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Kardiovaskularni efekti vazoaktivnih supstanci u produženoj anesteziji kod pasa

dc.creatorSpasojević-Kosić, Ljubica
dc.creatorTrailović, Dragiša
dc.date.accessioned2020-06-03T13:37:41Z
dc.date.available2020-06-03T13:37:41Z
dc.date.issued2012
dc.identifier.issn1820-9955
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/943
dc.description.abstractKnowledge of the influence of anesthesia in anesthetized animals at in vivo experiments is essential in order to interpret the results of investigations properly and correctly. In this study we researched cardiovascular effects of vasoactive substances (adrenalin, noepinephrine, dimethylphenylpiperazinium, acethylholin, histamine) in prolonged anesthesia of six hours in dogs. The cardiovascular effects of vasoactive substances were evaluated by direct blood pressure measurement, ecg monitoring and urine output measurement. The dose-effect curve of systolic (SAP) and diastolic (DAP) blood pressure were obtained for each of the vasoactive substances. The differences between cardiovascular effects of vasoactive substances at the beginning and at the end of prolonged anesthesia were tested. There were statistically significant differences (p lt 0.05) in changes of blood pressure at the beginning and at the end of prolonged anesthesia only for some doses of adrenalin and histamine (1 mg/kg and 3 mg/kg). No significant changes in heart rhythms at the beginning and at the end of prolonged anesthesia were recorded. The urine output during anesthesia depended on applied vasoactive substances.en
dc.description.abstractIn vivo eksperimenti na anestetisanim životinjama zahtevaju poznavanje uticaja anestezije kako bi se rezultati eksperimenta tačno interpretirali. U ovom radu su ispitani kardiovaskularni efekti vazoaktivnih supstanci (adrenalin, noradrenalin, dimetilfenilpiperazin, acetilholin i histamin) u uslovima produžene šestočasovne anestezije kod pasa. Kardiovaskularni efekti vazoaktivnih supstanci su procenjeni direktnim merenjem arterijskog pritiska, elektrokardiografijom i merenjem diureze. Izrađene su doza-efekat krive za sistolni (SAP) i dijastolni (DAP) arterijski pritisak za sve ispitivane vazoaktivne supstance. Procenjivana je razlika u kardiovaskulanim efektima vazoaktivnih supstanci na početku i na kraju anestezije. Postojala je statistički značajna razlika (p lt 0,05) u promeni arterijskog pritiska na početku i kraju produžene anestezije samo za pojedine doze adrenalina i histamina (1 mg/kg i 3 mg/kg). Nije postojala značajna razlika u promeni srčanog ritma na početku i na kraju anestezije. Promene diureze tokom anestezije su zavisile od aplikovane vazoaktivne supstance.sr
dc.publisherNaučni institut za veterinarstvo "Novi Sad", Novi Sad
dc.rightsopenAccess
dc.sourceArhiv veterinarske medicine
dc.subjectprolonged anesthesiaen
dc.subjectdogen
dc.subjectvasoactive substancesen
dc.subjectcardiovascular effectsen
dc.subjectprodužena anestezijasr
dc.subjectpassr
dc.subjectvazoaktivne supstancesr
dc.subjectkardiovaskularni efektisr
dc.titleCardiovascular effects of vasoactive substances in prolonged anesthesia in dogsen
dc.titleKardiovaskularni efekti vazoaktivnih supstanci u produženoj anesteziji kod pasasr
dc.typearticle
dc.rights.licenseARR
dcterms.abstractТраиловић, Драгиша; Спасојевић-Косић, Љубица; Кардиоваскуларни ефекти вазоактивних супстанци у продуженој анестезији код паса; Кардиоваскуларни ефекти вазоактивних супстанци у продуженој анестезији код паса;
dc.citation.volume5
dc.citation.issue1
dc.citation.spage31
dc.citation.epage42
dc.citation.other5(1): 31-42
dc.citation.rankM51
dc.identifier.rcubconv_1177
dc.type.versionpublishedVersion


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