bosnian, Montenegrin and Albanian types, while Croatian and Macedonian types comprised two other main populations, respectively. Mitochondrial DNA analysis revealed two mtDNA haplogroups in the Pramenka sheep, B and A, with a frequency of 93.7% and 6.3%, respectively. A total of 60 mtDNA haplotypes were found in 64 animals sequenced, and the mean nucleotide and haplotypic diversities over the types were 0.013 and 0.945, respectively. Molecular analysis suggests that the West Balkan Pramenka sheep types have their origins in two distinct maternal lineages of domestic sheep and different Pramenka phenotypes tend to form few panmictic populations. The Pramenka sheep represents a valuable resource of genetic diversity in sheep. PB - Wiley-Blackwell, Malden T2 - Journal of Animal Breeding and Genetics T1 - Genetic diversity and structure of the West Balkan Pramenka sheep types as revealed by microsatellite and mitochondrial DNA analysis VL - 125 IS - 6 SP - 417 EP - 426 DO - 10.1111/j.1439-0388.2008.00742.x ER -
@article{ author = "Cinkulov, M. and Popovski, Z. and Porcu, K. and Tanaskovska, B. and Hodzić, A. and Bytyqi, H. and Mehmeti, H. and Margeta, V. and Đedović, R. and Hoda, A. and Trailović, Ružica and Brka, M. and Marković, B. and Važić, Božo and Vegara, Mensur and Olsaker, I. and Kantanen, J.", year = "2008", abstract = "Several different phenotypes of the native Pramenka sheep have been developed in the Balkan region for different environmental and socio-cultural conditions. Animals from seven West Balkan Pramenka sheep types were analysed for 15 microsatellite markers and for mitochondrial DNA (mtDNA) and the results were used to assess genetic variation within and among the types and to infer the genetic population structure of the Pramenka sheep. Mean expected heterozygosity and allelic richness over the microsatellite loci and sheep types were 0.78 and 7.9, respectively. A Bayesian statistical method for estimating hidden genetic structure suggested that a core of the largest panmictic population was formed by Serbian, Kosovan, Bosnian, Montenegrin and Albanian types, while Croatian and Macedonian types comprised two other main populations, respectively. Mitochondrial DNA analysis revealed two mtDNA haplogroups in the Pramenka sheep, B and A, with a frequency of 93.7% and 6.3%, respectively. A total of 60 mtDNA haplotypes were found in 64 animals sequenced, and the mean nucleotide and haplotypic diversities over the types were 0.013 and 0.945, respectively. Molecular analysis suggests that the West Balkan Pramenka sheep types have their origins in two distinct maternal lineages of domestic sheep and different Pramenka phenotypes tend to form few panmictic populations. The Pramenka sheep represents a valuable resource of genetic diversity in sheep.", publisher = "Wiley-Blackwell, Malden", journal = "Journal of Animal Breeding and Genetics", title = "Genetic diversity and structure of the West Balkan Pramenka sheep types as revealed by microsatellite and mitochondrial DNA analysis", volume = "125", number = "6", pages = "417-426", doi = "10.1111/j.1439-0388.2008.00742.x" }
Cinkulov, M., Popovski, Z., Porcu, K., Tanaskovska, B., Hodzić, A., Bytyqi, H., Mehmeti, H., Margeta, V., Đedović, R., Hoda, A., Trailović, R., Brka, M., Marković, B., Važić, B., Vegara, M., Olsaker, I.,& Kantanen, J.. (2008). Genetic diversity and structure of the West Balkan Pramenka sheep types as revealed by microsatellite and mitochondrial DNA analysis. in Journal of Animal Breeding and Genetics Wiley-Blackwell, Malden., 125(6), 417-426. https://doi.org/10.1111/j.1439-0388.2008.00742.x
Cinkulov M, Popovski Z, Porcu K, Tanaskovska B, Hodzić A, Bytyqi H, Mehmeti H, Margeta V, Đedović R, Hoda A, Trailović R, Brka M, Marković B, Važić B, Vegara M, Olsaker I, Kantanen J. Genetic diversity and structure of the West Balkan Pramenka sheep types as revealed by microsatellite and mitochondrial DNA analysis. in Journal of Animal Breeding and Genetics. 2008;125(6):417-426. doi:10.1111/j.1439-0388.2008.00742.x .
Cinkulov, M., Popovski, Z., Porcu, K., Tanaskovska, B., Hodzić, A., Bytyqi, H., Mehmeti, H., Margeta, V., Đedović, R., Hoda, A., Trailović, Ružica, Brka, M., Marković, B., Važić, Božo, Vegara, Mensur, Olsaker, I., Kantanen, J., "Genetic diversity and structure of the West Balkan Pramenka sheep types as revealed by microsatellite and mitochondrial DNA analysis" in Journal of Animal Breeding and Genetics, 125, no. 6 (2008):417-426, https://doi.org/10.1111/j.1439-0388.2008.00742.x . .