Endocrine and metabolic status of dairy cows during transition period
Authorized Users Only
2014
Authors
Đoković, RadojicaCincović, Marko
Kurcubić, Vladimir
Petrović, Milun D.
Lalović, Miroslav
Jasović, Boban
Stanimirović, Zoran
Article (Published version)
Metadata
Show full item recordAbstract
The objective of this study was to determine blood levels of cortisol, insulin, triiodothyronine (T3), thyroxine (T4), glucose, non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), triglycerides (TG) and total cholesterol in dairy Holstein cows (n = 40) during the transition period. The test cows were classified into four groups: Group A (n = 10), clinically healthy late-pregnant cows from day 20 to day 10 before calving. Group B (n = 10), clinically healthy late-pregnant cows from day 10 to day 1 before calving. Group C (n = 10), clinically healthy puerperal cows. Group D (n = 10), puerperal ketotic cows. The blood serum of ketotic cows was found to have lower levels of T3 (p < 0.01), T4 (p < 0.05), insulin (p > 0.05), cortisol (p > 0.05), glucose (p < 0.01), TG (p < 0.01) and total cholesterol (p < 0.05), and higher (p < 0.01) levels of NEFA and BHB, as compared to the blood levels in healthy pregnant and healthy puerperal cows. Results suggest that ket...otic cows undergo homeorhetic adaptation of the regulation of organic nutrient metabolism being manifested through a decrease in the blood levels of the test hormones, resulting in increased lipomobilization, hypoglycemia, and intensive ketogenesis and lipogenesis in liver cells.
Keywords:
dairy cows / hormones / ketosis / lipids / transition periodSource:
Thai Journal of Veterinary Medicine, 2014, 44, 1, 59-66Publisher:
- Chulalongkorn Univ, Bangkok
Funding / projects:
- Molecular genetic and ecophysiological researches on the protection of autochthonous animal genetic resources, sustaining domestic animals’ welfare, health and reproduction, and safe food production (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46002)
Collections
Institution/Community
Fakultet veterinarske medicineTY - JOUR AU - Đoković, Radojica AU - Cincović, Marko AU - Kurcubić, Vladimir AU - Petrović, Milun D. AU - Lalović, Miroslav AU - Jasović, Boban AU - Stanimirović, Zoran PY - 2014 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1113 AB - The objective of this study was to determine blood levels of cortisol, insulin, triiodothyronine (T3), thyroxine (T4), glucose, non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), triglycerides (TG) and total cholesterol in dairy Holstein cows (n = 40) during the transition period. The test cows were classified into four groups: Group A (n = 10), clinically healthy late-pregnant cows from day 20 to day 10 before calving. Group B (n = 10), clinically healthy late-pregnant cows from day 10 to day 1 before calving. Group C (n = 10), clinically healthy puerperal cows. Group D (n = 10), puerperal ketotic cows. The blood serum of ketotic cows was found to have lower levels of T3 (p < 0.01), T4 (p < 0.05), insulin (p > 0.05), cortisol (p > 0.05), glucose (p < 0.01), TG (p < 0.01) and total cholesterol (p < 0.05), and higher (p < 0.01) levels of NEFA and BHB, as compared to the blood levels in healthy pregnant and healthy puerperal cows. Results suggest that ketotic cows undergo homeorhetic adaptation of the regulation of organic nutrient metabolism being manifested through a decrease in the blood levels of the test hormones, resulting in increased lipomobilization, hypoglycemia, and intensive ketogenesis and lipogenesis in liver cells. PB - Chulalongkorn Univ, Bangkok T2 - Thai Journal of Veterinary Medicine T1 - Endocrine and metabolic status of dairy cows during transition period VL - 44 IS - 1 SP - 59 EP - 66 UR - https://hdl.handle.net/21.15107/rcub_veterinar_1113 ER -
@article{ author = "Đoković, Radojica and Cincović, Marko and Kurcubić, Vladimir and Petrović, Milun D. and Lalović, Miroslav and Jasović, Boban and Stanimirović, Zoran", year = "2014", abstract = "The objective of this study was to determine blood levels of cortisol, insulin, triiodothyronine (T3), thyroxine (T4), glucose, non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), triglycerides (TG) and total cholesterol in dairy Holstein cows (n = 40) during the transition period. The test cows were classified into four groups: Group A (n = 10), clinically healthy late-pregnant cows from day 20 to day 10 before calving. Group B (n = 10), clinically healthy late-pregnant cows from day 10 to day 1 before calving. Group C (n = 10), clinically healthy puerperal cows. Group D (n = 10), puerperal ketotic cows. The blood serum of ketotic cows was found to have lower levels of T3 (p < 0.01), T4 (p < 0.05), insulin (p > 0.05), cortisol (p > 0.05), glucose (p < 0.01), TG (p < 0.01) and total cholesterol (p < 0.05), and higher (p < 0.01) levels of NEFA and BHB, as compared to the blood levels in healthy pregnant and healthy puerperal cows. Results suggest that ketotic cows undergo homeorhetic adaptation of the regulation of organic nutrient metabolism being manifested through a decrease in the blood levels of the test hormones, resulting in increased lipomobilization, hypoglycemia, and intensive ketogenesis and lipogenesis in liver cells.", publisher = "Chulalongkorn Univ, Bangkok", journal = "Thai Journal of Veterinary Medicine", title = "Endocrine and metabolic status of dairy cows during transition period", volume = "44", number = "1", pages = "59-66", url = "https://hdl.handle.net/21.15107/rcub_veterinar_1113" }
Đoković, R., Cincović, M., Kurcubić, V., Petrović, M. D., Lalović, M., Jasović, B.,& Stanimirović, Z.. (2014). Endocrine and metabolic status of dairy cows during transition period. in Thai Journal of Veterinary Medicine Chulalongkorn Univ, Bangkok., 44(1), 59-66. https://hdl.handle.net/21.15107/rcub_veterinar_1113
Đoković R, Cincović M, Kurcubić V, Petrović MD, Lalović M, Jasović B, Stanimirović Z. Endocrine and metabolic status of dairy cows during transition period. in Thai Journal of Veterinary Medicine. 2014;44(1):59-66. https://hdl.handle.net/21.15107/rcub_veterinar_1113 .
Đoković, Radojica, Cincović, Marko, Kurcubić, Vladimir, Petrović, Milun D., Lalović, Miroslav, Jasović, Boban, Stanimirović, Zoran, "Endocrine and metabolic status of dairy cows during transition period" in Thai Journal of Veterinary Medicine, 44, no. 1 (2014):59-66, https://hdl.handle.net/21.15107/rcub_veterinar_1113 .