In vitro cytogenetic analysis of the effects of oxytocin on human peripheral blood lymphocytes
Samo za registrovane korisnike
1996
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The purpose of this study was to determine possible genotoxic and cytotoxic (or mitogenic) effects of high concentrations of oxytocin, active component of Syntocinon(R) in cultures of human peripheral blood lymphocytes. Two test systems were used: (1) analysis of numerical and structural chromosome aberrations, and (2) the in vitro sister chromatid exchange (SCE) test. On the basis of the results obtained it can be concluded that oxytocin does not express any genotoxical properties. Furthermore, the mitotic index did not change significantly.
Ključne reči:
oxytocin / genotoxicity / sister chromatid exchange / chromosome aberration / mitotic indexIzvor:
Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 1996, 356, 2, 265-268Izdavač:
- Elsevier, Amsterdam
DOI: 10.1016/0027-5107(96)00071-1
ISSN: 0027-5107
PubMed: 8841495
WoS: A1996VJ55900019
Scopus: 2-s2.0-0030599150
Kolekcije
Institucija/grupa
Fakultet veterinarske medicineTY - JOUR AU - Đelić, Ninoslav AU - Soldatović, Bogosav AU - Anđelković, M AU - Cvetković, D PY - 1996 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/71 AB - The purpose of this study was to determine possible genotoxic and cytotoxic (or mitogenic) effects of high concentrations of oxytocin, active component of Syntocinon(R) in cultures of human peripheral blood lymphocytes. Two test systems were used: (1) analysis of numerical and structural chromosome aberrations, and (2) the in vitro sister chromatid exchange (SCE) test. On the basis of the results obtained it can be concluded that oxytocin does not express any genotoxical properties. Furthermore, the mitotic index did not change significantly. PB - Elsevier, Amsterdam T2 - Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis T1 - In vitro cytogenetic analysis of the effects of oxytocin on human peripheral blood lymphocytes VL - 356 IS - 2 SP - 265 EP - 268 DO - 10.1016/0027-5107(96)00071-1 ER -
@article{ author = "Đelić, Ninoslav and Soldatović, Bogosav and Anđelković, M and Cvetković, D", year = "1996", abstract = "The purpose of this study was to determine possible genotoxic and cytotoxic (or mitogenic) effects of high concentrations of oxytocin, active component of Syntocinon(R) in cultures of human peripheral blood lymphocytes. Two test systems were used: (1) analysis of numerical and structural chromosome aberrations, and (2) the in vitro sister chromatid exchange (SCE) test. On the basis of the results obtained it can be concluded that oxytocin does not express any genotoxical properties. Furthermore, the mitotic index did not change significantly.", publisher = "Elsevier, Amsterdam", journal = "Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis", title = "In vitro cytogenetic analysis of the effects of oxytocin on human peripheral blood lymphocytes", volume = "356", number = "2", pages = "265-268", doi = "10.1016/0027-5107(96)00071-1" }
Đelić, N., Soldatović, B., Anđelković, M.,& Cvetković, D.. (1996). In vitro cytogenetic analysis of the effects of oxytocin on human peripheral blood lymphocytes. in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis Elsevier, Amsterdam., 356(2), 265-268. https://doi.org/10.1016/0027-5107(96)00071-1
Đelić N, Soldatović B, Anđelković M, Cvetković D. In vitro cytogenetic analysis of the effects of oxytocin on human peripheral blood lymphocytes. in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis. 1996;356(2):265-268. doi:10.1016/0027-5107(96)00071-1 .
Đelić, Ninoslav, Soldatović, Bogosav, Anđelković, M, Cvetković, D, "In vitro cytogenetic analysis of the effects of oxytocin on human peripheral blood lymphocytes" in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 356, no. 2 (1996):265-268, https://doi.org/10.1016/0027-5107(96)00071-1 . .