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Komparativno ispitivanje efikasnosti eugenola i benzil-benzoata u terapiji šuge ovaca

dc.creatorJezdimirović, Milanka
dc.creatorAleksić, Nevenka
dc.creatorRadojičić, Biljana
dc.date.accessioned2020-06-03T13:23:48Z
dc.date.available2020-06-03T13:23:48Z
dc.date.issued2010
dc.identifier.issn0350-2457
dc.identifier.urihttps://vet-erinar.vet.bg.ac.rs/handle/123456789/742
dc.description.abstractThe acaricide efficacy, tolerance and safety of eugenol (10 and 20 %) in the treatment of sarcoptic mange in sheep have been investigated. The results were compared with those corresponding for benzyl benzoate (25 %), which was applied to sheep in the same way. The treatment was applied on sheep three times in one-week intervals. Skin scrapings were sampled seven days after each treatment, as well as twenty-eight days following the third one. The changes on the skin were quantified and the mean recovery response (MRR) was calculated. The clinical efficacy was assessed according to the MRR and the number of mites in the samples. Following the first treatment 10%eugenol was not significantly less efficacious in comparison with the higher concentration. Having been applied twice 20% eugenol was significantly more efficacious when compared to the lower concentration, which remained the same seven and twenty-eight days after the third application. The efficacy of 10% eugenol in the therapy of mange was significantly higher in comparison with benzyl benzoate following one, two or three administrations. The efficacy of benzyl benzoate four weeks after the third treatment was still significantly lower in comparison with 10% eugenol. The efficacy of 20% eugenol was significantly higher in comparison with its lower concentration as well as that of benzyl benzoate, following the second, and seven and twenty-eight days after the third one. No signs of local or systemic intolerance were observed in sheep treated with either 10 or 20% eugenol, or 25 % benzyl benzoate. .en
dc.description.abstractIspitivana je akaricidna efikasnost, podnošljivost i bezbednost eugenola (10 i 20%) u lečenju sarkoptes-šuge ovaca. Rezultati ispitivanja upoređivani su sa odgovarajućim podacima dobijenim posle primene benzil-benzoata (25 %) primenjivanog na isti način u lečenju šuge ovaca. Tretiranje ovaca je obavljeno tri puta u vremenskom intervalu od po sedam dana. U cilju provere efikasnosti primenjenih lekova uzorci kože su uzimani 7 dana posle svakog tretmana, kao i 28 dana posle trećeg tretmana. Promene na koži izazvane šugarcima su kvantifikovane, na osnovu čega je određivan klinički skor (mean recovery response, MRR). Klinička efikasnost lekova procenjivana je na osnovu povlačenja kliničkih simptoma šuge kao i na osnovu broja prisutnih šugaraca u uzorcima strugotine kože. Eugenol u koncentraciji od 10 % posle prvog tretmana nije imao značajno manju efikasnost u odnosu na veću koncentraciju. Posle drugog tretmana efikasnost eugenola od 20 % bila je statistički značajno veća u odnosu na nižu koncentraciju, što je dokazano i 7 i 28 dana nakon trećeg tretmana. Eugenol je u koncentraciji od 10 % imao statistički značajno veću efikasnost od benzilbenzoata u terapiji šuge ovaca, kako posle prvog, tako i posle drugog i trećeg tretmana. Proverom efikasnosti benzil-benzoata posle 4 nedelje od trećeg tretmana dokazano je da je ona i dalje značajno manja u odnosu na eugenol u koncentraciji od 10 %. Efikasnost eugenola u koncentraciji od 20 % u lečenju sarkoptes-šuge ovaca bila je statistički značajno veća u odnosu na efikasnost eugenola u koncentraciji od 10 %, kao i benzil-benzoat, i posle drugog tretmana i posle 7 i 28 dana posle trećeg tretmana. Tokom trokratne primene eugenola u koncentraciji od 10 i 20%i benzil-benzoata u koncentraciji od 25% nisu zapaženi bilo kakvi znaci lokalne i sistemske nepodnošljivosti kod tretiranih ovaca.sr
dc.publisherUniverzitet u Beogradu - Fakultet veterinarske medicine, Beograd
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceVeterinarski Glasnik
dc.subjecteugenolen
dc.subjectbenzyl benzoateen
dc.subjectmangeen
dc.subjectSarcoptes scabieien
dc.subjectsheepen
dc.subjecteugenolsr
dc.subjectbenzil-benzoatsr
dc.subjectšugasr
dc.subjectSarcoptes scabieisr
dc.subjectovcesr
dc.titleInvestigation of comparative efficacy of eugenol and benzyl benzoate in therapy of sheep mangeen
dc.titleKomparativno ispitivanje efikasnosti eugenola i benzil-benzoata u terapiji šuge ovacasr
dc.typearticle
dc.rights.licenseBY
dcterms.abstractРадојичић, Биљана; Јездимировић, Миланка; Aлексић, Невенка; Компаративно испитивање ефикасности еугенола и бензил-бензоата у терапији шуге оваца; Компаративно испитивање ефикасности еугенола и бензил-бензоата у терапији шуге оваца;
dc.citation.volume64
dc.citation.issue3-4
dc.citation.spage177
dc.citation.epage185
dc.citation.other64(3-4): 177-185
dc.citation.rankM51
dc.identifier.doi10.2298/VETGL1004177J
dc.identifier.fulltexthttps://vet-erinar.vet.bg.ac.rs/bitstream/id/1284/741.pdf
dc.type.versionpublishedVersion


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