Antiproliferative effects of tanaceti partheni, hypericum perforatum and propolis on hela cells
2014
Autori
Cenić-Milošević, DesankaTambur, Zoran
Ivancajić, S.
Stanojković, Tatjana
Grozdanić, Nadja
Kulišić, Zoran
Juranić, Zorica
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Tanaceti partheni, Hypericum perforatum and propolis have been widely used for centuries and are well-documented medicinal plants and natural product. In this study, we investigated the antiproliferative effects of water extracts of ethanolic dry extracts of two different medicinal plants (Tanaceti partheni and Hypericum perforatum) and propolis on HeLa cells. The Tanaceti partheni extract exhibited mild cytotoxic activity The IC50 was 153.71 mu g/mL. The extract of Hypericum perforatum did not show active cytotoxic activity against HeLa cells (IC50 >200 [mu g/mL). Regarding the antiproliferative effects of Hypericum perforatum, our results are not in correlation with the results of other authors, probably because different Hypericum species and different human cancer cell lines were used. The extract of propolis did not show active cytotoxic activity against HeLa cells (IC50 +/- 1.08 0.01 mg/mL). The weak antiproliferative effect of propolis on HeLa cells is either due to the use of a... low concentration of propolis extracted in weakly polar solvents, or the use of propolis collected in the autumn.
Ključne reči:
Antiproliferative effect / Tanaceti partheni / Hypericum perforatum / propolisIzvor:
Archives of Biological Sciences, 2014, 66, 2, 705-712Izdavač:
- Srpsko biološko društvo, Beograd
Finansiranje / projekti:
- Ministry of Education and Science of Republic of Serbia [34021]
- Modifikatori biološkog odgovora u fiziološkim i patološkim stanjima (RS-MESTD-Basic Research (BR or ON)-175011)
DOI: 10.2298/ABS1402705M
ISSN: 0354-4664
WoS: 000342265800029
Scopus: 2-s2.0-84903955416
Kolekcije
Institucija/grupa
Fakultet veterinarske medicineTY - JOUR AU - Cenić-Milošević, Desanka AU - Tambur, Zoran AU - Ivancajić, S. AU - Stanojković, Tatjana AU - Grozdanić, Nadja AU - Kulišić, Zoran AU - Juranić, Zorica PY - 2014 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1084 AB - Tanaceti partheni, Hypericum perforatum and propolis have been widely used for centuries and are well-documented medicinal plants and natural product. In this study, we investigated the antiproliferative effects of water extracts of ethanolic dry extracts of two different medicinal plants (Tanaceti partheni and Hypericum perforatum) and propolis on HeLa cells. The Tanaceti partheni extract exhibited mild cytotoxic activity The IC50 was 153.71 mu g/mL. The extract of Hypericum perforatum did not show active cytotoxic activity against HeLa cells (IC50 >200 [mu g/mL). Regarding the antiproliferative effects of Hypericum perforatum, our results are not in correlation with the results of other authors, probably because different Hypericum species and different human cancer cell lines were used. The extract of propolis did not show active cytotoxic activity against HeLa cells (IC50 +/- 1.08 0.01 mg/mL). The weak antiproliferative effect of propolis on HeLa cells is either due to the use of a low concentration of propolis extracted in weakly polar solvents, or the use of propolis collected in the autumn. PB - Srpsko biološko društvo, Beograd T2 - Archives of Biological Sciences T1 - Antiproliferative effects of tanaceti partheni, hypericum perforatum and propolis on hela cells VL - 66 IS - 2 SP - 705 EP - 712 DO - 10.2298/ABS1402705M ER -
@article{ author = "Cenić-Milošević, Desanka and Tambur, Zoran and Ivancajić, S. and Stanojković, Tatjana and Grozdanić, Nadja and Kulišić, Zoran and Juranić, Zorica", year = "2014", abstract = "Tanaceti partheni, Hypericum perforatum and propolis have been widely used for centuries and are well-documented medicinal plants and natural product. In this study, we investigated the antiproliferative effects of water extracts of ethanolic dry extracts of two different medicinal plants (Tanaceti partheni and Hypericum perforatum) and propolis on HeLa cells. The Tanaceti partheni extract exhibited mild cytotoxic activity The IC50 was 153.71 mu g/mL. The extract of Hypericum perforatum did not show active cytotoxic activity against HeLa cells (IC50 >200 [mu g/mL). Regarding the antiproliferative effects of Hypericum perforatum, our results are not in correlation with the results of other authors, probably because different Hypericum species and different human cancer cell lines were used. The extract of propolis did not show active cytotoxic activity against HeLa cells (IC50 +/- 1.08 0.01 mg/mL). The weak antiproliferative effect of propolis on HeLa cells is either due to the use of a low concentration of propolis extracted in weakly polar solvents, or the use of propolis collected in the autumn.", publisher = "Srpsko biološko društvo, Beograd", journal = "Archives of Biological Sciences", title = "Antiproliferative effects of tanaceti partheni, hypericum perforatum and propolis on hela cells", volume = "66", number = "2", pages = "705-712", doi = "10.2298/ABS1402705M" }
Cenić-Milošević, D., Tambur, Z., Ivancajić, S., Stanojković, T., Grozdanić, N., Kulišić, Z.,& Juranić, Z.. (2014). Antiproliferative effects of tanaceti partheni, hypericum perforatum and propolis on hela cells. in Archives of Biological Sciences Srpsko biološko društvo, Beograd., 66(2), 705-712. https://doi.org/10.2298/ABS1402705M
Cenić-Milošević D, Tambur Z, Ivancajić S, Stanojković T, Grozdanić N, Kulišić Z, Juranić Z. Antiproliferative effects of tanaceti partheni, hypericum perforatum and propolis on hela cells. in Archives of Biological Sciences. 2014;66(2):705-712. doi:10.2298/ABS1402705M .
Cenić-Milošević, Desanka, Tambur, Zoran, Ivancajić, S., Stanojković, Tatjana, Grozdanić, Nadja, Kulišić, Zoran, Juranić, Zorica, "Antiproliferative effects of tanaceti partheni, hypericum perforatum and propolis on hela cells" in Archives of Biological Sciences, 66, no. 2 (2014):705-712, https://doi.org/10.2298/ABS1402705M . .