Histopathological evaluation of most frequent liver diseases in cats
Histopatološka procena najčešćih oboljenja jetre kod mačaka
Апстракт
Histological analysis was performed on the liver of 27 cats of different breeds, age and sex, autopsied at the Department of Pathological Morphology of the Faculty of Veterinary Medicine of the University of Belgrade, and findings showed lymphoplasmocytic cholangiohepatitis, different degrees of fibrosis, passive hyperemia, fatty changes, cholestase, and neoplasms. The mentioned entities occurred very rarely as individual morphological manifestations, because the liver has different functions so that one morphological change often causes others to follow. Thus, for example, fibrosis was often followed by intrahepatic cholestase. Histopathological evaluation of liver disease is important not only in the autopsied samples, but also in diagnostics of liver diseases, in samples obtained by biopsy, which is important for making a precise diagnosis. The interpretation of the established histological changes in the liver requires close cooperation between clinicians and pathologists, because ...the final diagnosis is made on the grounds of morphological, biochemical and clinical findings.
Histološkom analizom jetre kod 27 mačaka različite rase, pola i starosti, obdukovanih na Katedri za patološku morfologiju Fakulteta veterinarske medicine Univerziteta u Beogradu, ustanovljeni su limfoplazmocitni holangiohepatitis, fibroza različitog stepena, pasivna hiperemija, masna promena, holestaza i neoplazme. Navedeni entiteti su se vrlo retko javljali kao pojedinačne morfološke manifestacije, pošto jetra ima različite funkcije, pa jedna morfološka promena često za sobom povlači i druge. Tako je, na primer, fibroza bila često praćena intrahepatič nom holestazom. Histopatološka procena oboljenja jetre ima značaja ne samo na uzorcima sa obdukcije, već i kod dijagnostike oboljenja jetre, na uzorcima dobijenim biopsijom, što je značajno za postavljanje decidne dijagnoze. Za tumačenje ustanovljenih histoloških promena u jetri potrebna je tesna saradnja između kliničara i patologa, jer se konačna dijagnoza postavlja na osnovu morfoloških, biohemijskih i kliničkih nalaza.
Кључне речи:
cat / liver / morphological changes / histopathological evaluation / mačka / jetra / morfološke promene / histopatološka procenaИзвор:
Veterinarski Glasnik, 2009, 63, 1-2, 103-112Издавач:
- Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
Финансирање / пројекти:
- Дифузни систем звездастих (stellata) ћелија и њихова улога у оштећењу ткива, репарацији и неопластичним процесима код сисара (RS-MESTD-MPN2006-2010-156010)
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Kureljušić, Branislav AU - Marinković, Darko AU - Obadović, Jelena AU - Đorđević, Milena AU - Kukolj, Vladimir PY - 2009 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/584 AB - Histological analysis was performed on the liver of 27 cats of different breeds, age and sex, autopsied at the Department of Pathological Morphology of the Faculty of Veterinary Medicine of the University of Belgrade, and findings showed lymphoplasmocytic cholangiohepatitis, different degrees of fibrosis, passive hyperemia, fatty changes, cholestase, and neoplasms. The mentioned entities occurred very rarely as individual morphological manifestations, because the liver has different functions so that one morphological change often causes others to follow. Thus, for example, fibrosis was often followed by intrahepatic cholestase. Histopathological evaluation of liver disease is important not only in the autopsied samples, but also in diagnostics of liver diseases, in samples obtained by biopsy, which is important for making a precise diagnosis. The interpretation of the established histological changes in the liver requires close cooperation between clinicians and pathologists, because the final diagnosis is made on the grounds of morphological, biochemical and clinical findings. AB - Histološkom analizom jetre kod 27 mačaka različite rase, pola i starosti, obdukovanih na Katedri za patološku morfologiju Fakulteta veterinarske medicine Univerziteta u Beogradu, ustanovljeni su limfoplazmocitni holangiohepatitis, fibroza različitog stepena, pasivna hiperemija, masna promena, holestaza i neoplazme. Navedeni entiteti su se vrlo retko javljali kao pojedinačne morfološke manifestacije, pošto jetra ima različite funkcije, pa jedna morfološka promena često za sobom povlači i druge. Tako je, na primer, fibroza bila često praćena intrahepatič nom holestazom. Histopatološka procena oboljenja jetre ima značaja ne samo na uzorcima sa obdukcije, već i kod dijagnostike oboljenja jetre, na uzorcima dobijenim biopsijom, što je značajno za postavljanje decidne dijagnoze. Za tumačenje ustanovljenih histoloških promena u jetri potrebna je tesna saradnja između kliničara i patologa, jer se konačna dijagnoza postavlja na osnovu morfoloških, biohemijskih i kliničkih nalaza. PB - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd T2 - Veterinarski Glasnik T1 - Histopathological evaluation of most frequent liver diseases in cats T1 - Histopatološka procena najčešćih oboljenja jetre kod mačaka VL - 63 IS - 1-2 SP - 103 EP - 112 DO - 10.2298/VETGL0902103K ER -
@article{ author = "Kureljušić, Branislav and Marinković, Darko and Obadović, Jelena and Đorđević, Milena and Kukolj, Vladimir", year = "2009", abstract = "Histological analysis was performed on the liver of 27 cats of different breeds, age and sex, autopsied at the Department of Pathological Morphology of the Faculty of Veterinary Medicine of the University of Belgrade, and findings showed lymphoplasmocytic cholangiohepatitis, different degrees of fibrosis, passive hyperemia, fatty changes, cholestase, and neoplasms. The mentioned entities occurred very rarely as individual morphological manifestations, because the liver has different functions so that one morphological change often causes others to follow. Thus, for example, fibrosis was often followed by intrahepatic cholestase. Histopathological evaluation of liver disease is important not only in the autopsied samples, but also in diagnostics of liver diseases, in samples obtained by biopsy, which is important for making a precise diagnosis. The interpretation of the established histological changes in the liver requires close cooperation between clinicians and pathologists, because the final diagnosis is made on the grounds of morphological, biochemical and clinical findings., Histološkom analizom jetre kod 27 mačaka različite rase, pola i starosti, obdukovanih na Katedri za patološku morfologiju Fakulteta veterinarske medicine Univerziteta u Beogradu, ustanovljeni su limfoplazmocitni holangiohepatitis, fibroza različitog stepena, pasivna hiperemija, masna promena, holestaza i neoplazme. Navedeni entiteti su se vrlo retko javljali kao pojedinačne morfološke manifestacije, pošto jetra ima različite funkcije, pa jedna morfološka promena često za sobom povlači i druge. Tako je, na primer, fibroza bila često praćena intrahepatič nom holestazom. Histopatološka procena oboljenja jetre ima značaja ne samo na uzorcima sa obdukcije, već i kod dijagnostike oboljenja jetre, na uzorcima dobijenim biopsijom, što je značajno za postavljanje decidne dijagnoze. Za tumačenje ustanovljenih histoloških promena u jetri potrebna je tesna saradnja između kliničara i patologa, jer se konačna dijagnoza postavlja na osnovu morfoloških, biohemijskih i kliničkih nalaza.", publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd", journal = "Veterinarski Glasnik", title = "Histopathological evaluation of most frequent liver diseases in cats, Histopatološka procena najčešćih oboljenja jetre kod mačaka", volume = "63", number = "1-2", pages = "103-112", doi = "10.2298/VETGL0902103K" }
Kureljušić, B., Marinković, D., Obadović, J., Đorđević, M.,& Kukolj, V.. (2009). Histopathological evaluation of most frequent liver diseases in cats. in Veterinarski Glasnik Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 63(1-2), 103-112. https://doi.org/10.2298/VETGL0902103K
Kureljušić B, Marinković D, Obadović J, Đorđević M, Kukolj V. Histopathological evaluation of most frequent liver diseases in cats. in Veterinarski Glasnik. 2009;63(1-2):103-112. doi:10.2298/VETGL0902103K .
Kureljušić, Branislav, Marinković, Darko, Obadović, Jelena, Đorđević, Milena, Kukolj, Vladimir, "Histopathological evaluation of most frequent liver diseases in cats" in Veterinarski Glasnik, 63, no. 1-2 (2009):103-112, https://doi.org/10.2298/VETGL0902103K . .