TY  - JOUR
AU  - Levent, Gizem
AU  - Božić, Aleksandar
AU  - Petrujkić, Branko
AU  - Callaway, Todd R.
AU  - Poole, Toni L.
AU  - Crippen, Tawni L.
AU  - Harvey, Roger B.
AU  - Ochoa-García, Pedro
AU  - Corral-Luna, Agustin
AU  - Yeater, Kathleen M.
AU  - Anderson, Robin C.
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3703
AB  - Livestock producers need new technologies to maintain the optimal health and wellbeing of their animals while minimizing the risks of propagating and disseminating pathogenic and
antimicrobial-resistant bacteria to humans or other animals. Where possible, these interventions
should contribute to the efficiency and profitability of animal production to avoid passing costs on
to consumers. In this study, we examined the potential of nitroethane, 3-nitro-1-propionate, ethyl
nitroacetate, taurine and L-cysteinesulfinic acid to modulate rumen methane production, a digestive
inefficiency that results in the loss of up to 12% of the host’s dietary energy intake and a major
contributor of methane as a greenhouse gas to the atmosphere. The potential for these compounds
to inhibit the foodborne pathogens, Escherichia coli O157:H7 and Salmonella Typhimurium DT104,
was also tested. The results from the present study revealed that anaerobically grown O157:H7 and
DT104 treated with the methanogenic inhibitor, ethyl nitroacetate, at concentrations of 3 and 9 mM
had decreased (p < 0.05) mean specific growth rates of O157:H7 (by 22 to 36%) and of DT104 (by 16 to
26%) when compared to controls (0.823 and 0.886 h−1
, respectively). The growth rates of O157:H7 and
DT104 were decreased (p < 0.05) from controls by 31 to 73% and by 41 to 78% by α-lipoic acid, which
we also found to inhibit in vitro rumen methanogenesis up to 66% (p < 0.05). Ethyl nitroacetate was
mainly bacteriostatic, whereas 9 mM α-lipoic acid decreased (p < 0.05) maximal optical densities
(measured at 600 nm) of O157:H7 and DT104 by 25 and 42% compared to controls (0.448 and 0.451,
respectively). In the present study, the other oxidized nitro and organosulfur compounds were neither
antimicrobial nor anti-methanogenic.
PB  - MDPI
T2  - Microorganisms
T1  - Assessment of potential anti-methanogenic and antimicrobial activity of ethyl nitroacetate, α-lipoic acid, taurine and L-cysteinesulfinic acid In vitro
VL  - 12
IS  - 1
SP  - 34
DO  - 10.3390/microorganisms12010034
ER  - 

@article{
author = "Levent, Gizem and Božić, Aleksandar and Petrujkić, Branko and Callaway, Todd R. and Poole, Toni L. and Crippen, Tawni L. and Harvey, Roger B. and Ochoa-García, Pedro and Corral-Luna, Agustin and Yeater, Kathleen M. and Anderson, Robin C.",
year = "2024",
abstract = "Livestock producers need new technologies to maintain the optimal health and wellbeing of their animals while minimizing the risks of propagating and disseminating pathogenic and
antimicrobial-resistant bacteria to humans or other animals. Where possible, these interventions
should contribute to the efficiency and profitability of animal production to avoid passing costs on
to consumers. In this study, we examined the potential of nitroethane, 3-nitro-1-propionate, ethyl
nitroacetate, taurine and L-cysteinesulfinic acid to modulate rumen methane production, a digestive
inefficiency that results in the loss of up to 12% of the host’s dietary energy intake and a major
contributor of methane as a greenhouse gas to the atmosphere. The potential for these compounds
to inhibit the foodborne pathogens, Escherichia coli O157:H7 and Salmonella Typhimurium DT104,
was also tested. The results from the present study revealed that anaerobically grown O157:H7 and
DT104 treated with the methanogenic inhibitor, ethyl nitroacetate, at concentrations of 3 and 9 mM
had decreased (p < 0.05) mean specific growth rates of O157:H7 (by 22 to 36%) and of DT104 (by 16 to
26%) when compared to controls (0.823 and 0.886 h−1
, respectively). The growth rates of O157:H7 and
DT104 were decreased (p < 0.05) from controls by 31 to 73% and by 41 to 78% by α-lipoic acid, which
we also found to inhibit in vitro rumen methanogenesis up to 66% (p < 0.05). Ethyl nitroacetate was
mainly bacteriostatic, whereas 9 mM α-lipoic acid decreased (p < 0.05) maximal optical densities
(measured at 600 nm) of O157:H7 and DT104 by 25 and 42% compared to controls (0.448 and 0.451,
respectively). In the present study, the other oxidized nitro and organosulfur compounds were neither
antimicrobial nor anti-methanogenic.",
publisher = "MDPI",
journal = "Microorganisms",
title = "Assessment of potential anti-methanogenic and antimicrobial activity of ethyl nitroacetate, α-lipoic acid, taurine and L-cysteinesulfinic acid In vitro",
volume = "12",
number = "1",
pages = "34",
doi = "10.3390/microorganisms12010034"
}

Levent, G., Božić, A., Petrujkić, B., Callaway, T. R., Poole, T. L., Crippen, T. L., Harvey, R. B., Ochoa-García, P., Corral-Luna, A., Yeater, K. M.,& Anderson, R. C.. (2024). Assessment of potential anti-methanogenic and antimicrobial activity of ethyl nitroacetate, α-lipoic acid, taurine and L-cysteinesulfinic acid In vitro. in Microorganisms
MDPI., 12(1), 34.
https://doi.org/10.3390/microorganisms12010034

Levent G, Božić A, Petrujkić B, Callaway TR, Poole TL, Crippen TL, Harvey RB, Ochoa-García P, Corral-Luna A, Yeater KM, Anderson RC. Assessment of potential anti-methanogenic and antimicrobial activity of ethyl nitroacetate, α-lipoic acid, taurine and L-cysteinesulfinic acid In vitro. in Microorganisms. 2024;12(1):34.
doi:10.3390/microorganisms12010034 .

Levent, Gizem, Božić, Aleksandar, Petrujkić, Branko, Callaway, Todd R., Poole, Toni L., Crippen, Tawni L., Harvey, Roger B., Ochoa-García, Pedro, Corral-Luna, Agustin, Yeater, Kathleen M., Anderson, Robin C., "Assessment of potential anti-methanogenic and antimicrobial activity of ethyl nitroacetate, α-lipoic acid, taurine and L-cysteinesulfinic acid In vitro" in Microorganisms, 12, no. 1 (2024):34,
https://doi.org/10.3390/microorganisms12010034 . .

TY  - JOUR
AU  - Vuković, Dejan
AU  - Božić, Aleksandar
AU  - Relić, Renata
AU  - Stančić, Blagoje
AU  - Gvozdić, Dragan
AU  - Kucević, Denis
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1413
AB  - An experiment was conducted to investigate the effects of hormonal synchronization of ovulation on progesterone concentrations in milk and blood serum and on reproductive performance. Sixty Holstein-Friesian cows averaging 8000 L over 305 days of lactation were divided into 2 groups of 30 animals. One-factor ANOVA and a t-test of progesterone concentrations in venous serum and milk revealed that the lowest concentrations of progesterone in milk (Ovsynch 5.8 + 1.0 ng/mL; control 4.5 + 0.6 ng/mL) and blood serum (Ovsynch 1.3 +/- 0.9 ng/mL; control 1.4 +/- 0.5 ng/mL) in both groups were found on the day of estrus or artificial insemination (AI) (both P < 0.05). Increases in the concentrations of progesterone in milk (Ovsynch 17.6 +/- 4.3 ng/mL; control 10.5 +/- 1.9 ng/mL) and blood serum (Ovsynch 3.6 +/- 1.1 ng/mL; control 4.0 +/- 1.0 ng/mL) were observed on day 7 after AI (both P < 0.05). Concentrations of progesterone in milk and blood serum in nonpregnant cows were reduced on day 21 after AI. Assessment of reproductive performance revealed that the application of treatment shortened the duration of the service period (Ovsynch 76 days; control 83 days) and the calving interval (Ovsynch 376 days; control 382 days).
PB  - Scientific Technical Research Council Turkey-Tubitak, Ankara
T2  - Turkish Journal of Veterinary & Animal Sciences
T1  - Progesterone concentration in milk and blood serum and reproductive efficiency of cows after Ovsynch treatment
VL  - 40
IS  - 1
SP  - 75
EP  - 80
DO  - 10.3906/vet-1505-17
ER  - 

@article{
author = "Vuković, Dejan and Božić, Aleksandar and Relić, Renata and Stančić, Blagoje and Gvozdić, Dragan and Kucević, Denis",
year = "2016",
abstract = "An experiment was conducted to investigate the effects of hormonal synchronization of ovulation on progesterone concentrations in milk and blood serum and on reproductive performance. Sixty Holstein-Friesian cows averaging 8000 L over 305 days of lactation were divided into 2 groups of 30 animals. One-factor ANOVA and a t-test of progesterone concentrations in venous serum and milk revealed that the lowest concentrations of progesterone in milk (Ovsynch 5.8 + 1.0 ng/mL; control 4.5 + 0.6 ng/mL) and blood serum (Ovsynch 1.3 +/- 0.9 ng/mL; control 1.4 +/- 0.5 ng/mL) in both groups were found on the day of estrus or artificial insemination (AI) (both P < 0.05). Increases in the concentrations of progesterone in milk (Ovsynch 17.6 +/- 4.3 ng/mL; control 10.5 +/- 1.9 ng/mL) and blood serum (Ovsynch 3.6 +/- 1.1 ng/mL; control 4.0 +/- 1.0 ng/mL) were observed on day 7 after AI (both P < 0.05). Concentrations of progesterone in milk and blood serum in nonpregnant cows were reduced on day 21 after AI. Assessment of reproductive performance revealed that the application of treatment shortened the duration of the service period (Ovsynch 76 days; control 83 days) and the calving interval (Ovsynch 376 days; control 382 days).",
publisher = "Scientific Technical Research Council Turkey-Tubitak, Ankara",
journal = "Turkish Journal of Veterinary & Animal Sciences",
title = "Progesterone concentration in milk and blood serum and reproductive efficiency of cows after Ovsynch treatment",
volume = "40",
number = "1",
pages = "75-80",
doi = "10.3906/vet-1505-17"
}

Vuković, D., Božić, A., Relić, R., Stančić, B., Gvozdić, D.,& Kucević, D.. (2016). Progesterone concentration in milk and blood serum and reproductive efficiency of cows after Ovsynch treatment. in Turkish Journal of Veterinary & Animal Sciences
Scientific Technical Research Council Turkey-Tubitak, Ankara., 40(1), 75-80.
https://doi.org/10.3906/vet-1505-17

Vuković D, Božić A, Relić R, Stančić B, Gvozdić D, Kucević D. Progesterone concentration in milk and blood serum and reproductive efficiency of cows after Ovsynch treatment. in Turkish Journal of Veterinary & Animal Sciences. 2016;40(1):75-80.
doi:10.3906/vet-1505-17 .

Vuković, Dejan, Božić, Aleksandar, Relić, Renata, Stančić, Blagoje, Gvozdić, Dragan, Kucević, Denis, "Progesterone concentration in milk and blood serum and reproductive efficiency of cows after Ovsynch treatment" in Turkish Journal of Veterinary & Animal Sciences, 40, no. 1 (2016):75-80,
https://doi.org/10.3906/vet-1505-17 . .

TY  - JOUR
AU  - Vuković, D.
AU  - Stančić, Ivan
AU  - Gvozdić, Dragan
AU  - Kucević, D.
AU  - Božić, Aleksandar
AU  - Jovanović, Ivan B.
AU  - Milanović, Svetlana
AU  - Stančić, Blagoje
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1107
AB  - Fertiliy rate in high milk-yield dairy cows, with prolonged postpartum anestrus, was investigated after treatment by Ovsynch protocol. Thirty cows with follicular cysts or unovulated follicles (around 1.2 cm in diameter), without detected estrus up to 60 days post partum, were treated by Ovsynch protocol. The date of the first GnRH injection was defined as day 0. On day 6. was given prostaglandin F2α (PGF2a) and second GnRH injection 48 h after PGF2 α (day 8). All treated cows were terminally inseminated at day 9 (without estrus detection), i.e. 12-14 h after the last GnRH injection. The blood serum progesterone concentration was determined by ELISA method, in blood samples taken from v. jugularis, at the day of AI.The blood serum concentration of progesterone on the day of AI was low in Ovsynch treated (1.8 ng/mL) and in control cows (1.5 ng/mL). Obtainedcalving rate was not significant different between treated and control cows (57:60%, respectively, p > 0.05). Our results show that Ovsynch protocol treatment can be a successful method for control of prolonged postpartum anestrus in high milk-yield cows.
PB  - Eugen Ulmer Gmbh Co, Stuttgart
T2  - Zuchtungskunde
T1  - Influence of ovsynch-treatment on concentration of progesterone in blood serum and pregnancy rates after artificial insemination in cows [Einfluss einer Ovsynch-Behandlung auf die Progesteronkonzentrationen im Blutserum und Trächtigkeitsraten bei Kühen na
VL  - 86
IS  - 2
SP  - 123
EP  - 129
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_1107
ER  - 

@article{
author = "Vuković, D. and Stančić, Ivan and Gvozdić, Dragan and Kucević, D. and Božić, Aleksandar and Jovanović, Ivan B. and Milanović, Svetlana and Stančić, Blagoje",
year = "2014",
abstract = "Fertiliy rate in high milk-yield dairy cows, with prolonged postpartum anestrus, was investigated after treatment by Ovsynch protocol. Thirty cows with follicular cysts or unovulated follicles (around 1.2 cm in diameter), without detected estrus up to 60 days post partum, were treated by Ovsynch protocol. The date of the first GnRH injection was defined as day 0. On day 6. was given prostaglandin F2α (PGF2a) and second GnRH injection 48 h after PGF2 α (day 8). All treated cows were terminally inseminated at day 9 (without estrus detection), i.e. 12-14 h after the last GnRH injection. The blood serum progesterone concentration was determined by ELISA method, in blood samples taken from v. jugularis, at the day of AI.The blood serum concentration of progesterone on the day of AI was low in Ovsynch treated (1.8 ng/mL) and in control cows (1.5 ng/mL). Obtainedcalving rate was not significant different between treated and control cows (57:60%, respectively, p > 0.05). Our results show that Ovsynch protocol treatment can be a successful method for control of prolonged postpartum anestrus in high milk-yield cows.",
publisher = "Eugen Ulmer Gmbh Co, Stuttgart",
journal = "Zuchtungskunde",
title = "Influence of ovsynch-treatment on concentration of progesterone in blood serum and pregnancy rates after artificial insemination in cows [Einfluss einer Ovsynch-Behandlung auf die Progesteronkonzentrationen im Blutserum und Trächtigkeitsraten bei Kühen na",
volume = "86",
number = "2",
pages = "123-129",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_1107"
}

Vuković, D., Stančić, I., Gvozdić, D., Kucević, D., Božić, A., Jovanović, I. B., Milanović, S.,& Stančić, B.. (2014). Influence of ovsynch-treatment on concentration of progesterone in blood serum and pregnancy rates after artificial insemination in cows [Einfluss einer Ovsynch-Behandlung auf die Progesteronkonzentrationen im Blutserum und Trächtigkeitsraten bei Kühen na. in Zuchtungskunde
Eugen Ulmer Gmbh Co, Stuttgart., 86(2), 123-129.
https://hdl.handle.net/21.15107/rcub_veterinar_1107

Vuković D, Stančić I, Gvozdić D, Kucević D, Božić A, Jovanović IB, Milanović S, Stančić B. Influence of ovsynch-treatment on concentration of progesterone in blood serum and pregnancy rates after artificial insemination in cows [Einfluss einer Ovsynch-Behandlung auf die Progesteronkonzentrationen im Blutserum und Trächtigkeitsraten bei Kühen na. in Zuchtungskunde. 2014;86(2):123-129.
https://hdl.handle.net/21.15107/rcub_veterinar_1107 .

Vuković, D., Stančić, Ivan, Gvozdić, Dragan, Kucević, D., Božić, Aleksandar, Jovanović, Ivan B., Milanović, Svetlana, Stančić, Blagoje, "Influence of ovsynch-treatment on concentration of progesterone in blood serum and pregnancy rates after artificial insemination in cows [Einfluss einer Ovsynch-Behandlung auf die Progesteronkonzentrationen im Blutserum und Trächtigkeitsraten bei Kühen na" in Zuchtungskunde, 86, no. 2 (2014):123-129,
https://hdl.handle.net/21.15107/rcub_veterinar_1107 .

TY  - JOUR
AU  - Gvozdić, Dragan
AU  - Dovenski, Toni
AU  - Stančić, Ivan
AU  - Stančić, Blagoje
AU  - Božić, Aleksandar
AU  - Jovanović, Ivan B.
AU  - Atanasov, Branko
AU  - Šuluburić, Adam
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/975
AB  - Reproduction efficiency in dairy cows is declining all over the world. Epidemiologic studies suggest that diseases have greater effect on herd fertility compared to the parameters like milk production. Immediate solution to the problem of infertility may be the application of some method of hormonal manipulation of estrous cycle in dairy cows. Reproductive system ultrasound examination enables today's veterinarians to visualize ovarian changes during the estrous cycle, giving them a chance to intervene with exogenous hormonal inhibition and/or stimulation of temporary ovarian structures at the appropriate time. Summarizing possible hormonal methods for estrous cycle manipulation we have analyzed following protocols: prostaglandin based protocols, prostaglandin + progestagensin combination, regimes using prostaglandin + gonadotropin-releasing hormone (GnRH) and prostaglandin + GnRH + estradiol protocols. In dairy herds where estrus detection does not represent a significant problem, prostaglandin based or Select Synch protocols are methods of choice for the hormonal manipulation of estrous cycle. However, if there are problems regarding estrus detection Ovsynch or Presynch + Ovsynch could be an effective alternative for the hormonal manipulation of estrous cycle. Furthermore, fixed time artificial insemination (TAI) could be modified to coincide with the second GnRH injection, thus reducing the time and number of visits. .
AB  - Efikasnost reprodukcije kod mlečnih krava ima tendenciju pogoršanja u svim delovima sveta pa i u Republici Srbiji. Epidemiološka ispitivanja ukazuju da se razlozi za smanjenje reproduktivne efikasnosti pre moraju tražiti u parametrima vezanim za pojavu različitih oboljenja nego u porastu proizvodnje mleka. Međutim, trenutno rešenje za problem smanjene plodnosti mlečnih krava najčešće se traži u primeni različitih hormonalnih metoda za manipulaciju estrusnim ciklusom kod mlečnih krava. Ultrazvučni pregled reproduktivnog trakta kod mlečnih krava je omogućio veterinarima da direktno prate promene na jajnicima i uterusu tokom estrusnog ciklusa, otvarajući prostor za pravovremenu primenu hormona radi inhibicije/stimulacije privremenih endokrinih struktura na jajnicima. U našem pokušaju da sumiramo najznačajnije hormonalne metode za manipulaciju estrusnog ciklusa kod mlečnih krava analizirali smo protokole bazirane isključivo na aplikaciji prostaglandina, metode zasnovane na kombinovanju prostaglandina i progestagena, režime manipulacije bazirane na primeni kombinacije prostaglandina i gonadotropnog oslobađajućeg hormona (GnRH), kao i primenu prostaglandina, GnRH i estradiola. U stadima mlečnih krava gde je optimalna detekcija estrusa metoda izbora za hormonalnu manipulaciju estrusnog ciklusa je tzv. Select Synch protokol. Ukoliko je na farmi ustanovljen prisutan problem detekcija estrusa može se primeniti Ovsynch protokol ili kombinacija Presynch i Ovsynch protokola za hormonalnu manipulaciju estrusnog ciklusa. Fiksno vreme veštačkog osemenjavanja koje se sprovodi u toku Ovsynch protokola može se pomeriti tako da se vrši u vreme druge aplikacije GnRH, čime se smanjuje broj fizičkih intervencija i skraćuje trajanje protokola. .
PB  - Univerzitet u Novom Sadu - Poljoprivredni fakultet, Novi Sad i Naučni institut za ratarstvo i povrtarstvo, Novi Sad
T2  - Savremena poljoprivreda
T1  - Hormonal methods for estrous cycle manipulation in dairy cows
T1  - Hormonalne metode za manipulaciju estrusnim ciklusom kod mlečnih krava
VL  - 62
IS  - 3-4
SP  - 319
EP  - 332
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_975
ER  - 

@article{
author = "Gvozdić, Dragan and Dovenski, Toni and Stančić, Ivan and Stančić, Blagoje and Božić, Aleksandar and Jovanović, Ivan B. and Atanasov, Branko and Šuluburić, Adam",
year = "2013",
abstract = "Reproduction efficiency in dairy cows is declining all over the world. Epidemiologic studies suggest that diseases have greater effect on herd fertility compared to the parameters like milk production. Immediate solution to the problem of infertility may be the application of some method of hormonal manipulation of estrous cycle in dairy cows. Reproductive system ultrasound examination enables today's veterinarians to visualize ovarian changes during the estrous cycle, giving them a chance to intervene with exogenous hormonal inhibition and/or stimulation of temporary ovarian structures at the appropriate time. Summarizing possible hormonal methods for estrous cycle manipulation we have analyzed following protocols: prostaglandin based protocols, prostaglandin + progestagensin combination, regimes using prostaglandin + gonadotropin-releasing hormone (GnRH) and prostaglandin + GnRH + estradiol protocols. In dairy herds where estrus detection does not represent a significant problem, prostaglandin based or Select Synch protocols are methods of choice for the hormonal manipulation of estrous cycle. However, if there are problems regarding estrus detection Ovsynch or Presynch + Ovsynch could be an effective alternative for the hormonal manipulation of estrous cycle. Furthermore, fixed time artificial insemination (TAI) could be modified to coincide with the second GnRH injection, thus reducing the time and number of visits. ., Efikasnost reprodukcije kod mlečnih krava ima tendenciju pogoršanja u svim delovima sveta pa i u Republici Srbiji. Epidemiološka ispitivanja ukazuju da se razlozi za smanjenje reproduktivne efikasnosti pre moraju tražiti u parametrima vezanim za pojavu različitih oboljenja nego u porastu proizvodnje mleka. Međutim, trenutno rešenje za problem smanjene plodnosti mlečnih krava najčešće se traži u primeni različitih hormonalnih metoda za manipulaciju estrusnim ciklusom kod mlečnih krava. Ultrazvučni pregled reproduktivnog trakta kod mlečnih krava je omogućio veterinarima da direktno prate promene na jajnicima i uterusu tokom estrusnog ciklusa, otvarajući prostor za pravovremenu primenu hormona radi inhibicije/stimulacije privremenih endokrinih struktura na jajnicima. U našem pokušaju da sumiramo najznačajnije hormonalne metode za manipulaciju estrusnog ciklusa kod mlečnih krava analizirali smo protokole bazirane isključivo na aplikaciji prostaglandina, metode zasnovane na kombinovanju prostaglandina i progestagena, režime manipulacije bazirane na primeni kombinacije prostaglandina i gonadotropnog oslobađajućeg hormona (GnRH), kao i primenu prostaglandina, GnRH i estradiola. U stadima mlečnih krava gde je optimalna detekcija estrusa metoda izbora za hormonalnu manipulaciju estrusnog ciklusa je tzv. Select Synch protokol. Ukoliko je na farmi ustanovljen prisutan problem detekcija estrusa može se primeniti Ovsynch protokol ili kombinacija Presynch i Ovsynch protokola za hormonalnu manipulaciju estrusnog ciklusa. Fiksno vreme veštačkog osemenjavanja koje se sprovodi u toku Ovsynch protokola može se pomeriti tako da se vrši u vreme druge aplikacije GnRH, čime se smanjuje broj fizičkih intervencija i skraćuje trajanje protokola. .",
publisher = "Univerzitet u Novom Sadu - Poljoprivredni fakultet, Novi Sad i Naučni institut za ratarstvo i povrtarstvo, Novi Sad",
journal = "Savremena poljoprivreda",
title = "Hormonal methods for estrous cycle manipulation in dairy cows, Hormonalne metode za manipulaciju estrusnim ciklusom kod mlečnih krava",
volume = "62",
number = "3-4",
pages = "319-332",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_975"
}

Gvozdić, D., Dovenski, T., Stančić, I., Stančić, B., Božić, A., Jovanović, I. B., Atanasov, B.,& Šuluburić, A.. (2013). Hormonal methods for estrous cycle manipulation in dairy cows. in Savremena poljoprivreda
Univerzitet u Novom Sadu - Poljoprivredni fakultet, Novi Sad i Naučni institut za ratarstvo i povrtarstvo, Novi Sad., 62(3-4), 319-332.
https://hdl.handle.net/21.15107/rcub_veterinar_975

Gvozdić D, Dovenski T, Stančić I, Stančić B, Božić A, Jovanović IB, Atanasov B, Šuluburić A. Hormonal methods for estrous cycle manipulation in dairy cows. in Savremena poljoprivreda. 2013;62(3-4):319-332.
https://hdl.handle.net/21.15107/rcub_veterinar_975 .

Gvozdić, Dragan, Dovenski, Toni, Stančić, Ivan, Stančić, Blagoje, Božić, Aleksandar, Jovanović, Ivan B., Atanasov, Branko, Šuluburić, Adam, "Hormonal methods for estrous cycle manipulation in dairy cows" in Savremena poljoprivreda, 62, no. 3-4 (2013):319-332,
https://hdl.handle.net/21.15107/rcub_veterinar_975 .

TY  - JOUR
AU  - Gvozdić, Dragan
AU  - Stančić, Ivan
AU  - Savović, Milan
AU  - Stančić, Blagoje
AU  - Božić, Aleksandar
AU  - Milanović, Svetlana
AU  - Jovanović, Ivan B.
AU  - Barna, Tomislav
PY  - 2011
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/845
AB  - The aim of this work was to determine incidence of calving and postcalving reproduction disorders and their effect on the major parameters of cows reproductive efficiency at dairy farm in the R. Serbia. Total number of 1835 high-milking dairy cows (av. milk production >8500L/305d of lactation) records has been reviewed during one year period, at the large dairy farm in area of Vojvodina (R. Serbia). Normal calving and puerperal period without health problems was observed at 583 cows (27,6%), while different abnormalities during and after calving were recorded in 1252 cows (72,4%). The highest percentages of registered peripartal disorders were dystocia and endometritis (62% and 64%, respectively), affecting almost the same percentage of cows. Peripartal disorders had statistically significant influence (P lt 0.05) on the increase of number of services/conception (3,5 vs. 2,7, reproductive disorders vs. healthy cows, respectively), prolongation of the interval from first postpartal insemination till conception (110 vs. 57 days, reproductive disorders vs. healthy cows, respectively), and increase of days open period (214 vs. 146 days, reproductive disorders vs. healthy cows, respectively). This results have confirmed increased incidence of reproduction disorders during calving and postcalving period that significantly reduces reproductive efficiency in high milking dairy cows after parturition.
AB  - Istraživanja u mnogim zemljama, tokom poslednjih decenija, pokazuju permanentan pad reproduktivne efikasnosti krava visoke mlečnosti. Cilj ovog rada je da se utvrdi da li i u kojoj meri, peripartalni poremećaji imaju uticaja na osnovne parametre reproduktivne efikasnosti krava u našim proizvodnim uslovima. Istraživanjem je obuhvaćeno ukupno 1835 krava, tokom jedne godine, na jednoj velikoj farmi sa visokom proizvodnjom mleka (prosečna proizvodnja >8500L/305 dana laktacije) u regionu Vojvodine (Republika Srbija). Od ukupnog broja ispitivanih krava, telenje je prošlo bez poremećaja kod 583 krave (27,6%), a različiti poremećaji tokom i posle telenja su ustanovljeni kod 1.252 krave (72,4%). Najčešće ustanovljeni peripartalni poremećaji kod visoko mlečnih krava su teško teljenje (62%) i endometritis (64%). Peripartalni poremećaji imaju statistički značajan uticaj (P lt 0,05) na povećanje indeksa osemenjavanja (3,5 prema 2,7), produženje intervala od prvog do fertilnog osemenjavanja (57 prema 110 dana), kao i na produženje trajanja servis perioda (146 prema 214 dana), u poređenju sa kravama bez poremećaja. Dobijeni rezultati pokazuju da na farmama visoko mlečnih krava povišena učestalost peripartalnih reproduktivnih poremećaja koji značajno utiču na smanjenje reproduktivne efikasnosti krava nakon partusa.
PB  - Univerzitet u Novom Sadu - Poljoprivredni fakultet, Novi Sad i Naučni institut za ratarstvo i povrtarstvo, Novi Sad
T2  - Savremena poljoprivreda
T1  - Reproductive efficiency in high-milking dairy cows after calving
T1  - Reproduktivna efikasnost visoko-mlečnih krava posle telenja
VL  - 60
IS  - 1-2
SP  - 86
EP  - 97
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_845
ER  - 

@article{
author = "Gvozdić, Dragan and Stančić, Ivan and Savović, Milan and Stančić, Blagoje and Božić, Aleksandar and Milanović, Svetlana and Jovanović, Ivan B. and Barna, Tomislav",
year = "2011",
abstract = "The aim of this work was to determine incidence of calving and postcalving reproduction disorders and their effect on the major parameters of cows reproductive efficiency at dairy farm in the R. Serbia. Total number of 1835 high-milking dairy cows (av. milk production >8500L/305d of lactation) records has been reviewed during one year period, at the large dairy farm in area of Vojvodina (R. Serbia). Normal calving and puerperal period without health problems was observed at 583 cows (27,6%), while different abnormalities during and after calving were recorded in 1252 cows (72,4%). The highest percentages of registered peripartal disorders were dystocia and endometritis (62% and 64%, respectively), affecting almost the same percentage of cows. Peripartal disorders had statistically significant influence (P lt 0.05) on the increase of number of services/conception (3,5 vs. 2,7, reproductive disorders vs. healthy cows, respectively), prolongation of the interval from first postpartal insemination till conception (110 vs. 57 days, reproductive disorders vs. healthy cows, respectively), and increase of days open period (214 vs. 146 days, reproductive disorders vs. healthy cows, respectively). This results have confirmed increased incidence of reproduction disorders during calving and postcalving period that significantly reduces reproductive efficiency in high milking dairy cows after parturition., Istraživanja u mnogim zemljama, tokom poslednjih decenija, pokazuju permanentan pad reproduktivne efikasnosti krava visoke mlečnosti. Cilj ovog rada je da se utvrdi da li i u kojoj meri, peripartalni poremećaji imaju uticaja na osnovne parametre reproduktivne efikasnosti krava u našim proizvodnim uslovima. Istraživanjem je obuhvaćeno ukupno 1835 krava, tokom jedne godine, na jednoj velikoj farmi sa visokom proizvodnjom mleka (prosečna proizvodnja >8500L/305 dana laktacije) u regionu Vojvodine (Republika Srbija). Od ukupnog broja ispitivanih krava, telenje je prošlo bez poremećaja kod 583 krave (27,6%), a različiti poremećaji tokom i posle telenja su ustanovljeni kod 1.252 krave (72,4%). Najčešće ustanovljeni peripartalni poremećaji kod visoko mlečnih krava su teško teljenje (62%) i endometritis (64%). Peripartalni poremećaji imaju statistički značajan uticaj (P lt 0,05) na povećanje indeksa osemenjavanja (3,5 prema 2,7), produženje intervala od prvog do fertilnog osemenjavanja (57 prema 110 dana), kao i na produženje trajanja servis perioda (146 prema 214 dana), u poređenju sa kravama bez poremećaja. Dobijeni rezultati pokazuju da na farmama visoko mlečnih krava povišena učestalost peripartalnih reproduktivnih poremećaja koji značajno utiču na smanjenje reproduktivne efikasnosti krava nakon partusa.",
publisher = "Univerzitet u Novom Sadu - Poljoprivredni fakultet, Novi Sad i Naučni institut za ratarstvo i povrtarstvo, Novi Sad",
journal = "Savremena poljoprivreda",
title = "Reproductive efficiency in high-milking dairy cows after calving, Reproduktivna efikasnost visoko-mlečnih krava posle telenja",
volume = "60",
number = "1-2",
pages = "86-97",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_845"
}

Gvozdić, D., Stančić, I., Savović, M., Stančić, B., Božić, A., Milanović, S., Jovanović, I. B.,& Barna, T.. (2011). Reproductive efficiency in high-milking dairy cows after calving. in Savremena poljoprivreda
Univerzitet u Novom Sadu - Poljoprivredni fakultet, Novi Sad i Naučni institut za ratarstvo i povrtarstvo, Novi Sad., 60(1-2), 86-97.
https://hdl.handle.net/21.15107/rcub_veterinar_845

Gvozdić D, Stančić I, Savović M, Stančić B, Božić A, Milanović S, Jovanović IB, Barna T. Reproductive efficiency in high-milking dairy cows after calving. in Savremena poljoprivreda. 2011;60(1-2):86-97.
https://hdl.handle.net/21.15107/rcub_veterinar_845 .

Gvozdić, Dragan, Stančić, Ivan, Savović, Milan, Stančić, Blagoje, Božić, Aleksandar, Milanović, Svetlana, Jovanović, Ivan B., Barna, Tomislav, "Reproductive efficiency in high-milking dairy cows after calving" in Savremena poljoprivreda, 60, no. 1-2 (2011):86-97,
https://hdl.handle.net/21.15107/rcub_veterinar_845 .

TY  - JOUR
AU  - Stančić, Ivan
AU  - Stančić, Blagoje
AU  - Božić, Aleksandar
AU  - Anderson, Robin C.
AU  - Harvey, Roger B.
AU  - Gvozdić, Dragan
PY  - 2011
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/755
AB  - About 30% of the total number of gilts selected for reproduction at the large breeding farm units in Vojvodina (Republic of Serbia) are culled due to prolonged pre-insemination anoestrus (estrus not detected until 8 mo of age). The aim of this study was to provide the answer to the following question: do the culling gilts reach cyclic ovarian activity at all? One hundred seventy five culled gilts in which external estrus manifestations were not detected by 8 mo of age were sacrificed and their reproductive organs were examined for determination of sexual maturity (ovaries exhibiting pre-ovulatory follicles 8 to 11 mm in diameter, corpora hemorrhagica, corpora lutea and corpora albicantia). Uterine weights and horn length were also determined. Functional ovaries were observed in 107 (61.1%) examined gilts, with 62 animals having one and 45 having two puberty ovarian cycles (57.9% and 42.1%, respectively). Pathomorphological changes which could result in prolonged pre-insemination anoestrus were not observed on the reproductive organs of sexually mature gilts. Our results indicate that most of the culling gilts have reached cyclic ovarian activity. The main reason for culling due to the absence of external estrus manifestations in sexually mature gilts could be inadequate estrus detection technology.
PB  - Elsevier Science Inc, New York
T2  - Theriogenology
T1  - Ovarian activity and uterus organometry in delayed puberty gilts
VL  - 76
IS  - 6
SP  - 1022
EP  - 1026
DO  - 10.1016/j.theriogenology.2011.05.004
ER  - 

@article{
author = "Stančić, Ivan and Stančić, Blagoje and Božić, Aleksandar and Anderson, Robin C. and Harvey, Roger B. and Gvozdić, Dragan",
year = "2011",
abstract = "About 30% of the total number of gilts selected for reproduction at the large breeding farm units in Vojvodina (Republic of Serbia) are culled due to prolonged pre-insemination anoestrus (estrus not detected until 8 mo of age). The aim of this study was to provide the answer to the following question: do the culling gilts reach cyclic ovarian activity at all? One hundred seventy five culled gilts in which external estrus manifestations were not detected by 8 mo of age were sacrificed and their reproductive organs were examined for determination of sexual maturity (ovaries exhibiting pre-ovulatory follicles 8 to 11 mm in diameter, corpora hemorrhagica, corpora lutea and corpora albicantia). Uterine weights and horn length were also determined. Functional ovaries were observed in 107 (61.1%) examined gilts, with 62 animals having one and 45 having two puberty ovarian cycles (57.9% and 42.1%, respectively). Pathomorphological changes which could result in prolonged pre-insemination anoestrus were not observed on the reproductive organs of sexually mature gilts. Our results indicate that most of the culling gilts have reached cyclic ovarian activity. The main reason for culling due to the absence of external estrus manifestations in sexually mature gilts could be inadequate estrus detection technology.",
publisher = "Elsevier Science Inc, New York",
journal = "Theriogenology",
title = "Ovarian activity and uterus organometry in delayed puberty gilts",
volume = "76",
number = "6",
pages = "1022-1026",
doi = "10.1016/j.theriogenology.2011.05.004"
}

Stančić, I., Stančić, B., Božić, A., Anderson, R. C., Harvey, R. B.,& Gvozdić, D.. (2011). Ovarian activity and uterus organometry in delayed puberty gilts. in Theriogenology
Elsevier Science Inc, New York., 76(6), 1022-1026.
https://doi.org/10.1016/j.theriogenology.2011.05.004

Stančić I, Stančić B, Božić A, Anderson RC, Harvey RB, Gvozdić D. Ovarian activity and uterus organometry in delayed puberty gilts. in Theriogenology. 2011;76(6):1022-1026.
doi:10.1016/j.theriogenology.2011.05.004 .

Stančić, Ivan, Stančić, Blagoje, Božić, Aleksandar, Anderson, Robin C., Harvey, Roger B., Gvozdić, Dragan, "Ovarian activity and uterus organometry in delayed puberty gilts" in Theriogenology, 76, no. 6 (2011):1022-1026,
https://doi.org/10.1016/j.theriogenology.2011.05.004 . .

TY  - JOUR
AU  - Stančić, Blagoje
AU  - Radović, I.
AU  - Stančić, Ivan
AU  - Dragin, S.
AU  - Božić, Aleksandar
AU  - Gvozdić, Dragan
PY  - 2010
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/697
AB  - Modern intensive pig production demands an increasing number of insemination doses per ejaculate of genetically superior boars. In order to achieve such a result the possibility of producing insemination doses in both reduced volume and spermatozoa count without decreasing the fertility of sows is studied. In this trial we studied the effect of insemination with reduced volumes of semen (50 mL) and varied spermatozoa count (4, 2 or 1x109). Insemination was performed by the classical (intracervical) or by the new (intrauterine) techniques and the basic fertility parameters (farrowing % and litter size) were measured. The farrowing value decreased with decreasing spermatozoa numbers after intracervical and intrauterine insemination. However, the farrowing value, regardless of spermatozoa numbers, was significantly higher after intrauterine insemination (83.3%, 76.7%, 66.7%) compared to the classical intracervical insemination (73.3%, 66.7% and 50%). Litters size did not vary significantly depending on the applied insemination procedure or spermatozoa number. These results indicate that application of the new intrauterine insemination procedure enables the use of doses with a smaller volume and spermatozoa number, at the same time obtaining a satisfactory farrowing and litter size. This opens the possibility of obtaining a significantly higher number of doses per ejaculate when compared to the classical intracervical insemination procedure. In such a way can be increased significantly the degree of reproductive exploitation of genetically superior boars.
AB  - Savremena intenzivna proizvodnja svinja zahteva dobijanje što većeg broja inseminacionih doza po ejakulatu genetski superiornih nerastova. Radi realizacije ovog cilja, istražuju se mogućnosti pravljenja inseminacionih doza redukovanog volumena i broja spermatozoida, ali da inseminacija ovakvim dozama ne rezultuje smanjenim fertilitetom krmača. U ovom radu je ispitivan uticaj osemenjavanja dozama duplo redukovanog volumena (50 ml) i različitog broja spermatozoida u dozi (4, 2 ili 1x109), posle klasične (intracervikalne) i nove (intrauterine) tehnologije osemenjavanja, na osnovne parametre fertiliteta krmača (% prašenja i veličina legla). Vrednost prašenja je opadala sa smanjenjem broja spermatozoida u dozi, kako posle intracervikalnog, tako i posle intratuterinog osemenjavanja. Međutim, vrednost prašenja je, bez obzira na broj spermatozoida u dozi, bila znatno veća posle intrauterinog (83,3%, 76,7% i 66,7%) u odnosu na klasično intracervikalno osemenjavanje (73,3%, 66,7% i 50%). Veličina legla nije značajno varirala u zavisnosti od primenjene metode osemenjavanja ili broja spermatozoida u dozi. Ovi rezultati ukazuju da je, primenom nove tehnologije intrauterinog osemenjavanja, moguće koristiti doze znatno redukovanog volumena i broja spermatozoida, a da se, pri tome, postignu zadovoljavajuće vrednosti prašenja i veličine legla. Ovo stvara mogućnost dobijanja značajno većeg broja doza po ejakulatu, u odnosu na klasičnu tehnologiju intracervikalnog osemenjavanja. Time se može značajno povećati stepen reproduktivne eksploatacije genetski superiornih nerastova.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Fertility of sows after intracervical or intrauterine insemination with different spermatozoa number in reduced volume doses
T1  - Fertilitet krmača posle intracervikalnog ili intrauterinog osemenjavanja različitim brojem spermatozoida u dozama redukovanog volumena
VL  - 60
IS  - 2-3
SP  - 257
EP  - 262
DO  - 10.2298/AVB1003257S
ER  - 

@article{
author = "Stančić, Blagoje and Radović, I. and Stančić, Ivan and Dragin, S. and Božić, Aleksandar and Gvozdić, Dragan",
year = "2010",
abstract = "Modern intensive pig production demands an increasing number of insemination doses per ejaculate of genetically superior boars. In order to achieve such a result the possibility of producing insemination doses in both reduced volume and spermatozoa count without decreasing the fertility of sows is studied. In this trial we studied the effect of insemination with reduced volumes of semen (50 mL) and varied spermatozoa count (4, 2 or 1x109). Insemination was performed by the classical (intracervical) or by the new (intrauterine) techniques and the basic fertility parameters (farrowing % and litter size) were measured. The farrowing value decreased with decreasing spermatozoa numbers after intracervical and intrauterine insemination. However, the farrowing value, regardless of spermatozoa numbers, was significantly higher after intrauterine insemination (83.3%, 76.7%, 66.7%) compared to the classical intracervical insemination (73.3%, 66.7% and 50%). Litters size did not vary significantly depending on the applied insemination procedure or spermatozoa number. These results indicate that application of the new intrauterine insemination procedure enables the use of doses with a smaller volume and spermatozoa number, at the same time obtaining a satisfactory farrowing and litter size. This opens the possibility of obtaining a significantly higher number of doses per ejaculate when compared to the classical intracervical insemination procedure. In such a way can be increased significantly the degree of reproductive exploitation of genetically superior boars., Savremena intenzivna proizvodnja svinja zahteva dobijanje što većeg broja inseminacionih doza po ejakulatu genetski superiornih nerastova. Radi realizacije ovog cilja, istražuju se mogućnosti pravljenja inseminacionih doza redukovanog volumena i broja spermatozoida, ali da inseminacija ovakvim dozama ne rezultuje smanjenim fertilitetom krmača. U ovom radu je ispitivan uticaj osemenjavanja dozama duplo redukovanog volumena (50 ml) i različitog broja spermatozoida u dozi (4, 2 ili 1x109), posle klasične (intracervikalne) i nove (intrauterine) tehnologije osemenjavanja, na osnovne parametre fertiliteta krmača (% prašenja i veličina legla). Vrednost prašenja je opadala sa smanjenjem broja spermatozoida u dozi, kako posle intracervikalnog, tako i posle intratuterinog osemenjavanja. Međutim, vrednost prašenja je, bez obzira na broj spermatozoida u dozi, bila znatno veća posle intrauterinog (83,3%, 76,7% i 66,7%) u odnosu na klasično intracervikalno osemenjavanje (73,3%, 66,7% i 50%). Veličina legla nije značajno varirala u zavisnosti od primenjene metode osemenjavanja ili broja spermatozoida u dozi. Ovi rezultati ukazuju da je, primenom nove tehnologije intrauterinog osemenjavanja, moguće koristiti doze znatno redukovanog volumena i broja spermatozoida, a da se, pri tome, postignu zadovoljavajuće vrednosti prašenja i veličine legla. Ovo stvara mogućnost dobijanja značajno većeg broja doza po ejakulatu, u odnosu na klasičnu tehnologiju intracervikalnog osemenjavanja. Time se može značajno povećati stepen reproduktivne eksploatacije genetski superiornih nerastova.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Fertility of sows after intracervical or intrauterine insemination with different spermatozoa number in reduced volume doses, Fertilitet krmača posle intracervikalnog ili intrauterinog osemenjavanja različitim brojem spermatozoida u dozama redukovanog volumena",
volume = "60",
number = "2-3",
pages = "257-262",
doi = "10.2298/AVB1003257S"
}

Stančić, B., Radović, I., Stančić, I., Dragin, S., Božić, A.,& Gvozdić, D.. (2010). Fertility of sows after intracervical or intrauterine insemination with different spermatozoa number in reduced volume doses. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 60(2-3), 257-262.
https://doi.org/10.2298/AVB1003257S

Stančić B, Radović I, Stančić I, Dragin S, Božić A, Gvozdić D. Fertility of sows after intracervical or intrauterine insemination with different spermatozoa number in reduced volume doses. in Acta Veterinaria-Beograd. 2010;60(2-3):257-262.
doi:10.2298/AVB1003257S .

Stančić, Blagoje, Radović, I., Stančić, Ivan, Dragin, S., Božić, Aleksandar, Gvozdić, Dragan, "Fertility of sows after intracervical or intrauterine insemination with different spermatozoa number in reduced volume doses" in Acta Veterinaria-Beograd, 60, no. 2-3 (2010):257-262,
https://doi.org/10.2298/AVB1003257S . .