Vasilev, Saša

Link to this page

Authority KeyName Variants
orcid::0000-0001-7870-2713
  • Vasilev, Saša (5)
Projects

Author's Bibliography

Trichinella infection in Serbia from 2011 to 2020: a success story in the field of One Health

Vasilev, Saša; Mitić, Ivana; Mirilović, Milorad; Plavša, Dragana; Milakara, Emina; Plavšić, Budimir; Sofronić-Milosavljević, Ljiljana

(Cambridge University Press, 2023)

TY  - JOUR
AU  - Vasilev, Saša
AU  - Mitić, Ivana
AU  - Mirilović, Milorad
AU  - Plavša, Dragana
AU  - Milakara, Emina
AU  - Plavšić, Budimir
AU  - Sofronić-Milosavljević, Ljiljana
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2541
AB  - In Serbia, modern pork production systems with implemented control measures, including
the detection of Trichinella larvae in meat (ISO18743), have eliminated farmed pork from
pigs slaughtered at abattoirs as a source of trichinellosis. Epidemiological data from 2011 to
2020 indicate that the number of human cases and the number of infected domestic pigs
has decreased significantly. Over the years, pork was the most frequent source of human
infection. Cases generally occurred in small family outbreaks, and the infection was linked
to consumption of raw or undercooked pork from backyard pigs. In most of the outbreaks,
T. spiralis was the aetiological agent of infection, but in 2016, a large outbreak was caused
by consumption of uninspected wild boar meat containing T. britovi larvae. To achieve safe
pork, it is important that consumers of pork from animals raised in backyard smallholdings
and of wild game meat are properly educated about the risks associated with consumption of
untested meat. Laboratories conducting Trichinella testing should have a functional quality
assurance system to ensure competency of analysts and that accurate and repeatable results
are achieved. Regular participation in proficiency testing is needed.
PB  - Cambridge University Press
T2  - Epidemiology and Infection
T1  - Trichinella infection in Serbia from 2011 to 2020: a success story in the field of One Health
VL  - 151
VL  - 8
SP  - 20e
DO  - 10.1017/S0950268823000109
ER  - 
@article{
author = "Vasilev, Saša and Mitić, Ivana and Mirilović, Milorad and Plavša, Dragana and Milakara, Emina and Plavšić, Budimir and Sofronić-Milosavljević, Ljiljana",
year = "2023",
abstract = "In Serbia, modern pork production systems with implemented control measures, including
the detection of Trichinella larvae in meat (ISO18743), have eliminated farmed pork from
pigs slaughtered at abattoirs as a source of trichinellosis. Epidemiological data from 2011 to
2020 indicate that the number of human cases and the number of infected domestic pigs
has decreased significantly. Over the years, pork was the most frequent source of human
infection. Cases generally occurred in small family outbreaks, and the infection was linked
to consumption of raw or undercooked pork from backyard pigs. In most of the outbreaks,
T. spiralis was the aetiological agent of infection, but in 2016, a large outbreak was caused
by consumption of uninspected wild boar meat containing T. britovi larvae. To achieve safe
pork, it is important that consumers of pork from animals raised in backyard smallholdings
and of wild game meat are properly educated about the risks associated with consumption of
untested meat. Laboratories conducting Trichinella testing should have a functional quality
assurance system to ensure competency of analysts and that accurate and repeatable results
are achieved. Regular participation in proficiency testing is needed.",
publisher = "Cambridge University Press",
journal = "Epidemiology and Infection",
title = "Trichinella infection in Serbia from 2011 to 2020: a success story in the field of One Health",
volume = "151, 8",
pages = "20e",
doi = "10.1017/S0950268823000109"
}
Vasilev, S., Mitić, I., Mirilović, M., Plavša, D., Milakara, E., Plavšić, B.,& Sofronić-Milosavljević, L.. (2023). Trichinella infection in Serbia from 2011 to 2020: a success story in the field of One Health. in Epidemiology and Infection
Cambridge University Press., 151, 20e.
https://doi.org/10.1017/S0950268823000109
Vasilev S, Mitić I, Mirilović M, Plavša D, Milakara E, Plavšić B, Sofronić-Milosavljević L. Trichinella infection in Serbia from 2011 to 2020: a success story in the field of One Health. in Epidemiology and Infection. 2023;151:20e.
doi:10.1017/S0950268823000109 .
Vasilev, Saša, Mitić, Ivana, Mirilović, Milorad, Plavša, Dragana, Milakara, Emina, Plavšić, Budimir, Sofronić-Milosavljević, Ljiljana, "Trichinella infection in Serbia from 2011 to 2020: a success story in the field of One Health" in Epidemiology and Infection, 151 (2023):20e,
https://doi.org/10.1017/S0950268823000109 . .
1
5

Trichinella infection in Serbia

Vasilev, Saša; Mirilović, Milorad; Ignjatović, Marija; Milakara, Emina; Mitić, Ivana; Plavšić, Budimir; Plavša, Dragana; Bošković, Tamara; Vasilev, Dragan; Karabasil, Nedjeljko; Sabljić, Ljiljana; Ilić, Nataša; Živojinović, Milena; Sofronić Milosavljević, Ljiljana

(Veterinarska komora Republike Srpske, 2022)

TY  - CONF
AU  - Vasilev, Saša
AU  - Mirilović, Milorad
AU  - Ignjatović, Marija
AU  - Milakara, Emina
AU  - Mitić, Ivana
AU  - Plavšić, Budimir
AU  - Plavša, Dragana
AU  - Bošković, Tamara
AU  - Vasilev, Dragan
AU  - Karabasil, Nedjeljko
AU  - Sabljić, Ljiljana
AU  - Ilić, Nataša
AU  - Živojinović, Milena
AU  - Sofronić Milosavljević, Ljiljana
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2486
AB  - U Srbiji trihineloza je jedna od najznačajnijih zoonoza koje se prenose hranom. Prvi izveštaj o nalazu kod svinja je iz 1918. godine, a prvi slučaj kod ljudi 1923. godine u Zemunu. Detekcija prisustva trihinele je prvobitno vršena trihineloskopijom. Od 1984. uvedena je veštačka digestija. Savremeni sistemi proizvodnje svinjskog mesa, mere kontrole, metoda veštačke digestije eliminisali su meso svinja sa velikih farmi kao izvor trihineloze. Prvi put u Srbiji Nacionalna referentna laboratorija za trihinelozu (NRLT) organizovala je 2017. godine kontrolu kvaliteta rada za detekciju larvi trihinele u mesu metodom magnetne mešalice (MSM). Svi učesnici (veterinarski instituti) uspešno su prošli testiranje. Članovi tima NRLT napravili su (2019. godine) novi cELISA test za otkrivanje infekcije trihinelom kod životinja i ljudi i Svetska komisija za trihinelozu ga je prepoznala kao koristan za međunarodnu upotrebu. Epidemiološki podaci iz poslednjih decenija ukazuju da je broj obolelih ljudi kao i broj zaraženih životinja značajno smanjen. Svinjsko meso je godinama najčešći izvor infekcije ljudi u Srbiji. Slučajevi se javljaju u porodičnim epidemijama i rizik je povezan sa konzumacijom svinjskog mesa u kome se nalaze larve Trichinella, a uzgajaju se bez primene higijenskih pravila i životinje nisu veterinarski testirane (epidemija u Obrenovcu i Parizu, Francuska). U većini slučajeva T. spiralis je bila etiološki agens infekcije, ali smo u 2016. godini imali veliku epidemiju izazvanu konzumacijom mesa divljih svinja koje je sadržalo larve T britovi (Čajetina, 123 osobe). Važno je: 1. Lovce i potrošače mesa svinja i mesa divljači u Srbiji edukovati o riziku u vezi sa konzumiranjem neproverenog mesa. 2. Kontrola sistema kvaliteta kod veterinarskih subjekata koji rade testiranje na prisustvo larvi trihinele u uzorcima mesa, kao i redovno učešće u PT.
AB  - In Serbia Trichinellosis is one of the most important foodborne zoonotic diseases. The first report of swine infection was in 1918 and first human case was in 1923. From 1984 artificial digestion was adopted for use in preventing human trichinellosis. Modern pork production systems, implemented control measures, artificial digestion method have eliminated farm pork as a source for trichinellosis. For the first time in Serbia National Reference Laboratory for trichinellosis (NRLT) organized in 2017 proficiency test (PT) for the detection of Trichinella larvae in meat by Magnetic Stirrer Method (MSM). All participants (veterinary institutes) successfully passed the testing. Members of NRLT team made (in 2019) new cELISA test for detection of Trichinella infection in animals and humans and the ICT recognized the test as useful for international use. Epidemiological data from the last decades indicate that the number of human cases as well as the number of infected animals has decreased significantly. Over the years, pork was the most frequent source of human trichinellosis. Cases generally occurred in family outbreaks and risk is linked to untested backyard pork consumption. Meat and meat products offered to relatives and friends may be source of infection with Trichinella when backyard pigs are raised without any compliance with hygienic rules and animals are not veterinary tested. In most numbers of outbreaks T. spiralis were the etiological agent of infection but in 2016 we had a large outbreak provoked by consumption of wild boar meat containing T britovi larvae. It is important that: 1. Hunters and consumers of backyard pigs and wild game meat should be educated about the risk associated with consumption of untested meat. 2. Control of Trichinella QA system in veterinary subjects (testing for Trichinella presence in meat samples) and regularly participation in PTs are needed to achieve safe food for consumers.
PB  - Veterinarska komora Republike Srpske
C3  - 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina)
T1  - Trichinella infection in Serbia
T1  - Infekcija trihinelom u Srbiji
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2486
ER  - 
@conference{
author = "Vasilev, Saša and Mirilović, Milorad and Ignjatović, Marija and Milakara, Emina and Mitić, Ivana and Plavšić, Budimir and Plavša, Dragana and Bošković, Tamara and Vasilev, Dragan and Karabasil, Nedjeljko and Sabljić, Ljiljana and Ilić, Nataša and Živojinović, Milena and Sofronić Milosavljević, Ljiljana",
year = "2022",
abstract = "U Srbiji trihineloza je jedna od najznačajnijih zoonoza koje se prenose hranom. Prvi izveštaj o nalazu kod svinja je iz 1918. godine, a prvi slučaj kod ljudi 1923. godine u Zemunu. Detekcija prisustva trihinele je prvobitno vršena trihineloskopijom. Od 1984. uvedena je veštačka digestija. Savremeni sistemi proizvodnje svinjskog mesa, mere kontrole, metoda veštačke digestije eliminisali su meso svinja sa velikih farmi kao izvor trihineloze. Prvi put u Srbiji Nacionalna referentna laboratorija za trihinelozu (NRLT) organizovala je 2017. godine kontrolu kvaliteta rada za detekciju larvi trihinele u mesu metodom magnetne mešalice (MSM). Svi učesnici (veterinarski instituti) uspešno su prošli testiranje. Članovi tima NRLT napravili su (2019. godine) novi cELISA test za otkrivanje infekcije trihinelom kod životinja i ljudi i Svetska komisija za trihinelozu ga je prepoznala kao koristan za međunarodnu upotrebu. Epidemiološki podaci iz poslednjih decenija ukazuju da je broj obolelih ljudi kao i broj zaraženih životinja značajno smanjen. Svinjsko meso je godinama najčešći izvor infekcije ljudi u Srbiji. Slučajevi se javljaju u porodičnim epidemijama i rizik je povezan sa konzumacijom svinjskog mesa u kome se nalaze larve Trichinella, a uzgajaju se bez primene higijenskih pravila i životinje nisu veterinarski testirane (epidemija u Obrenovcu i Parizu, Francuska). U većini slučajeva T. spiralis je bila etiološki agens infekcije, ali smo u 2016. godini imali veliku epidemiju izazvanu konzumacijom mesa divljih svinja koje je sadržalo larve T britovi (Čajetina, 123 osobe). Važno je: 1. Lovce i potrošače mesa svinja i mesa divljači u Srbiji edukovati o riziku u vezi sa konzumiranjem neproverenog mesa. 2. Kontrola sistema kvaliteta kod veterinarskih subjekata koji rade testiranje na prisustvo larvi trihinele u uzorcima mesa, kao i redovno učešće u PT., In Serbia Trichinellosis is one of the most important foodborne zoonotic diseases. The first report of swine infection was in 1918 and first human case was in 1923. From 1984 artificial digestion was adopted for use in preventing human trichinellosis. Modern pork production systems, implemented control measures, artificial digestion method have eliminated farm pork as a source for trichinellosis. For the first time in Serbia National Reference Laboratory for trichinellosis (NRLT) organized in 2017 proficiency test (PT) for the detection of Trichinella larvae in meat by Magnetic Stirrer Method (MSM). All participants (veterinary institutes) successfully passed the testing. Members of NRLT team made (in 2019) new cELISA test for detection of Trichinella infection in animals and humans and the ICT recognized the test as useful for international use. Epidemiological data from the last decades indicate that the number of human cases as well as the number of infected animals has decreased significantly. Over the years, pork was the most frequent source of human trichinellosis. Cases generally occurred in family outbreaks and risk is linked to untested backyard pork consumption. Meat and meat products offered to relatives and friends may be source of infection with Trichinella when backyard pigs are raised without any compliance with hygienic rules and animals are not veterinary tested. In most numbers of outbreaks T. spiralis were the etiological agent of infection but in 2016 we had a large outbreak provoked by consumption of wild boar meat containing T britovi larvae. It is important that: 1. Hunters and consumers of backyard pigs and wild game meat should be educated about the risk associated with consumption of untested meat. 2. Control of Trichinella QA system in veterinary subjects (testing for Trichinella presence in meat samples) and regularly participation in PTs are needed to achieve safe food for consumers.",
publisher = "Veterinarska komora Republike Srpske",
journal = "27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina)",
title = "Trichinella infection in Serbia, Infekcija trihinelom u Srbiji",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2486"
}
Vasilev, S., Mirilović, M., Ignjatović, M., Milakara, E., Mitić, I., Plavšić, B., Plavša, D., Bošković, T., Vasilev, D., Karabasil, N., Sabljić, L., Ilić, N., Živojinović, M.,& Sofronić Milosavljević, L.. (2022). Trichinella infection in Serbia. in 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina)
Veterinarska komora Republike Srpske..
https://hdl.handle.net/21.15107/rcub_veterinar_2486
Vasilev S, Mirilović M, Ignjatović M, Milakara E, Mitić I, Plavšić B, Plavša D, Bošković T, Vasilev D, Karabasil N, Sabljić L, Ilić N, Živojinović M, Sofronić Milosavljević L. Trichinella infection in Serbia. in 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina). 2022;.
https://hdl.handle.net/21.15107/rcub_veterinar_2486 .
Vasilev, Saša, Mirilović, Milorad, Ignjatović, Marija, Milakara, Emina, Mitić, Ivana, Plavšić, Budimir, Plavša, Dragana, Bošković, Tamara, Vasilev, Dragan, Karabasil, Nedjeljko, Sabljić, Ljiljana, Ilić, Nataša, Živojinović, Milena, Sofronić Milosavljević, Ljiljana, "Trichinella infection in Serbia" in 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina) (2022),
https://hdl.handle.net/21.15107/rcub_veterinar_2486 .

Trichinella spiralis muscle larvae release extracellular vesicles with immunomodulatory properties

Kosanović, Maja; Cvetković, Jelena; Gruden-Movsesijan, Alisa; Vasilev, Saša; Milanović, Svetlana; Ilić, Natasa; Sofronic-Milosavljević, Ljiljana

(Wiley, Hoboken, 2019)

TY  - JOUR
AU  - Kosanović, Maja
AU  - Cvetković, Jelena
AU  - Gruden-Movsesijan, Alisa
AU  - Vasilev, Saša
AU  - Milanović, Svetlana
AU  - Ilić, Natasa
AU  - Sofronic-Milosavljević, Ljiljana
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1785
AB  - Aims Extracellular vesicles (EVs) represent a newly discovered but universal communication tool between cells or organisms. However, few data exist on nematode EVs and none for Trichinella spiralis. Here, we aimed to investigate whether T spiralis muscle larvae produce EVs, whether they carry immunomodulatory proteins and whether they have a role in immunomodulation as a component of excretory-secretory muscle larvae products (ES L1). Methods and results EVs were enriched from conditioned medium of T spiralis muscle larvae. Transmission electron microscopy images showed T spiralis EVs to be 30-80 nm in size, and Western blot confirmed the presence of two out of three glycoproteins with the immunodominant epitope characteristic for muscle larvae of the genus Trichinella. Using a peripheral blood mononuclear cell (PBMC) stimulation assay, it was shown that these EVs elevated production of IL10 and IL6. Conclusion T spiralis muscle larvae produce EVs. Those EVs carry immunomodulatory proteins and have the capacity independently to induce regulatory responses in the same way as the T spiralis excretory-secretory muscle larvae products from which they were isolated.
PB  - Wiley, Hoboken
T2  - Parasite Immunology
T1  - Trichinella spiralis muscle larvae release extracellular vesicles with immunomodulatory properties
VL  - 41
IS  - 10
SP  - e12665
DO  - 10.1111/pim.12665
ER  - 
@article{
author = "Kosanović, Maja and Cvetković, Jelena and Gruden-Movsesijan, Alisa and Vasilev, Saša and Milanović, Svetlana and Ilić, Natasa and Sofronic-Milosavljević, Ljiljana",
year = "2019",
abstract = "Aims Extracellular vesicles (EVs) represent a newly discovered but universal communication tool between cells or organisms. However, few data exist on nematode EVs and none for Trichinella spiralis. Here, we aimed to investigate whether T spiralis muscle larvae produce EVs, whether they carry immunomodulatory proteins and whether they have a role in immunomodulation as a component of excretory-secretory muscle larvae products (ES L1). Methods and results EVs were enriched from conditioned medium of T spiralis muscle larvae. Transmission electron microscopy images showed T spiralis EVs to be 30-80 nm in size, and Western blot confirmed the presence of two out of three glycoproteins with the immunodominant epitope characteristic for muscle larvae of the genus Trichinella. Using a peripheral blood mononuclear cell (PBMC) stimulation assay, it was shown that these EVs elevated production of IL10 and IL6. Conclusion T spiralis muscle larvae produce EVs. Those EVs carry immunomodulatory proteins and have the capacity independently to induce regulatory responses in the same way as the T spiralis excretory-secretory muscle larvae products from which they were isolated.",
publisher = "Wiley, Hoboken",
journal = "Parasite Immunology",
title = "Trichinella spiralis muscle larvae release extracellular vesicles with immunomodulatory properties",
volume = "41",
number = "10",
pages = "e12665",
doi = "10.1111/pim.12665"
}
Kosanović, M., Cvetković, J., Gruden-Movsesijan, A., Vasilev, S., Milanović, S., Ilić, N.,& Sofronic-Milosavljević, L.. (2019). Trichinella spiralis muscle larvae release extracellular vesicles with immunomodulatory properties. in Parasite Immunology
Wiley, Hoboken., 41(10), e12665.
https://doi.org/10.1111/pim.12665
Kosanović M, Cvetković J, Gruden-Movsesijan A, Vasilev S, Milanović S, Ilić N, Sofronic-Milosavljević L. Trichinella spiralis muscle larvae release extracellular vesicles with immunomodulatory properties. in Parasite Immunology. 2019;41(10):e12665.
doi:10.1111/pim.12665 .
Kosanović, Maja, Cvetković, Jelena, Gruden-Movsesijan, Alisa, Vasilev, Saša, Milanović, Svetlana, Ilić, Natasa, Sofronic-Milosavljević, Ljiljana, "Trichinella spiralis muscle larvae release extracellular vesicles with immunomodulatory properties" in Parasite Immunology, 41, no. 10 (2019):e12665,
https://doi.org/10.1111/pim.12665 . .
1
27
13
24

Kliničke manifestacije i mehanizmi toksičnog delovanja hemijskih supstancija

Ćupić, Vitomir; Antonijević, Biljana; Matović, Vesna; Bulat, Zorica; Vasilev, Saša

(Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“, 2013)

TY  - JOUR
AU  - Ćupić, Vitomir
AU  - Antonijević, Biljana
AU  - Matović, Vesna
AU  - Bulat, Zorica
AU  - Vasilev, Saša
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2101
AB  - Kada određena supstacija uđe u organizam, njeno toksično delovanje se klinički
može manifestovati na razne načine, zavisno od vrste poremećaja prouzrokovanog
na nivou ćelije. Vezivanjem za određene endogene molekule, toksična jedinjenja
mogu prouzrokovati poremećaj genske ekspresije (neoplazija, teratogeneza),
poremećaj tekućih ili trenutnih aktivnosti ćelije (tremor, konvulzije, spazam,
aritmija), poremećaj integriteta ćelije (poremećaj sinteze proteina, poremećaj
funkcije ćelijske membrane, smrt ćelije) i poremećaj odnosa sa drugim ćelijama
(poremećaj u hemostazi – krvarenje).
Najteži poremećaji, koji nastaju usled vezivanja hemijskih supstancija sa
takozvanim „kritičnim proteinima” (DNK, RNK), klinički se mogu manifestovati
kao: mutageneza, karcinogeneza, teratogeneza i imunotoksičnost.
AB  - When chemical compound enter the body, its toxic effect may clinical to
demonstrate in different way, depend from kind of disturbance, what that
substance induced in the cell. Binding for endogenous molecules toxic substances can induced disturbance of gens expression (neoplasia, teratogenesis), disturbance
of curently activities of cell (tremor, convulsions, spasm, aritmia), disturbance of
integrity of cell (disturbance of sinthesis of proteins, disturbance of function of cell
membrane, death of cell) and disturbance of relation with other cells (disorders of
hemostasis – bleeding).
The most serious disturbances which may to begin because of binding chemical
substances for so-called “critical proteins” (DNA, RNA) clinical may to
demonstrate as: mutagenesis, carcinogenesis, teratogenesis and as immunotoxicity.
PB  - Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“
T2  - Veterinarski žurnal Republike Srpske
T1  - Kliničke manifestacije i mehanizmi toksičnog delovanja hemijskih supstancija
T1  - Clinical manifestations and toxic effect mechanisms of chemical substances
VL  - 13
IS  - 2
SP  - 117
EP  - 130
DO  - 10.7251/VJRS1302117C
ER  - 
@article{
author = "Ćupić, Vitomir and Antonijević, Biljana and Matović, Vesna and Bulat, Zorica and Vasilev, Saša",
year = "2013",
abstract = "Kada određena supstacija uđe u organizam, njeno toksično delovanje se klinički
može manifestovati na razne načine, zavisno od vrste poremećaja prouzrokovanog
na nivou ćelije. Vezivanjem za određene endogene molekule, toksična jedinjenja
mogu prouzrokovati poremećaj genske ekspresije (neoplazija, teratogeneza),
poremećaj tekućih ili trenutnih aktivnosti ćelije (tremor, konvulzije, spazam,
aritmija), poremećaj integriteta ćelije (poremećaj sinteze proteina, poremećaj
funkcije ćelijske membrane, smrt ćelije) i poremećaj odnosa sa drugim ćelijama
(poremećaj u hemostazi – krvarenje).
Najteži poremećaji, koji nastaju usled vezivanja hemijskih supstancija sa
takozvanim „kritičnim proteinima” (DNK, RNK), klinički se mogu manifestovati
kao: mutageneza, karcinogeneza, teratogeneza i imunotoksičnost., When chemical compound enter the body, its toxic effect may clinical to
demonstrate in different way, depend from kind of disturbance, what that
substance induced in the cell. Binding for endogenous molecules toxic substances can induced disturbance of gens expression (neoplasia, teratogenesis), disturbance
of curently activities of cell (tremor, convulsions, spasm, aritmia), disturbance of
integrity of cell (disturbance of sinthesis of proteins, disturbance of function of cell
membrane, death of cell) and disturbance of relation with other cells (disorders of
hemostasis – bleeding).
The most serious disturbances which may to begin because of binding chemical
substances for so-called “critical proteins” (DNA, RNA) clinical may to
demonstrate as: mutagenesis, carcinogenesis, teratogenesis and as immunotoxicity.",
publisher = "Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“",
journal = "Veterinarski žurnal Republike Srpske",
title = "Kliničke manifestacije i mehanizmi toksičnog delovanja hemijskih supstancija, Clinical manifestations and toxic effect mechanisms of chemical substances",
volume = "13",
number = "2",
pages = "117-130",
doi = "10.7251/VJRS1302117C"
}
Ćupić, V., Antonijević, B., Matović, V., Bulat, Z.,& Vasilev, S.. (2013). Kliničke manifestacije i mehanizmi toksičnog delovanja hemijskih supstancija. in Veterinarski žurnal Republike Srpske
Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“., 13(2), 117-130.
https://doi.org/10.7251/VJRS1302117C
Ćupić V, Antonijević B, Matović V, Bulat Z, Vasilev S. Kliničke manifestacije i mehanizmi toksičnog delovanja hemijskih supstancija. in Veterinarski žurnal Republike Srpske. 2013;13(2):117-130.
doi:10.7251/VJRS1302117C .
Ćupić, Vitomir, Antonijević, Biljana, Matović, Vesna, Bulat, Zorica, Vasilev, Saša, "Kliničke manifestacije i mehanizmi toksičnog delovanja hemijskih supstancija" in Veterinarski žurnal Republike Srpske, 13, no. 2 (2013):117-130,
https://doi.org/10.7251/VJRS1302117C . .

First report of Trichinella britovi in Serbia

Cvetković, Jelena; Teodorović, Vlado; Marucci, Gianluca; Vasilev, Dragan; Vasilev, Saša; Ćirović, Duško; Sofronić-Milosavljević, Ljiljana

(Versita, Warsaw, 2011)

TY  - JOUR
AU  - Cvetković, Jelena
AU  - Teodorović, Vlado
AU  - Marucci, Gianluca
AU  - Vasilev, Dragan
AU  - Vasilev, Saša
AU  - Ćirović, Duško
AU  - Sofronić-Milosavljević, Ljiljana
PY  - 2011
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/801
AB  - In Europe, Serbia ranks among countries with a high prevalence of Trichinella infection in pigs, which continues to be a serious human health problem. While in some Balkan countries, more than one Trichinella species/genotype has been described in both the sylvatic and domestic cycles, these data are lacking for Serbia. To date, only a few Serbian isolates of Trichinella have been genetically specified, and all were classified as T. spiralis. Although transmission of Trichinella from domestic pigs to wildlife could be assumed, neither the infection status nor the species of Trichinella circulating among wildlife in Serbia has been investigated. This study shows the presence of two Trichinella species, T. spiralis and T. britovi, in wild animals originating from five districts in Serbia, where Trichinella infections in domestic pigs and humans have been recorded. Trichinella spiralis was detected in jackals (n = 3), red foxes (n = 2) and a wild cat (n = 1). We also established that wolves (n = 4) and red foxes (n = 2) serve as sylvatic reservoirs for T. britovi. This is the first report on the presence of T. britovi in Serbia.
PB  - Versita, Warsaw
T2  - Acta Parasitologica
T1  - First report of Trichinella britovi in Serbia
VL  - 56
IS  - 2
SP  - 232
EP  - 235
DO  - 10.2478/s11686-011-0022-1
ER  - 
@article{
author = "Cvetković, Jelena and Teodorović, Vlado and Marucci, Gianluca and Vasilev, Dragan and Vasilev, Saša and Ćirović, Duško and Sofronić-Milosavljević, Ljiljana",
year = "2011",
abstract = "In Europe, Serbia ranks among countries with a high prevalence of Trichinella infection in pigs, which continues to be a serious human health problem. While in some Balkan countries, more than one Trichinella species/genotype has been described in both the sylvatic and domestic cycles, these data are lacking for Serbia. To date, only a few Serbian isolates of Trichinella have been genetically specified, and all were classified as T. spiralis. Although transmission of Trichinella from domestic pigs to wildlife could be assumed, neither the infection status nor the species of Trichinella circulating among wildlife in Serbia has been investigated. This study shows the presence of two Trichinella species, T. spiralis and T. britovi, in wild animals originating from five districts in Serbia, where Trichinella infections in domestic pigs and humans have been recorded. Trichinella spiralis was detected in jackals (n = 3), red foxes (n = 2) and a wild cat (n = 1). We also established that wolves (n = 4) and red foxes (n = 2) serve as sylvatic reservoirs for T. britovi. This is the first report on the presence of T. britovi in Serbia.",
publisher = "Versita, Warsaw",
journal = "Acta Parasitologica",
title = "First report of Trichinella britovi in Serbia",
volume = "56",
number = "2",
pages = "232-235",
doi = "10.2478/s11686-011-0022-1"
}
Cvetković, J., Teodorović, V., Marucci, G., Vasilev, D., Vasilev, S., Ćirović, D.,& Sofronić-Milosavljević, L.. (2011). First report of Trichinella britovi in Serbia. in Acta Parasitologica
Versita, Warsaw., 56(2), 232-235.
https://doi.org/10.2478/s11686-011-0022-1
Cvetković J, Teodorović V, Marucci G, Vasilev D, Vasilev S, Ćirović D, Sofronić-Milosavljević L. First report of Trichinella britovi in Serbia. in Acta Parasitologica. 2011;56(2):232-235.
doi:10.2478/s11686-011-0022-1 .
Cvetković, Jelena, Teodorović, Vlado, Marucci, Gianluca, Vasilev, Dragan, Vasilev, Saša, Ćirović, Duško, Sofronić-Milosavljević, Ljiljana, "First report of Trichinella britovi in Serbia" in Acta Parasitologica, 56, no. 2 (2011):232-235,
https://doi.org/10.2478/s11686-011-0022-1 . .
22
13
21