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Influence of cadmium chloride on the frequency of micronuclei in da and AO rats
dc.creator | Popović-Bubujuk, Slavica | |
dc.creator | Đelić, Ninoslav | |
dc.creator | Muster, Adrian | |
dc.creator | Kataranovski, Dragan | |
dc.creator | Anđelković, Marko | |
dc.date.accessioned | 2020-06-03T14:27:56Z | |
dc.date.available | 2020-06-03T14:27:56Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 0534-0012 | |
dc.identifier.uri | https://vet-erinar.vet.bg.ac.rs/handle/123456789/1661 | |
dc.description.abstract | Heavy metal cadmium (Cd), a well-known environmental hazard, exerts a number of toxic and genotoxic effects. Experimental animals, Albino Oxford (AO) and Dark August (DA) rat strains, were treated intraperitoneally with three different concentrations of cadmium chloride (CdCl2): 0.5, 1, and 2 mg CdCl2 per kg of body weight, while the control animals received equal volume of sterile phosphate buffered saline. In this investigation individuals of both sexes aged 3, 6 and 12 month were used. Frequency of micronuclei formation was evaluated in polychromatic erythrocytes (PCEs), 24h hours after treatment. The results showed that that cadmium-cloride (CdCl2) exibits the genotoxic effects causing an increase of the frequency of micronuclei depending on concentration, sex, age and strain. | en |
dc.publisher | Društvo genetičara Srbije, Beograd | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46002/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173012/RS// | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Genetika | |
dc.subject | Albino Oxford | en |
dc.subject | cadmium | en |
dc.subject | Dark August | en |
dc.subject | micronucleus | en |
dc.subject | rats | en |
dc.title | Influence of cadmium chloride on the frequency of micronuclei in da and AO rats | en |
dc.type | article | |
dc.rights.license | BY-NC-ND | |
dcterms.abstract | Катарановски, Драган; Мустер, Aдриан; Aнђелковић, Марко; Ђелић, Нинослав; Поповић-Бубујук, Славица; | |
dc.citation.volume | 50 | |
dc.citation.issue | 2 | |
dc.citation.spage | 705 | |
dc.citation.epage | 716 | |
dc.citation.other | 50(2): 705-716 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000442685800028 | |
dc.identifier.doi | 10.2298/GENSR1802705P | |
dc.identifier.scopus | 2-s2.0-85056234012 | |
dc.identifier.fulltext | https://vet-erinar.vet.bg.ac.rs/bitstream/id/617/1660.pdf | |
dc.type.version | publishedVersion |