TY  - GEN
AU  - Stojković, Milica
AU  - Blagojević, Jovan
AU  - Gvozdić, Dragan
AU  - Marković, Lazar
AU  - Bošnjaković, Dušan
AU  - Jovanović, Ljubomir
AU  - Kirovski, Danijela
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3806
AB  - Depending on intensity, physical exercise in horses causes various changes in the
parameters of hematological, biochemical, acid-base, and electrolyte status, which can
affect the health and athletic performance of the horse. This study’s objective was to
look at how submaximal exercise at the end of the racing season affected the horses’
hematological, biochemical, acid-base, and electrolyte status markers.
In this study, eight (n=8) trotters, aged 4±2 years, were involved. Venous blood samples
were drawn from each horse by jugular puncture before and after exercise to determine
hematologic, biochemical, acid-base and electrolyte parameters. The submaximal
physical exercise in this study was two intervals of 2,000 m of slow trotting and two
consecutive runs of 500 m at submaximal level. Hematocrit (HCT), red blood cell (RBC) and monocyte count, hemoglobin (HGB)
concentration, aspartate aminotransferase (AST) activity, and glucose concentration
increased significantly after the exercise. Additionally, significant decreases in venous
blood pH, bicarbonate (HCO3
-
) and total CO2 (TCO2) concentration, base excess of
the extracellular fluid (BEecf), and ionized Ca2+ (iCa2+) concentrations were established
after exercise. In contrast, partial pressure of CO2 (pCO2), total concentration of
weak acids (Atot), the anion gap (AG), and total protein and lactate concentrations
were significantly higher after exercise. Considering the significant changes in the
parameters of hematological, biochemical, and acid-base status after submaximal
exercise, determining those parameters would be useful for monitoring the health and
performance of trotters.
PB  - Beograd : Fakultet veterinarske medicine
T2  - Veterinarski Glasnik
T1  - Hematological, biochemical, and acid-base response of trotters to submaximal exercise at the end of the horse racing season
VL  - 78
IS  - 1
SP  - 1
EP  - 14
DO  - https://doi.org/10.2298/VETGL230626002S
ER  - 

@misc{
author = "Stojković, Milica and Blagojević, Jovan and Gvozdić, Dragan and Marković, Lazar and Bošnjaković, Dušan and Jovanović, Ljubomir and Kirovski, Danijela",
year = "2024",
abstract = "Depending on intensity, physical exercise in horses causes various changes in the
parameters of hematological, biochemical, acid-base, and electrolyte status, which can
affect the health and athletic performance of the horse. This study’s objective was to
look at how submaximal exercise at the end of the racing season affected the horses’
hematological, biochemical, acid-base, and electrolyte status markers.
In this study, eight (n=8) trotters, aged 4±2 years, were involved. Venous blood samples
were drawn from each horse by jugular puncture before and after exercise to determine
hematologic, biochemical, acid-base and electrolyte parameters. The submaximal
physical exercise in this study was two intervals of 2,000 m of slow trotting and two
consecutive runs of 500 m at submaximal level. Hematocrit (HCT), red blood cell (RBC) and monocyte count, hemoglobin (HGB)
concentration, aspartate aminotransferase (AST) activity, and glucose concentration
increased significantly after the exercise. Additionally, significant decreases in venous
blood pH, bicarbonate (HCO3
-
) and total CO2 (TCO2) concentration, base excess of
the extracellular fluid (BEecf), and ionized Ca2+ (iCa2+) concentrations were established
after exercise. In contrast, partial pressure of CO2 (pCO2), total concentration of
weak acids (Atot), the anion gap (AG), and total protein and lactate concentrations
were significantly higher after exercise. Considering the significant changes in the
parameters of hematological, biochemical, and acid-base status after submaximal
exercise, determining those parameters would be useful for monitoring the health and
performance of trotters.",
publisher = "Beograd : Fakultet veterinarske medicine",
journal = "Veterinarski Glasnik",
title = "Hematological, biochemical, and acid-base response of trotters to submaximal exercise at the end of the horse racing season",
volume = "78",
number = "1",
pages = "1-14",
doi = "https://doi.org/10.2298/VETGL230626002S"
}

Stojković, M., Blagojević, J., Gvozdić, D., Marković, L., Bošnjaković, D., Jovanović, L.,& Kirovski, D.. (2024). Hematological, biochemical, and acid-base response of trotters to submaximal exercise at the end of the horse racing season. in Veterinarski Glasnik
Beograd : Fakultet veterinarske medicine., 78(1), 1-14.
https://doi.org/https://doi.org/10.2298/VETGL230626002S

Stojković M, Blagojević J, Gvozdić D, Marković L, Bošnjaković D, Jovanović L, Kirovski D. Hematological, biochemical, and acid-base response of trotters to submaximal exercise at the end of the horse racing season. in Veterinarski Glasnik. 2024;78(1):1-14.
doi:https://doi.org/10.2298/VETGL230626002S .

Stojković, Milica, Blagojević, Jovan, Gvozdić, Dragan, Marković, Lazar, Bošnjaković, Dušan, Jovanović, Ljubomir, Kirovski, Danijela, "Hematological, biochemical, and acid-base response of trotters to submaximal exercise at the end of the horse racing season" in Veterinarski Glasnik, 78, no. 1 (2024):1-14,
https://doi.org/https://doi.org/10.2298/VETGL230626002S . .

TY  - CONF
AU  - Fratrić, Natalija
AU  - Gvozdić, Dragan
AU  - Nenadović, Katarina
AU  - Maletić, Milan
AU  - Bugarski, Dejan
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3213
AB  - Razumevanje uslova tokom intrauterinog razvoja koja utiču na zdravlje i rast
teladi može pomoći u osmišljavanju prakse menadžmenta koja pozitivno utiče na
razvoj novorođenčadi i buduće proizvodne rezultate krava. Više faktora majke je
dokazano da utiče na epigenom fetusa, kao što su ishrana, metabolički status, toksini
(pesticidi ili herbicidi), socijalna interakcija i stresori sredine ( na pr., toplotni stres).
Oksidativni stres je takođe važan faktor koji pored promena u ekspresiji gena i
proteina, može doprineti stvaranju neadekvatnog okruženja za razvoj fetusa usled
promena u funkciji metabolizma majke. Period kasne gestacije je period najvećeg
fetalnog rasta i najbrže proliferacije imunskih ćelija fetusa goveda. Stoga suboptimalni
uslovi u predhodnim I ovom periodu gestacije mogu dovesti do promena u strukturi i
funkciji tkiva I organa koje su u vezi sa metabolizmom, rastom I većom osetljivosti na
bolesti teladi a održavaju se I na produktivnost kao odrasle jedinke.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023
T1  - Uticaj stresa tokom kasne gestacije na rast, zdravlje teladi mlečnih krava i proizvodne rezultate kao odrasle jedinke
SP  - 53
EP  - 61
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3213
ER  - 

@conference{
author = "Fratrić, Natalija and Gvozdić, Dragan and Nenadović, Katarina and Maletić, Milan and Bugarski, Dejan",
year = "2023",
abstract = "Razumevanje uslova tokom intrauterinog razvoja koja utiču na zdravlje i rast
teladi može pomoći u osmišljavanju prakse menadžmenta koja pozitivno utiče na
razvoj novorođenčadi i buduće proizvodne rezultate krava. Više faktora majke je
dokazano da utiče na epigenom fetusa, kao što su ishrana, metabolički status, toksini
(pesticidi ili herbicidi), socijalna interakcija i stresori sredine ( na pr., toplotni stres).
Oksidativni stres je takođe važan faktor koji pored promena u ekspresiji gena i
proteina, može doprineti stvaranju neadekvatnog okruženja za razvoj fetusa usled
promena u funkciji metabolizma majke. Period kasne gestacije je period najvećeg
fetalnog rasta i najbrže proliferacije imunskih ćelija fetusa goveda. Stoga suboptimalni
uslovi u predhodnim I ovom periodu gestacije mogu dovesti do promena u strukturi i
funkciji tkiva I organa koje su u vezi sa metabolizmom, rastom I većom osetljivosti na
bolesti teladi a održavaju se I na produktivnost kao odrasle jedinke.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023",
title = "Uticaj stresa tokom kasne gestacije na rast, zdravlje teladi mlečnih krava i proizvodne rezultate kao odrasle jedinke",
pages = "53-61",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3213"
}

Fratrić, N., Gvozdić, D., Nenadović, K., Maletić, M.,& Bugarski, D.. (2023). Uticaj stresa tokom kasne gestacije na rast, zdravlje teladi mlečnih krava i proizvodne rezultate kao odrasle jedinke. in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023
Beograd : Srpsko veterinarsko društvo., 53-61.
https://hdl.handle.net/21.15107/rcub_veterinar_3213

Fratrić N, Gvozdić D, Nenadović K, Maletić M, Bugarski D. Uticaj stresa tokom kasne gestacije na rast, zdravlje teladi mlečnih krava i proizvodne rezultate kao odrasle jedinke. in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023. 2023;:53-61.
https://hdl.handle.net/21.15107/rcub_veterinar_3213 .

Fratrić, Natalija, Gvozdić, Dragan, Nenadović, Katarina, Maletić, Milan, Bugarski, Dejan, "Uticaj stresa tokom kasne gestacije na rast, zdravlje teladi mlečnih krava i proizvodne rezultate kao odrasle jedinke" in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023 (2023):53-61,
https://hdl.handle.net/21.15107/rcub_veterinar_3213 .

TY  - CONF
AU  - Fratrić, Natalija
AU  - Gvozdić, Dragan
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3280
AB  - Mikrobiom goveda predstavlja dinamičan ekosistem koji podleže značajnim
fluktuacijama tokom celog života jedinke. Sastav mikrobioma varira u zavisnosti od faktora domaćina i različitih fizičko-hemijskih osobina sredine koju naseljava. Mikrobiom kod goveda čine veoma veliki broj vrsta mikroorganizama koji žive
i koegzistiraju u/na prirodnom domaćinu, a poremećaji njihovih populacija mogu
imati štetan efekat na zdravlje. Ravnoteža rasta mikrobne populacije može biti poremećena u toku bolesti usled smanjenja istih, ili pojave različitih vrsta mikroba
što dovodi do disbioze. Disbioza može izazvati ili pogoršati više bolesti kod goveda. Mogući izvori mikroflore u reproduktivnom traktu su prenos bakterija iz creva
(feces), iz spoljašnje sredine (prostirka, koža), najčešće vaginalnim putem, kao i
hematogenim putem. Značajne razlike su ustanovljene u mikrobiomu reproduktivnog trakta goveda u zavisnosti od rase, anatomske regije i fiziološkog stanja. Otkriveno je da je mikrobiom reproduktivnog trakta majke povezan sa ishodom graviditeta i kasnijim ranim životom potomstva.
Osim tokom teljenja, patogeni mikroorganizmi mogu imati pristup reproduktivnim organima tokom parenja i veštačkog osemenjavanja. Invazija patogenih
mikroba izaziva inflamatorni odgovor i uništavanje integriteta endometrijuma, što
je nepovoljno za transport spermatozoida i razvoj embriona. Promena komensalnih bakterija unutar mlečne žlezde ima štetan efekat na homeostazu mlečne žlezde. Poznavanje mikrobioma reproduktivnog trakta goveda može imati veliki značaj za uspešnu reprodukciju goveda, ishod terapijskih procedura i zdravlje novorođenih teladi.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 14. Naučni simpozijum Reprodukcija životinja, Divčibare, 12 - 15. oktobar 2023
T1  - Mikrobiom kod zdravih goveda i poremećaji (disbioza) kod metritisa, endometritisa i mastitisa
SP  - 37
EP  - 52
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3280
ER  - 

@conference{
author = "Fratrić, Natalija and Gvozdić, Dragan",
year = "2023",
abstract = "Mikrobiom goveda predstavlja dinamičan ekosistem koji podleže značajnim
fluktuacijama tokom celog života jedinke. Sastav mikrobioma varira u zavisnosti od faktora domaćina i različitih fizičko-hemijskih osobina sredine koju naseljava. Mikrobiom kod goveda čine veoma veliki broj vrsta mikroorganizama koji žive
i koegzistiraju u/na prirodnom domaćinu, a poremećaji njihovih populacija mogu
imati štetan efekat na zdravlje. Ravnoteža rasta mikrobne populacije može biti poremećena u toku bolesti usled smanjenja istih, ili pojave različitih vrsta mikroba
što dovodi do disbioze. Disbioza može izazvati ili pogoršati više bolesti kod goveda. Mogući izvori mikroflore u reproduktivnom traktu su prenos bakterija iz creva
(feces), iz spoljašnje sredine (prostirka, koža), najčešće vaginalnim putem, kao i
hematogenim putem. Značajne razlike su ustanovljene u mikrobiomu reproduktivnog trakta goveda u zavisnosti od rase, anatomske regije i fiziološkog stanja. Otkriveno je da je mikrobiom reproduktivnog trakta majke povezan sa ishodom graviditeta i kasnijim ranim životom potomstva.
Osim tokom teljenja, patogeni mikroorganizmi mogu imati pristup reproduktivnim organima tokom parenja i veštačkog osemenjavanja. Invazija patogenih
mikroba izaziva inflamatorni odgovor i uništavanje integriteta endometrijuma, što
je nepovoljno za transport spermatozoida i razvoj embriona. Promena komensalnih bakterija unutar mlečne žlezde ima štetan efekat na homeostazu mlečne žlezde. Poznavanje mikrobioma reproduktivnog trakta goveda može imati veliki značaj za uspešnu reprodukciju goveda, ishod terapijskih procedura i zdravlje novorođenih teladi.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "14. Naučni simpozijum Reprodukcija životinja, Divčibare, 12 - 15. oktobar 2023",
title = "Mikrobiom kod zdravih goveda i poremećaji (disbioza) kod metritisa, endometritisa i mastitisa",
pages = "37-52",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3280"
}

Fratrić, N.,& Gvozdić, D.. (2023). Mikrobiom kod zdravih goveda i poremećaji (disbioza) kod metritisa, endometritisa i mastitisa. in 14. Naučni simpozijum Reprodukcija životinja, Divčibare, 12 - 15. oktobar 2023
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 37-52.
https://hdl.handle.net/21.15107/rcub_veterinar_3280

Fratrić N, Gvozdić D. Mikrobiom kod zdravih goveda i poremećaji (disbioza) kod metritisa, endometritisa i mastitisa. in 14. Naučni simpozijum Reprodukcija životinja, Divčibare, 12 - 15. oktobar 2023. 2023;:37-52.
https://hdl.handle.net/21.15107/rcub_veterinar_3280 .

Fratrić, Natalija, Gvozdić, Dragan, "Mikrobiom kod zdravih goveda i poremećaji (disbioza) kod metritisa, endometritisa i mastitisa" in 14. Naučni simpozijum Reprodukcija životinja, Divčibare, 12 - 15. oktobar 2023 (2023):37-52,
https://hdl.handle.net/21.15107/rcub_veterinar_3280 .

TY  - CONF
AU  - Fratrić, Natalija
AU  - Kovačić, Marijana
AU  - Gvozdić, Dragan
AU  - Marković, Dragana
AU  - Drvenica, Ivana
AU  - Maslovarić, Irina
AU  - Ilić, Vesna
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3331
PB  - German Veterinary Medical Society
C3  - European Buiatrics Congress and ECBHM Jubilee Symposium 2023, Berlin, Germany, August 24 - 26, 2023
T1  - Rivanol soluble blood serum IgG in calf bronchopneumonia
SP  - 251
EP  - 252
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3331
ER  - 

@conference{
author = "Fratrić, Natalija and Kovačić, Marijana and Gvozdić, Dragan and Marković, Dragana and Drvenica, Ivana and Maslovarić, Irina and Ilić, Vesna",
year = "2023",
publisher = "German Veterinary Medical Society",
journal = "European Buiatrics Congress and ECBHM Jubilee Symposium 2023, Berlin, Germany, August 24 - 26, 2023",
title = "Rivanol soluble blood serum IgG in calf bronchopneumonia",
pages = "251-252",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3331"
}

Fratrić, N., Kovačić, M., Gvozdić, D., Marković, D., Drvenica, I., Maslovarić, I.,& Ilić, V.. (2023). Rivanol soluble blood serum IgG in calf bronchopneumonia. in European Buiatrics Congress and ECBHM Jubilee Symposium 2023, Berlin, Germany, August 24 - 26, 2023
German Veterinary Medical Society., 251-252.
https://hdl.handle.net/21.15107/rcub_veterinar_3331

Fratrić N, Kovačić M, Gvozdić D, Marković D, Drvenica I, Maslovarić I, Ilić V. Rivanol soluble blood serum IgG in calf bronchopneumonia. in European Buiatrics Congress and ECBHM Jubilee Symposium 2023, Berlin, Germany, August 24 - 26, 2023. 2023;:251-252.
https://hdl.handle.net/21.15107/rcub_veterinar_3331 .

Fratrić, Natalija, Kovačić, Marijana, Gvozdić, Dragan, Marković, Dragana, Drvenica, Ivana, Maslovarić, Irina, Ilić, Vesna, "Rivanol soluble blood serum IgG in calf bronchopneumonia" in European Buiatrics Congress and ECBHM Jubilee Symposium 2023, Berlin, Germany, August 24 - 26, 2023 (2023):251-252,
https://hdl.handle.net/21.15107/rcub_veterinar_3331 .

TY  - JOUR
AU  - Kopilović, Aleksandar
AU  - Gvozdić, Dragan
AU  - Radaković, Milena
AU  - Spariosu, Kristina
AU  - Andrić, Nenad
AU  - Francuski Andrić, Jelena
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3442
AB  - In veterinary medicine, knowledge about hematologic ratios (neutrophil-to-lymphocyte
ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume-to-platelet
ratio (MPV/PLT)) is limited, particularly in cats. While the roles of these ratios have
been proven in oncology, systemic inflammation with or without systemic inflammatory
response syndrome (SIRS), and sepsis, information is lacking about their alterations in
non-septic effusions, like feline infectious peritonitis (FIP).
This study aimed to describe whether NLR, PLR, and MPV/PLT were changed and
whether they correlated with routine hematologic and biochemical parameters in 16
cats with non-septic effusions, highly suspected to be the effusive form of FIP without
SIRS, compared to nine clinically healthy cats.
The NLR was calculated as the absolute count of neutrophils divided by the absolute
count of lymphocytes, PLR by calculating the absolute platelet divided by the absolute
lymphocyte count, and MPV/PLT by dividing mean platelet volume by absolute platelet
count.
The NLR, MPV, and MPV/PLT ratios were higher in cats with non-septic effusions
suspected to be FIP, but PLR did not differ, when compared to healthy cats. Correlation analysis did not show any association between the selected ratios and hematological and
biochemical parameters.
In the absence of leukocytosis, increased NLR could help us to confirm the presence
of systemic inflammation in cats with non-septic effusions indicative of FIP. However,
a high MPV/PLT ratio should be interpreted with caution, especially in cats.
PB  - Beograd : Fakultet veterinarske medicine
T2  - Veterinarski Glasnik
T1  - Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis
VL  - 77
IS  - 2
SP  - 164
EP  - 175
DO  - 10.2298/VETGL230710008K
ER  - 

@article{
author = "Kopilović, Aleksandar and Gvozdić, Dragan and Radaković, Milena and Spariosu, Kristina and Andrić, Nenad and Francuski Andrić, Jelena",
year = "2023",
abstract = "In veterinary medicine, knowledge about hematologic ratios (neutrophil-to-lymphocyte
ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume-to-platelet
ratio (MPV/PLT)) is limited, particularly in cats. While the roles of these ratios have
been proven in oncology, systemic inflammation with or without systemic inflammatory
response syndrome (SIRS), and sepsis, information is lacking about their alterations in
non-septic effusions, like feline infectious peritonitis (FIP).
This study aimed to describe whether NLR, PLR, and MPV/PLT were changed and
whether they correlated with routine hematologic and biochemical parameters in 16
cats with non-septic effusions, highly suspected to be the effusive form of FIP without
SIRS, compared to nine clinically healthy cats.
The NLR was calculated as the absolute count of neutrophils divided by the absolute
count of lymphocytes, PLR by calculating the absolute platelet divided by the absolute
lymphocyte count, and MPV/PLT by dividing mean platelet volume by absolute platelet
count.
The NLR, MPV, and MPV/PLT ratios were higher in cats with non-septic effusions
suspected to be FIP, but PLR did not differ, when compared to healthy cats. Correlation analysis did not show any association between the selected ratios and hematological and
biochemical parameters.
In the absence of leukocytosis, increased NLR could help us to confirm the presence
of systemic inflammation in cats with non-septic effusions indicative of FIP. However,
a high MPV/PLT ratio should be interpreted with caution, especially in cats.",
publisher = "Beograd : Fakultet veterinarske medicine",
journal = "Veterinarski Glasnik",
title = "Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis",
volume = "77",
number = "2",
pages = "164-175",
doi = "10.2298/VETGL230710008K"
}

Kopilović, A., Gvozdić, D., Radaković, M., Spariosu, K., Andrić, N.,& Francuski Andrić, J.. (2023). Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis. in Veterinarski Glasnik
Beograd : Fakultet veterinarske medicine., 77(2), 164-175.
https://doi.org/10.2298/VETGL230710008K

Kopilović A, Gvozdić D, Radaković M, Spariosu K, Andrić N, Francuski Andrić J. Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis. in Veterinarski Glasnik. 2023;77(2):164-175.
doi:10.2298/VETGL230710008K .

Kopilović, Aleksandar, Gvozdić, Dragan, Radaković, Milena, Spariosu, Kristina, Andrić, Nenad, Francuski Andrić, Jelena, "Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis" in Veterinarski Glasnik, 77, no. 2 (2023):164-175,
https://doi.org/10.2298/VETGL230710008K . .

TY  - CONF
AU  - Fratrić, Natalija
AU  - Gvozdić, Dragan
AU  - Vakanjac, Slobodanka
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3182
AB  - Uzgoj junica za remont stada na farmamma mlečnih krava predstavlja značajan
trošak, pri čemu je reproduktivna efikasnost jedan od glavnih faktora koji utiču
na ukupne troškove uzgoja. Smanjen prirast kod teladi, smanjena proizvodnja
mleka kod krava koje su kao telad imale hronične bolesti, širenje zaraznih bolesti
sa teladi na odrasle krave, povećani veterinarski troškovi, ograničena mogućnost
genetske selekcije zbog visokog mortaliteta životinja za obrt stada, negativno utiče
na produktivnost. Najveći morbiditet i mortalitet se javlja kod teladi pre odbijanja.
Mnoge bolesti novorođenih teladi mogu se kontrolisati dobro osmišljenim programima
upravljanja zdravljem, koji definišu brigu i smeštaj majke tokom peripartalnog
perioda, standardne operativne procedure kod teljenja i primenu odgovarajućih
preventivnih mera (uključujući programe pravilne ishrane) za novorođenu
telad. Zdrava telad mogu postići stopu rasta koja im omogućava polnu zrelost u
starosti od 13 do 15 meseci što se pozitivno odražava na produktivnost celokupnog
stada mlečnih krava.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022
T1  - Glavni zdravstveni problemi kod teladi u neonatalnom periodu
SP  - 17
EP  - 29
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3182
ER  - 

@conference{
author = "Fratrić, Natalija and Gvozdić, Dragan and Vakanjac, Slobodanka",
year = "2022",
abstract = "Uzgoj junica za remont stada na farmamma mlečnih krava predstavlja značajan
trošak, pri čemu je reproduktivna efikasnost jedan od glavnih faktora koji utiču
na ukupne troškove uzgoja. Smanjen prirast kod teladi, smanjena proizvodnja
mleka kod krava koje su kao telad imale hronične bolesti, širenje zaraznih bolesti
sa teladi na odrasle krave, povećani veterinarski troškovi, ograničena mogućnost
genetske selekcije zbog visokog mortaliteta životinja za obrt stada, negativno utiče
na produktivnost. Najveći morbiditet i mortalitet se javlja kod teladi pre odbijanja.
Mnoge bolesti novorođenih teladi mogu se kontrolisati dobro osmišljenim programima
upravljanja zdravljem, koji definišu brigu i smeštaj majke tokom peripartalnog
perioda, standardne operativne procedure kod teljenja i primenu odgovarajućih
preventivnih mera (uključujući programe pravilne ishrane) za novorođenu
telad. Zdrava telad mogu postići stopu rasta koja im omogućava polnu zrelost u
starosti od 13 do 15 meseci što se pozitivno odražava na produktivnost celokupnog
stada mlečnih krava.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022",
title = "Glavni zdravstveni problemi kod teladi u neonatalnom periodu",
pages = "17-29",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3182"
}

Fratrić, N., Gvozdić, D.,& Vakanjac, S.. (2022). Glavni zdravstveni problemi kod teladi u neonatalnom periodu. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 17-29.
https://hdl.handle.net/21.15107/rcub_veterinar_3182

Fratrić N, Gvozdić D, Vakanjac S. Glavni zdravstveni problemi kod teladi u neonatalnom periodu. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022. 2022;:17-29.
https://hdl.handle.net/21.15107/rcub_veterinar_3182 .

Fratrić, Natalija, Gvozdić, Dragan, Vakanjac, Slobodanka, "Glavni zdravstveni problemi kod teladi u neonatalnom periodu" in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022 (2022):17-29,
https://hdl.handle.net/21.15107/rcub_veterinar_3182 .

TY  - CONF
AU  - Milanović, Svetlana
AU  - Valčić, Olivera
AU  - Gvozdić, Dragan
AU  - Jovanović, Ivan B.
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2418
AB  - U intenzivnoj stočarskoj proizvodnji, od muznih krava se očekuje maksimalno iskorišćavanje genetskog potencijala i što veći prinos
mleka. Najveći izazov u tom smislu predstavlja peripartalni period koji obuhvata tri nedelje pre i tri nedelje posle partusa. Tada se u organizmu krave dešavaju velike hormonske, metaboličke i imunološke
promene. Mnogi metabolički poremećaji koji su karakteristični za ovaj
period, posledica su neizbalansirane ishrane i nepravilne pripreme jedinke za ulazak u intenzivnu laktaciju. Masna jetra, ketoza, dislokacija
sirišta i puerperalna pareza predstavljaju glavne poremećaje karakteristične za ovaj period, a oksidativni stres može imati veliku ulogu u
njihovoj pojavi. Osim navedenih poremećaja, zaostajanje posteljice i
pojava mastitisa, mogu takođe biti u vezi sa oksidativnim stresom. U
ovom radu ćemo analizirati podatke iz naših istraživanja i dostupne literature i pokušati da objasnimo ulogu oksidativnog stresa u peripartalnom periodu, sa posebnim osvrtom na primenu antioksidanasa u cilju preveniranja pojave ili posledica metaboličkih poremećaja.
AB  - In intensive production, dairy cows are expected to make the most of their genetic
potential and maximize milk yield. The biggest challenge in this regard is the peripartal
period, which includes three weeks before and three weeks after parturition. In that interval
major hormonal, metabolic and immune changes occur in the cow’s body. Many metabolic
disorders that are characteristic of this period are the result of an unbalanced diet and
improper preparation of the individual to enter intensive lactation. Fatty liver, ketosis,
dislocation of the abomasum, and puerperal paresis are the main disorders which are
characteristic of this period, and oxidative stress can play a major role in their occurrence.
In addition to these disorders, retained placenta and mastitis may also be related to
oxidative stress. In this paper, we will analyze the data from our research and the available literature, and try to explain the role of oxidative stress in the peripartal period, with special
emphasis on the use of antioxidants in the prevention of the occurrence or consequences
of metabolic disorders.
PB  - Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - Zbornik radova - XLIII seminar inovacija znanja veterinara
T1  - Oksidativni stres kod krava u peripartalnom periodu – uzrok ili posledica metaboličkih poremećaja
T1  - Oxidative stress in cows in the peripartal period – cause or consequence of metabolic disorders
SP  - 67
EP  - 78
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2418
ER  - 

@conference{
author = "Milanović, Svetlana and Valčić, Olivera and Gvozdić, Dragan and Jovanović, Ivan B.",
year = "2022",
abstract = "U intenzivnoj stočarskoj proizvodnji, od muznih krava se očekuje maksimalno iskorišćavanje genetskog potencijala i što veći prinos
mleka. Najveći izazov u tom smislu predstavlja peripartalni period koji obuhvata tri nedelje pre i tri nedelje posle partusa. Tada se u organizmu krave dešavaju velike hormonske, metaboličke i imunološke
promene. Mnogi metabolički poremećaji koji su karakteristični za ovaj
period, posledica su neizbalansirane ishrane i nepravilne pripreme jedinke za ulazak u intenzivnu laktaciju. Masna jetra, ketoza, dislokacija
sirišta i puerperalna pareza predstavljaju glavne poremećaje karakteristične za ovaj period, a oksidativni stres može imati veliku ulogu u
njihovoj pojavi. Osim navedenih poremećaja, zaostajanje posteljice i
pojava mastitisa, mogu takođe biti u vezi sa oksidativnim stresom. U
ovom radu ćemo analizirati podatke iz naših istraživanja i dostupne literature i pokušati da objasnimo ulogu oksidativnog stresa u peripartalnom periodu, sa posebnim osvrtom na primenu antioksidanasa u cilju preveniranja pojave ili posledica metaboličkih poremećaja., In intensive production, dairy cows are expected to make the most of their genetic
potential and maximize milk yield. The biggest challenge in this regard is the peripartal
period, which includes three weeks before and three weeks after parturition. In that interval
major hormonal, metabolic and immune changes occur in the cow’s body. Many metabolic
disorders that are characteristic of this period are the result of an unbalanced diet and
improper preparation of the individual to enter intensive lactation. Fatty liver, ketosis,
dislocation of the abomasum, and puerperal paresis are the main disorders which are
characteristic of this period, and oxidative stress can play a major role in their occurrence.
In addition to these disorders, retained placenta and mastitis may also be related to
oxidative stress. In this paper, we will analyze the data from our research and the available literature, and try to explain the role of oxidative stress in the peripartal period, with special
emphasis on the use of antioxidants in the prevention of the occurrence or consequences
of metabolic disorders.",
publisher = "Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "Zbornik radova - XLIII seminar inovacija znanja veterinara",
title = "Oksidativni stres kod krava u peripartalnom periodu – uzrok ili posledica metaboličkih poremećaja, Oxidative stress in cows in the peripartal period – cause or consequence of metabolic disorders",
pages = "67-78",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2418"
}

Milanović, S., Valčić, O., Gvozdić, D.,& Jovanović, I. B.. (2022). Oksidativni stres kod krava u peripartalnom periodu – uzrok ili posledica metaboličkih poremećaja. in Zbornik radova - XLIII seminar inovacija znanja veterinara
Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 67-78.
https://hdl.handle.net/21.15107/rcub_veterinar_2418

Milanović S, Valčić O, Gvozdić D, Jovanović IB. Oksidativni stres kod krava u peripartalnom periodu – uzrok ili posledica metaboličkih poremećaja. in Zbornik radova - XLIII seminar inovacija znanja veterinara. 2022;:67-78.
https://hdl.handle.net/21.15107/rcub_veterinar_2418 .

Milanović, Svetlana, Valčić, Olivera, Gvozdić, Dragan, Jovanović, Ivan B., "Oksidativni stres kod krava u peripartalnom periodu – uzrok ili posledica metaboličkih poremećaja" in Zbornik radova - XLIII seminar inovacija znanja veterinara (2022):67-78,
https://hdl.handle.net/21.15107/rcub_veterinar_2418 .

TY  - JOUR
AU  - Ivana, Drvenica
AU  - Stojić, Milica
AU  - Fratrić, Natalija
AU  - Kovačić, Marijana
AU  - Grujić-Milanović, Jelica
AU  - Vejnović, Branislav
AU  - Marković, Dragana
AU  - Gvozdić, Dragan
AU  - Ilić, Vesna
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2646
AB  - Redox imbalance in peripartum period influences health of dairy cows and their foetus and,
through the colostrum, health of new-born calves. Oxidative stress in cattle can be suppressed
by dietary supplementation with natural minerals, and we investigated the effect of supplementation with organically modified clinoptilolite on redox status parameters in healthy pregnant
primiparous dairy cows. Holstein cows were randomly assigned to receive daily oral drenching,
with 1 L of water containing either 0 g/L (n ¼ 14; control group) or 150 g/L of clinoptilolite (n ¼ 17; supplemented group). Treatment lasted from 24 ± 4 days prior to parturition until 2 days postpartum (pp). Blood samples were collected on days 24 ± 4 (–24 D) and 4 ± 2 (–4 D) prior to
parturition and on days 1 (þ1 D), 2 (þ2 D), and 7 (þ7 D) pp, and colostrum were collected at 2,
12, 24 and 36 h pp. Total antioxidant capacity, lipid peroxides, and advanced oxidation protein
products (AOPP) levels were determined in peripheral blood plasma, erythrocytes, and colostrum
whey. The concentration of antioxidants in the peripheral blood of supplemented cows was
increased by 41% and 19% on (þ2 D) and (þ7 D), respectively, while the concentration of lipid
peroxides on (þ7 D) was lowered by 57% compared with the control group. In addition, this
supplementation increased erythrocyte AOPP level on (–4 D) 61%) and colostral lipid peroxides
level (90%) at 24 h pp. The results of this study showed that applied short-term supplementation
with clinoptilolite influences redox homeostasis and may contribute to effective adaptation of
primiparous cows to redox imbalance in the peripartum period.
PB  - Taylor and Francis
T2  - Italian Journal of Animal Science
T1  - Oral supplementation with organically modified clinoptilolite during prepartum period influences the redox status of peripheral blood and colostrum of primiparous dairy cows
VL  - 21
IS  - 1
SP  - 847
EP  - 858
DO  - 10.1080/1828051X.2022.2070034
ER  - 

@article{
author = "Ivana, Drvenica and Stojić, Milica and Fratrić, Natalija and Kovačić, Marijana and Grujić-Milanović, Jelica and Vejnović, Branislav and Marković, Dragana and Gvozdić, Dragan and Ilić, Vesna",
year = "2022",
abstract = "Redox imbalance in peripartum period influences health of dairy cows and their foetus and,
through the colostrum, health of new-born calves. Oxidative stress in cattle can be suppressed
by dietary supplementation with natural minerals, and we investigated the effect of supplementation with organically modified clinoptilolite on redox status parameters in healthy pregnant
primiparous dairy cows. Holstein cows were randomly assigned to receive daily oral drenching,
with 1 L of water containing either 0 g/L (n ¼ 14; control group) or 150 g/L of clinoptilolite (n ¼ 17; supplemented group). Treatment lasted from 24 ± 4 days prior to parturition until 2 days postpartum (pp). Blood samples were collected on days 24 ± 4 (–24 D) and 4 ± 2 (–4 D) prior to
parturition and on days 1 (þ1 D), 2 (þ2 D), and 7 (þ7 D) pp, and colostrum were collected at 2,
12, 24 and 36 h pp. Total antioxidant capacity, lipid peroxides, and advanced oxidation protein
products (AOPP) levels were determined in peripheral blood plasma, erythrocytes, and colostrum
whey. The concentration of antioxidants in the peripheral blood of supplemented cows was
increased by 41% and 19% on (þ2 D) and (þ7 D), respectively, while the concentration of lipid
peroxides on (þ7 D) was lowered by 57% compared with the control group. In addition, this
supplementation increased erythrocyte AOPP level on (–4 D) 61%) and colostral lipid peroxides
level (90%) at 24 h pp. The results of this study showed that applied short-term supplementation
with clinoptilolite influences redox homeostasis and may contribute to effective adaptation of
primiparous cows to redox imbalance in the peripartum period.",
publisher = "Taylor and Francis",
journal = "Italian Journal of Animal Science",
title = "Oral supplementation with organically modified clinoptilolite during prepartum period influences the redox status of peripheral blood and colostrum of primiparous dairy cows",
volume = "21",
number = "1",
pages = "847-858",
doi = "10.1080/1828051X.2022.2070034"
}

Ivana, D., Stojić, M., Fratrić, N., Kovačić, M., Grujić-Milanović, J., Vejnović, B., Marković, D., Gvozdić, D.,& Ilić, V.. (2022). Oral supplementation with organically modified clinoptilolite during prepartum period influences the redox status of peripheral blood and colostrum of primiparous dairy cows. in Italian Journal of Animal Science
Taylor and Francis., 21(1), 847-858.
https://doi.org/10.1080/1828051X.2022.2070034

Ivana D, Stojić M, Fratrić N, Kovačić M, Grujić-Milanović J, Vejnović B, Marković D, Gvozdić D, Ilić V. Oral supplementation with organically modified clinoptilolite during prepartum period influences the redox status of peripheral blood and colostrum of primiparous dairy cows. in Italian Journal of Animal Science. 2022;21(1):847-858.
doi:10.1080/1828051X.2022.2070034 .

Ivana, Drvenica, Stojić, Milica, Fratrić, Natalija, Kovačić, Marijana, Grujić-Milanović, Jelica, Vejnović, Branislav, Marković, Dragana, Gvozdić, Dragan, Ilić, Vesna, "Oral supplementation with organically modified clinoptilolite during prepartum period influences the redox status of peripheral blood and colostrum of primiparous dairy cows" in Italian Journal of Animal Science, 21, no. 1 (2022):847-858,
https://doi.org/10.1080/1828051X.2022.2070034 . .

TY  - CONF
AU  - Šuluburić, Adam
AU  - Gvozdić, Dragan
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3183
AB  - Razvijanje novih programa indukcije i sinhronizacije estrusa u mlečnom govedarstvu
je proces zasnovan na zavisnosti uspeha reprodukcije od nivoa reproduktivnih
hormona. U osnovi većine protokola sinhronizacije je primena prostaglandina
F2α tj.malnipulacija žutim telom. Sve se više posvećuje pažnja ulozi
progesterona pre i tokom procesa sinhronizacije, pa sve do konačne potvrde graviditeta
dva meseca nakon oplođenja. Razvoj žutog tela i koncentracija progesterona
u vezi su sa reproduktivnim ishodom tj. povratkom u estrus, embrionalnim
mortalitetom i graviditetom, čime se progesteron pozitivnom spregom dovodi u
vezu sa intenzivnom proizvodnjom proteina ranog graviditeta (EEP’s), interferona
Tau (IFNτ) i glikoproteina graviditeta (PAG’s). Lutealna dinamika predstavlja
bitan činilac, bilo da je to stvaranje uslova tokom sinhronizacije za ambijent sa niskom
koncentracijom, ili po oplođenju sa visokom koncentracijom progesterona,
rezultirajući boljim reproduktivnim pokazateljima stanja farme. Visoka koncentacija
progesterona u mleku tokom lutealne faze omogućava lako praćenje progesterona
tokom sinhronizacije, kao i u danima nakon oplodnje, omogućavajući menađžmentu
farme izbor odgovarajuće reproduktivne strategije. Detekcija progesterona
metodom fluorescentne polarizacije (FPA) se izdvaja kao praktičan i lako
izvodljiv test koji daje uvid u koncentracije progesterona u mleku u različitim reproduktivnim
fazama krave i otvara mogućnost pravovremenog intervenisanja u
okviru programa za poboljšanje plodnosti na farmi.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022
T1  - Indukcija i sinhronizacija estrusa kod krava i test za ranu dijagnostiku graviditeta
SP  - 37
EP  - 46
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3183
ER  - 

@conference{
author = "Šuluburić, Adam and Gvozdić, Dragan",
year = "2022",
abstract = "Razvijanje novih programa indukcije i sinhronizacije estrusa u mlečnom govedarstvu
je proces zasnovan na zavisnosti uspeha reprodukcije od nivoa reproduktivnih
hormona. U osnovi većine protokola sinhronizacije je primena prostaglandina
F2α tj.malnipulacija žutim telom. Sve se više posvećuje pažnja ulozi
progesterona pre i tokom procesa sinhronizacije, pa sve do konačne potvrde graviditeta
dva meseca nakon oplođenja. Razvoj žutog tela i koncentracija progesterona
u vezi su sa reproduktivnim ishodom tj. povratkom u estrus, embrionalnim
mortalitetom i graviditetom, čime se progesteron pozitivnom spregom dovodi u
vezu sa intenzivnom proizvodnjom proteina ranog graviditeta (EEP’s), interferona
Tau (IFNτ) i glikoproteina graviditeta (PAG’s). Lutealna dinamika predstavlja
bitan činilac, bilo da je to stvaranje uslova tokom sinhronizacije za ambijent sa niskom
koncentracijom, ili po oplođenju sa visokom koncentracijom progesterona,
rezultirajući boljim reproduktivnim pokazateljima stanja farme. Visoka koncentacija
progesterona u mleku tokom lutealne faze omogućava lako praćenje progesterona
tokom sinhronizacije, kao i u danima nakon oplodnje, omogućavajući menađžmentu
farme izbor odgovarajuće reproduktivne strategije. Detekcija progesterona
metodom fluorescentne polarizacije (FPA) se izdvaja kao praktičan i lako
izvodljiv test koji daje uvid u koncentracije progesterona u mleku u različitim reproduktivnim
fazama krave i otvara mogućnost pravovremenog intervenisanja u
okviru programa za poboljšanje plodnosti na farmi.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022",
title = "Indukcija i sinhronizacija estrusa kod krava i test za ranu dijagnostiku graviditeta",
pages = "37-46",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3183"
}

Šuluburić, A.,& Gvozdić, D.. (2022). Indukcija i sinhronizacija estrusa kod krava i test za ranu dijagnostiku graviditeta. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 37-46.
https://hdl.handle.net/21.15107/rcub_veterinar_3183

Šuluburić A, Gvozdić D. Indukcija i sinhronizacija estrusa kod krava i test za ranu dijagnostiku graviditeta. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022. 2022;:37-46.
https://hdl.handle.net/21.15107/rcub_veterinar_3183 .

Šuluburić, Adam, Gvozdić, Dragan, "Indukcija i sinhronizacija estrusa kod krava i test za ranu dijagnostiku graviditeta" in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022 (2022):37-46,
https://hdl.handle.net/21.15107/rcub_veterinar_3183 .

TY  - CONF
AU  - Fratrić, Natalija
AU  - Vakanjac, Slobodanka
AU  - Stojić, Milica
AU  - Gvozdić, Dragan
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3333
AB  - Primena „precizne tehnologije” u uzgoju mlečnih krava (engl. precision dairy
farming technologies, PDF) predstavlja model upravljanja farmom uz neprekidnu
podršku automatizovanih sistema za praćenje različitih parametara proizvodnje,
reprodukcije, zdravlja i dobrobiti životinja, kao i mogućih uticaja na životnu sredinu. Ovaj model upravljanja farmom je većinom baziran na upotrebi digitalne tehnologije. To podrazumeva korišćenje adekvatnih mernih instrumenata (senzora,
kamera, mikrofona, skala) i analitičkih uređaja (specifičnih softverskih paketa) koji transformišu dobijene podatke u informaciju koja je korisna za uzgajivača. Na
farmama mlečnih krava, PDF omogućava da se u realnom vremenu rukuje velikim brojem podataka iz različitih sistema, na osnovu kojih se mogu donositi važne odluke o upravljanu farmom. Podaci koji se dobijaju aktivnošću senzora mogu
se koristiti za praćenje proizvodnih rezultata (mlečnost, kvalitet mleka), dobrobiti
i adekvatnog smeštaja (spoljašnja temperatura, vlažnost vazduha), kao fiziološkog stanja krava (detekcija estrusa, vreme teljenja), problema sa zdravljem (hromost, mastitis, metritis) i metaboličkih problema koji su u vezi sa ishranom. Automatizovani sistemi za praćenje motoričke aktivnosti su najčešće korišćeni sistemi
za otkrivanje estrusa kod krava. Praćenjem motoričke aktivnosti putem senzora,
mogu se korektno predvideti ovulacija i pravo vreme za veštačko osemenjavanje. Na ovaj način se može otkriti 70-80 % krava koje su u estrusu, a mogu se
dobiti i informacije o trajanju i intenzitetu estrusa koje su korisne pri odlučivanju o
vremenu osemenjavanja. Protokoli kontrole reprodukcije, zasnovani na otkrivanju
estrusa pomoću praćenja motoričke aktivnosti (AAM) mogu biti veoma uspešni i
uporedivi sa intenzivnim programima „vremenski ograničenog“ veštačkog osemenjavanja (engl. timed AI protocol, TAI), koji uključuje tretmane gonadotropnim releasing-hormonom (GnRH) i prostaglandinima (PGF2α). Takođe je moguće praćenje i nadgledanje teljenja „na daljinu”, bez uznemiravanja životinje i dodatnog
stresa. Time se omogućava brži oporavak i brže uvođenje u reprodukciju, što se
odražava na povećanje proizvodnje mleka, smanjenje troškova osemenjavanja i
veći broj teladi.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 12. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 07 - 10. oktobar 2021
T1  - Digitalne tehnologije i reprodukcija krava
SP  - 43
EP  - 54
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3333
ER  - 

@conference{
author = "Fratrić, Natalija and Vakanjac, Slobodanka and Stojić, Milica and Gvozdić, Dragan",
year = "2021",
abstract = "Primena „precizne tehnologije” u uzgoju mlečnih krava (engl. precision dairy
farming technologies, PDF) predstavlja model upravljanja farmom uz neprekidnu
podršku automatizovanih sistema za praćenje različitih parametara proizvodnje,
reprodukcije, zdravlja i dobrobiti životinja, kao i mogućih uticaja na životnu sredinu. Ovaj model upravljanja farmom je većinom baziran na upotrebi digitalne tehnologije. To podrazumeva korišćenje adekvatnih mernih instrumenata (senzora,
kamera, mikrofona, skala) i analitičkih uređaja (specifičnih softverskih paketa) koji transformišu dobijene podatke u informaciju koja je korisna za uzgajivača. Na
farmama mlečnih krava, PDF omogućava da se u realnom vremenu rukuje velikim brojem podataka iz različitih sistema, na osnovu kojih se mogu donositi važne odluke o upravljanu farmom. Podaci koji se dobijaju aktivnošću senzora mogu
se koristiti za praćenje proizvodnih rezultata (mlečnost, kvalitet mleka), dobrobiti
i adekvatnog smeštaja (spoljašnja temperatura, vlažnost vazduha), kao fiziološkog stanja krava (detekcija estrusa, vreme teljenja), problema sa zdravljem (hromost, mastitis, metritis) i metaboličkih problema koji su u vezi sa ishranom. Automatizovani sistemi za praćenje motoričke aktivnosti su najčešće korišćeni sistemi
za otkrivanje estrusa kod krava. Praćenjem motoričke aktivnosti putem senzora,
mogu se korektno predvideti ovulacija i pravo vreme za veštačko osemenjavanje. Na ovaj način se može otkriti 70-80 % krava koje su u estrusu, a mogu se
dobiti i informacije o trajanju i intenzitetu estrusa koje su korisne pri odlučivanju o
vremenu osemenjavanja. Protokoli kontrole reprodukcije, zasnovani na otkrivanju
estrusa pomoću praćenja motoričke aktivnosti (AAM) mogu biti veoma uspešni i
uporedivi sa intenzivnim programima „vremenski ograničenog“ veštačkog osemenjavanja (engl. timed AI protocol, TAI), koji uključuje tretmane gonadotropnim releasing-hormonom (GnRH) i prostaglandinima (PGF2α). Takođe je moguće praćenje i nadgledanje teljenja „na daljinu”, bez uznemiravanja životinje i dodatnog
stresa. Time se omogućava brži oporavak i brže uvođenje u reprodukciju, što se
odražava na povećanje proizvodnje mleka, smanjenje troškova osemenjavanja i
veći broj teladi.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "12. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 07 - 10. oktobar 2021",
title = "Digitalne tehnologije i reprodukcija krava",
pages = "43-54",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3333"
}

Fratrić, N., Vakanjac, S., Stojić, M.,& Gvozdić, D.. (2021). Digitalne tehnologije i reprodukcija krava. in 12. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 07 - 10. oktobar 2021
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 43-54.
https://hdl.handle.net/21.15107/rcub_veterinar_3333

Fratrić N, Vakanjac S, Stojić M, Gvozdić D. Digitalne tehnologije i reprodukcija krava. in 12. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 07 - 10. oktobar 2021. 2021;:43-54.
https://hdl.handle.net/21.15107/rcub_veterinar_3333 .

Fratrić, Natalija, Vakanjac, Slobodanka, Stojić, Milica, Gvozdić, Dragan, "Digitalne tehnologije i reprodukcija krava" in 12. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 07 - 10. oktobar 2021 (2021):43-54,
https://hdl.handle.net/21.15107/rcub_veterinar_3333 .

TY  - JOUR
AU  - Duka, Miloš
AU  - Lazić, Zoran
AU  - Bubalo, Marija
AU  - Mihailović, Branko
AU  - Miladinović, Milan
AU  - Gvozdić, Dragan
PY  - 2020
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1908
AB  - Introduction. In order to provide the most favorable conditions for bone healing following implant loading, new techniques such as the use of growth factors to directly or indirectly regulate cell and tissue growth are becoming increasingly popular. Simplicity in producing concentrated thrombocytes derived from platelet-rich plasma has led to increasing application of growth factors derived from thrombocytes, such as PDGF, TGF-β, IGF and VEGF, in order to increase the percentage of bone-to-implant contact that provides better implant stability and possibly earlier functional loading. The aim of the study was to determine the effects of platelet-rich plasma and guided tissue regeneration on bone regeneration in the case of bone defects in early dental implant insertion. Materials and Methods. This experimental study was conducted on 10 study dogs that received 40 BCT implants, i.e., 4 implants per dog. The study included early dental implant placement in the sites of the extracted premolars. Artificial bone defects, resembling peri-implantitis defects, were made on the mesial side of each site, and the defects were filled using suitable guided tissue regeneration protocols with platelet-rich plasma derived from each experimental animal an hour before surgery. Histopathologic and histomorphometric evaluations were performed 10 months following the implantation. Results and Conclusion. The applied protocols had different effects on bone healing. According to the results obtained, the use of platelet-rich plasma combined with deproteinized bovine bone and bovine-derived resorptive membrane provided superior bone defect ossification.
AB  - Uvod. Potreba da se stvore što bolji uslovi za koštano zarastanje nakon ugradnje implantata poslednjih par godina uticala je na primenu faktora rasta koji direktno ili indirektno regulišu rast ćelija i tkiva. Jednostavnost dobijanja koncentrovanih trombocita izdvojenih iz plazme bogate trombocitima, dovela je do sve šire primene faktora rasta poreklom iz trombocita poput PDGF, TGF-β, IGF, VEGF i mnogih drugih, sa ciljem postizanja što većeg procenta kontakta površine implantata sa kosti, što obezbeđuje povećanu stabilnost implantata i brže funkcionalno opterećenje. Cilj rada bio je da se ispita uticaj plazme bogate trombocitima i vođene tkivne regeneracije tkiva u koštanim defektima kod rane ugradnje dentalnih impantata na koštanu regeneraciju. Materijal i metode. Eksperimentalna studija sprovedena je na 10 eksperimentalnih pasa kod kojih je ugrađeno 40 BCT implantata i to po četri svakom. Eksperiment se sastojao od rane ugradnje umplantate na mestima izvađenih premolara. Veštački koštani defekti, nalik periimplantatnim defektima, napravljeni su na mezijalnoj strani svake preparacije. Ti defekti su popunjeni prateći odgovarajuće postupke vodjene tkivne regeneracije, uz korišćenje plazme bogate trombocitima, dobijene iz krvi eksperimentalnih životinja sat vremena pre intervencije. Histopatološke i histomorfometrijske analize rađene su 10 meseci nakon ugradnje implantata. Rezultati i zaključak. Primenjeni protokoli različito utiču na ispunjenost koštanih defekata i koštano zarastanje. Na osnovu dobijenih rezultata došli smo do zaključka da je osifikacija koštanih defekata najveća u protokolu prema kome se primenjuje plazma bogata trombocitima u kombinaciji sa bovinom deproteinizovanom kosti i resorptivnom membranom bovinog porekla.
PB  - Fakultet veterinarske medicine, Beograd, Srbija
T2  - Veterinarski Glasnik
T1  - Effects of local administration of platelet-rich plasma and guided tissue regeneration on bone healing in early inserted dental implants - a histomorphometric analysis
T1  - Efekat lokalne primene plazme bogate trombocitima i vođene regeneracije tkiva na zarastanje kosti kod rane ugradnje dentalnih implantata – histomorfometrijska analiza
VL  - 74
IS  - 1
SP  - 34
EP  - 47
DO  - 10.2298/VETGL171225003D
ER  - 

@article{
author = "Duka, Miloš and Lazić, Zoran and Bubalo, Marija and Mihailović, Branko and Miladinović, Milan and Gvozdić, Dragan",
year = "2020",
abstract = "Introduction. In order to provide the most favorable conditions for bone healing following implant loading, new techniques such as the use of growth factors to directly or indirectly regulate cell and tissue growth are becoming increasingly popular. Simplicity in producing concentrated thrombocytes derived from platelet-rich plasma has led to increasing application of growth factors derived from thrombocytes, such as PDGF, TGF-β, IGF and VEGF, in order to increase the percentage of bone-to-implant contact that provides better implant stability and possibly earlier functional loading. The aim of the study was to determine the effects of platelet-rich plasma and guided tissue regeneration on bone regeneration in the case of bone defects in early dental implant insertion. Materials and Methods. This experimental study was conducted on 10 study dogs that received 40 BCT implants, i.e., 4 implants per dog. The study included early dental implant placement in the sites of the extracted premolars. Artificial bone defects, resembling peri-implantitis defects, were made on the mesial side of each site, and the defects were filled using suitable guided tissue regeneration protocols with platelet-rich plasma derived from each experimental animal an hour before surgery. Histopathologic and histomorphometric evaluations were performed 10 months following the implantation. Results and Conclusion. The applied protocols had different effects on bone healing. According to the results obtained, the use of platelet-rich plasma combined with deproteinized bovine bone and bovine-derived resorptive membrane provided superior bone defect ossification., Uvod. Potreba da se stvore što bolji uslovi za koštano zarastanje nakon ugradnje implantata poslednjih par godina uticala je na primenu faktora rasta koji direktno ili indirektno regulišu rast ćelija i tkiva. Jednostavnost dobijanja koncentrovanih trombocita izdvojenih iz plazme bogate trombocitima, dovela je do sve šire primene faktora rasta poreklom iz trombocita poput PDGF, TGF-β, IGF, VEGF i mnogih drugih, sa ciljem postizanja što većeg procenta kontakta površine implantata sa kosti, što obezbeđuje povećanu stabilnost implantata i brže funkcionalno opterećenje. Cilj rada bio je da se ispita uticaj plazme bogate trombocitima i vođene tkivne regeneracije tkiva u koštanim defektima kod rane ugradnje dentalnih impantata na koštanu regeneraciju. Materijal i metode. Eksperimentalna studija sprovedena je na 10 eksperimentalnih pasa kod kojih je ugrađeno 40 BCT implantata i to po četri svakom. Eksperiment se sastojao od rane ugradnje umplantate na mestima izvađenih premolara. Veštački koštani defekti, nalik periimplantatnim defektima, napravljeni su na mezijalnoj strani svake preparacije. Ti defekti su popunjeni prateći odgovarajuće postupke vodjene tkivne regeneracije, uz korišćenje plazme bogate trombocitima, dobijene iz krvi eksperimentalnih životinja sat vremena pre intervencije. Histopatološke i histomorfometrijske analize rađene su 10 meseci nakon ugradnje implantata. Rezultati i zaključak. Primenjeni protokoli različito utiču na ispunjenost koštanih defekata i koštano zarastanje. Na osnovu dobijenih rezultata došli smo do zaključka da je osifikacija koštanih defekata najveća u protokolu prema kome se primenjuje plazma bogata trombocitima u kombinaciji sa bovinom deproteinizovanom kosti i resorptivnom membranom bovinog porekla.",
publisher = "Fakultet veterinarske medicine, Beograd, Srbija",
journal = "Veterinarski Glasnik",
title = "Effects of local administration of platelet-rich plasma and guided tissue regeneration on bone healing in early inserted dental implants - a histomorphometric analysis, Efekat lokalne primene plazme bogate trombocitima i vođene regeneracije tkiva na zarastanje kosti kod rane ugradnje dentalnih implantata – histomorfometrijska analiza",
volume = "74",
number = "1",
pages = "34-47",
doi = "10.2298/VETGL171225003D"
}

Duka, M., Lazić, Z., Bubalo, M., Mihailović, B., Miladinović, M.,& Gvozdić, D.. (2020). Effects of local administration of platelet-rich plasma and guided tissue regeneration on bone healing in early inserted dental implants - a histomorphometric analysis. in Veterinarski Glasnik
Fakultet veterinarske medicine, Beograd, Srbija., 74(1), 34-47.
https://doi.org/10.2298/VETGL171225003D

Duka M, Lazić Z, Bubalo M, Mihailović B, Miladinović M, Gvozdić D. Effects of local administration of platelet-rich plasma and guided tissue regeneration on bone healing in early inserted dental implants - a histomorphometric analysis. in Veterinarski Glasnik. 2020;74(1):34-47.
doi:10.2298/VETGL171225003D .

Duka, Miloš, Lazić, Zoran, Bubalo, Marija, Mihailović, Branko, Miladinović, Milan, Gvozdić, Dragan, "Effects of local administration of platelet-rich plasma and guided tissue regeneration on bone healing in early inserted dental implants - a histomorphometric analysis" in Veterinarski Glasnik, 74, no. 1 (2020):34-47,
https://doi.org/10.2298/VETGL171225003D . .

Stojić, M., Ilić, V., Kovačić, M., Gvozdić, D., Stajković, S., Vejnović, B., Savić, O.,& Fratrić, N.. (2020). Effects of oral supplementation with organically modified clinoptilolite during prepartum period on colostrum quality in primiparous dairy cows. in Journal of Dairy Research
Cambridge University Press., 87(4), 429-435.
https://hdl.handle.net/21.15107/rcub_veterinar_1976

Stojić M, Ilić V, Kovačić M, Gvozdić D, Stajković S, Vejnović B, Savić O, Fratrić N. Effects of oral supplementation with organically modified clinoptilolite during prepartum period on colostrum quality in primiparous dairy cows. in Journal of Dairy Research. 2020;87(4):429-435.
https://hdl.handle.net/21.15107/rcub_veterinar_1976 .

Stojić, Milica, Ilić, Vesna, Kovačić, Marijana, Gvozdić, Dragan, Stajković, Silvana, Vejnović, Branislav, Savić, Olivera, Fratrić, Natalija, "Effects of oral supplementation with organically modified clinoptilolite during prepartum period on colostrum quality in primiparous dairy cows" in Journal of Dairy Research, 87, no. 4 (2020):429-435,
https://hdl.handle.net/21.15107/rcub_veterinar_1976 .

TY  - CONF
AU  - Fratrić, Natalija
AU  - Gvozdić, Dragan
PY  - 2020
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3334
AB  - Imunski sistem igra važnu ulogu u fertilizaciji, uspostavljanju i održavanju
graviditeta. Imunski mehanizmi semenika opremljeni su fizičkom i imunskom zaštitom antigena spermatozoida (autoantigena) od imunskog sistema domaćina
kao i mehanizmima za suzbijanje mikrobijalnih patogena. U pubertetu kada je
već uspostavljena imunska kompetentnost, germinativne – polne ćelije završavaju svoj prvi ciklus dok se diferentciraju u zrele spermatozoide. U ovom periodu
se sintetiše niz novih površinskih molekula koji se zajedno sa spermatozoidima u
razvoju (autoantigenima) “predstavljaju” imunskom sistemu. Prisustvo fizičke krv
– testis barijere čini da su testisi sisara imunološki privilegovano mesto koje štiti
autoantigene polnih ćelija od sistemskog imunskog odgovora. Lokalni imunomodulatori kao što su makrofagi, ćelije prirodne ubice (engl. natural killer, NK), dendritične ćelije, mastociti i T limfociti ne aktiviraju imunsku reakciju odbacivanja i
na taj način omogućavaju spermatozoidima da izbegnu napad imunskog sistema
(lokalna imunosupresivna sredina).
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 11. Naučni Simpozijum, Reprodukcija domaćih životinja, Divčibare, 8 - 11. oktobar 2020
T1  - Imunologija sperme
SP  - 145
EP  - 155
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3334
ER  - 

@conference{
author = "Fratrić, Natalija and Gvozdić, Dragan",
year = "2020",
abstract = "Imunski sistem igra važnu ulogu u fertilizaciji, uspostavljanju i održavanju
graviditeta. Imunski mehanizmi semenika opremljeni su fizičkom i imunskom zaštitom antigena spermatozoida (autoantigena) od imunskog sistema domaćina
kao i mehanizmima za suzbijanje mikrobijalnih patogena. U pubertetu kada je
već uspostavljena imunska kompetentnost, germinativne – polne ćelije završavaju svoj prvi ciklus dok se diferentciraju u zrele spermatozoide. U ovom periodu
se sintetiše niz novih površinskih molekula koji se zajedno sa spermatozoidima u
razvoju (autoantigenima) “predstavljaju” imunskom sistemu. Prisustvo fizičke krv
– testis barijere čini da su testisi sisara imunološki privilegovano mesto koje štiti
autoantigene polnih ćelija od sistemskog imunskog odgovora. Lokalni imunomodulatori kao što su makrofagi, ćelije prirodne ubice (engl. natural killer, NK), dendritične ćelije, mastociti i T limfociti ne aktiviraju imunsku reakciju odbacivanja i
na taj način omogućavaju spermatozoidima da izbegnu napad imunskog sistema
(lokalna imunosupresivna sredina).",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "11. Naučni Simpozijum, Reprodukcija domaćih životinja, Divčibare, 8 - 11. oktobar 2020",
title = "Imunologija sperme",
pages = "145-155",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3334"
}

Fratrić, N.,& Gvozdić, D.. (2020). Imunologija sperme. in 11. Naučni Simpozijum, Reprodukcija domaćih životinja, Divčibare, 8 - 11. oktobar 2020
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 145-155.
https://hdl.handle.net/21.15107/rcub_veterinar_3334

Fratrić N, Gvozdić D. Imunologija sperme. in 11. Naučni Simpozijum, Reprodukcija domaćih životinja, Divčibare, 8 - 11. oktobar 2020. 2020;:145-155.
https://hdl.handle.net/21.15107/rcub_veterinar_3334 .

Fratrić, Natalija, Gvozdić, Dragan, "Imunologija sperme" in 11. Naučni Simpozijum, Reprodukcija domaćih životinja, Divčibare, 8 - 11. oktobar 2020 (2020):145-155,
https://hdl.handle.net/21.15107/rcub_veterinar_3334 .

TY  - CONF
AU  - Fratrić, Natalija
AU  - Stojić, Milica
AU  - Gvozdić, Dragan
PY  - 2020
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3336
AB  - Digitalne tehnologije današnjeg vremena nalaze svoje mesto u
svim sferama ljudskog rada, pa tako i u veterinarskoj medicini. Na
farmama mlečnih krava, one se koriste za praćenje parametara proizvodnje, ali i fizioloških parametara čime se doprinosi očuvanju zdravlja i dobrobiti životinja, kao i bezbednosti hrane. Digitalna tehnologija
najčešće podrazumeva upotrebu odgovarajućih mernih instrumenata
(senzora, kamera, mikrofona, skala i dr.) i analitičkih uređaja (specifičnih programskih paketa koji služe za obradu prikupljenih informacija) koji na različite načine transformišu dobijene podatke u informaciju
korisnu za držaoce životinja. Novim tehnologijama je omogućeno neprekidno praćenje brojnih parametara u realnom vremenu na određenim mernim mestima, prenos signala do centralnih jedinica i njihov
automatski unos u odgovarajuće programe. Tehnologije bazirane na
senzorima (biosenzorima), na farmama mlečnih krava omogućavaju
da se u realnom vremenu rukuje velikim brojem podataka iz različitih
sistema i na osnovu njih se mogu doneti važne odluke o upravljanu
farmom. Senzori mogu biti postavljeni na različitim mestima: u sistemu automatske muže, pojedinim lokacijama u objektima za držanje
životinja i na/u telu samih krava: ušima, vratu, nogama, repu, pod kožom ili u buragu. Podaci koji se generišu aktivnošću senzora, mogu
se koristiti za praćenje proizvodnih rezultata (mlečnost, broj somatskih
ćelija), uslova dobrobiti i adekvatnog smeštaja (spoljašnja temperatura, vlažnost vazduha), kao i fiziološkog stanja krava (detekcija estrusa). Dobrom obradom podataka se može, u određenim slučajevima,
predvideti buduće stanje životinja, što otvara mogućnost preventivnih
postupaka i aktivnosti veterinara. Primena digitalne tehnologije može značajno uticati na rad veterinara tako što će dovesti do brze transformacije sa terapijskog na preventivni pristup zaštiti zdravlja životinja. Sistem zasnovan na digitalnoj tehnologiji može da: 1) “signalizira”
veterinaru da kod određene životinje postoje promene u vrednostima
određenih homeostatskih parametara, 2) “predlaže” konkretne akcije veterinara u određenom vremenskom okviru, 3) “sugeriše” konkretne
uzroke nastanka promena, 4) integriše podatke iz više značajnih izvora i daje izveštaje, čime se dobijaju nove vrste podataka sa potpuno
novim značenjima.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - XLI Seminar za inovacije znanja veterinara, Beograd, 2020
T1  - Primena digitalne tehnologije na farmama mlečnih krava
SP  - 63
EP  - 72
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3336
ER  - 

@conference{
author = "Fratrić, Natalija and Stojić, Milica and Gvozdić, Dragan",
year = "2020",
abstract = "Digitalne tehnologije današnjeg vremena nalaze svoje mesto u
svim sferama ljudskog rada, pa tako i u veterinarskoj medicini. Na
farmama mlečnih krava, one se koriste za praćenje parametara proizvodnje, ali i fizioloških parametara čime se doprinosi očuvanju zdravlja i dobrobiti životinja, kao i bezbednosti hrane. Digitalna tehnologija
najčešće podrazumeva upotrebu odgovarajućih mernih instrumenata
(senzora, kamera, mikrofona, skala i dr.) i analitičkih uređaja (specifičnih programskih paketa koji služe za obradu prikupljenih informacija) koji na različite načine transformišu dobijene podatke u informaciju
korisnu za držaoce životinja. Novim tehnologijama je omogućeno neprekidno praćenje brojnih parametara u realnom vremenu na određenim mernim mestima, prenos signala do centralnih jedinica i njihov
automatski unos u odgovarajuće programe. Tehnologije bazirane na
senzorima (biosenzorima), na farmama mlečnih krava omogućavaju
da se u realnom vremenu rukuje velikim brojem podataka iz različitih
sistema i na osnovu njih se mogu doneti važne odluke o upravljanu
farmom. Senzori mogu biti postavljeni na različitim mestima: u sistemu automatske muže, pojedinim lokacijama u objektima za držanje
životinja i na/u telu samih krava: ušima, vratu, nogama, repu, pod kožom ili u buragu. Podaci koji se generišu aktivnošću senzora, mogu
se koristiti za praćenje proizvodnih rezultata (mlečnost, broj somatskih
ćelija), uslova dobrobiti i adekvatnog smeštaja (spoljašnja temperatura, vlažnost vazduha), kao i fiziološkog stanja krava (detekcija estrusa). Dobrom obradom podataka se može, u određenim slučajevima,
predvideti buduće stanje životinja, što otvara mogućnost preventivnih
postupaka i aktivnosti veterinara. Primena digitalne tehnologije može značajno uticati na rad veterinara tako što će dovesti do brze transformacije sa terapijskog na preventivni pristup zaštiti zdravlja životinja. Sistem zasnovan na digitalnoj tehnologiji može da: 1) “signalizira”
veterinaru da kod određene životinje postoje promene u vrednostima
određenih homeostatskih parametara, 2) “predlaže” konkretne akcije veterinara u određenom vremenskom okviru, 3) “sugeriše” konkretne
uzroke nastanka promena, 4) integriše podatke iz više značajnih izvora i daje izveštaje, čime se dobijaju nove vrste podataka sa potpuno
novim značenjima.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "XLI Seminar za inovacije znanja veterinara, Beograd, 2020",
title = "Primena digitalne tehnologije na farmama mlečnih krava",
pages = "63-72",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3336"
}

Fratrić, N., Stojić, M.,& Gvozdić, D.. (2020). Primena digitalne tehnologije na farmama mlečnih krava. in XLI Seminar za inovacije znanja veterinara, Beograd, 2020
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 63-72.
https://hdl.handle.net/21.15107/rcub_veterinar_3336

Fratrić N, Stojić M, Gvozdić D. Primena digitalne tehnologije na farmama mlečnih krava. in XLI Seminar za inovacije znanja veterinara, Beograd, 2020. 2020;:63-72.
https://hdl.handle.net/21.15107/rcub_veterinar_3336 .

Fratrić, Natalija, Stojić, Milica, Gvozdić, Dragan, "Primena digitalne tehnologije na farmama mlečnih krava" in XLI Seminar za inovacije znanja veterinara, Beograd, 2020 (2020):63-72,
https://hdl.handle.net/21.15107/rcub_veterinar_3336 .

TY  - CONF
AU  - Fratrić, Natalija
AU  - Stojić, Milica
AU  - Gvozdić, Dragan
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3335
AB  - Imunitet mlečne žlezde zavisi od koordinisanog delovanja elemenata nespecifičnog i specifičnog imuniteta, što uključuje, kako anatomske karakteristike žlezde tako i ćelijske i humoralne odbrambene komponente. Primarne uloge imunskog sistema su da prevenira invaziju - naseljavanje mlečne žlezde bakterijama,
eliminiše postojeću infekciju i uspostavi normalnu funkciju tkiva mlečne žlezde.
Više spoljašnjih i unutrašnjih faktora može uticati na slabljenje imunskog odgovora domaćina, koji dodatno zavisi od virulentnosti i otpornosti različitih mikroorganizama, izazivača mastitisa. Stoga je poznavanje imuniteta mlečne žlezde, kako
u fiziološkim tako i u uslovima inflamacije, ključno za razumevanje prirode intramamarnih infekcija. Imunski odgovor mlečne žlezde varira u zavisnosti od perioda
laktacije mlečnih krava i suprimiran je kod stresa, oko perioda zasušenja i partusa
što povećava osetljivost mlečne žlezde na mastitise.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 10. Naučni simpozijum Reprodukcija domaćih životinja i bolesti mlečne žlezde, Divčibare, 10 - 13. oktobar 2019
T1  - Spečifičnosti imunskog odgovora mlečne žlezde i otpornost na mastite kod mlečnih krava
SP  - 181
SP  - 199
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3335
ER  - 

@conference{
author = "Fratrić, Natalija and Stojić, Milica and Gvozdić, Dragan",
year = "2019",
abstract = "Imunitet mlečne žlezde zavisi od koordinisanog delovanja elemenata nespecifičnog i specifičnog imuniteta, što uključuje, kako anatomske karakteristike žlezde tako i ćelijske i humoralne odbrambene komponente. Primarne uloge imunskog sistema su da prevenira invaziju - naseljavanje mlečne žlezde bakterijama,
eliminiše postojeću infekciju i uspostavi normalnu funkciju tkiva mlečne žlezde.
Više spoljašnjih i unutrašnjih faktora može uticati na slabljenje imunskog odgovora domaćina, koji dodatno zavisi od virulentnosti i otpornosti različitih mikroorganizama, izazivača mastitisa. Stoga je poznavanje imuniteta mlečne žlezde, kako
u fiziološkim tako i u uslovima inflamacije, ključno za razumevanje prirode intramamarnih infekcija. Imunski odgovor mlečne žlezde varira u zavisnosti od perioda
laktacije mlečnih krava i suprimiran je kod stresa, oko perioda zasušenja i partusa
što povećava osetljivost mlečne žlezde na mastitise.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "10. Naučni simpozijum Reprodukcija domaćih životinja i bolesti mlečne žlezde, Divčibare, 10 - 13. oktobar 2019",
title = "Spečifičnosti imunskog odgovora mlečne žlezde i otpornost na mastite kod mlečnih krava",
pages = "181-199",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3335"
}

Fratrić, N., Stojić, M.,& Gvozdić, D.. (2019). Spečifičnosti imunskog odgovora mlečne žlezde i otpornost na mastite kod mlečnih krava. in 10. Naučni simpozijum Reprodukcija domaćih životinja i bolesti mlečne žlezde, Divčibare, 10 - 13. oktobar 2019
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 181.
https://hdl.handle.net/21.15107/rcub_veterinar_3335

Fratrić N, Stojić M, Gvozdić D. Spečifičnosti imunskog odgovora mlečne žlezde i otpornost na mastite kod mlečnih krava. in 10. Naučni simpozijum Reprodukcija domaćih životinja i bolesti mlečne žlezde, Divčibare, 10 - 13. oktobar 2019. 2019;:181.
https://hdl.handle.net/21.15107/rcub_veterinar_3335 .

Fratrić, Natalija, Stojić, Milica, Gvozdić, Dragan, "Spečifičnosti imunskog odgovora mlečne žlezde i otpornost na mastite kod mlečnih krava" in 10. Naučni simpozijum Reprodukcija domaćih životinja i bolesti mlečne žlezde, Divčibare, 10 - 13. oktobar 2019 (2019):181,
https://hdl.handle.net/21.15107/rcub_veterinar_3335 .

TY  - JOUR
AU  - Suluburić, Adam
AU  - Milanović, Svetlana
AU  - Vranješ-Đurić, Sanja
AU  - Jovanović, Ivan B.
AU  - Barna, Tomislav
AU  - Stojić, Milica
AU  - Fratrić, Natalija
AU  - Szenci, Otto
AU  - Gvozdić, Dragan
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1486
AB  - Early embryonic development may be negatively affected by insufficient progesterone (P4) production. Therefore, the aim of our study was to increase P4 by gonadotropin-releasing hormone (GnRH) and/or human chorionic gonadotropin (hCG) treatments after inducing oestrus by prostaglandin (PG) treatment. Lactating Simmental dairy cows (n = 110), between 1 to 5 lactations, with an average milk production of 6,500 l/305 days, at 40-80 days postpartum were used and grouped as follows: (1) PG + GnRH treatment at AI (GnRH group), (2) PG + hCG treatment at day 7 after AI (hCG group), (3) PG + GnRH at AI + hCG treatment at day 7 after AI (GnRH/hCG group), and (4) spontaneous oestrus (C: control group). All animals were double inseminated (at the time of oestrus detection and 12 +/- 2 h thereafter). Blood serum and milk samples were collected at the day of observed oestrus (day 0), and 14, 21 and 28 days after AI. Serum P4 was determined using a commercial radioimmunoassay (RIA) test (INEP, Zemun), and milk P4 was determined using enzyme-linked immunoassay (ELISA) test (NIV Novi Sad). Pregnancy status was confirmed by ultrasonography between days 28 and 35 after AI. Differences of serum or milk P4 medians, pregnancy (and calving) rate were determined using Dunns Multiple Comparison Tests and Z test, respectively. Serum P4 medians were significantly higher at days 14, 21 and 28 after AI in the hCG-treated animals, indicating increased luteal activity, with a similar tendency in whole milk P4 values. Treatment with hCG during the early luteal phase significantly contributed to the maintenance of gestation at days 28-35 after AI, and also increased the calving rate in Simmental dairy cows.
PB  - Akademiai Kiado Rt, Budapest
T2  - Acta Veterinaria Hungarica
T1  - Progesterone concentration, pregnancy and calving rate in simmental dairy cows after oestrus synchronisation and HCG treatment during the early luteal phase
VL  - 65
IS  - 3
SP  - 446
EP  - 458
DO  - 10.1556/004.2017.042
ER  - 

@article{
author = "Suluburić, Adam and Milanović, Svetlana and Vranješ-Đurić, Sanja and Jovanović, Ivan B. and Barna, Tomislav and Stojić, Milica and Fratrić, Natalija and Szenci, Otto and Gvozdić, Dragan",
year = "2017",
abstract = "Early embryonic development may be negatively affected by insufficient progesterone (P4) production. Therefore, the aim of our study was to increase P4 by gonadotropin-releasing hormone (GnRH) and/or human chorionic gonadotropin (hCG) treatments after inducing oestrus by prostaglandin (PG) treatment. Lactating Simmental dairy cows (n = 110), between 1 to 5 lactations, with an average milk production of 6,500 l/305 days, at 40-80 days postpartum were used and grouped as follows: (1) PG + GnRH treatment at AI (GnRH group), (2) PG + hCG treatment at day 7 after AI (hCG group), (3) PG + GnRH at AI + hCG treatment at day 7 after AI (GnRH/hCG group), and (4) spontaneous oestrus (C: control group). All animals were double inseminated (at the time of oestrus detection and 12 +/- 2 h thereafter). Blood serum and milk samples were collected at the day of observed oestrus (day 0), and 14, 21 and 28 days after AI. Serum P4 was determined using a commercial radioimmunoassay (RIA) test (INEP, Zemun), and milk P4 was determined using enzyme-linked immunoassay (ELISA) test (NIV Novi Sad). Pregnancy status was confirmed by ultrasonography between days 28 and 35 after AI. Differences of serum or milk P4 medians, pregnancy (and calving) rate were determined using Dunns Multiple Comparison Tests and Z test, respectively. Serum P4 medians were significantly higher at days 14, 21 and 28 after AI in the hCG-treated animals, indicating increased luteal activity, with a similar tendency in whole milk P4 values. Treatment with hCG during the early luteal phase significantly contributed to the maintenance of gestation at days 28-35 after AI, and also increased the calving rate in Simmental dairy cows.",
publisher = "Akademiai Kiado Rt, Budapest",
journal = "Acta Veterinaria Hungarica",
title = "Progesterone concentration, pregnancy and calving rate in simmental dairy cows after oestrus synchronisation and HCG treatment during the early luteal phase",
volume = "65",
number = "3",
pages = "446-458",
doi = "10.1556/004.2017.042"
}

Suluburić, A., Milanović, S., Vranješ-Đurić, S., Jovanović, I. B., Barna, T., Stojić, M., Fratrić, N., Szenci, O.,& Gvozdić, D.. (2017). Progesterone concentration, pregnancy and calving rate in simmental dairy cows after oestrus synchronisation and HCG treatment during the early luteal phase. in Acta Veterinaria Hungarica
Akademiai Kiado Rt, Budapest., 65(3), 446-458.
https://doi.org/10.1556/004.2017.042

Suluburić A, Milanović S, Vranješ-Đurić S, Jovanović IB, Barna T, Stojić M, Fratrić N, Szenci O, Gvozdić D. Progesterone concentration, pregnancy and calving rate in simmental dairy cows after oestrus synchronisation and HCG treatment during the early luteal phase. in Acta Veterinaria Hungarica. 2017;65(3):446-458.
doi:10.1556/004.2017.042 .

Suluburić, Adam, Milanović, Svetlana, Vranješ-Đurić, Sanja, Jovanović, Ivan B., Barna, Tomislav, Stojić, Milica, Fratrić, Natalija, Szenci, Otto, Gvozdić, Dragan, "Progesterone concentration, pregnancy and calving rate in simmental dairy cows after oestrus synchronisation and HCG treatment during the early luteal phase" in Acta Veterinaria Hungarica, 65, no. 3 (2017):446-458,
https://doi.org/10.1556/004.2017.042 . .

TY  - JOUR
AU  - Stojić, Milica
AU  - Fratrić, Natalija
AU  - Kovacić, Marijana
AU  - Ilić, Vesna
AU  - Gvozdić, Dragan
AU  - Savić, Olivera
AU  - Doković, Radojica
AU  - Valčić, Olivera
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1519
AB  - Failure of passive transfer (FPT) of immunoglobulins (IgG) is associated with increased morbidity and mortality of calves. In this study we evaluated the digital Brix refractometer usefulness for the assessment of FPT. A number of 16 colostrum samples from the first milking (2-3h post-partum) of Holstein-Friesian dairy heifers and 29 blood sera of 3-6 days old calves were analyzed with a digital Brix refractometer. Total proteins were determined by the biuret reaction. Colostral IgG were determined by radial immunodiffusion (RID), and colostral whey and blood serum. globulin (composed almost entirely of IgG) were determined by agarose protein gel electrophoresis (APE) and densitometry. Colostral % Brix score was 25.5 +/- 3.4%. Concentrations of colostrum IgG and colostral whey. globulin were 130 +/- 33 g/L and 100 +/- 24 g/L respectively. The concentration of total proteins in colostral whey was 134 +/- 30 g/L. The correlations between Brix values and the concentrations of IgG determined with RID and the concentrations of. globulin determined with APE were positive and highly significant (P<0.001 and P<0.01). The concentration of serum proteins of new-born calves was 57.75 +/- 11.8 g/L, the concentration of. globulin was 14.4 +/- 7.8 g/L, and the Brix score was 8.6 +/- 1.0%. FPT (serum. globulin<10 g/L) was detected in 34.5% (10/29) calves. Brix score correlated with the concentration of blood serum. globulins in all examined calves. The results have confirmed that digital Brix refractometry allows the producers to use this technique in order to estimate colostral and calf serum IgG, thereby monitoring both colostrum quality and success of passive transfer.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Brix refractometry of colostrum from primiparous dairy cows and new-born calf blood serum in the evaluation of failure of passive transfer
VL  - 67
IS  - 4
SP  - 508
EP  - 524
DO  - 10.1515/acve-2017-0041
ER  - 

@article{
author = "Stojić, Milica and Fratrić, Natalija and Kovacić, Marijana and Ilić, Vesna and Gvozdić, Dragan and Savić, Olivera and Doković, Radojica and Valčić, Olivera",
year = "2017",
abstract = "Failure of passive transfer (FPT) of immunoglobulins (IgG) is associated with increased morbidity and mortality of calves. In this study we evaluated the digital Brix refractometer usefulness for the assessment of FPT. A number of 16 colostrum samples from the first milking (2-3h post-partum) of Holstein-Friesian dairy heifers and 29 blood sera of 3-6 days old calves were analyzed with a digital Brix refractometer. Total proteins were determined by the biuret reaction. Colostral IgG were determined by radial immunodiffusion (RID), and colostral whey and blood serum. globulin (composed almost entirely of IgG) were determined by agarose protein gel electrophoresis (APE) and densitometry. Colostral % Brix score was 25.5 +/- 3.4%. Concentrations of colostrum IgG and colostral whey. globulin were 130 +/- 33 g/L and 100 +/- 24 g/L respectively. The concentration of total proteins in colostral whey was 134 +/- 30 g/L. The correlations between Brix values and the concentrations of IgG determined with RID and the concentrations of. globulin determined with APE were positive and highly significant (P<0.001 and P<0.01). The concentration of serum proteins of new-born calves was 57.75 +/- 11.8 g/L, the concentration of. globulin was 14.4 +/- 7.8 g/L, and the Brix score was 8.6 +/- 1.0%. FPT (serum. globulin<10 g/L) was detected in 34.5% (10/29) calves. Brix score correlated with the concentration of blood serum. globulins in all examined calves. The results have confirmed that digital Brix refractometry allows the producers to use this technique in order to estimate colostral and calf serum IgG, thereby monitoring both colostrum quality and success of passive transfer.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Brix refractometry of colostrum from primiparous dairy cows and new-born calf blood serum in the evaluation of failure of passive transfer",
volume = "67",
number = "4",
pages = "508-524",
doi = "10.1515/acve-2017-0041"
}

Stojić, M., Fratrić, N., Kovacić, M., Ilić, V., Gvozdić, D., Savić, O., Doković, R.,& Valčić, O.. (2017). Brix refractometry of colostrum from primiparous dairy cows and new-born calf blood serum in the evaluation of failure of passive transfer. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 67(4), 508-524.
https://doi.org/10.1515/acve-2017-0041

Stojić M, Fratrić N, Kovacić M, Ilić V, Gvozdić D, Savić O, Doković R, Valčić O. Brix refractometry of colostrum from primiparous dairy cows and new-born calf blood serum in the evaluation of failure of passive transfer. in Acta Veterinaria-Beograd. 2017;67(4):508-524.
doi:10.1515/acve-2017-0041 .

Stojić, Milica, Fratrić, Natalija, Kovacić, Marijana, Ilić, Vesna, Gvozdić, Dragan, Savić, Olivera, Doković, Radojica, Valčić, Olivera, "Brix refractometry of colostrum from primiparous dairy cows and new-born calf blood serum in the evaluation of failure of passive transfer" in Acta Veterinaria-Beograd, 67, no. 4 (2017):508-524,
https://doi.org/10.1515/acve-2017-0041 . .

TY  - JOUR
AU  - Bjelica, Jelena
AU  - Jovanović, Ivan B.
AU  - Ilić, Vesna
AU  - Valčić, Olivera
AU  - Kirovski, Danijela
AU  - Gvozdić, Dragan
AU  - Milanović, Svetlana
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1535
AB  - Both selenium, as an effector and regulator of antioxidative enzymes activity, and thyroid hormones are potent immunomodulators. Besides, selenium incorporated into iodothyronine deiodinases is involved in the thyroid function and thus indirectly regulates the immune response. Studies of the mutual infl uence of selenium and thyroid hormones on the immune response are scarce, hence we analyzed the effects of an iodothyronine deiodinases blocker, propylthiouracil (PTU), and selenium defi ciency on the function of peritoneal macrophages, and titer of naturally occurring anti-sheep red blood cells (SRBC) IgM antibodies in juvenile rats. The experiment was carried out on 64 Wistar male rats allotted to 4 groups: controlselenium adequate PTU-group; selenium adequate, PTU+ group; selenium defi cient, PTU-group; and selenium defi cient, PTU+. The selenium adequate and selenium defi cient groups were fed a diet containing 0.334 and 0.031 mg Se/kg, respectively. PTU+ groups received PTU (150 mg/L) in drinking water. After 3 weeks, thyroxine (T-4), triiodothyronine (T-3), and thyroid stimulating hormone (TSH) were determined. The animals having intermediate concentrations of T-3 (1.56-1.69 nmol/L) and T 4 (41-50 nmol/L) were excluded from further analysis. Thus, PTU+ groups included hypothyroid animals (T-3 <= 1.55 nmol/L; T-4 <= 40 nmol/L), while PTU-groups included euthyroid rats (T-3 <= 1.70 nmol/L; T-4 <= 50 nmol/L). Both groups of selenium defi cient rats had, when compared to the control group, a signifi cantly lower activity of glutathione peroxidase GPx1 and GPx3. Neither selenium defi ciency nor PTU infl uenced the adherence of peritoneal macrophages. Selenium defi ciency signifi cantly decreased the peroxide synthesis in macrophages and signifi cantly increased the titer of anti-SRBC IgM. Hypotyroidism alone or in combination with selenium defi ciency had no infl uence on these parameters.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Effects of selenium and thyroid hormone deficiency on peritoneal macrophages adhesion and occurrence of natural IGM antibodies in juvenile rats
VL  - 67
IS  - 3
SP  - 340
EP  - 355
DO  - 10.1515/acve-2017-0028
ER  - 

@article{
author = "Bjelica, Jelena and Jovanović, Ivan B. and Ilić, Vesna and Valčić, Olivera and Kirovski, Danijela and Gvozdić, Dragan and Milanović, Svetlana",
year = "2017",
abstract = "Both selenium, as an effector and regulator of antioxidative enzymes activity, and thyroid hormones are potent immunomodulators. Besides, selenium incorporated into iodothyronine deiodinases is involved in the thyroid function and thus indirectly regulates the immune response. Studies of the mutual infl uence of selenium and thyroid hormones on the immune response are scarce, hence we analyzed the effects of an iodothyronine deiodinases blocker, propylthiouracil (PTU), and selenium defi ciency on the function of peritoneal macrophages, and titer of naturally occurring anti-sheep red blood cells (SRBC) IgM antibodies in juvenile rats. The experiment was carried out on 64 Wistar male rats allotted to 4 groups: controlselenium adequate PTU-group; selenium adequate, PTU+ group; selenium defi cient, PTU-group; and selenium defi cient, PTU+. The selenium adequate and selenium defi cient groups were fed a diet containing 0.334 and 0.031 mg Se/kg, respectively. PTU+ groups received PTU (150 mg/L) in drinking water. After 3 weeks, thyroxine (T-4), triiodothyronine (T-3), and thyroid stimulating hormone (TSH) were determined. The animals having intermediate concentrations of T-3 (1.56-1.69 nmol/L) and T 4 (41-50 nmol/L) were excluded from further analysis. Thus, PTU+ groups included hypothyroid animals (T-3 <= 1.55 nmol/L; T-4 <= 40 nmol/L), while PTU-groups included euthyroid rats (T-3 <= 1.70 nmol/L; T-4 <= 50 nmol/L). Both groups of selenium defi cient rats had, when compared to the control group, a signifi cantly lower activity of glutathione peroxidase GPx1 and GPx3. Neither selenium defi ciency nor PTU infl uenced the adherence of peritoneal macrophages. Selenium defi ciency signifi cantly decreased the peroxide synthesis in macrophages and signifi cantly increased the titer of anti-SRBC IgM. Hypotyroidism alone or in combination with selenium defi ciency had no infl uence on these parameters.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Effects of selenium and thyroid hormone deficiency on peritoneal macrophages adhesion and occurrence of natural IGM antibodies in juvenile rats",
volume = "67",
number = "3",
pages = "340-355",
doi = "10.1515/acve-2017-0028"
}

Bjelica, J., Jovanović, I. B., Ilić, V., Valčić, O., Kirovski, D., Gvozdić, D.,& Milanović, S.. (2017). Effects of selenium and thyroid hormone deficiency on peritoneal macrophages adhesion and occurrence of natural IGM antibodies in juvenile rats. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 67(3), 340-355.
https://doi.org/10.1515/acve-2017-0028

Bjelica J, Jovanović IB, Ilić V, Valčić O, Kirovski D, Gvozdić D, Milanović S. Effects of selenium and thyroid hormone deficiency on peritoneal macrophages adhesion and occurrence of natural IGM antibodies in juvenile rats. in Acta Veterinaria-Beograd. 2017;67(3):340-355.
doi:10.1515/acve-2017-0028 .

Bjelica, Jelena, Jovanović, Ivan B., Ilić, Vesna, Valčić, Olivera, Kirovski, Danijela, Gvozdić, Dragan, Milanović, Svetlana, "Effects of selenium and thyroid hormone deficiency on peritoneal macrophages adhesion and occurrence of natural IGM antibodies in juvenile rats" in Acta Veterinaria-Beograd, 67, no. 3 (2017):340-355,
https://doi.org/10.1515/acve-2017-0028 . .

TY  - JOUR
AU  - Buac, Marijana
AU  - Mojsilović, Slavko
AU  - Mišić, Dušan
AU  - Vuković, Dejan
AU  - Savić, Olivera
AU  - Valčić, Olivera
AU  - Marković, Dragana
AU  - Gvozdić, Dragan
AU  - Ilić, Vesna
AU  - Fratrić, Natalija
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1403
AB  - In this work we studied if circulating immune complexes (CIC) of calves with bronchopneumonia have the capacity to modulate function of peripheral blood leukocytes of healthy cattle. CIC of three month old calves (6 healthy and 6 diseased) were isolated by PEG precipitation. Peripheral blood mononuclear cells (MNCs) and granulocytes from healthy calves and cows were the CIC responder cells in in vitro tests. The most remarkable increase of adhesiveness to polystyrene and ROS synthesis (assessed by NBT test) was detected in cows granulocytes stimulated with CIC of diseased calves. Results of MTT test showed that CIC of both healthy and diseased calves reduced granulocytes viability. The strongest effect of inhibition of cows granulocytes resulted from CIC of diseased calves. CIC only moderately reduced spontaneous viability of calves MNCs. Again, the strongest effect of CIC isolated from diseased calves was observed. In contrast to the low impact of CIC on non-stimulated cells, their inhibitory effect on viability of mitogen stimulated MNCs was very strong. With CFSE assay we showed that both types of CIC stimulated spontaneous, but inhibited mitogen induced proliferation of calves MNCs. Propidium iodide staining reviled that CIC increased apoptosis/necrosis of both non-stimulated and mitogen stimulated MNCs. CIC of both healthy and diseased calves modulated the function of peripheral blood MNCs and granulocytes, but a stronger effect of CIC of diseased calves was shown. The age of the donors (calves or cows) of the responder cells, and the activation state of these cells, were also of influence.
PB  - Elsevier Sci Ltd, Oxford
T2  - Research in Veterinary Science
T1  - Circulating immune complexes of calves with bronchopneumonia modulate the function of peripheral blood leukocytes: In vitro evaluation
VL  - 106
SP  - 135
EP  - 142
DO  - 10.1016/j.rvsc.2016.04.002
ER  - 

@article{
author = "Buac, Marijana and Mojsilović, Slavko and Mišić, Dušan and Vuković, Dejan and Savić, Olivera and Valčić, Olivera and Marković, Dragana and Gvozdić, Dragan and Ilić, Vesna and Fratrić, Natalija",
year = "2016",
abstract = "In this work we studied if circulating immune complexes (CIC) of calves with bronchopneumonia have the capacity to modulate function of peripheral blood leukocytes of healthy cattle. CIC of three month old calves (6 healthy and 6 diseased) were isolated by PEG precipitation. Peripheral blood mononuclear cells (MNCs) and granulocytes from healthy calves and cows were the CIC responder cells in in vitro tests. The most remarkable increase of adhesiveness to polystyrene and ROS synthesis (assessed by NBT test) was detected in cows granulocytes stimulated with CIC of diseased calves. Results of MTT test showed that CIC of both healthy and diseased calves reduced granulocytes viability. The strongest effect of inhibition of cows granulocytes resulted from CIC of diseased calves. CIC only moderately reduced spontaneous viability of calves MNCs. Again, the strongest effect of CIC isolated from diseased calves was observed. In contrast to the low impact of CIC on non-stimulated cells, their inhibitory effect on viability of mitogen stimulated MNCs was very strong. With CFSE assay we showed that both types of CIC stimulated spontaneous, but inhibited mitogen induced proliferation of calves MNCs. Propidium iodide staining reviled that CIC increased apoptosis/necrosis of both non-stimulated and mitogen stimulated MNCs. CIC of both healthy and diseased calves modulated the function of peripheral blood MNCs and granulocytes, but a stronger effect of CIC of diseased calves was shown. The age of the donors (calves or cows) of the responder cells, and the activation state of these cells, were also of influence.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Research in Veterinary Science",
title = "Circulating immune complexes of calves with bronchopneumonia modulate the function of peripheral blood leukocytes: In vitro evaluation",
volume = "106",
pages = "135-142",
doi = "10.1016/j.rvsc.2016.04.002"
}

Buac, M., Mojsilović, S., Mišić, D., Vuković, D., Savić, O., Valčić, O., Marković, D., Gvozdić, D., Ilić, V.,& Fratrić, N.. (2016). Circulating immune complexes of calves with bronchopneumonia modulate the function of peripheral blood leukocytes: In vitro evaluation. in Research in Veterinary Science
Elsevier Sci Ltd, Oxford., 106, 135-142.
https://doi.org/10.1016/j.rvsc.2016.04.002

Buac M, Mojsilović S, Mišić D, Vuković D, Savić O, Valčić O, Marković D, Gvozdić D, Ilić V, Fratrić N. Circulating immune complexes of calves with bronchopneumonia modulate the function of peripheral blood leukocytes: In vitro evaluation. in Research in Veterinary Science. 2016;106:135-142.
doi:10.1016/j.rvsc.2016.04.002 .

Buac, Marijana, Mojsilović, Slavko, Mišić, Dušan, Vuković, Dejan, Savić, Olivera, Valčić, Olivera, Marković, Dragana, Gvozdić, Dragan, Ilić, Vesna, Fratrić, Natalija, "Circulating immune complexes of calves with bronchopneumonia modulate the function of peripheral blood leukocytes: In vitro evaluation" in Research in Veterinary Science, 106 (2016):135-142,
https://doi.org/10.1016/j.rvsc.2016.04.002 . .

TY  - JOUR
AU  - Vuković, Dejan
AU  - Božić, Aleksandar
AU  - Relić, Renata
AU  - Stančić, Blagoje
AU  - Gvozdić, Dragan
AU  - Kucević, Denis
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1413
AB  - An experiment was conducted to investigate the effects of hormonal synchronization of ovulation on progesterone concentrations in milk and blood serum and on reproductive performance. Sixty Holstein-Friesian cows averaging 8000 L over 305 days of lactation were divided into 2 groups of 30 animals. One-factor ANOVA and a t-test of progesterone concentrations in venous serum and milk revealed that the lowest concentrations of progesterone in milk (Ovsynch 5.8 + 1.0 ng/mL; control 4.5 + 0.6 ng/mL) and blood serum (Ovsynch 1.3 +/- 0.9 ng/mL; control 1.4 +/- 0.5 ng/mL) in both groups were found on the day of estrus or artificial insemination (AI) (both P < 0.05). Increases in the concentrations of progesterone in milk (Ovsynch 17.6 +/- 4.3 ng/mL; control 10.5 +/- 1.9 ng/mL) and blood serum (Ovsynch 3.6 +/- 1.1 ng/mL; control 4.0 +/- 1.0 ng/mL) were observed on day 7 after AI (both P < 0.05). Concentrations of progesterone in milk and blood serum in nonpregnant cows were reduced on day 21 after AI. Assessment of reproductive performance revealed that the application of treatment shortened the duration of the service period (Ovsynch 76 days; control 83 days) and the calving interval (Ovsynch 376 days; control 382 days).
PB  - Scientific Technical Research Council Turkey-Tubitak, Ankara
T2  - Turkish Journal of Veterinary & Animal Sciences
T1  - Progesterone concentration in milk and blood serum and reproductive efficiency of cows after Ovsynch treatment
VL  - 40
IS  - 1
SP  - 75
EP  - 80
DO  - 10.3906/vet-1505-17
ER  - 

@article{
author = "Vuković, Dejan and Božić, Aleksandar and Relić, Renata and Stančić, Blagoje and Gvozdić, Dragan and Kucević, Denis",
year = "2016",
abstract = "An experiment was conducted to investigate the effects of hormonal synchronization of ovulation on progesterone concentrations in milk and blood serum and on reproductive performance. Sixty Holstein-Friesian cows averaging 8000 L over 305 days of lactation were divided into 2 groups of 30 animals. One-factor ANOVA and a t-test of progesterone concentrations in venous serum and milk revealed that the lowest concentrations of progesterone in milk (Ovsynch 5.8 + 1.0 ng/mL; control 4.5 + 0.6 ng/mL) and blood serum (Ovsynch 1.3 +/- 0.9 ng/mL; control 1.4 +/- 0.5 ng/mL) in both groups were found on the day of estrus or artificial insemination (AI) (both P < 0.05). Increases in the concentrations of progesterone in milk (Ovsynch 17.6 +/- 4.3 ng/mL; control 10.5 +/- 1.9 ng/mL) and blood serum (Ovsynch 3.6 +/- 1.1 ng/mL; control 4.0 +/- 1.0 ng/mL) were observed on day 7 after AI (both P < 0.05). Concentrations of progesterone in milk and blood serum in nonpregnant cows were reduced on day 21 after AI. Assessment of reproductive performance revealed that the application of treatment shortened the duration of the service period (Ovsynch 76 days; control 83 days) and the calving interval (Ovsynch 376 days; control 382 days).",
publisher = "Scientific Technical Research Council Turkey-Tubitak, Ankara",
journal = "Turkish Journal of Veterinary & Animal Sciences",
title = "Progesterone concentration in milk and blood serum and reproductive efficiency of cows after Ovsynch treatment",
volume = "40",
number = "1",
pages = "75-80",
doi = "10.3906/vet-1505-17"
}

Vuković, D., Božić, A., Relić, R., Stančić, B., Gvozdić, D.,& Kucević, D.. (2016). Progesterone concentration in milk and blood serum and reproductive efficiency of cows after Ovsynch treatment. in Turkish Journal of Veterinary & Animal Sciences
Scientific Technical Research Council Turkey-Tubitak, Ankara., 40(1), 75-80.
https://doi.org/10.3906/vet-1505-17

Vuković D, Božić A, Relić R, Stančić B, Gvozdić D, Kucević D. Progesterone concentration in milk and blood serum and reproductive efficiency of cows after Ovsynch treatment. in Turkish Journal of Veterinary & Animal Sciences. 2016;40(1):75-80.
doi:10.3906/vet-1505-17 .

Vuković, Dejan, Božić, Aleksandar, Relić, Renata, Stančić, Blagoje, Gvozdić, Dragan, Kucević, Denis, "Progesterone concentration in milk and blood serum and reproductive efficiency of cows after Ovsynch treatment" in Turkish Journal of Veterinary & Animal Sciences, 40, no. 1 (2016):75-80,
https://doi.org/10.3906/vet-1505-17 . .

TY  - CONF
AU  - Milanović, Aleksandar
AU  - Barna, Tomislav
AU  - Apić, Jelena
AU  - Kujača, Velibor
AU  - Lazarević, Miodrag
AU  - Gvozdić, Dragan
AU  - Maksimović, N.
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3933
AB  - The aim of this study was to determine the impact of the level of progesterone in
the cycle preceding insemination, as well as the ability to shorten the open days period of
primiparous cows which were under the control of progesterone (P group - 43 cows),
compared to the control group of primiparous cows that was not under progesterone
supervision (C group – 62 cows). Progesterone concentration was determined in the whole
milk by EIA test.
The concentration of progesterone in the diestrus preceding the first insemination was
significantly higher for the cows that become pregnant, in relation to the non-pregnant
cows (6.70±2.77 ng/m to 3.60±1.92 ng/ml; p> 0.01). Values for the concentration of
progesterone ≥5ng/ml in the above period provided a very high probability of conception
(80%).
Time to first insemination in the group P was reduced by 10.56 days (83.03 vs. 93.59
days), and the number of inseminations decreased by 0.24 (1.14 vs. 1.38), but no statistical
significance was observed. Statistical significance was determined for shortening of the
open days period by 25.06 days in the P group (80.46 vs. 105.52 days, p=0.024).
Progesterone test can be used as a reliable tool in the control of sexual cycle, for better
understanding of the physiological significance of different concentrations of progesterone
in the conception as well as in the improvement of reproductive parameters in high
productive animals.
PB  - Novi Sad : Poljoprivredni fakultet
C3  - The International Symposium on Animal Science (ISAS), 19th International Congress on Biotechnology in Animal Reproduction (ICBAR), Novi Sad, 9 - 11. 9. 2015
T1  - The effect of progesterone monitoring in improving reproductive efficiency in first lactating dairy cows
SP  - 31
EP  - 38
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3933
ER  - 

@conference{
author = "Milanović, Aleksandar and Barna, Tomislav and Apić, Jelena and Kujača, Velibor and Lazarević, Miodrag and Gvozdić, Dragan and Maksimović, N.",
year = "2015",
abstract = "The aim of this study was to determine the impact of the level of progesterone in
the cycle preceding insemination, as well as the ability to shorten the open days period of
primiparous cows which were under the control of progesterone (P group - 43 cows),
compared to the control group of primiparous cows that was not under progesterone
supervision (C group – 62 cows). Progesterone concentration was determined in the whole
milk by EIA test.
The concentration of progesterone in the diestrus preceding the first insemination was
significantly higher for the cows that become pregnant, in relation to the non-pregnant
cows (6.70±2.77 ng/m to 3.60±1.92 ng/ml; p> 0.01). Values for the concentration of
progesterone ≥5ng/ml in the above period provided a very high probability of conception
(80%).
Time to first insemination in the group P was reduced by 10.56 days (83.03 vs. 93.59
days), and the number of inseminations decreased by 0.24 (1.14 vs. 1.38), but no statistical
significance was observed. Statistical significance was determined for shortening of the
open days period by 25.06 days in the P group (80.46 vs. 105.52 days, p=0.024).
Progesterone test can be used as a reliable tool in the control of sexual cycle, for better
understanding of the physiological significance of different concentrations of progesterone
in the conception as well as in the improvement of reproductive parameters in high
productive animals.",
publisher = "Novi Sad : Poljoprivredni fakultet",
journal = "The International Symposium on Animal Science (ISAS), 19th International Congress on Biotechnology in Animal Reproduction (ICBAR), Novi Sad, 9 - 11. 9. 2015",
title = "The effect of progesterone monitoring in improving reproductive efficiency in first lactating dairy cows",
pages = "31-38",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3933"
}

Milanović, A., Barna, T., Apić, J., Kujača, V., Lazarević, M., Gvozdić, D.,& Maksimović, N.. (2015). The effect of progesterone monitoring in improving reproductive efficiency in first lactating dairy cows. in The International Symposium on Animal Science (ISAS), 19th International Congress on Biotechnology in Animal Reproduction (ICBAR), Novi Sad, 9 - 11. 9. 2015
Novi Sad : Poljoprivredni fakultet., 31-38.
https://hdl.handle.net/21.15107/rcub_veterinar_3933

Milanović A, Barna T, Apić J, Kujača V, Lazarević M, Gvozdić D, Maksimović N. The effect of progesterone monitoring in improving reproductive efficiency in first lactating dairy cows. in The International Symposium on Animal Science (ISAS), 19th International Congress on Biotechnology in Animal Reproduction (ICBAR), Novi Sad, 9 - 11. 9. 2015. 2015;:31-38.
https://hdl.handle.net/21.15107/rcub_veterinar_3933 .

Milanović, Aleksandar, Barna, Tomislav, Apić, Jelena, Kujača, Velibor, Lazarević, Miodrag, Gvozdić, Dragan, Maksimović, N., "The effect of progesterone monitoring in improving reproductive efficiency in first lactating dairy cows" in The International Symposium on Animal Science (ISAS), 19th International Congress on Biotechnology in Animal Reproduction (ICBAR), Novi Sad, 9 - 11. 9. 2015 (2015):31-38,
https://hdl.handle.net/21.15107/rcub_veterinar_3933 .

TY  - JOUR
AU  - Jovanović, Ivan B.
AU  - Velicković, Miljan
AU  - Milanović, Svetlana
AU  - Valčić, Olivera
AU  - Gvozdić, Dragan
AU  - Vranješ-Đurić, Sanja
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1182
AB  - The aim of this investigation was to determine the influence of oxidative stress upon general stress in dairy cows on parturition and whether the indicators of stress can be reduced by selenium (Se) supplementation. A total of 36 animals were divided into 3 groups 21 days prepartum and treated with a single-term intra muscular supplement of sodium selenite: Control group - 0 mg; group Se10 - 10 mg; group Se20 - 20 mg. Se supplementation significantly raised blood Se content and glutathione peroxidase (GPx) activity in groups Se10 and Se20, compared to Control, although there was no marked difference between supplemented groups. Plasma malondialdehyde (MDA) and cortisol concentrations were significantly reduced in supplemented groups Se10 and Se20, compared to Control. A negative correlation was detected between blood GPx activity and plasma MDA, while a positive correlation was determined between plasma MDA and cortisol concentrations. These results indicate that prepartum Se supplementation can be utilized for a partial relief of stress in cows during labor by augmenting the antioxidative action of GPx.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows
VL  - 65
IS  - 2
SP  - 191
EP  - 201
DO  - 10.1515/acve-2015-0016
ER  - 

@article{
author = "Jovanović, Ivan B. and Velicković, Miljan and Milanović, Svetlana and Valčić, Olivera and Gvozdić, Dragan and Vranješ-Đurić, Sanja",
year = "2015",
abstract = "The aim of this investigation was to determine the influence of oxidative stress upon general stress in dairy cows on parturition and whether the indicators of stress can be reduced by selenium (Se) supplementation. A total of 36 animals were divided into 3 groups 21 days prepartum and treated with a single-term intra muscular supplement of sodium selenite: Control group - 0 mg; group Se10 - 10 mg; group Se20 - 20 mg. Se supplementation significantly raised blood Se content and glutathione peroxidase (GPx) activity in groups Se10 and Se20, compared to Control, although there was no marked difference between supplemented groups. Plasma malondialdehyde (MDA) and cortisol concentrations were significantly reduced in supplemented groups Se10 and Se20, compared to Control. A negative correlation was detected between blood GPx activity and plasma MDA, while a positive correlation was determined between plasma MDA and cortisol concentrations. These results indicate that prepartum Se supplementation can be utilized for a partial relief of stress in cows during labor by augmenting the antioxidative action of GPx.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows",
volume = "65",
number = "2",
pages = "191-201",
doi = "10.1515/acve-2015-0016"
}

Jovanović, I. B., Velicković, M., Milanović, S., Valčić, O., Gvozdić, D.,& Vranješ-Đurić, S.. (2015). Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 65(2), 191-201.
https://doi.org/10.1515/acve-2015-0016

Jovanović IB, Velicković M, Milanović S, Valčić O, Gvozdić D, Vranješ-Đurić S. Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows. in Acta Veterinaria-Beograd. 2015;65(2):191-201.
doi:10.1515/acve-2015-0016 .

Jovanović, Ivan B., Velicković, Miljan, Milanović, Svetlana, Valčić, Olivera, Gvozdić, Dragan, Vranješ-Đurić, Sanja, "Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows" in Acta Veterinaria-Beograd, 65, no. 2 (2015):191-201,
https://doi.org/10.1515/acve-2015-0016 . .

TY  - JOUR
AU  - Šamanc, Horea
AU  - Gvozdić, Dragan
AU  - Fratrić, Natalija
AU  - Kirovski, Danijela
AU  - Đoković, Radojica
AU  - Sadojević, Zeljko
AU  - Cincović, Marko
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1176
AB  - The aim of this study was to investigate the relationship between the loss in body condition score (BCS) and loss (ΔBCS), energy balance (EB), hepatic lipidosis and blood serum concentration of non esterified fatty acids (NEFA), glucose, triacylglycerol (TAG) and total bilirubin (tBIL) in healthy dairy cows during transition period. Twenty healthy Holstein cows were included and categorized into groups based on BCS loss (ΔBCS) between dry period and early lactation (ΔBCS  lt 0.75 and ≥0.75). Significant differences between groups (p lt 0.05) were observed for blood serum NEFA, glucose and tBIL. Cows with high ΔBCS (≥0.75) between dry period and early lactation showed increased blood serum NEFA, TAG and tBIL concentrations and lower blood serum glucose concentration during transition period, compared to the low ΔBCS cows ( lt 0.75). Metabolic profiles of cows during transition period indicate high level of lipid mobilization from adipose tissue, possible decreased liver cells TAG export and gluconeogenic ability and impaired bilirubin metabolism if ΔBCS is increased by more than 0.75 points. ΔBCS was in relation with energy balance (EB) in transition period.
PB  - Polska Akad Nauk, Inst Genetyki I Hodowli Zwierzat, Mrokow
T2  - Animal Science Papers and Reports
T1  - Body condition score loss, hepatic lipidosis and selected blood metabolites in holstein cows during transition period
VL  - 33
IS  - 1
SP  - 35
EP  - 47
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_1176
ER  - 

@article{
author = "Šamanc, Horea and Gvozdić, Dragan and Fratrić, Natalija and Kirovski, Danijela and Đoković, Radojica and Sadojević, Zeljko and Cincović, Marko",
year = "2015",
abstract = "The aim of this study was to investigate the relationship between the loss in body condition score (BCS) and loss (ΔBCS), energy balance (EB), hepatic lipidosis and blood serum concentration of non esterified fatty acids (NEFA), glucose, triacylglycerol (TAG) and total bilirubin (tBIL) in healthy dairy cows during transition period. Twenty healthy Holstein cows were included and categorized into groups based on BCS loss (ΔBCS) between dry period and early lactation (ΔBCS  lt 0.75 and ≥0.75). Significant differences between groups (p lt 0.05) were observed for blood serum NEFA, glucose and tBIL. Cows with high ΔBCS (≥0.75) between dry period and early lactation showed increased blood serum NEFA, TAG and tBIL concentrations and lower blood serum glucose concentration during transition period, compared to the low ΔBCS cows ( lt 0.75). Metabolic profiles of cows during transition period indicate high level of lipid mobilization from adipose tissue, possible decreased liver cells TAG export and gluconeogenic ability and impaired bilirubin metabolism if ΔBCS is increased by more than 0.75 points. ΔBCS was in relation with energy balance (EB) in transition period.",
publisher = "Polska Akad Nauk, Inst Genetyki I Hodowli Zwierzat, Mrokow",
journal = "Animal Science Papers and Reports",
title = "Body condition score loss, hepatic lipidosis and selected blood metabolites in holstein cows during transition period",
volume = "33",
number = "1",
pages = "35-47",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_1176"
}

Šamanc, H., Gvozdić, D., Fratrić, N., Kirovski, D., Đoković, R., Sadojević, Z.,& Cincović, M.. (2015). Body condition score loss, hepatic lipidosis and selected blood metabolites in holstein cows during transition period. in Animal Science Papers and Reports
Polska Akad Nauk, Inst Genetyki I Hodowli Zwierzat, Mrokow., 33(1), 35-47.
https://hdl.handle.net/21.15107/rcub_veterinar_1176

Šamanc H, Gvozdić D, Fratrić N, Kirovski D, Đoković R, Sadojević Z, Cincović M. Body condition score loss, hepatic lipidosis and selected blood metabolites in holstein cows during transition period. in Animal Science Papers and Reports. 2015;33(1):35-47.
https://hdl.handle.net/21.15107/rcub_veterinar_1176 .

Šamanc, Horea, Gvozdić, Dragan, Fratrić, Natalija, Kirovski, Danijela, Đoković, Radojica, Sadojević, Zeljko, Cincović, Marko, "Body condition score loss, hepatic lipidosis and selected blood metabolites in holstein cows during transition period" in Animal Science Papers and Reports, 33, no. 1 (2015):35-47,
https://hdl.handle.net/21.15107/rcub_veterinar_1176 .

TY  - JOUR
AU  - Vuković, D.
AU  - Stančić, Ivan
AU  - Gvozdić, Dragan
AU  - Kucević, D.
AU  - Božić, Aleksandar
AU  - Jovanović, Ivan B.
AU  - Milanović, Svetlana
AU  - Stančić, Blagoje
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1107
AB  - Fertiliy rate in high milk-yield dairy cows, with prolonged postpartum anestrus, was investigated after treatment by Ovsynch protocol. Thirty cows with follicular cysts or unovulated follicles (around 1.2 cm in diameter), without detected estrus up to 60 days post partum, were treated by Ovsynch protocol. The date of the first GnRH injection was defined as day 0. On day 6. was given prostaglandin F2α (PGF2a) and second GnRH injection 48 h after PGF2 α (day 8). All treated cows were terminally inseminated at day 9 (without estrus detection), i.e. 12-14 h after the last GnRH injection. The blood serum progesterone concentration was determined by ELISA method, in blood samples taken from v. jugularis, at the day of AI.The blood serum concentration of progesterone on the day of AI was low in Ovsynch treated (1.8 ng/mL) and in control cows (1.5 ng/mL). Obtainedcalving rate was not significant different between treated and control cows (57:60%, respectively, p > 0.05). Our results show that Ovsynch protocol treatment can be a successful method for control of prolonged postpartum anestrus in high milk-yield cows.
PB  - Eugen Ulmer Gmbh Co, Stuttgart
T2  - Zuchtungskunde
T1  - Influence of ovsynch-treatment on concentration of progesterone in blood serum and pregnancy rates after artificial insemination in cows [Einfluss einer Ovsynch-Behandlung auf die Progesteronkonzentrationen im Blutserum und Trächtigkeitsraten bei Kühen na
VL  - 86
IS  - 2
SP  - 123
EP  - 129
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_1107
ER  - 

@article{
author = "Vuković, D. and Stančić, Ivan and Gvozdić, Dragan and Kucević, D. and Božić, Aleksandar and Jovanović, Ivan B. and Milanović, Svetlana and Stančić, Blagoje",
year = "2014",
abstract = "Fertiliy rate in high milk-yield dairy cows, with prolonged postpartum anestrus, was investigated after treatment by Ovsynch protocol. Thirty cows with follicular cysts or unovulated follicles (around 1.2 cm in diameter), without detected estrus up to 60 days post partum, were treated by Ovsynch protocol. The date of the first GnRH injection was defined as day 0. On day 6. was given prostaglandin F2α (PGF2a) and second GnRH injection 48 h after PGF2 α (day 8). All treated cows were terminally inseminated at day 9 (without estrus detection), i.e. 12-14 h after the last GnRH injection. The blood serum progesterone concentration was determined by ELISA method, in blood samples taken from v. jugularis, at the day of AI.The blood serum concentration of progesterone on the day of AI was low in Ovsynch treated (1.8 ng/mL) and in control cows (1.5 ng/mL). Obtainedcalving rate was not significant different between treated and control cows (57:60%, respectively, p > 0.05). Our results show that Ovsynch protocol treatment can be a successful method for control of prolonged postpartum anestrus in high milk-yield cows.",
publisher = "Eugen Ulmer Gmbh Co, Stuttgart",
journal = "Zuchtungskunde",
title = "Influence of ovsynch-treatment on concentration of progesterone in blood serum and pregnancy rates after artificial insemination in cows [Einfluss einer Ovsynch-Behandlung auf die Progesteronkonzentrationen im Blutserum und Trächtigkeitsraten bei Kühen na",
volume = "86",
number = "2",
pages = "123-129",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_1107"
}

Vuković, D., Stančić, I., Gvozdić, D., Kucević, D., Božić, A., Jovanović, I. B., Milanović, S.,& Stančić, B.. (2014). Influence of ovsynch-treatment on concentration of progesterone in blood serum and pregnancy rates after artificial insemination in cows [Einfluss einer Ovsynch-Behandlung auf die Progesteronkonzentrationen im Blutserum und Trächtigkeitsraten bei Kühen na. in Zuchtungskunde
Eugen Ulmer Gmbh Co, Stuttgart., 86(2), 123-129.
https://hdl.handle.net/21.15107/rcub_veterinar_1107

Vuković D, Stančić I, Gvozdić D, Kucević D, Božić A, Jovanović IB, Milanović S, Stančić B. Influence of ovsynch-treatment on concentration of progesterone in blood serum and pregnancy rates after artificial insemination in cows [Einfluss einer Ovsynch-Behandlung auf die Progesteronkonzentrationen im Blutserum und Trächtigkeitsraten bei Kühen na. in Zuchtungskunde. 2014;86(2):123-129.
https://hdl.handle.net/21.15107/rcub_veterinar_1107 .

Vuković, D., Stančić, Ivan, Gvozdić, Dragan, Kucević, D., Božić, Aleksandar, Jovanović, Ivan B., Milanović, Svetlana, Stančić, Blagoje, "Influence of ovsynch-treatment on concentration of progesterone in blood serum and pregnancy rates after artificial insemination in cows [Einfluss einer Ovsynch-Behandlung auf die Progesteronkonzentrationen im Blutserum und Trächtigkeitsraten bei Kühen na" in Zuchtungskunde, 86, no. 2 (2014):123-129,
https://hdl.handle.net/21.15107/rcub_veterinar_1107 .

TY  - JOUR
AU  - Milanović, Svetlana
AU  - Jovanović, Ivan B.
AU  - Bjelica, Jelena
AU  - Joksimović, Srđan
AU  - Stefanović, Srđan
AU  - Radović, Magdalena
AU  - Kirovski, Danijela
AU  - Valčić, Olivera
AU  - Gvozdić, Dragan
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1121
AB  - In this work there was investigated the influence of selenium and deodinases blockers on juvenile rats body weight during three months. The experiment was carried out on 64 rats divided into eight groups with eight individual animals per group. Following groups were formed: 1. Se+PTU-IA- (control group), 2. Se+PTU+IA+, 3. Se+PTU+IA-, 4. Se+P-TU-IA+, 5. Se-PTU-IA-, 6. Se-PTU+IA+, 7. Se-PTU+IA- and 8. Se-PTU-IA+. The groups labeled (Se+) were selenium adequate and they were fed with food that contained 0.334 mg Se/kg. The groups labeled (Se-) were selenium deficient and obtained food with 0.031 mg Se/kg. As deiodinases blockers there were used propylthiouracil (PTU+) in a dose of 150 mg/L of drinking water and iopanoic acid (IA+) in a dose of 6 mg/100 g TM intraperitoneally. Body weight of experimental rats was measured every seven days. After three weeks of treatment there were taken blood samples of animals from all experimental groups and following parameters were determined: selenium concentration in blood, thyroxine (T4), triiodothyronine (T3) and thyroidstimulating hormone (TSH) in blood plasma. Analysis of the samples showed that the animals from the groups treated with PTU had lower body weight in regard to the control group, as well as lower concentration of T3 and T4 in plasma. Selenium deficient rats had lower average body weight compared to the selenium adequate ones after three weeks, but there were no differences in thyroid hormones concentration. The lowest average body weight was noticed in selenium deficient rats groups treated with PTU.
AB  - U okviru ogleda je ispitivan uticaj selena i blokatora dejodinaza na telesnu masu juvenilnih pacova tokom tri nedelje. Ogled je izveden na 64 pacova podeljenih u osam grupa od po 8 jedinki. Formirane su sledeće grupe: 1. Se+PTU-IA- (kontrolna grupa), 2. Se+PTU+IA+, 3. Se+PTU+IA-, 4. Se+PTU-IA+, 5. Se-PTU-IA-, 6. Se-PTU+IA+, 7. Se-PTU+IA- i 8. Se-PTU-IA+. Grupe sa oznakom (Se+) su bile selenadekvatne i dobijale su hranu koja je sadržala 0,334 mg Se/kg hrane. Grupe sa oznakom (Se-) su bile selendeficitne i dobijale su 0,031 mg mg Se/kg hrane. Kao blokatori dejodinaza su korišćeni propiltiouracil (PTU+) u dozi od 150 mg/L vode za piće i jopanoična kiselina (IA+) u dozi od 6 mg/100g t.m. intraperitonealno. Telesna masa oglednih pacova je merena svakih sedam dana. Nakon tri nedelje tretmana uzeti su uzorci krvi životinja iz svih oglednih grupa i određivani su sledeći parametri: koncentracja selena u punoj krvi, tiroksin (T4), trijodtironin (T3) i tireostimulirajući hormon (TSH) u krvnoj plazmi. Analiza je pokazala da su jedinke iz grupe tretiranih sa PTU imale nižu telesnu masu u odnosu na kontrolnu, kao i nižu koncentraciju T3 i T4 u plazmi. Selendeficitni pacovi su nakon tri nedelje imali nižu prosečnu telesnu masu u odnosu na selenadekvatne, ali nisu uočene razlike u koncentraciji tireoidnih hormona. Najniža prosečna telesna masa zabeležena je kod selendeficitnih grupa pacova tretiranih sa PTU.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - The influence of selenium and deiodinases blockers on juvenile rats body weight
T1  - Vlijanie selena i blokatorov dejodinazy na ves juvenil'nyh krys
T1  - Uticaj selena i blokatora dejodinaza na telesnu masu juvenilnih pacova
VL  - 68
IS  - 1-2
SP  - 3
EP  - 9
DO  - 10.2298/VETGL1402003M
ER  - 

@article{
author = "Milanović, Svetlana and Jovanović, Ivan B. and Bjelica, Jelena and Joksimović, Srđan and Stefanović, Srđan and Radović, Magdalena and Kirovski, Danijela and Valčić, Olivera and Gvozdić, Dragan",
year = "2014",
abstract = "In this work there was investigated the influence of selenium and deodinases blockers on juvenile rats body weight during three months. The experiment was carried out on 64 rats divided into eight groups with eight individual animals per group. Following groups were formed: 1. Se+PTU-IA- (control group), 2. Se+PTU+IA+, 3. Se+PTU+IA-, 4. Se+P-TU-IA+, 5. Se-PTU-IA-, 6. Se-PTU+IA+, 7. Se-PTU+IA- and 8. Se-PTU-IA+. The groups labeled (Se+) were selenium adequate and they were fed with food that contained 0.334 mg Se/kg. The groups labeled (Se-) were selenium deficient and obtained food with 0.031 mg Se/kg. As deiodinases blockers there were used propylthiouracil (PTU+) in a dose of 150 mg/L of drinking water and iopanoic acid (IA+) in a dose of 6 mg/100 g TM intraperitoneally. Body weight of experimental rats was measured every seven days. After three weeks of treatment there were taken blood samples of animals from all experimental groups and following parameters were determined: selenium concentration in blood, thyroxine (T4), triiodothyronine (T3) and thyroidstimulating hormone (TSH) in blood plasma. Analysis of the samples showed that the animals from the groups treated with PTU had lower body weight in regard to the control group, as well as lower concentration of T3 and T4 in plasma. Selenium deficient rats had lower average body weight compared to the selenium adequate ones after three weeks, but there were no differences in thyroid hormones concentration. The lowest average body weight was noticed in selenium deficient rats groups treated with PTU., U okviru ogleda je ispitivan uticaj selena i blokatora dejodinaza na telesnu masu juvenilnih pacova tokom tri nedelje. Ogled je izveden na 64 pacova podeljenih u osam grupa od po 8 jedinki. Formirane su sledeće grupe: 1. Se+PTU-IA- (kontrolna grupa), 2. Se+PTU+IA+, 3. Se+PTU+IA-, 4. Se+PTU-IA+, 5. Se-PTU-IA-, 6. Se-PTU+IA+, 7. Se-PTU+IA- i 8. Se-PTU-IA+. Grupe sa oznakom (Se+) su bile selenadekvatne i dobijale su hranu koja je sadržala 0,334 mg Se/kg hrane. Grupe sa oznakom (Se-) su bile selendeficitne i dobijale su 0,031 mg mg Se/kg hrane. Kao blokatori dejodinaza su korišćeni propiltiouracil (PTU+) u dozi od 150 mg/L vode za piće i jopanoična kiselina (IA+) u dozi od 6 mg/100g t.m. intraperitonealno. Telesna masa oglednih pacova je merena svakih sedam dana. Nakon tri nedelje tretmana uzeti su uzorci krvi životinja iz svih oglednih grupa i određivani su sledeći parametri: koncentracja selena u punoj krvi, tiroksin (T4), trijodtironin (T3) i tireostimulirajući hormon (TSH) u krvnoj plazmi. Analiza je pokazala da su jedinke iz grupe tretiranih sa PTU imale nižu telesnu masu u odnosu na kontrolnu, kao i nižu koncentraciju T3 i T4 u plazmi. Selendeficitni pacovi su nakon tri nedelje imali nižu prosečnu telesnu masu u odnosu na selenadekvatne, ali nisu uočene razlike u koncentraciji tireoidnih hormona. Najniža prosečna telesna masa zabeležena je kod selendeficitnih grupa pacova tretiranih sa PTU.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "The influence of selenium and deiodinases blockers on juvenile rats body weight, Vlijanie selena i blokatorov dejodinazy na ves juvenil'nyh krys, Uticaj selena i blokatora dejodinaza na telesnu masu juvenilnih pacova",
volume = "68",
number = "1-2",
pages = "3-9",
doi = "10.2298/VETGL1402003M"
}

Milanović, S., Jovanović, I. B., Bjelica, J., Joksimović, S., Stefanović, S., Radović, M., Kirovski, D., Valčić, O.,& Gvozdić, D.. (2014). The influence of selenium and deiodinases blockers on juvenile rats body weight. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 68(1-2), 3-9.
https://doi.org/10.2298/VETGL1402003M

Milanović S, Jovanović IB, Bjelica J, Joksimović S, Stefanović S, Radović M, Kirovski D, Valčić O, Gvozdić D. The influence of selenium and deiodinases blockers on juvenile rats body weight. in Veterinarski Glasnik. 2014;68(1-2):3-9.
doi:10.2298/VETGL1402003M .

Milanović, Svetlana, Jovanović, Ivan B., Bjelica, Jelena, Joksimović, Srđan, Stefanović, Srđan, Radović, Magdalena, Kirovski, Danijela, Valčić, Olivera, Gvozdić, Dragan, "The influence of selenium and deiodinases blockers on juvenile rats body weight" in Veterinarski Glasnik, 68, no. 1-2 (2014):3-9,
https://doi.org/10.2298/VETGL1402003M . .