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Antiproliferative effects of Camellia sinensis, Frangula alnus and Rosmarinus officinalis
dc.creator | Cenić-Milošević, Desanka | |
dc.creator | Tambur, Zoran | |
dc.creator | Ivančajić, S. | |
dc.creator | Bokonjić, Dubravko | |
dc.creator | Čuković, Anika | |
dc.creator | Stanojković, Tatjana | |
dc.creator | Grozdanić, Nadja | |
dc.creator | Kulišić, Zoran | |
dc.creator | Juranić, Zorica | |
dc.date.accessioned | 2020-06-03T13:39:11Z | |
dc.date.available | 2020-06-03T13:39:11Z | |
dc.date.issued | 2013 | |
dc.identifier.issn | 0354-4664 | |
dc.identifier.uri | https://vet-erinar.vet.bg.ac.rs/handle/123456789/965 | |
dc.description.abstract | The use of medicinal plants is becoming increasingly appreciated in suppressing cancer growth and cancer prevention. In this study the antiproliferative effects of the water extracts of previously obtained ethanolic dry extracts of three different medicinal plants (Camellia sinensis, Frangula alnus from two different places and Rosmarinus officinalis) using cell lines derived from human cervix adenocarcinoma (Hela cells) were investigated. The extract of Camellia sinensis exhibited significant cytotoxic effect against Hela cells (IC50 40.88 μg/ml). Screening in Hela cells revealed a moderate cytotoxic effect (IC50 80.26μg/ml) of the extract of Rosmarinus officinalis, a mild cytotoxic effect (IC50 148.05 μg/ml) of the extract of Frangula alnus (originating in Bosnia), and the extract of Frangula alnus (originating in Serbia) did not show active cytotoxicity (IC50 > 200 μg/ml). The best antiproliferative properties are those of Camellia sinensis, followed by Rosmarinus officinalis, and the least effective was Frangula alnus. As regards geographic origin, the Frangula alnus from Bosnia possessed better antiproliferative effects than Frangula alnus from Serbia. | en |
dc.publisher | Srpsko biološko društvo, Beograd, i dr. | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175011/RS// | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Archives of Biological Sciences | |
dc.subject | Antiproliferative effect | en |
dc.subject | Camellia sinensis | en |
dc.subject | Frangula alnus | en |
dc.subject | Rosmarinus officinalis | en |
dc.title | Antiproliferative effects of Camellia sinensis, Frangula alnus and Rosmarinus officinalis | en |
dc.type | article | |
dc.rights.license | BY-NC-ND | |
dcterms.abstract | Кулишић, Зоран; Ценић-Милошевић, Десанка; Станојковић, Татјана; Чуковић, Aника; Јуранић, Зорица; Грозданић, Надја; Тамбур, Зоран; Иванчајић, С.; Бокоњић, Дубравко; | |
dc.citation.volume | 65 | |
dc.citation.issue | 3 | |
dc.citation.spage | 885 | |
dc.citation.epage | 891 | |
dc.citation.other | 65(3): 885-891 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000322348800009 | |
dc.identifier.doi | 10.2298/ABS1303885M | |
dc.identifier.scopus | 2-s2.0-84882675837 | |
dc.identifier.fulltext | https://vet-erinar.vet.bg.ac.rs/bitstream/id/1479/964.pdf | |
dc.type.version | publishedVersion |