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dc.creatorRadovanović, Anita
dc.creatorStosicBogdanović, N
dc.creatorGledić, Dušan
dc.date.accessioned2020-06-03T12:37:17Z
dc.date.available2020-06-03T12:37:17Z
dc.date.issued1997
dc.identifier.issn0567-8315
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/85
dc.description.abstractThe effect of early hyperthyroidism on folliculogenesis in the ovary of juvenile rats was investigated. Hyperthyroidism was induced by injection of 150 μg DL-thyroxine (DL-T 4 ) to females every other day, from the 9 th to the 29 th day of life. Twenty four hours after the last injection treated females and corresponding intact animals were sacrificed, and the ovaries were examined using standard light microscopy and semithin sections. DL-T4 caused a significant decrease of pituitary and ovary mass, compared to intact animals. The population of healthy primary follicles was increased in the ovaries of treated rats. At the same time, the total number of atretic follicles, especially growing, was also significantly increased. Antral follicles without apoptotic changes were scarcely observed. Furthermore, granulosa cells displayed morphological changes characteristic for apoptosis: widened intercellular spaces, condensation of chromatin, cellular fragmentation and formation of atretic bodies.en
dc.publisherUniverzitet u Beogradu - Fakultet veterinarske medicine, Beograd
dc.rightsrestrictedAccess
dc.sourceActa veterinaria - Beograd
dc.subjectDL-thyroxineen
dc.subjecthyperthyroidismen
dc.subjectovaryen
dc.subjectjuvenile raten
dc.titleFollicular development and atresia in the ovaries of thyroxine treated juvenile ratsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractРадовановић, Aнита; СтосицБогдановић, Н; Гледић, Душан;
dc.citation.volume47
dc.citation.issue2-3
dc.citation.spage87
dc.citation.epage94
dc.citation.other47(2-3): 87-94
dc.identifier.wosA1997XJ66000001
dc.identifier.scopus2-s2.0-2842548531
dc.identifier.rcubconv_2627
dc.type.versionpublishedVersion


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