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dc.creatorAtrrog, Abubaker A. B.
dc.creatorNatić, Maja
dc.creatorTosti, Tomislav
dc.creatorMilojković-Opsenica, Dušanka
dc.creatorĐorđević, Iris
dc.creatorTešević, Vele
dc.creatorJadranin, Milka
dc.creatorMilosavljević, Slobodan M.
dc.creatorLazić, Milan
dc.creatorRadulović, Siniša
dc.creatorTešić, Živoslav
dc.date.accessioned2020-06-03T13:14:58Z
dc.date.available2020-06-03T13:14:58Z
dc.date.issued2009
dc.identifier.issn0269-3879
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/619
dc.description.abstractIn this study 10 guaianolide-type sesquiterpene gamma-lactones named amphoricarpolides, isolated from the aerial parts of two endemic subspecies of Amphoricarpos neumayeri (ssp. neumayeri and ssp. murbeckii Bosnjak), were investigated by means of reversed-phase thin-layer chromatography. Methanol-water and tetrahydrofuran-water binary mixtures were used as mobile phase in order to determine lipophilicity parameters R-M(0) and C-0. Some of the investigated compounds were screened for their cytotoxic activity against HeLa and B16 cells. Chromatographically obtained lipophilicity parameters were correlated with calculated logP values and IC50 values. Principal component analysis identified the dominant pattern in the chromatographically obtained data. Copyrighten
dc.publisherWiley, Hoboken
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/142062/RS//
dc.rightsrestrictedAccess
dc.sourceBiomedical Chromatography
dc.subjectguaianolidesen
dc.subjectreversed-phase thin-layer chromatographyen
dc.subjectlipophilicityen
dc.subjectstructure-activity relationshipen
dc.subjectPCAen
dc.titleLipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegroen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЛазић, Милан; Милојковић-Опсеница, Душанка; Тешевић, Веле; Милосављевић, Слободан М.; Тости, Томислав; Радуловић, Синиша; Тешић, Живослав; Ђорђевић, Ирис; Јадранин, Милка; Aтррог, Aбубакер A. Б.; Натић, Маја;
dc.citation.volume23
dc.citation.issue3
dc.citation.spage250
dc.citation.epage256
dc.citation.other23(3): 250-256
dc.citation.rankM22
dc.identifier.wos000263776700003
dc.identifier.doi10.1002/bmc.1091
dc.identifier.pmid18816478
dc.identifier.scopus2-s2.0-65249100236
dc.identifier.rcubconv_1634
dc.type.versionpublishedVersion


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