Show simple item record

dc.creatorSavić, Božidar
dc.creatorMilićević, Vesna
dc.creatorJakić-Dimić, Dobrila
dc.creatorBojkovski, Jovan
dc.creatorProdanović, Radiša
dc.creatorKureljusić, Branislav
dc.creatorPotkonjak, Aleksandar
dc.creatorSavić, Borivoje
dc.date.accessioned2020-06-03T13:34:00Z
dc.date.available2020-06-03T13:34:00Z
dc.date.issued2012
dc.identifier.issn0304-8608
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/889
dc.description.abstractPorcine circovirus type 2 (PCV2) is the main causative agent of postweaning multisystemic wasting syndrome (PMWS). To characterize and determine the genetic diversity of PCV2 in the porcine population of Serbia, nucleotide and deduced amino acid sequences of the open reading frame 2 (ORF2) of PCV2 collected from the tissues of pigs that either had died as a result of PMWS or did not exhibit disease symptoms were analyzed. Sequencing and phylogenetic analysis showed considerable diversity among PCV2 ORF2 sequences and the existence of two main PCV2 genotypes, PCV2b and PCV2a, with at least three clusters, 1A/B, 1C and 2D. In order to provide further proof that the 1C strain is circulating in the porcine population, the whole viral genome of one PCV2 isolate was sequenced. Genotyping and phylogenetic analysis using the entire viral genome sequences confirmed that there was a PMWS-associated 1C strain emerging in Serbia. Our analysis also showed that PCV2b is dominant in the porcine population, and that it is exclusively associated with PMWS occurrences in the country. These data constitute a useful basis for further epidemiological studies regarding the heterogeneity of PCV2 strains on the European continent.en
dc.publisherSpringer Wien, Wien
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31062/RS//
dc.rightsrestrictedAccess
dc.sourceArchives of Virology
dc.titleGenetic characterization and phylogenetic analysis of porcine circovirus type 2 (PCV2) in Serbiaen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЈакић-Димић, Добрила; Савић, Божидар; Бојковски, Јован; Продановић, Радиша; Савић, Боривоје; Милићевић, Весна; Курељусић, Бранислав; Поткоњак, Aлександар;
dc.citation.volume157
dc.citation.issue1
dc.citation.spage21
dc.citation.epage28
dc.citation.other157(1): 21-28
dc.citation.rankM23
dc.identifier.wos000299845800002
dc.identifier.doi10.1007/s00705-011-1130-9
dc.identifier.pmid21964944
dc.identifier.scopus2-s2.0-84855312239
dc.identifier.rcubconv_1814
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record