Inkjet-Printed Carbon Nanotube Electrodes Modified with Dimercaptosuccinic Acid-Capped Fe3O4Nanoparticles on Reduced Graphene Oxide Nanosheets for Single-Drop Determination of Trifluoperazine
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2020
Authors
Ognjanović, MilošStanković, Dalibor M.
Jović, Milica
Krstić, Milena
Lesch, Andreas
Girault, Hubert H.
Antić, Branislav
Article (Published version)
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Here, we report the design of a disposable single-drop voltammetric sensor for the quantitative determination of antipsychotic drug trifluoperazine (TFP). The sensor was built using inkjet-printed carbon nanotube (CNT) electrodes, which were modified with dimercaptosuccinic acid (DMSA)-coated magnetite nanoparticles uniformly dispersed over reduced graphene oxide nanosheets (DMSA/Fe3O4/RGO). The used modifying materials were characterized by electron microscopy techniques (transmission electron microscopy (TEM) and field emission-scanning electron microscopy (FE-SEM)), X-ray powder diffraction, ζ-potential measurements, dynamic light scattering (DLS), and electrochemical methods (cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS)). The developed sensor, best operated at pH 7 in the Britton-Robinson buffer solution (BRBS), shows linear electrocatalytic activity with TFP in the concentration range of 1-50 μM, a low detection limit of 0.54 μM, and excellent selectivi...ty, repeatability, and reproducibility with an relative standard deviation (RSD) of 2.4%. A voltammetric approach using square wave voltammetry (SWV) is a sensitive technique under optimized conditions for the analytical determination of submicromolar amounts of TFP. Bare CNT and RGO- and DMSA/Fe3O4-modified CNT electrodes showed lower electrocatalytic activity than the DMSA/Fe3O4/RGO/CNT electrode. The development of this kind of TFP sensor based on nanoparticle-decorated graphene nanosheets can offer a tool for point-of-care applications as sensors in biomedicine.
Keywords:
CNT electrodes / disposable sensor / graphene nanocomposite / magnetite / square wave voltammetrySource:
ACS Applied Nano Materials, 2020, 3, 5, 4654-4662
DOI: 10.1021/acsanm.0c00661
ISSN: 2574-0970
WoS: 000537534900068
Scopus: 2-s2.0-85088110507
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Fakultet veterinarske medicineTY - JOUR AU - Ognjanović, Miloš AU - Stanković, Dalibor M. AU - Jović, Milica AU - Krstić, Milena AU - Lesch, Andreas AU - Girault, Hubert H. AU - Antić, Branislav PY - 2020 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1856 AB - Here, we report the design of a disposable single-drop voltammetric sensor for the quantitative determination of antipsychotic drug trifluoperazine (TFP). The sensor was built using inkjet-printed carbon nanotube (CNT) electrodes, which were modified with dimercaptosuccinic acid (DMSA)-coated magnetite nanoparticles uniformly dispersed over reduced graphene oxide nanosheets (DMSA/Fe3O4/RGO). The used modifying materials were characterized by electron microscopy techniques (transmission electron microscopy (TEM) and field emission-scanning electron microscopy (FE-SEM)), X-ray powder diffraction, ζ-potential measurements, dynamic light scattering (DLS), and electrochemical methods (cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS)). The developed sensor, best operated at pH 7 in the Britton-Robinson buffer solution (BRBS), shows linear electrocatalytic activity with TFP in the concentration range of 1-50 μM, a low detection limit of 0.54 μM, and excellent selectivity, repeatability, and reproducibility with an relative standard deviation (RSD) of 2.4%. A voltammetric approach using square wave voltammetry (SWV) is a sensitive technique under optimized conditions for the analytical determination of submicromolar amounts of TFP. Bare CNT and RGO- and DMSA/Fe3O4-modified CNT electrodes showed lower electrocatalytic activity than the DMSA/Fe3O4/RGO/CNT electrode. The development of this kind of TFP sensor based on nanoparticle-decorated graphene nanosheets can offer a tool for point-of-care applications as sensors in biomedicine. T2 - ACS Applied Nano Materials T1 - Inkjet-Printed Carbon Nanotube Electrodes Modified with Dimercaptosuccinic Acid-Capped Fe3O4Nanoparticles on Reduced Graphene Oxide Nanosheets for Single-Drop Determination of Trifluoperazine VL - 3 IS - 5 SP - 4654 EP - 4662 DO - 10.1021/acsanm.0c00661 ER -
@article{ author = "Ognjanović, Miloš and Stanković, Dalibor M. and Jović, Milica and Krstić, Milena and Lesch, Andreas and Girault, Hubert H. and Antić, Branislav", year = "2020", abstract = "Here, we report the design of a disposable single-drop voltammetric sensor for the quantitative determination of antipsychotic drug trifluoperazine (TFP). The sensor was built using inkjet-printed carbon nanotube (CNT) electrodes, which were modified with dimercaptosuccinic acid (DMSA)-coated magnetite nanoparticles uniformly dispersed over reduced graphene oxide nanosheets (DMSA/Fe3O4/RGO). The used modifying materials were characterized by electron microscopy techniques (transmission electron microscopy (TEM) and field emission-scanning electron microscopy (FE-SEM)), X-ray powder diffraction, ζ-potential measurements, dynamic light scattering (DLS), and electrochemical methods (cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS)). The developed sensor, best operated at pH 7 in the Britton-Robinson buffer solution (BRBS), shows linear electrocatalytic activity with TFP in the concentration range of 1-50 μM, a low detection limit of 0.54 μM, and excellent selectivity, repeatability, and reproducibility with an relative standard deviation (RSD) of 2.4%. A voltammetric approach using square wave voltammetry (SWV) is a sensitive technique under optimized conditions for the analytical determination of submicromolar amounts of TFP. Bare CNT and RGO- and DMSA/Fe3O4-modified CNT electrodes showed lower electrocatalytic activity than the DMSA/Fe3O4/RGO/CNT electrode. The development of this kind of TFP sensor based on nanoparticle-decorated graphene nanosheets can offer a tool for point-of-care applications as sensors in biomedicine.", journal = "ACS Applied Nano Materials", title = "Inkjet-Printed Carbon Nanotube Electrodes Modified with Dimercaptosuccinic Acid-Capped Fe3O4Nanoparticles on Reduced Graphene Oxide Nanosheets for Single-Drop Determination of Trifluoperazine", volume = "3", number = "5", pages = "4654-4662", doi = "10.1021/acsanm.0c00661" }
Ognjanović, M., Stanković, D. M., Jović, M., Krstić, M., Lesch, A., Girault, H. H.,& Antić, B.. (2020). Inkjet-Printed Carbon Nanotube Electrodes Modified with Dimercaptosuccinic Acid-Capped Fe3O4Nanoparticles on Reduced Graphene Oxide Nanosheets for Single-Drop Determination of Trifluoperazine. in ACS Applied Nano Materials, 3(5), 4654-4662. https://doi.org/10.1021/acsanm.0c00661
Ognjanović M, Stanković DM, Jović M, Krstić M, Lesch A, Girault HH, Antić B. Inkjet-Printed Carbon Nanotube Electrodes Modified with Dimercaptosuccinic Acid-Capped Fe3O4Nanoparticles on Reduced Graphene Oxide Nanosheets for Single-Drop Determination of Trifluoperazine. in ACS Applied Nano Materials. 2020;3(5):4654-4662. doi:10.1021/acsanm.0c00661 .
Ognjanović, Miloš, Stanković, Dalibor M., Jović, Milica, Krstić, Milena, Lesch, Andreas, Girault, Hubert H., Antić, Branislav, "Inkjet-Printed Carbon Nanotube Electrodes Modified with Dimercaptosuccinic Acid-Capped Fe3O4Nanoparticles on Reduced Graphene Oxide Nanosheets for Single-Drop Determination of Trifluoperazine" in ACS Applied Nano Materials, 3, no. 5 (2020):4654-4662, https://doi.org/10.1021/acsanm.0c00661 . .