Morphological characteristics of three classic forms of natural equine glanders - a disease with high zoonotic significance
Apstrakt
Equine glanders is a severe bacterial disease known since ancient times. Although eradicated in the most part of the world it is now considered re-emerging. Considering very scarce literature data, we used from formalin fixed collection material: nasal septum, lung and skin specimens from naturally infected horses. Tissues were grossly examined and photographed. Tissue samples, after standard processing, were stained with HE, Congo red and Groccot and microscopically examined. Gross changes include nodules and ulcers in the nasal mucosa with granulation and scarring, pyogranulomas in the lung tissue and nodules and ulcers of the skin. Microscopically marked inflammation of affected tissues with neutrophilic and mononuclear infiltration and fibrous tissue proliferation were seen. As a potent zoonotic agent it has been already used as a biological weapon in the past.
Ključne reči:
glanders / equine / gross / microscopic changesIzvor:
Acta Veterinaria-Beograd, 2017, 67, 4, 572-577Izdavač:
- Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
DOI: 10.1515/acve-2017-0045
ISSN: 0567-8315
WoS: 000419653200010
Scopus: 2-s2.0-85041597223
Institucija/grupa
Fakultet veterinarske medicineTY - JOUR AU - Aničić, Milan AU - Kukolj, Vladimir AU - Marinković, Darko PY - 2017 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1538 AB - Equine glanders is a severe bacterial disease known since ancient times. Although eradicated in the most part of the world it is now considered re-emerging. Considering very scarce literature data, we used from formalin fixed collection material: nasal septum, lung and skin specimens from naturally infected horses. Tissues were grossly examined and photographed. Tissue samples, after standard processing, were stained with HE, Congo red and Groccot and microscopically examined. Gross changes include nodules and ulcers in the nasal mucosa with granulation and scarring, pyogranulomas in the lung tissue and nodules and ulcers of the skin. Microscopically marked inflammation of affected tissues with neutrophilic and mononuclear infiltration and fibrous tissue proliferation were seen. As a potent zoonotic agent it has been already used as a biological weapon in the past. PB - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd T2 - Acta Veterinaria-Beograd T1 - Morphological characteristics of three classic forms of natural equine glanders - a disease with high zoonotic significance VL - 67 IS - 4 SP - 572 EP - 577 DO - 10.1515/acve-2017-0045 ER -
@article{ author = "Aničić, Milan and Kukolj, Vladimir and Marinković, Darko", year = "2017", abstract = "Equine glanders is a severe bacterial disease known since ancient times. Although eradicated in the most part of the world it is now considered re-emerging. Considering very scarce literature data, we used from formalin fixed collection material: nasal septum, lung and skin specimens from naturally infected horses. Tissues were grossly examined and photographed. Tissue samples, after standard processing, were stained with HE, Congo red and Groccot and microscopically examined. Gross changes include nodules and ulcers in the nasal mucosa with granulation and scarring, pyogranulomas in the lung tissue and nodules and ulcers of the skin. Microscopically marked inflammation of affected tissues with neutrophilic and mononuclear infiltration and fibrous tissue proliferation were seen. As a potent zoonotic agent it has been already used as a biological weapon in the past.", publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd", journal = "Acta Veterinaria-Beograd", title = "Morphological characteristics of three classic forms of natural equine glanders - a disease with high zoonotic significance", volume = "67", number = "4", pages = "572-577", doi = "10.1515/acve-2017-0045" }
Aničić, M., Kukolj, V.,& Marinković, D.. (2017). Morphological characteristics of three classic forms of natural equine glanders - a disease with high zoonotic significance. in Acta Veterinaria-Beograd Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 67(4), 572-577. https://doi.org/10.1515/acve-2017-0045
Aničić M, Kukolj V, Marinković D. Morphological characteristics of three classic forms of natural equine glanders - a disease with high zoonotic significance. in Acta Veterinaria-Beograd. 2017;67(4):572-577. doi:10.1515/acve-2017-0045 .
Aničić, Milan, Kukolj, Vladimir, Marinković, Darko, "Morphological characteristics of three classic forms of natural equine glanders - a disease with high zoonotic significance" in Acta Veterinaria-Beograd, 67, no. 4 (2017):572-577, https://doi.org/10.1515/acve-2017-0045 . .