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dc.creatorPopović, Tamara
dc.creatorBorozan, Sunčica
dc.creatorArsić, Aleksandra
dc.creatorDebeljak-Martačić, Jasmina
dc.creatorVucić, Vesna
dc.creatorde Luka, Silvio
dc.creatorMilovanović, Ivan
dc.creatorTrbović, Aleksandar
dc.creatorGlibetić, Maria
dc.date.accessioned2020-06-03T13:27:48Z
dc.date.available2020-06-03T13:27:48Z
dc.date.issued2011
dc.identifier.issn0011-1643
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/799
dc.description.abstractThe effects of fish oil supplementation in Wistar rats are focused on cardiovascular, endocrine, metabolic and antioxidant status changes. We determined plasma and liver phospholipid fatty acids (FAs) status and plasma lipid concentrations in aged Wistar rats. Our results showed differences in plasma and liver FAs profiles as well as plasma chlolesterol (CHOL), triglicerides (TG), high density lipoproteins (HDL), low density lipoproteins (LDL), CHOL/HDL ratio (risk factor for atherosclerosis) and LDL/HDL ratio (risk for cardiovascular diseases) between treated and control group of animals. In fish oil treated group there were statistically significant changes in FAs profile in increasing linoleic acid (LA), dihomo-gamma linoleic acid, eicopentanoic acid (EPA) and docosapentaenoic acid (DPA) and decreasing in arachidonic acid (AA) concentration. Also, liver phospholipids FAs results showed increasing concentrations of vascenic acid, LA, EPA, and DPA and decreasing concentration of AA after supplementation of fish oil compared to control group. However, concentrations of CHOL, LDL and non HDL concentrations decreased while HDL increased in fish oil group. CHOL/HDL, LDL/HDL ratios decreased. These findings suggest that long term treatment of fish oil in aged Wistar rats can be beneficial in decreasing LDL, and decreasing risk factors for developing atherosclerosis and cardiovascular diseases. (doi: 10.5562/cca1751)en
dc.publisherCroatian Chemical Soc, Zagreb
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41030/RS//
dc.rightsopenAccess
dc.sourceCroatica Chemica Acta
dc.subjectfish oilen
dc.subjectaged ratsen
dc.subjectfatty acidsen
dc.subjectlipid statusen
dc.titleEffects of n-3 Supplementation on Plasma and Liver Phospholipid Fatty Acids Profile in Aged Wistar Ratsen
dc.typearticle
dc.rights.licenseBY
dcterms.abstractМиловановић, Иван; Вуцић, Весна; Трбовић, Aлександар; Поповић, Тамара; Борозан, Сунчица; де Лука, Силвио; Дебељак-Мартачић, Јасмина; Aрсић, Aлександра; Глибетић, Мариа;
dc.citation.volume84
dc.citation.issue1
dc.citation.spage73
dc.citation.epage79
dc.citation.other84(1): 73-79
dc.citation.rankM23
dc.identifier.wos000292799300010
dc.identifier.doi10.5562/cca1751
dc.identifier.scopus2-s2.0-79960203892
dc.identifier.fulltexthttp://veterinar.vet.bg.ac.rs/bitstream/id/1333/798.pdf
dc.identifier.rcubconv_1783
dc.type.versionpublishedVersion


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