TY  - CONF
AU  - Ćupić, Vitomir
AU  - Ivanović, Saša
AU  - Borozan, Sunčica
AU  - Mujezinović, Indira
AU  - Prevendar Crnić, Andreja
AU  - Bartula, Mirjana
AU  - Velev, Romel
AU  - Ćupić Miladinović, Dejana
AU  - Anadon, Arturo
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2962
AB  - Poznato je da se marihuana (i proizvodi od nje), danas sve više koristi, kako za medicinske, tako i rekreativne svrhe kod ljudi. U skladu sa ovim jeste i činjenica da je poslednjih godina značajno poraslo i naučno interesovanje za primenu marihuane. Najbolji dokaz za to je i broj citata u PubMedu, koji je u
periodu od 2000 do 2002 iznosio svega 40, da bi u periodu od 2014. do 2016. porastao na 458, a danas je još veći. U Severnoj Americi i Evropi su mnoge zemlje donele zakone koji dozvoljavaju medicinsku upotrebu određenih proizvoda proizvedenih od kanabisa kod ljudi, a neke zemlje su donele zakone koji dozvoljavaju i rekreativnu upotrebu. Međutim, sa porastom ove primene, rastao je i broj slučajeva toksikoza kod kućnih ljubimaca, nastalih usled
trovanja marihuanom. Ovaj problem je postao još veći kada su vlasnici životinja u želji da pomognu svojim ljubimcima, kod raznih stanja i poremećaja pokušali iste da izleče, upravo primenom proizvoda od marihuane. Već dugo vremena vlasnici životinja širom sveta postavljaju pitanja: „Da li su marihuana i njeni proizvodi legalni, sigurni i efikasni za lečenje raznih poremećaja kod životinja?“
Imajući ovo u vidu, cilj ovog rada je da se naše kolege (kroz prikaz različitih vrsta marihuane i njenih proizvoda, kao i primera primene istih kod životinja kroz istoriju, te postojeće zakonske regulative i propisa), bar malo upoznaju sa primenom istih (kao lekova i/ili suplemenata) u kliničkoj veterinarskoj praksi, ali i sa mogućim trovanjima i (usled toga) potrebnim upozorenjima vezanim za njihovu primenu.
AB  - It is known that marijuana (and its products) is used more and more today, both for medical and recreational purposes by people. In line with this is the fact that scientific interest in the use of marijuana has grown significantly in recent years. The best evidence for this is the number of citations in PubMed, which in the period from 2000 to 2002 was only 40, and in the period from 2014 to 2016, it increased to 458, and today it is even higher. In North America and Europe, many countries have passed laws allowing the medical use of certain cannabis products in humans, and some countries have passed laws allowing recreational use as well. However, with the increase in this application, the number of cases of toxicosis in pets, caused by marijuana poisoning, also increased. This problem became even greater when animal owners, in their desire to help their pets, tried to cure them of various conditions and disorders, precisely by using marijuana products. For a long time, animal owners around the world have asked the question: "Are marijuana and its products legal, safe and effective for treating various disorders in animals?". Bearing this in mind, the aim of this paper is
that our colleagues (through the presentation of different types of marijuana and its products, as well as examples of their use in animals throughout history, and the existing laws and regulations), become a bit familiar with the application of the same (as medicines and/or supplements) in clinical veterinary practice, but also with possible poisonings and (as a result) necessary warnings related to their use.
PB  - Belgrade : Serbian Society of Toxicology
C3  - 13th International Congress of the Serbian Society of Toxicology and 1st TOXSEE Regional Conference, belgrade, 10 - 12 May, 2023
T1  - Za i protiv primene marihuane (kanabisa) u veterinarskoj medicini
T1  - For and against the use of marijuana (cannabis) in veterinary medicine
SP  - 103
EP  - 105
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2962
ER  - 

@conference{
author = "Ćupić, Vitomir and Ivanović, Saša and Borozan, Sunčica and Mujezinović, Indira and Prevendar Crnić, Andreja and Bartula, Mirjana and Velev, Romel and Ćupić Miladinović, Dejana and Anadon, Arturo",
year = "2023",
abstract = "Poznato je da se marihuana (i proizvodi od nje), danas sve više koristi, kako za medicinske, tako i rekreativne svrhe kod ljudi. U skladu sa ovim jeste i činjenica da je poslednjih godina značajno poraslo i naučno interesovanje za primenu marihuane. Najbolji dokaz za to je i broj citata u PubMedu, koji je u
periodu od 2000 do 2002 iznosio svega 40, da bi u periodu od 2014. do 2016. porastao na 458, a danas je još veći. U Severnoj Americi i Evropi su mnoge zemlje donele zakone koji dozvoljavaju medicinsku upotrebu određenih proizvoda proizvedenih od kanabisa kod ljudi, a neke zemlje su donele zakone koji dozvoljavaju i rekreativnu upotrebu. Međutim, sa porastom ove primene, rastao je i broj slučajeva toksikoza kod kućnih ljubimaca, nastalih usled
trovanja marihuanom. Ovaj problem je postao još veći kada su vlasnici životinja u želji da pomognu svojim ljubimcima, kod raznih stanja i poremećaja pokušali iste da izleče, upravo primenom proizvoda od marihuane. Već dugo vremena vlasnici životinja širom sveta postavljaju pitanja: „Da li su marihuana i njeni proizvodi legalni, sigurni i efikasni za lečenje raznih poremećaja kod životinja?“
Imajući ovo u vidu, cilj ovog rada je da se naše kolege (kroz prikaz različitih vrsta marihuane i njenih proizvoda, kao i primera primene istih kod životinja kroz istoriju, te postojeće zakonske regulative i propisa), bar malo upoznaju sa primenom istih (kao lekova i/ili suplemenata) u kliničkoj veterinarskoj praksi, ali i sa mogućim trovanjima i (usled toga) potrebnim upozorenjima vezanim za njihovu primenu., It is known that marijuana (and its products) is used more and more today, both for medical and recreational purposes by people. In line with this is the fact that scientific interest in the use of marijuana has grown significantly in recent years. The best evidence for this is the number of citations in PubMed, which in the period from 2000 to 2002 was only 40, and in the period from 2014 to 2016, it increased to 458, and today it is even higher. In North America and Europe, many countries have passed laws allowing the medical use of certain cannabis products in humans, and some countries have passed laws allowing recreational use as well. However, with the increase in this application, the number of cases of toxicosis in pets, caused by marijuana poisoning, also increased. This problem became even greater when animal owners, in their desire to help their pets, tried to cure them of various conditions and disorders, precisely by using marijuana products. For a long time, animal owners around the world have asked the question: "Are marijuana and its products legal, safe and effective for treating various disorders in animals?". Bearing this in mind, the aim of this paper is
that our colleagues (through the presentation of different types of marijuana and its products, as well as examples of their use in animals throughout history, and the existing laws and regulations), become a bit familiar with the application of the same (as medicines and/or supplements) in clinical veterinary practice, but also with possible poisonings and (as a result) necessary warnings related to their use.",
publisher = "Belgrade : Serbian Society of Toxicology",
journal = "13th International Congress of the Serbian Society of Toxicology and 1st TOXSEE Regional Conference, belgrade, 10 - 12 May, 2023",
title = "Za i protiv primene marihuane (kanabisa) u veterinarskoj medicini, For and against the use of marijuana (cannabis) in veterinary medicine",
pages = "103-105",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2962"
}

Ćupić, V., Ivanović, S., Borozan, S., Mujezinović, I., Prevendar Crnić, A., Bartula, M., Velev, R., Ćupić Miladinović, D.,& Anadon, A.. (2023). Za i protiv primene marihuane (kanabisa) u veterinarskoj medicini. in 13th International Congress of the Serbian Society of Toxicology and 1st TOXSEE Regional Conference, belgrade, 10 - 12 May, 2023
Belgrade : Serbian Society of Toxicology., 103-105.
https://hdl.handle.net/21.15107/rcub_veterinar_2962

Ćupić V, Ivanović S, Borozan S, Mujezinović I, Prevendar Crnić A, Bartula M, Velev R, Ćupić Miladinović D, Anadon A. Za i protiv primene marihuane (kanabisa) u veterinarskoj medicini. in 13th International Congress of the Serbian Society of Toxicology and 1st TOXSEE Regional Conference, belgrade, 10 - 12 May, 2023. 2023;:103-105.
https://hdl.handle.net/21.15107/rcub_veterinar_2962 .

Ćupić, Vitomir, Ivanović, Saša, Borozan, Sunčica, Mujezinović, Indira, Prevendar Crnić, Andreja, Bartula, Mirjana, Velev, Romel, Ćupić Miladinović, Dejana, Anadon, Arturo, "Za i protiv primene marihuane (kanabisa) u veterinarskoj medicini" in 13th International Congress of the Serbian Society of Toxicology and 1st TOXSEE Regional Conference, belgrade, 10 - 12 May, 2023 (2023):103-105,
https://hdl.handle.net/21.15107/rcub_veterinar_2962 .

TY  - CONF
AU  - Ćupić, Vitomir
AU  - Ivanović, Saša
AU  - Borozan, Sunčica
AU  - Žugić, Gordana
AU  - Mujezinović, Indira
AU  - Prevendar Crnić, Andreja
AU  - Velev, Romel
AU  - Ćupić Miladinović, Dejana
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2686
AB  - Uporedo sa intenziviranjem stočarske proizvodnje i izuzetnim povećanjem produktivnosti kod životinja, neminovno se povećavao i broj primenjenih antimikrobnih lekova. Iako se na svim skupovima ukazuje na sve štete koje neracionalna primena ovih lekova nosi sa sobom, nažalost ona je i dalje prisutna. U veterinarskoj kliničkoj praksi, a naročito u živinarstvu i svinjarstvu, kao ključnim sektorima za proizvodnju namirnica animalnog porekla, upotreba antimikrobnih lekova je u nekim momentima bila narasla do nivoa, koji se mogu smatrati alarmantnm za zdravlje ljudi.
Racionalna primena antimikrobnih lekova u veterinarskoj medicini je od višestrukog značaja. Korišćenjem svakog leka, samoonda kada je on zaista neophodan (indikovan), u pravoj dozi i na
pravi način, ne samo da bi se smanjila potencijalna štetnost takvog leka po samu životinju, već bi i efikasnost njegove primene bila znatno veća. Drugim rečima, smanjio bi se broj rezistentnih
mikroorganizama, a time i terapija bila efikasnija.
Razvoj rezistencije bakterija na antimikrobne lekove, kao što su: tetraciklini, makrolidi i linkozamidi, streptogramini, β-laktamini, aminoglikozidi, sulfonamidi, trimetoprim, fluorohino-
loni, hloramfenikol i florfenikol može nastati usled enzimske inaktivacije, smanjene intracelularne penetracije i akumulacije leka, modifikacije/zaštite/zamene ciljnih mesta delovanja, kao i promene metaboličkih puteva. U ovom procesu učestvuju i imaju značaj u prenošenju rezistencije mobilni genetski elementi, koji nose odgovarajuće gene rezistencije, kao što su plazmidi, transpozoni i integroni, kao i procesi konjugacije, mobilizacije, transdukcije,
i transformacije.
AB  - Along with the intensification of livestock production and the extraordinary increase in productivity in animals, the number of applied antimicrobial drugs inevitably increased. Although all gatherings point out all the harms that irrational use of these drugs brings, unfortunately, it is still present. In veterinary clinical practice, and especially in poultry and pig farming, as key sectors for the production of food of animal origin, the use of antimicrobial drugs has at some point increased to levels that can be considered alarming for human health.
Rational use of antimicrobial drugs in veterinary medicine is of multiple importance. By using each drug, only when it is really necessary (indicated), in the right dose and in the right way, not only would the potential harm of such a drug to the animal itself be reduced, but its effectiveness would be significantly higher. In other words, the number of resistant microorganisms would be reduced, and thus the therapy would be more efficient.
Development of bacterial resistance to antimicrobial drugs, such as: tetracyclines, macrolides and lincosamides, streptogramins, β-lactams, aminoglycosides, sulfonamides, trimethoprim, fluoroquinolones, chloramphenicol and florfenicol may occur due to enzyme inactivation, reduced intracellular penetration and accumulation of the drug, modification/protection/replacement of target sites of action, as well as changes in metabolic pathways. Mobile genetic elements, which
carry the corresponding resistance genes, such as plasmids, transposons and integrons, as well as the processes of conjugation, mobilization, transduction, and transformation, participate in this process and are important in the transmission of resistance.
PB  - Banja Luka : Veterinarska Komora Republike Srpske
C3  - 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15-18. jun 2022
T1  - Primena antimikrobnih lekova u veterinarskoj medicini i mehanizmi rezistencije
SP  - 320
EP  - 323
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2686
ER  - 

@conference{
author = "Ćupić, Vitomir and Ivanović, Saša and Borozan, Sunčica and Žugić, Gordana and Mujezinović, Indira and Prevendar Crnić, Andreja and Velev, Romel and Ćupić Miladinović, Dejana",
year = "2022",
abstract = "Uporedo sa intenziviranjem stočarske proizvodnje i izuzetnim povećanjem produktivnosti kod životinja, neminovno se povećavao i broj primenjenih antimikrobnih lekova. Iako se na svim skupovima ukazuje na sve štete koje neracionalna primena ovih lekova nosi sa sobom, nažalost ona je i dalje prisutna. U veterinarskoj kliničkoj praksi, a naročito u živinarstvu i svinjarstvu, kao ključnim sektorima za proizvodnju namirnica animalnog porekla, upotreba antimikrobnih lekova je u nekim momentima bila narasla do nivoa, koji se mogu smatrati alarmantnm za zdravlje ljudi.
Racionalna primena antimikrobnih lekova u veterinarskoj medicini je od višestrukog značaja. Korišćenjem svakog leka, samoonda kada je on zaista neophodan (indikovan), u pravoj dozi i na
pravi način, ne samo da bi se smanjila potencijalna štetnost takvog leka po samu životinju, već bi i efikasnost njegove primene bila znatno veća. Drugim rečima, smanjio bi se broj rezistentnih
mikroorganizama, a time i terapija bila efikasnija.
Razvoj rezistencije bakterija na antimikrobne lekove, kao što su: tetraciklini, makrolidi i linkozamidi, streptogramini, β-laktamini, aminoglikozidi, sulfonamidi, trimetoprim, fluorohino-
loni, hloramfenikol i florfenikol može nastati usled enzimske inaktivacije, smanjene intracelularne penetracije i akumulacije leka, modifikacije/zaštite/zamene ciljnih mesta delovanja, kao i promene metaboličkih puteva. U ovom procesu učestvuju i imaju značaj u prenošenju rezistencije mobilni genetski elementi, koji nose odgovarajuće gene rezistencije, kao što su plazmidi, transpozoni i integroni, kao i procesi konjugacije, mobilizacije, transdukcije,
i transformacije., Along with the intensification of livestock production and the extraordinary increase in productivity in animals, the number of applied antimicrobial drugs inevitably increased. Although all gatherings point out all the harms that irrational use of these drugs brings, unfortunately, it is still present. In veterinary clinical practice, and especially in poultry and pig farming, as key sectors for the production of food of animal origin, the use of antimicrobial drugs has at some point increased to levels that can be considered alarming for human health.
Rational use of antimicrobial drugs in veterinary medicine is of multiple importance. By using each drug, only when it is really necessary (indicated), in the right dose and in the right way, not only would the potential harm of such a drug to the animal itself be reduced, but its effectiveness would be significantly higher. In other words, the number of resistant microorganisms would be reduced, and thus the therapy would be more efficient.
Development of bacterial resistance to antimicrobial drugs, such as: tetracyclines, macrolides and lincosamides, streptogramins, β-lactams, aminoglycosides, sulfonamides, trimethoprim, fluoroquinolones, chloramphenicol and florfenicol may occur due to enzyme inactivation, reduced intracellular penetration and accumulation of the drug, modification/protection/replacement of target sites of action, as well as changes in metabolic pathways. Mobile genetic elements, which
carry the corresponding resistance genes, such as plasmids, transposons and integrons, as well as the processes of conjugation, mobilization, transduction, and transformation, participate in this process and are important in the transmission of resistance.",
publisher = "Banja Luka : Veterinarska Komora Republike Srpske",
journal = "27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15-18. jun 2022",
title = "Primena antimikrobnih lekova u veterinarskoj medicini i mehanizmi rezistencije",
pages = "320-323",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2686"
}

Ćupić, V., Ivanović, S., Borozan, S., Žugić, G., Mujezinović, I., Prevendar Crnić, A., Velev, R.,& Ćupić Miladinović, D.. (2022). Primena antimikrobnih lekova u veterinarskoj medicini i mehanizmi rezistencije. in 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15-18. jun 2022
Banja Luka : Veterinarska Komora Republike Srpske., 320-323.
https://hdl.handle.net/21.15107/rcub_veterinar_2686

Ćupić V, Ivanović S, Borozan S, Žugić G, Mujezinović I, Prevendar Crnić A, Velev R, Ćupić Miladinović D. Primena antimikrobnih lekova u veterinarskoj medicini i mehanizmi rezistencije. in 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15-18. jun 2022. 2022;:320-323.
https://hdl.handle.net/21.15107/rcub_veterinar_2686 .

Ćupić, Vitomir, Ivanović, Saša, Borozan, Sunčica, Žugić, Gordana, Mujezinović, Indira, Prevendar Crnić, Andreja, Velev, Romel, Ćupić Miladinović, Dejana, "Primena antimikrobnih lekova u veterinarskoj medicini i mehanizmi rezistencije" in 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15-18. jun 2022 (2022):320-323,
https://hdl.handle.net/21.15107/rcub_veterinar_2686 .

TY  - CONF
AU  - Ćupić, Vitomir
AU  - Ivanović, Saša
AU  - Borozan, Sunčica
AU  - Prevendar Crnić, Andreja
AU  - Mujezinović, Indira
AU  - Žugić, Gordana
AU  - Velev, Romel
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2420
AB  - Proizvodnja ribe dramatično je porasla širom sveta i zauzima sve
veći udeo (a time i značaj) u ukupnoj proizvodnji hrane animalnog porekla. Da bi se osigurala ovako velika proizvodnja, treba umanjiti štetni
uticaj brojnih faktora spoljašnje sredine, a pre svega stresova, drastičnih promena u temperaturi, mikroorganizama, kao i raznih hemijskih
supstancija, koje mogu itekako ugroziti život ribe. Od svih nabrojanih
faktora poseban problem predstavljaju infektivne bolesti, uzrokovane
raznim bakterijama. Većina bakterija, koje uzrokuju bolesti kod riba
su normalni stanovnici vodenih sistema, i obično ne uzrokuju bolesti,
odnosno (kao takve) ne predstavljaju problem. Međutim, kada su ribe
izložene stresu, sa jednim od već navedenih faktora, isti mogu ugroziti
imuni sistem jedinke, a usled toga olakšati rast bakterija, te tako povećati rizik za nastajanje bolesti.
Za lečenje bakterijskih infekcija koriste se antimikrobni lekovi, koji imaju veliki značaj u upravljanju zdravljem riba. Efikasnost antimikrobnih lekova u uklanjanju raznih infektivnih bolesti kod riba, zavisi
od više faktora, odnosno ispunjenja više uslova, a to su: a) da li je zaista prisutna bakterijska infekcija? b) da li su identifikovane bakterije
osetljive na izabrani antibiotik? c) da li je lek pravilno doziran i primenjen u odgovarajućim intervalima? i d) da li su dodatni stresovi uklonjeni ili smanjeni?
AB  - Fish production has increased dramatically around the world and occupies an
increasing share (and thus importance) in the total production of food of animal origin. In
order to ensure such a large production, it is necessary to reduce the harmful impact of
numerous environmental factors, and above all stress, drastic changes in temperature,
microorganisms, as well as various chemical substances that can endanger the life of fish. Of all the listed factors, infectious diseases caused by various bacteria are a special
problem. Most bacteria that cause disease in fish are normal inhabitants of aquatic systems,
and usually do not cause disease, or (as such) are not a problem. However, when fish
are exposed to stress, with one of the already mentioned factors, they can endanger the
individual’s immune system, and consequently facilitate the growth of bacteria, and thus
increase the risk of developing the disease.
Antimicrobial drugs, which are of great importance in managing fish health are
used to treat bacterial infections. The effectiveness of antimicrobial drugs in eliminating
various infectious diseases in fish depends on several factors, ie the fulfillment of several
conditions: a) is a bacterial infection really present? b) are the identified bacteria sensitive
to the chosen antibiotic? c) is the drug properly dosed and administered at appropriate
intervals? and d) have additional stresses been removed or reduced?
PB  - Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - Zbornik radova - XLIII seminar inovacija znanja veterinara
T1  - Specifičnost primene antimikrobnih lekova kod riba
T1  - Specificity of application of antimicrobial drugs in fish
SP  - 93
EP  - 106
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2420
ER  - 

@conference{
author = "Ćupić, Vitomir and Ivanović, Saša and Borozan, Sunčica and Prevendar Crnić, Andreja and Mujezinović, Indira and Žugić, Gordana and Velev, Romel",
year = "2022",
abstract = "Proizvodnja ribe dramatično je porasla širom sveta i zauzima sve
veći udeo (a time i značaj) u ukupnoj proizvodnji hrane animalnog porekla. Da bi se osigurala ovako velika proizvodnja, treba umanjiti štetni
uticaj brojnih faktora spoljašnje sredine, a pre svega stresova, drastičnih promena u temperaturi, mikroorganizama, kao i raznih hemijskih
supstancija, koje mogu itekako ugroziti život ribe. Od svih nabrojanih
faktora poseban problem predstavljaju infektivne bolesti, uzrokovane
raznim bakterijama. Većina bakterija, koje uzrokuju bolesti kod riba
su normalni stanovnici vodenih sistema, i obično ne uzrokuju bolesti,
odnosno (kao takve) ne predstavljaju problem. Međutim, kada su ribe
izložene stresu, sa jednim od već navedenih faktora, isti mogu ugroziti
imuni sistem jedinke, a usled toga olakšati rast bakterija, te tako povećati rizik za nastajanje bolesti.
Za lečenje bakterijskih infekcija koriste se antimikrobni lekovi, koji imaju veliki značaj u upravljanju zdravljem riba. Efikasnost antimikrobnih lekova u uklanjanju raznih infektivnih bolesti kod riba, zavisi
od više faktora, odnosno ispunjenja više uslova, a to su: a) da li je zaista prisutna bakterijska infekcija? b) da li su identifikovane bakterije
osetljive na izabrani antibiotik? c) da li je lek pravilno doziran i primenjen u odgovarajućim intervalima? i d) da li su dodatni stresovi uklonjeni ili smanjeni?, Fish production has increased dramatically around the world and occupies an
increasing share (and thus importance) in the total production of food of animal origin. In
order to ensure such a large production, it is necessary to reduce the harmful impact of
numerous environmental factors, and above all stress, drastic changes in temperature,
microorganisms, as well as various chemical substances that can endanger the life of fish. Of all the listed factors, infectious diseases caused by various bacteria are a special
problem. Most bacteria that cause disease in fish are normal inhabitants of aquatic systems,
and usually do not cause disease, or (as such) are not a problem. However, when fish
are exposed to stress, with one of the already mentioned factors, they can endanger the
individual’s immune system, and consequently facilitate the growth of bacteria, and thus
increase the risk of developing the disease.
Antimicrobial drugs, which are of great importance in managing fish health are
used to treat bacterial infections. The effectiveness of antimicrobial drugs in eliminating
various infectious diseases in fish depends on several factors, ie the fulfillment of several
conditions: a) is a bacterial infection really present? b) are the identified bacteria sensitive
to the chosen antibiotic? c) is the drug properly dosed and administered at appropriate
intervals? and d) have additional stresses been removed or reduced?",
publisher = "Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "Zbornik radova - XLIII seminar inovacija znanja veterinara",
title = "Specifičnost primene antimikrobnih lekova kod riba, Specificity of application of antimicrobial drugs in fish",
pages = "93-106",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2420"
}

Ćupić, V., Ivanović, S., Borozan, S., Prevendar Crnić, A., Mujezinović, I., Žugić, G.,& Velev, R.. (2022). Specifičnost primene antimikrobnih lekova kod riba. in Zbornik radova - XLIII seminar inovacija znanja veterinara
Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 93-106.
https://hdl.handle.net/21.15107/rcub_veterinar_2420

Ćupić V, Ivanović S, Borozan S, Prevendar Crnić A, Mujezinović I, Žugić G, Velev R. Specifičnost primene antimikrobnih lekova kod riba. in Zbornik radova - XLIII seminar inovacija znanja veterinara. 2022;:93-106.
https://hdl.handle.net/21.15107/rcub_veterinar_2420 .

Ćupić, Vitomir, Ivanović, Saša, Borozan, Sunčica, Prevendar Crnić, Andreja, Mujezinović, Indira, Žugić, Gordana, Velev, Romel, "Specifičnost primene antimikrobnih lekova kod riba" in Zbornik radova - XLIII seminar inovacija znanja veterinara (2022):93-106,
https://hdl.handle.net/21.15107/rcub_veterinar_2420 .

TY  - CONF
AU  - Ćupić, Vitomir
AU  - Ivanović, Saša
AU  - Borozan, Sunčica
AU  - Prevendar Crnić, Andreja
AU  - Mujezinović, Indira
AU  - Žugić, Gordana
AU  - Velev, Romel
AU  - Ćupić Miladinović, Dejana
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2693
AB  - Poznato je da su brojni pesticidi kroz istoriju imali veliki značaj u zaštiti zdravlja ljudi i životinja. Oni su suzbijanjem i uništavanjem, kako uzročnika, tako i prenosilaca bolesti spasli milione života i isto tako, znatno uvećali prinose poljoprivrednih kultura. Međutim, poslednjnih godina čovek postaje sve svesniji da njegova okolina iz dana u dan postaje sve više zagađena hemikalijama koje mogu delovati štetno, kako na samog čoveka, tako i na životinje i biljke. Među ovim hemikalijama značajno mesto zauzima¬ju pesticidi. Neki od njih su zbog svojih toksičnih efekata (organohlorni insekticidi) već povučeni iz upotrebe, a slična sudbina čeka i neke druge pecticide, a pre svega one, koji su organofosforne građe. 
Odavno je poznato da su mnoge hemikalije toksične za ribe, od kojih posebno tre¬ba spomenuti amonijak, fenole, cijanide i soli nekih teških metala. Takođe i druge hemi¬kalije, koje su se ranije koristile ili se još uvek koriste kao pesticidi, kao što su: olovni-ar¬senat, bakar-sulfat, natrijum-arsenit, natrijum-cijanid, organohlorni insekticidi, orga¬nofosforni insekticidi, karbamati, piretroidi i fenolne smeše su takođe toksični za ribe. Pored ovih su i prirodna organska jedinjenja dobijena iz biljaka, kao što su buhač, deris i duvan, široko korišćena kao insekticidi. Iz buhača, odnosno cveta ove biljke (Chrysan¬themum cinerariaefolium treviranus) izolovano je više jedinjenja (piretrini) sa insekti¬cidnim delovanjem, za koje je poznato da su visoko toksični za ribe. Biljke rodova Derris ili Lonchocarpus sadrže aktivnu supstanciju rotenon, koja je ekstremno toksična za ribe i od davnina je poznata kao otrov za ribe. Ribe su takođe podložne štetnom delovanju cigareta. Nikotin, aktivni sastojak biljke Nicotiana tobacum, je toksičan za većinu riba. Naime, nikotin i druge toksične supstancije iz dima cigarete, se lako rastvaraju u vodi, pa tako i male količine mogu biti veoma štetne, pa čak i smrtonosne za ribu. 
Cilj ovog rada je da se iznošenjem najvažnijih podataka o toksičnom delovanju pe¬sticida na ribe, bar delom smanji broj trovanja ovih životinja raznim pesticidima, a time i zagađenje životne sredine.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 32. Savetovanje veterinara Srbije,Zlatibor, 9–12. septembar 2021
T1  - Pesticidi toksični za ribe
SP  - 264
EP  - 274
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2693
ER  - 

@conference{
author = "Ćupić, Vitomir and Ivanović, Saša and Borozan, Sunčica and Prevendar Crnić, Andreja and Mujezinović, Indira and Žugić, Gordana and Velev, Romel and Ćupić Miladinović, Dejana",
year = "2021",
abstract = "Poznato je da su brojni pesticidi kroz istoriju imali veliki značaj u zaštiti zdravlja ljudi i životinja. Oni su suzbijanjem i uništavanjem, kako uzročnika, tako i prenosilaca bolesti spasli milione života i isto tako, znatno uvećali prinose poljoprivrednih kultura. Međutim, poslednjnih godina čovek postaje sve svesniji da njegova okolina iz dana u dan postaje sve više zagađena hemikalijama koje mogu delovati štetno, kako na samog čoveka, tako i na životinje i biljke. Među ovim hemikalijama značajno mesto zauzima¬ju pesticidi. Neki od njih su zbog svojih toksičnih efekata (organohlorni insekticidi) već povučeni iz upotrebe, a slična sudbina čeka i neke druge pecticide, a pre svega one, koji su organofosforne građe. 
Odavno je poznato da su mnoge hemikalije toksične za ribe, od kojih posebno tre¬ba spomenuti amonijak, fenole, cijanide i soli nekih teških metala. Takođe i druge hemi¬kalije, koje su se ranije koristile ili se još uvek koriste kao pesticidi, kao što su: olovni-ar¬senat, bakar-sulfat, natrijum-arsenit, natrijum-cijanid, organohlorni insekticidi, orga¬nofosforni insekticidi, karbamati, piretroidi i fenolne smeše su takođe toksični za ribe. Pored ovih su i prirodna organska jedinjenja dobijena iz biljaka, kao što su buhač, deris i duvan, široko korišćena kao insekticidi. Iz buhača, odnosno cveta ove biljke (Chrysan¬themum cinerariaefolium treviranus) izolovano je više jedinjenja (piretrini) sa insekti¬cidnim delovanjem, za koje je poznato da su visoko toksični za ribe. Biljke rodova Derris ili Lonchocarpus sadrže aktivnu supstanciju rotenon, koja je ekstremno toksična za ribe i od davnina je poznata kao otrov za ribe. Ribe su takođe podložne štetnom delovanju cigareta. Nikotin, aktivni sastojak biljke Nicotiana tobacum, je toksičan za većinu riba. Naime, nikotin i druge toksične supstancije iz dima cigarete, se lako rastvaraju u vodi, pa tako i male količine mogu biti veoma štetne, pa čak i smrtonosne za ribu. 
Cilj ovog rada je da se iznošenjem najvažnijih podataka o toksičnom delovanju pe¬sticida na ribe, bar delom smanji broj trovanja ovih životinja raznim pesticidima, a time i zagađenje životne sredine.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "32. Savetovanje veterinara Srbije,Zlatibor, 9–12. septembar 2021",
title = "Pesticidi toksični za ribe",
pages = "264-274",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2693"
}

Ćupić, V., Ivanović, S., Borozan, S., Prevendar Crnić, A., Mujezinović, I., Žugić, G., Velev, R.,& Ćupić Miladinović, D.. (2021). Pesticidi toksični za ribe. in 32. Savetovanje veterinara Srbije,Zlatibor, 9–12. septembar 2021
Beograd : Srpsko veterinarsko društvo., 264-274.
https://hdl.handle.net/21.15107/rcub_veterinar_2693

Ćupić V, Ivanović S, Borozan S, Prevendar Crnić A, Mujezinović I, Žugić G, Velev R, Ćupić Miladinović D. Pesticidi toksični za ribe. in 32. Savetovanje veterinara Srbije,Zlatibor, 9–12. septembar 2021. 2021;:264-274.
https://hdl.handle.net/21.15107/rcub_veterinar_2693 .

Ćupić, Vitomir, Ivanović, Saša, Borozan, Sunčica, Prevendar Crnić, Andreja, Mujezinović, Indira, Žugić, Gordana, Velev, Romel, Ćupić Miladinović, Dejana, "Pesticidi toksični za ribe" in 32. Savetovanje veterinara Srbije,Zlatibor, 9–12. septembar 2021 (2021):264-274,
https://hdl.handle.net/21.15107/rcub_veterinar_2693 .

TY  - GEN
AU  - Ćupić, Vitomir
AU  - Ivanović, Saša
AU  - Borozan, Sunčica
AU  - Prevendar Crnić, Andreja
AU  - Mujezinović, Indira
AU  - Žugić, Gordana
AU  - Velev, Romel
AU  - Ćupić Miladinović, Dejana
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3167
AB  - U poslednje vreme, proizvodnja ribe je dramatično porasla širom sveta i zauzima
sve veći udeo (a time i značaj) u ukupnoj proizvodnji hrane animalnog porekla. Da bi
se osigurala ovako velika proizvodnja, treba umanjiti štetni uticaj brojnih faktora spoljašnje
sredine, a pre svega stresova, drastičnih promena u temperaturi, mikroorganizama,
kao i različitih hemijskih supstancija, koje mogu itekako ugroziti život ribe. Od
svih nabrojanih faktora, poseban problem predstavljaju infektivne bolesti, uzrokovane
bakterijama. Većina bakterija, koje uzrokuju bolesti riba su normalni stanovnici vodenih
sistema i obično ne uzrokuju bolesti, odnosno (kao takve) ne predstavljaju problem.
Međutim, kada su ribe izložene stresu, sa jednim od već navedenih faktora (promena
temperature, loš kvalitet vode, nedavni transport ili rukovanje), mogu ugroziti imunski
sistem jedinke, a usled toga favorizovati rast bakterija, čime se svakako povećava rizik
za nastajanje bolesti.
Za lečenje bakterijskih infekcija koriste se antimikrobni lekovi koji su veoma korisni
i imaju veliki značaj u upravljanju zdravljem riba. Većina autora tvrdi da su antimikrobni
lekovi samo „alat“, a ne i „magijski meci“, kako ih je još odavno nazvao Pol Erlih.
Sposobnost antimikrobnih lekova da pomognu u uklanjanju infektivnih bolesti riba, zavisi
od više faktora. Pitanja na koja je potrebno dati odgovore su: a) Da li je zaista prisutna
bakterijska infekcija? b) Da li su identifikovane bakterije osetljive na izabrani antibiotik?
c) Da li je lek pravilno doziran i primenjen u odgovarajućim intervalima? i d)
Da li su dodatni stresovi uklonjeni ili smanjeni?
Pored toga, treba istaći da antimikrobni lekovi, sami po sebi, ne leče infekcije riba.
Ovi lekovi zapravo samo kontrolišu rast populacije bakterija kod riba dovoljno dugo da
ih potom imunski sistem ribe može eliminisati.
U ovom radu su prikazane osnovne karakteristike najvažnijih antimikrobnih lekova,
koji se koriste u lečenju bolesti riba.
PB  - Beograd : Srpsko veterinarsko društvo
T2  - 32. Savetovanje veterinara Srbije, Zlatibor, 9 – 12. septembar 2021
T1  - Primena antimikrobnih lekova kod riba
SP  - 245
EP  - 257
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3167
ER  - 

@misc{
author = "Ćupić, Vitomir and Ivanović, Saša and Borozan, Sunčica and Prevendar Crnić, Andreja and Mujezinović, Indira and Žugić, Gordana and Velev, Romel and Ćupić Miladinović, Dejana",
year = "2021",
abstract = "U poslednje vreme, proizvodnja ribe je dramatično porasla širom sveta i zauzima
sve veći udeo (a time i značaj) u ukupnoj proizvodnji hrane animalnog porekla. Da bi
se osigurala ovako velika proizvodnja, treba umanjiti štetni uticaj brojnih faktora spoljašnje
sredine, a pre svega stresova, drastičnih promena u temperaturi, mikroorganizama,
kao i različitih hemijskih supstancija, koje mogu itekako ugroziti život ribe. Od
svih nabrojanih faktora, poseban problem predstavljaju infektivne bolesti, uzrokovane
bakterijama. Većina bakterija, koje uzrokuju bolesti riba su normalni stanovnici vodenih
sistema i obično ne uzrokuju bolesti, odnosno (kao takve) ne predstavljaju problem.
Međutim, kada su ribe izložene stresu, sa jednim od već navedenih faktora (promena
temperature, loš kvalitet vode, nedavni transport ili rukovanje), mogu ugroziti imunski
sistem jedinke, a usled toga favorizovati rast bakterija, čime se svakako povećava rizik
za nastajanje bolesti.
Za lečenje bakterijskih infekcija koriste se antimikrobni lekovi koji su veoma korisni
i imaju veliki značaj u upravljanju zdravljem riba. Većina autora tvrdi da su antimikrobni
lekovi samo „alat“, a ne i „magijski meci“, kako ih je još odavno nazvao Pol Erlih.
Sposobnost antimikrobnih lekova da pomognu u uklanjanju infektivnih bolesti riba, zavisi
od više faktora. Pitanja na koja je potrebno dati odgovore su: a) Da li je zaista prisutna
bakterijska infekcija? b) Da li su identifikovane bakterije osetljive na izabrani antibiotik?
c) Da li je lek pravilno doziran i primenjen u odgovarajućim intervalima? i d)
Da li su dodatni stresovi uklonjeni ili smanjeni?
Pored toga, treba istaći da antimikrobni lekovi, sami po sebi, ne leče infekcije riba.
Ovi lekovi zapravo samo kontrolišu rast populacije bakterija kod riba dovoljno dugo da
ih potom imunski sistem ribe može eliminisati.
U ovom radu su prikazane osnovne karakteristike najvažnijih antimikrobnih lekova,
koji se koriste u lečenju bolesti riba.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "32. Savetovanje veterinara Srbije, Zlatibor, 9 – 12. septembar 2021",
title = "Primena antimikrobnih lekova kod riba",
pages = "245-257",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3167"
}

Ćupić, V., Ivanović, S., Borozan, S., Prevendar Crnić, A., Mujezinović, I., Žugić, G., Velev, R.,& Ćupić Miladinović, D.. (2021). Primena antimikrobnih lekova kod riba. in 32. Savetovanje veterinara Srbije, Zlatibor, 9 – 12. septembar 2021
Beograd : Srpsko veterinarsko društvo., 245-257.
https://hdl.handle.net/21.15107/rcub_veterinar_3167

Ćupić V, Ivanović S, Borozan S, Prevendar Crnić A, Mujezinović I, Žugić G, Velev R, Ćupić Miladinović D. Primena antimikrobnih lekova kod riba. in 32. Savetovanje veterinara Srbije, Zlatibor, 9 – 12. septembar 2021. 2021;:245-257.
https://hdl.handle.net/21.15107/rcub_veterinar_3167 .

Ćupić, Vitomir, Ivanović, Saša, Borozan, Sunčica, Prevendar Crnić, Andreja, Mujezinović, Indira, Žugić, Gordana, Velev, Romel, Ćupić Miladinović, Dejana, "Primena antimikrobnih lekova kod riba" in 32. Savetovanje veterinara Srbije, Zlatibor, 9 – 12. septembar 2021 (2021):245-257,
https://hdl.handle.net/21.15107/rcub_veterinar_3167 .

TY  - CONF
AU  - Velev, Romel
AU  - Trajkovski, F.
AU  - Krleska-Veleva, Nataša
AU  - Ćupić, Vitomir
AU  - Ćupić Miladinović, Dejana
PY  - 2018
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1674
AB  - Introduction: 3D printing has numerous applications and has gained
much interest in the medical world. The current medical and veterinary medicine uses of 3D printing can be organized into several
broad categories: tissue and organs fabrication; creating of implants,
prosthetics and anatomical models; and pharmaceutical research
concerning drug discovery, delivery, and dosage forms. The purpose
of our work was to gain a better perspective of how 3D printing
technology works by getting a first-hand look at this process and
then strategize ways that this technology can potentially be used in
development of animal health products.
What Is 3D Printing and How Does It Work?: 3D printing is a type of additive manufacturing. It is a process that creates a three-dimensional
object by building successive layers of raw material. Objects are produced from a digital 3D file, such as a computer-aided design (CAD)
drawing or a Magnetic Resonance Image. 3D printing can create
a solid object of virtually any shape and can use an assortment of
starting materials, including plastic, metal, ceramic, tissue and organ
cells.
Exploring the Possibilities of 3D Printing in Development of Animal
Health Products: The purpose of veterinary drug development in the
future should be production of personalized animal health products
that can be achieved through the application of 3D printing. The
application of 3D printing in veterinary medicine, including tablets, holds promise for made-to-order drugs, and removes mass product
manufacturing from the production line, although the technology
in pharmaceutical industry is still in infancy. 3D printing promises
a future of drugs printed on demand, to custom doses, especially in
companion animals.
Conclusions: Prototype projects demonstrated that it is possible to
use 3D printing techniques to generate and manufacture chemical
compounds. In applying this technology to animal health products,
the first generation technology is already a reality. Proof of this is recently approved 3D-printed oral drug Spritam (levetiracetam) by US
FDA in human medicine. The second-generation efforts will involve
getting a digital prescription, buying the “blueprint” and chemical
“materials” needed, and then printing the drug with the software and
a 3D molecular printer. Hence, 3D drug printing will have important
repercussions in the realm of distribution of animal health products.
However, even more profound are the eventual implications for new
drug discovery and personalized therapy for animals. Indeed, thirdgeneration 3D drug printing would entail the creation of new drugs
that maximize efficacy and minimize toxicity. But there are a number
of questions. Approval of a 3D-printed veterinary drugs opens up
a new world of customised medication, but also the possibility of
counterfeit drugs, mislabelling and a regulatory vacuum.
PB  - Wiley, Hoboken
C3  - Journal of Veterinary Pharmacology and Therapeutics
T1  - 3D printing and the future of development of animal health products
VL  - 41
SP  - 68
EP  - 69
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_1674
ER  - 

@conference{
author = "Velev, Romel and Trajkovski, F. and Krleska-Veleva, Nataša and Ćupić, Vitomir and Ćupić Miladinović, Dejana",
year = "2018",
abstract = "Introduction: 3D printing has numerous applications and has gained
much interest in the medical world. The current medical and veterinary medicine uses of 3D printing can be organized into several
broad categories: tissue and organs fabrication; creating of implants,
prosthetics and anatomical models; and pharmaceutical research
concerning drug discovery, delivery, and dosage forms. The purpose
of our work was to gain a better perspective of how 3D printing
technology works by getting a first-hand look at this process and
then strategize ways that this technology can potentially be used in
development of animal health products.
What Is 3D Printing and How Does It Work?: 3D printing is a type of additive manufacturing. It is a process that creates a three-dimensional
object by building successive layers of raw material. Objects are produced from a digital 3D file, such as a computer-aided design (CAD)
drawing or a Magnetic Resonance Image. 3D printing can create
a solid object of virtually any shape and can use an assortment of
starting materials, including plastic, metal, ceramic, tissue and organ
cells.
Exploring the Possibilities of 3D Printing in Development of Animal
Health Products: The purpose of veterinary drug development in the
future should be production of personalized animal health products
that can be achieved through the application of 3D printing. The
application of 3D printing in veterinary medicine, including tablets, holds promise for made-to-order drugs, and removes mass product
manufacturing from the production line, although the technology
in pharmaceutical industry is still in infancy. 3D printing promises
a future of drugs printed on demand, to custom doses, especially in
companion animals.
Conclusions: Prototype projects demonstrated that it is possible to
use 3D printing techniques to generate and manufacture chemical
compounds. In applying this technology to animal health products,
the first generation technology is already a reality. Proof of this is recently approved 3D-printed oral drug Spritam (levetiracetam) by US
FDA in human medicine. The second-generation efforts will involve
getting a digital prescription, buying the “blueprint” and chemical
“materials” needed, and then printing the drug with the software and
a 3D molecular printer. Hence, 3D drug printing will have important
repercussions in the realm of distribution of animal health products.
However, even more profound are the eventual implications for new
drug discovery and personalized therapy for animals. Indeed, thirdgeneration 3D drug printing would entail the creation of new drugs
that maximize efficacy and minimize toxicity. But there are a number
of questions. Approval of a 3D-printed veterinary drugs opens up
a new world of customised medication, but also the possibility of
counterfeit drugs, mislabelling and a regulatory vacuum.",
publisher = "Wiley, Hoboken",
journal = "Journal of Veterinary Pharmacology and Therapeutics",
title = "3D printing and the future of development of animal health products",
volume = "41",
pages = "68-69",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_1674"
}

Velev, R., Trajkovski, F., Krleska-Veleva, N., Ćupić, V.,& Ćupić Miladinović, D.. (2018). 3D printing and the future of development of animal health products. in Journal of Veterinary Pharmacology and Therapeutics
Wiley, Hoboken., 41, 68-69.
https://hdl.handle.net/21.15107/rcub_veterinar_1674

Velev R, Trajkovski F, Krleska-Veleva N, Ćupić V, Ćupić Miladinović D. 3D printing and the future of development of animal health products. in Journal of Veterinary Pharmacology and Therapeutics. 2018;41:68-69.
https://hdl.handle.net/21.15107/rcub_veterinar_1674 .

Velev, Romel, Trajkovski, F., Krleska-Veleva, Nataša, Ćupić, Vitomir, Ćupić Miladinović, Dejana, "3D printing and the future of development of animal health products" in Journal of Veterinary Pharmacology and Therapeutics, 41 (2018):68-69,
https://hdl.handle.net/21.15107/rcub_veterinar_1674 .

TY  - CONF
AU  - Ćupić, Vitomir
AU  - Jović, Slavoljub
AU  - Ristić, Gordana
AU  - Vakanjac, Slobodanka
AU  - Velev, Romel
AU  - Ćupić Miladinović, Dejana
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1292
AB  - INTRODUCTION
Process of farrowing in sows on farms represents the most delicate stage in the production of piglets. It is best to finish the
delivery as soon as possible, because in this way sows recover
as soon as possible, and allows the piglets to suck colostrum.
In order to achieve the shortest duration of parturation, in the
control farrowing most often are applied uterotonics, such as
oxytocin in combination with drugs for induction of parturition
(prostaglandin analogues, PGF2-alpha).
The aim of this study was to examine the extent to which prostaglandins F2-alfa (applied alone or in combination with oxytocin) influence on the duration of parturition, and the
number of liveborn piglets.
MATERIALS AND METHODS
The experiments were performed in vivo on 133 pregnant
sows, breeds Landrace-Yorkshire, which were divided into nine
groups. The animals of the first three groups were administered
prostaglandin F2-alfa (Dinoprost), i.m. at a single dose of 2 ml,
at 112 days of gestation and once (after farrowing fifth pigletsecond group) oxytocin (Oxytokel), i.m., at a dose of 2 ml per
animal (eq. 20 units per animal) or twice (after farrowing fifth
and tenth piglet-third group) oxytocin, i.m., at a dose of 2 ml
per animal (eq. 20 units per animal) first time and then
1.5 ml per animal (eq. 15 units per animal) second time. All
of this was done at 113 days (groups IV, V, VI) and at
114 days of gestation (groups VII, VIII, IX).
RESULTS
The obtained results showed that average duration of farrowing was the shortest (4.56 h) in sows which is applied only
prostaglandin at 114 days of gestation, and the longest
(7.17 h) in sows treated with prostaglandin at 112 day of gestation with twofold application of oxytocin. The largest number
of newborn piglets (20, 47) have been reported in sows which
were treated with prostaglandin at 113th day of pregnancy in
combination with twofold application of oxytocin.
CONCLUSION
On the base of all results it may be concluded that the best
effect is achieved (duration of partus and number of newborn
piglet) when prostaglandin applied in combination of oxytocin
(twofold) at 113th day of pregnancy.
PB  - Wiley-Blackwell, Hoboken
C3  - Journal of Veterinary Pharmacology and Therapeutics
T1  - Effect of combined application of prostaglandins and oxytocin on the duration of parturition and number of newborn piglets of sows
VL  - 38
SP  - 151
EP  - 151
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_1292
ER  - 

@conference{
author = "Ćupić, Vitomir and Jović, Slavoljub and Ristić, Gordana and Vakanjac, Slobodanka and Velev, Romel and Ćupić Miladinović, Dejana",
year = "2015",
abstract = "INTRODUCTION
Process of farrowing in sows on farms represents the most delicate stage in the production of piglets. It is best to finish the
delivery as soon as possible, because in this way sows recover
as soon as possible, and allows the piglets to suck colostrum.
In order to achieve the shortest duration of parturation, in the
control farrowing most often are applied uterotonics, such as
oxytocin in combination with drugs for induction of parturition
(prostaglandin analogues, PGF2-alpha).
The aim of this study was to examine the extent to which prostaglandins F2-alfa (applied alone or in combination with oxytocin) influence on the duration of parturition, and the
number of liveborn piglets.
MATERIALS AND METHODS
The experiments were performed in vivo on 133 pregnant
sows, breeds Landrace-Yorkshire, which were divided into nine
groups. The animals of the first three groups were administered
prostaglandin F2-alfa (Dinoprost), i.m. at a single dose of 2 ml,
at 112 days of gestation and once (after farrowing fifth pigletsecond group) oxytocin (Oxytokel), i.m., at a dose of 2 ml per
animal (eq. 20 units per animal) or twice (after farrowing fifth
and tenth piglet-third group) oxytocin, i.m., at a dose of 2 ml
per animal (eq. 20 units per animal) first time and then
1.5 ml per animal (eq. 15 units per animal) second time. All
of this was done at 113 days (groups IV, V, VI) and at
114 days of gestation (groups VII, VIII, IX).
RESULTS
The obtained results showed that average duration of farrowing was the shortest (4.56 h) in sows which is applied only
prostaglandin at 114 days of gestation, and the longest
(7.17 h) in sows treated with prostaglandin at 112 day of gestation with twofold application of oxytocin. The largest number
of newborn piglets (20, 47) have been reported in sows which
were treated with prostaglandin at 113th day of pregnancy in
combination with twofold application of oxytocin.
CONCLUSION
On the base of all results it may be concluded that the best
effect is achieved (duration of partus and number of newborn
piglet) when prostaglandin applied in combination of oxytocin
(twofold) at 113th day of pregnancy.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Veterinary Pharmacology and Therapeutics",
title = "Effect of combined application of prostaglandins and oxytocin on the duration of parturition and number of newborn piglets of sows",
volume = "38",
pages = "151-151",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_1292"
}

Ćupić, V., Jović, S., Ristić, G., Vakanjac, S., Velev, R.,& Ćupić Miladinović, D.. (2015). Effect of combined application of prostaglandins and oxytocin on the duration of parturition and number of newborn piglets of sows. in Journal of Veterinary Pharmacology and Therapeutics
Wiley-Blackwell, Hoboken., 38, 151-151.
https://hdl.handle.net/21.15107/rcub_veterinar_1292

Ćupić V, Jović S, Ristić G, Vakanjac S, Velev R, Ćupić Miladinović D. Effect of combined application of prostaglandins and oxytocin on the duration of parturition and number of newborn piglets of sows. in Journal of Veterinary Pharmacology and Therapeutics. 2015;38:151-151.
https://hdl.handle.net/21.15107/rcub_veterinar_1292 .

Ćupić, Vitomir, Jović, Slavoljub, Ristić, Gordana, Vakanjac, Slobodanka, Velev, Romel, Ćupić Miladinović, Dejana, "Effect of combined application of prostaglandins and oxytocin on the duration of parturition and number of newborn piglets of sows" in Journal of Veterinary Pharmacology and Therapeutics, 38 (2015):151-151,
https://hdl.handle.net/21.15107/rcub_veterinar_1292 .

TY  - CONF
AU  - Velev, Romel
AU  - Krleska-Veleva, Nataša
AU  - Ćupić, Vitomir
AU  - Ćupić Miladinović, Dejana
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1291
AB  - INTRODUCTION
Animal medicines play an important role in the control and
prevention of disease but have the potential to cause harm if
not used properly. The use of veterinary medicines (VM) can
sometimes result in residues in foods taken from the treated
animals and can seriously endangered the health of people as
potential consumers. Therefore, the significance of control of
the VM in these animals is exceptionally high. These include
statutory controls on the authorisation, distribution and use of
such medicines. The aim of this paper is to show legal status
regarding distribution/dispensing and administration of VM in
Macedonia (RM) in order to identify legal weaknesses.
MATERIALS AND METHODS
National Law on VM (Article 47) provides legal basis for distribution of VM in categories. Following evaluation of scientific
data provided by the MAH, for each VM is granted a specific
distribution category by the Food and Veterinary Agency
(FVA) when it is for first time authorised. The data was collected from the web site of sector for Public Health in FVA and
was compared with Veterinary Medicines Regulations in other
countries.
RESULTS
All VM in the RM are assigned into one of six distribution categories. Only veterinary surgeons (VS) are entitled to prescribe
VM and they must be dispensed from registered premises. The
highest level of control is the VM intended for food production
animals which can be used only in veterinary premisses by the
VS or under their direct responsibility. This would include VM
containing controlled drugs and those intended for administration only following a diagnosis and clinical assessment of the
animal(s). VM which can be dispensed in veterinary pharmacies only by written prescription is intended for food production
animals but is not required a clinical assessment. VM intended
for non-food production animals may be supplied by any retailer without any restrictions, or provision of advice.CONCLUSIONS
Distribution categories provide controls on the supply of veterinary medicines to help ensure that appropriate advice is given
at the point of sale so that products can be used safely and
effectively. Also it is a practical tool for identification of different groups of VM for the veterinary practitioners as well as all
subjects involved in production, trade and distribution of VM.
The results obtained given an overall picture of trends in the
use of VM in RM and allows comparison of such trends in
other countries.
PB  - Wiley-Blackwell, Hoboken
C3  - Journal of Veterinary Pharmacology and Therapeutics
T1  - Legal status regarding distribution/dispensing and administration of veterinary medicines in Republic of Macedonia
VL  - 38
SP  - 151
EP  - 152
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_1291
ER  - 

@conference{
author = "Velev, Romel and Krleska-Veleva, Nataša and Ćupić, Vitomir and Ćupić Miladinović, Dejana",
year = "2015",
abstract = "INTRODUCTION
Animal medicines play an important role in the control and
prevention of disease but have the potential to cause harm if
not used properly. The use of veterinary medicines (VM) can
sometimes result in residues in foods taken from the treated
animals and can seriously endangered the health of people as
potential consumers. Therefore, the significance of control of
the VM in these animals is exceptionally high. These include
statutory controls on the authorisation, distribution and use of
such medicines. The aim of this paper is to show legal status
regarding distribution/dispensing and administration of VM in
Macedonia (RM) in order to identify legal weaknesses.
MATERIALS AND METHODS
National Law on VM (Article 47) provides legal basis for distribution of VM in categories. Following evaluation of scientific
data provided by the MAH, for each VM is granted a specific
distribution category by the Food and Veterinary Agency
(FVA) when it is for first time authorised. The data was collected from the web site of sector for Public Health in FVA and
was compared with Veterinary Medicines Regulations in other
countries.
RESULTS
All VM in the RM are assigned into one of six distribution categories. Only veterinary surgeons (VS) are entitled to prescribe
VM and they must be dispensed from registered premises. The
highest level of control is the VM intended for food production
animals which can be used only in veterinary premisses by the
VS or under their direct responsibility. This would include VM
containing controlled drugs and those intended for administration only following a diagnosis and clinical assessment of the
animal(s). VM which can be dispensed in veterinary pharmacies only by written prescription is intended for food production
animals but is not required a clinical assessment. VM intended
for non-food production animals may be supplied by any retailer without any restrictions, or provision of advice.CONCLUSIONS
Distribution categories provide controls on the supply of veterinary medicines to help ensure that appropriate advice is given
at the point of sale so that products can be used safely and
effectively. Also it is a practical tool for identification of different groups of VM for the veterinary practitioners as well as all
subjects involved in production, trade and distribution of VM.
The results obtained given an overall picture of trends in the
use of VM in RM and allows comparison of such trends in
other countries.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Veterinary Pharmacology and Therapeutics",
title = "Legal status regarding distribution/dispensing and administration of veterinary medicines in Republic of Macedonia",
volume = "38",
pages = "151-152",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_1291"
}

Velev, R., Krleska-Veleva, N., Ćupić, V.,& Ćupić Miladinović, D.. (2015). Legal status regarding distribution/dispensing and administration of veterinary medicines in Republic of Macedonia. in Journal of Veterinary Pharmacology and Therapeutics
Wiley-Blackwell, Hoboken., 38, 151-152.
https://hdl.handle.net/21.15107/rcub_veterinar_1291

Velev R, Krleska-Veleva N, Ćupić V, Ćupić Miladinović D. Legal status regarding distribution/dispensing and administration of veterinary medicines in Republic of Macedonia. in Journal of Veterinary Pharmacology and Therapeutics. 2015;38:151-152.
https://hdl.handle.net/21.15107/rcub_veterinar_1291 .

Velev, Romel, Krleska-Veleva, Nataša, Ćupić, Vitomir, Ćupić Miladinović, Dejana, "Legal status regarding distribution/dispensing and administration of veterinary medicines in Republic of Macedonia" in Journal of Veterinary Pharmacology and Therapeutics, 38 (2015):151-152,
https://hdl.handle.net/21.15107/rcub_veterinar_1291 .

TY  - CONF
AU  - Ćupić Miladinović, Dejana
AU  - Borozan, Sunčica
AU  - Popović, Z.
AU  - Ćupić, Vitomir
AU  - Velev, Romel
AU  - Antonijević, Biljana
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1301
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - The influence of chlorpyrifos on the activity of butyryilcholinesterase and catalase, as well as concentration of malondialdehyde in plasma of Japanese quail
VL  - 238
IS  - 2
SP  - S111
EP  - S111
DO  - 10.1016/j.toxlet.2015.08.360
ER  - 

@conference{
author = "Ćupić Miladinović, Dejana and Borozan, Sunčica and Popović, Z. and Ćupić, Vitomir and Velev, Romel and Antonijević, Biljana",
year = "2015",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "The influence of chlorpyrifos on the activity of butyryilcholinesterase and catalase, as well as concentration of malondialdehyde in plasma of Japanese quail",
volume = "238",
number = "2",
pages = "S111-S111",
doi = "10.1016/j.toxlet.2015.08.360"
}

Ćupić Miladinović, D., Borozan, S., Popović, Z., Ćupić, V., Velev, R.,& Antonijević, B.. (2015). The influence of chlorpyrifos on the activity of butyryilcholinesterase and catalase, as well as concentration of malondialdehyde in plasma of Japanese quail. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 238(2), S111-S111.
https://doi.org/10.1016/j.toxlet.2015.08.360

Ćupić Miladinović D, Borozan S, Popović Z, Ćupić V, Velev R, Antonijević B. The influence of chlorpyrifos on the activity of butyryilcholinesterase and catalase, as well as concentration of malondialdehyde in plasma of Japanese quail. in Toxicology Letters. 2015;238(2):S111-S111.
doi:10.1016/j.toxlet.2015.08.360 .

Ćupić Miladinović, Dejana, Borozan, Sunčica, Popović, Z., Ćupić, Vitomir, Velev, Romel, Antonijević, Biljana, "The influence of chlorpyrifos on the activity of butyryilcholinesterase and catalase, as well as concentration of malondialdehyde in plasma of Japanese quail" in Toxicology Letters, 238, no. 2 (2015):S111-S111,
https://doi.org/10.1016/j.toxlet.2015.08.360 . .

TY  - JOUR
AU  - Velev, Romel
AU  - Krleska-Veleva, Nataša
AU  - Ćupić, Vitomir
PY  - 2009
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/634
AB  - The term heavy metal refers to a metal that has a relatively high density and is toxic for animal and human organism at low concentrations. Heavy metals are natural components of the Earth's crust. They cannot be degraded or destroyed. To a small extent they enter animal organism via food, drinking water and air. Some heavy metals (e.g cooper, iron, chromium, zinc) are essential in very low concentrations for the survival of all forms of life. These are described as essential trace elements. However, when they are present in greater quantities, like the heavy metals lead, cadmium and mercury which are already toxic in very low concentrations, they can cause metabolic anomalies or poisoning. Heavy metal poisoning of domestic animals could result, for instance, from drinking-water contamination, high ambient air concentrations near emission sources, or intake via the food chain. Heavy metals are dangerous because they tend to bioaccumulate in a biological organism over time. Manifestation of toxicity of individual heavy metals varies considerably, depending on dose and time of exposure, species, gender and environmental and nutritional factors. Large differences exist between the effects of a single exposure to a high concentration, and chronic exposures to lower doses. The aim of this work is to present the source of poisoning and toxicity of some heavy metals (lead, mercury, cadmium, thallium, arsenic), as well as new data about effects of those heavy metals on the health of domestic animals. .
AB  - Termin teški metali odnosi se na metale koji imaju relativno visoku gustoću i koji su toksični za životinjski i ljudski organizam u niskim koncentracijama. Oni su prirodni sastojci zemljine kore, ne mogu biti razgrađeni ili uništeni, a u malim količinama ulaze u životinjski organizam hranom, vodom ili vazduhom. Pojedini teški metali kao bakar, gvožđe, hrom i cink u malim količinama su esencijalni za živi organizam, ipak kada su prisutni u većim količinama remete normalne životne procese, odnosno izazivaju trovanje. Za razliku od njih teški metali kao olovo, kadmijum, živa i talijum nisu esencijalni i toksični su za organizam već u veoma malim količinama. Trovanje domaćih životinja ovim teškim metalima je rezultat njihovog neplaniranog ulaska u životinjski organizam, najčešće preko kontaminirane hrane, vode ili vazduha. Oni imaju tendenciju bioakumulacije u živom organizmu, a pojava manifestnih znakova njihove toksičnosti varira u zavisnosti od prirode hemijskog jedinjenja u kojem se nalaze, zatim količine i vremena izloženosti, životinjske vrste, uzrasta, pola, kao i uticaja okoline i svakako načina ishrane. Kod pojedinih teških metala postoje velike razlike u izazivanju toksičnih efekata, kako posle jednokratnog izlaganja životinja njihovim visokim koncentracijama ili pak izlaganja životinja niskim koncentracijama ovih toksikanata u toku dužeg vremenskog perioda (hronično izlaganje). Cilj ovog rada je da prikaže moguće izvore trovanja i toksičnost pojedinih teških metala (olovo, živa, kadmijum, talijum), kao i novija saznanja o toksičnim efektima ovih metala na zdravlje domaćih životinja.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Poisoning of domestic animals with heavy metals
T1  - Trovanja domaćih životinja teškim metalima
VL  - 63
IS  - 5-6
SP  - 393
EP  - 405
DO  - 10.2298/VETGL0906393V
ER  - 

@article{
author = "Velev, Romel and Krleska-Veleva, Nataša and Ćupić, Vitomir",
year = "2009",
abstract = "The term heavy metal refers to a metal that has a relatively high density and is toxic for animal and human organism at low concentrations. Heavy metals are natural components of the Earth's crust. They cannot be degraded or destroyed. To a small extent they enter animal organism via food, drinking water and air. Some heavy metals (e.g cooper, iron, chromium, zinc) are essential in very low concentrations for the survival of all forms of life. These are described as essential trace elements. However, when they are present in greater quantities, like the heavy metals lead, cadmium and mercury which are already toxic in very low concentrations, they can cause metabolic anomalies or poisoning. Heavy metal poisoning of domestic animals could result, for instance, from drinking-water contamination, high ambient air concentrations near emission sources, or intake via the food chain. Heavy metals are dangerous because they tend to bioaccumulate in a biological organism over time. Manifestation of toxicity of individual heavy metals varies considerably, depending on dose and time of exposure, species, gender and environmental and nutritional factors. Large differences exist between the effects of a single exposure to a high concentration, and chronic exposures to lower doses. The aim of this work is to present the source of poisoning and toxicity of some heavy metals (lead, mercury, cadmium, thallium, arsenic), as well as new data about effects of those heavy metals on the health of domestic animals. ., Termin teški metali odnosi se na metale koji imaju relativno visoku gustoću i koji su toksični za životinjski i ljudski organizam u niskim koncentracijama. Oni su prirodni sastojci zemljine kore, ne mogu biti razgrađeni ili uništeni, a u malim količinama ulaze u životinjski organizam hranom, vodom ili vazduhom. Pojedini teški metali kao bakar, gvožđe, hrom i cink u malim količinama su esencijalni za živi organizam, ipak kada su prisutni u većim količinama remete normalne životne procese, odnosno izazivaju trovanje. Za razliku od njih teški metali kao olovo, kadmijum, živa i talijum nisu esencijalni i toksični su za organizam već u veoma malim količinama. Trovanje domaćih životinja ovim teškim metalima je rezultat njihovog neplaniranog ulaska u životinjski organizam, najčešće preko kontaminirane hrane, vode ili vazduha. Oni imaju tendenciju bioakumulacije u živom organizmu, a pojava manifestnih znakova njihove toksičnosti varira u zavisnosti od prirode hemijskog jedinjenja u kojem se nalaze, zatim količine i vremena izloženosti, životinjske vrste, uzrasta, pola, kao i uticaja okoline i svakako načina ishrane. Kod pojedinih teških metala postoje velike razlike u izazivanju toksičnih efekata, kako posle jednokratnog izlaganja životinja njihovim visokim koncentracijama ili pak izlaganja životinja niskim koncentracijama ovih toksikanata u toku dužeg vremenskog perioda (hronično izlaganje). Cilj ovog rada je da prikaže moguće izvore trovanja i toksičnost pojedinih teških metala (olovo, živa, kadmijum, talijum), kao i novija saznanja o toksičnim efektima ovih metala na zdravlje domaćih životinja.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Poisoning of domestic animals with heavy metals, Trovanja domaćih životinja teškim metalima",
volume = "63",
number = "5-6",
pages = "393-405",
doi = "10.2298/VETGL0906393V"
}

Velev, R., Krleska-Veleva, N.,& Ćupić, V.. (2009). Poisoning of domestic animals with heavy metals. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 63(5-6), 393-405.
https://doi.org/10.2298/VETGL0906393V

Velev R, Krleska-Veleva N, Ćupić V. Poisoning of domestic animals with heavy metals. in Veterinarski Glasnik. 2009;63(5-6):393-405.
doi:10.2298/VETGL0906393V .

Velev, Romel, Krleska-Veleva, Nataša, Ćupić, Vitomir, "Poisoning of domestic animals with heavy metals" in Veterinarski Glasnik, 63, no. 5-6 (2009):393-405,
https://doi.org/10.2298/VETGL0906393V . .

TY  - CONF
AU  - Indira, M.
AU  - Ćupić, Vitomir
AU  - Smajlović, Ahmed
AU  - Muminović, Mehmed
AU  - Velev, Romel
PY  - 2009
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/596
PB  - Wiley-Blackwell Publishing, Inc, Malden
C3  - Journal of Veterinary Pharmacology and Therapeutics
T1  - Identification of histaminic (H1-type) receptors in broiler s small intestine by application of histamine and some of its agonists and antagonists
VL  - 32
SP  - 240
EP  - 241
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_596
ER  - 

@conference{
author = "Indira, M. and Ćupić, Vitomir and Smajlović, Ahmed and Muminović, Mehmed and Velev, Romel",
year = "2009",
publisher = "Wiley-Blackwell Publishing, Inc, Malden",
journal = "Journal of Veterinary Pharmacology and Therapeutics",
title = "Identification of histaminic (H1-type) receptors in broiler s small intestine by application of histamine and some of its agonists and antagonists",
volume = "32",
pages = "240-241",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_596"
}

Indira, M., Ćupić, V., Smajlović, A., Muminović, M.,& Velev, R.. (2009). Identification of histaminic (H1-type) receptors in broiler s small intestine by application of histamine and some of its agonists and antagonists. in Journal of Veterinary Pharmacology and Therapeutics
Wiley-Blackwell Publishing, Inc, Malden., 32, 240-241.
https://hdl.handle.net/21.15107/rcub_veterinar_596

Indira M, Ćupić V, Smajlović A, Muminović M, Velev R. Identification of histaminic (H1-type) receptors in broiler s small intestine by application of histamine and some of its agonists and antagonists. in Journal of Veterinary Pharmacology and Therapeutics. 2009;32:240-241.
https://hdl.handle.net/21.15107/rcub_veterinar_596 .

Indira, M., Ćupić, Vitomir, Smajlović, Ahmed, Muminović, Mehmed, Velev, Romel, "Identification of histaminic (H1-type) receptors in broiler s small intestine by application of histamine and some of its agonists and antagonists" in Journal of Veterinary Pharmacology and Therapeutics, 32 (2009):240-241,
https://hdl.handle.net/21.15107/rcub_veterinar_596 .

TY  - CONF
AU  - Velev, Romel
AU  - Ćupić, Vitomir
AU  - Dobrić, S.
AU  - Krleska-Veleva, N.
PY  - 2005
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/336
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Gastrotoxic effects of NSAIDs and the role of no-donors in gastroprotection
VL  - 158
SP  - S52
EP  - S52
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_336
ER  - 

@conference{
author = "Velev, Romel and Ćupić, Vitomir and Dobrić, S. and Krleska-Veleva, N.",
year = "2005",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Gastrotoxic effects of NSAIDs and the role of no-donors in gastroprotection",
volume = "158",
pages = "S52-S52",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_336"
}

Velev, R., Ćupić, V., Dobrić, S.,& Krleska-Veleva, N.. (2005). Gastrotoxic effects of NSAIDs and the role of no-donors in gastroprotection. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 158, S52-S52.
https://hdl.handle.net/21.15107/rcub_veterinar_336

Velev R, Ćupić V, Dobrić S, Krleska-Veleva N. Gastrotoxic effects of NSAIDs and the role of no-donors in gastroprotection. in Toxicology Letters. 2005;158:S52-S52.
https://hdl.handle.net/21.15107/rcub_veterinar_336 .

Velev, Romel, Ćupić, Vitomir, Dobrić, S., Krleska-Veleva, N., "Gastrotoxic effects of NSAIDs and the role of no-donors in gastroprotection" in Toxicology Letters, 158 (2005):S52-S52,
https://hdl.handle.net/21.15107/rcub_veterinar_336 .

TY  - CONF
AU  - Dobrić, Silva
AU  - Velev, Romel
AU  - Ćupić, Vitomir
AU  - Milovanović, Zoran A.
AU  - Jaćević, Vesna
AU  - Bokonjić, Dubravko
PY  - 2002
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/198
PB  - Savez farmaceutskih udruženja Srbije, Beograd
C3  - Arhiv za farmaciju
T1  - Donors of nitric oxide as potential antiulcer drugs
T1  - Donori azot oksida kao potencijalni antiulkusni lekovi
VL  - 52
IS  - 4
SP  - 632
EP  - 633
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_198
ER  - 

@conference{
author = "Dobrić, Silva and Velev, Romel and Ćupić, Vitomir and Milovanović, Zoran A. and Jaćević, Vesna and Bokonjić, Dubravko",
year = "2002",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Donors of nitric oxide as potential antiulcer drugs, Donori azot oksida kao potencijalni antiulkusni lekovi",
volume = "52",
number = "4",
pages = "632-633",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_198"
}

Dobrić, S., Velev, R., Ćupić, V., Milovanović, Z. A., Jaćević, V.,& Bokonjić, D.. (2002). Donors of nitric oxide as potential antiulcer drugs. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 52(4), 632-633.
https://hdl.handle.net/21.15107/rcub_veterinar_198

Dobrić S, Velev R, Ćupić V, Milovanović ZA, Jaćević V, Bokonjić D. Donors of nitric oxide as potential antiulcer drugs. in Arhiv za farmaciju. 2002;52(4):632-633.
https://hdl.handle.net/21.15107/rcub_veterinar_198 .

Dobrić, Silva, Velev, Romel, Ćupić, Vitomir, Milovanović, Zoran A., Jaćević, Vesna, Bokonjić, Dubravko, "Donors of nitric oxide as potential antiulcer drugs" in Arhiv za farmaciju, 52, no. 4 (2002):632-633,
https://hdl.handle.net/21.15107/rcub_veterinar_198 .