Sladojević, Željko

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  • Sladojević, Željko (23)

Author's Bibliography

Epidemiology and risk factors of trichinellosis in Bosnia and Herzegovina from 1961 to 2021

Despotović, Darko; Nenadović, Katarina; Sladojević, Željko; Dimitrijević, Sanda; Ilić, Tamara

(Springer, 2023)

TY  - JOUR
AU  - Despotović, Darko
AU  - Nenadović, Katarina
AU  - Sladojević, Željko
AU  - Dimitrijević, Sanda
AU  - Ilić, Tamara
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2524
AB  - This study is a retrospective analysis of social, economic, political, and cultural events on the annual incidence of trichinellosis in Bosnia and Herzegovina (BiH). It highlights the importance of specific regulations, which have been incorporated into developing preventive protection against this human disease for the last 61 years since it has been monitored by law. In the period, 1961–2021, 3828 people became infected. The first outbreak of trichinellosis was documented in 1965, and the incidence peaked during the war and post-war period at the end of the twentieth century. At that time, outbreaks with hundreds of cases and five deaths were recorded. In the first decade of the twenty-first century, the incidence decreased, and at the end of the second decade, two consecutive years without trichinellosis cases were finally registered. The analysis shows that a significantly higher incidence rate was recorded between the two political entities of BiH, the Republic of Srpska (4.97% 000) versus the Federation of BiH (0.9% 000) and that the occurrence of trichinellosis in humans in BiH is related to the presence of Trichinella spp. in animals, of a degree of biosecurity on pig farms, population’s awareness of safe food, the impact of tradition and religion on eating habits, doctors’ awareness of the symptomatology, and the Trichinella spp. larva detection method in muscle samples. The spread risk of trichinellosis requires meat inspection for Trichinella spp. larvae to be mandatory in BiH
PB  - Springer
T2  - Parasitology Research
T1  - Epidemiology and risk factors of trichinellosis in Bosnia and Herzegovina from 1961 to 2021
VL  - 122
IS  - 2
SP  - 635
EP  - 643
EP  - Ilić, Tamara
DO  - 10.1007/s00436-022-07767-2
ER  - 
@article{
author = "Despotović, Darko and Nenadović, Katarina and Sladojević, Željko and Dimitrijević, Sanda and Ilić, Tamara",
year = "2023",
abstract = "This study is a retrospective analysis of social, economic, political, and cultural events on the annual incidence of trichinellosis in Bosnia and Herzegovina (BiH). It highlights the importance of specific regulations, which have been incorporated into developing preventive protection against this human disease for the last 61 years since it has been monitored by law. In the period, 1961–2021, 3828 people became infected. The first outbreak of trichinellosis was documented in 1965, and the incidence peaked during the war and post-war period at the end of the twentieth century. At that time, outbreaks with hundreds of cases and five deaths were recorded. In the first decade of the twenty-first century, the incidence decreased, and at the end of the second decade, two consecutive years without trichinellosis cases were finally registered. The analysis shows that a significantly higher incidence rate was recorded between the two political entities of BiH, the Republic of Srpska (4.97% 000) versus the Federation of BiH (0.9% 000) and that the occurrence of trichinellosis in humans in BiH is related to the presence of Trichinella spp. in animals, of a degree of biosecurity on pig farms, population’s awareness of safe food, the impact of tradition and religion on eating habits, doctors’ awareness of the symptomatology, and the Trichinella spp. larva detection method in muscle samples. The spread risk of trichinellosis requires meat inspection for Trichinella spp. larvae to be mandatory in BiH",
publisher = "Springer",
journal = "Parasitology Research",
title = "Epidemiology and risk factors of trichinellosis in Bosnia and Herzegovina from 1961 to 2021",
volume = "122",
number = "2",
pages = "635-643-Ilić, Tamara",
doi = "10.1007/s00436-022-07767-2"
}
Despotović, D., Nenadović, K., Sladojević, Ž., Dimitrijević, S.,& Ilić, T.. (2023). Epidemiology and risk factors of trichinellosis in Bosnia and Herzegovina from 1961 to 2021. in Parasitology Research
Springer., 122(2), 635-643.
https://doi.org/10.1007/s00436-022-07767-2
Despotović D, Nenadović K, Sladojević Ž, Dimitrijević S, Ilić T. Epidemiology and risk factors of trichinellosis in Bosnia and Herzegovina from 1961 to 2021. in Parasitology Research. 2023;122(2):635-643.
doi:10.1007/s00436-022-07767-2 .
Despotović, Darko, Nenadović, Katarina, Sladojević, Željko, Dimitrijević, Sanda, Ilić, Tamara, "Epidemiology and risk factors of trichinellosis in Bosnia and Herzegovina from 1961 to 2021" in Parasitology Research, 122, no. 2 (2023):635-643,
https://doi.org/10.1007/s00436-022-07767-2 . .
2

The presence of malignant ovine babesiosis in Bosnia and Herzegovina indicates a possible emerging risk for Balkan region

Stevanović, Oliver; Radalj, Andrea; Subić, Ivona; Jovanović, Nemanja M.; Sladojević, Željko; Amović, Mladen; Zuko, Almedina; Nedić, Drago; Ilić, Tamara

(Elsevier, 2022)

TY  - JOUR
AU  - Stevanović, Oliver
AU  - Radalj, Andrea
AU  - Subić, Ivona
AU  - Jovanović, Nemanja M.
AU  - Sladojević, Željko
AU  - Amović, Mladen
AU  - Zuko, Almedina
AU  - Nedić, Drago
AU  - Ilić, Tamara
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2509
AB  - Malignant ovine babesiosis or ovine babesiosis caused by Babesia ovis is an important hemoprotozoan tick-borne disease of sheep. After 70 years, a study was conducted in Bosnia and Herzegovina, in the geographical areas of Podrinje and Eastern Herzegovina, aiming to molecularly identify and determine the presence of B. ovis infection in the sheep population. From 2019 to 2021, a clinical and molecular study was conducted in 53 flocks, and 192 sheep were examined, divided into two groups: clinically suspected and asymptomatic sheep. The presence of B. ovis was confirmed by PCR in blood samples of 75% and 11.21% of clinically affected and asymptomatic sheep, respectively. The majority of clinical cases of malignant ovine babesiosis were confirmed in the Rudo epidemiological unit (78.78%) within the Podrinje region indicating typical seasonal patern of disease occurence and endemic focus. Rhipicephalus bursa was only tick species identified in Podrinje and Eastern Herzegovina. Acute form of disease was observed with dominant clinical signs of depression, fever, loss of appetite and respiratory distress. Fatal outcome was recorded in 12.28% of cases. This study describes the molecular detection of B. ovis in sheep in Bosnia and Herzegovina for the first time. To the authors knowledge, this survey represents a report of the highest number of clinical cases of malignant ovine babesiosis in Europe. Since the disease has been recorded in the south-eastern border of Bosnia and Herzegovina, there is a high risk of disease transmission to a wider area of the Balkan region.
PB  - Elsevier
T2  - Comparative Immunology, Microbiology and Infectious Diseases
T1  - The presence of malignant ovine babesiosis in Bosnia and Herzegovina indicates a possible emerging risk for Balkan region
VL  - 90-91
SP  - 101893
DO  - 10.1016/j.cimid.2022.101893
ER  - 
@article{
author = "Stevanović, Oliver and Radalj, Andrea and Subić, Ivona and Jovanović, Nemanja M. and Sladojević, Željko and Amović, Mladen and Zuko, Almedina and Nedić, Drago and Ilić, Tamara",
year = "2022",
abstract = "Malignant ovine babesiosis or ovine babesiosis caused by Babesia ovis is an important hemoprotozoan tick-borne disease of sheep. After 70 years, a study was conducted in Bosnia and Herzegovina, in the geographical areas of Podrinje and Eastern Herzegovina, aiming to molecularly identify and determine the presence of B. ovis infection in the sheep population. From 2019 to 2021, a clinical and molecular study was conducted in 53 flocks, and 192 sheep were examined, divided into two groups: clinically suspected and asymptomatic sheep. The presence of B. ovis was confirmed by PCR in blood samples of 75% and 11.21% of clinically affected and asymptomatic sheep, respectively. The majority of clinical cases of malignant ovine babesiosis were confirmed in the Rudo epidemiological unit (78.78%) within the Podrinje region indicating typical seasonal patern of disease occurence and endemic focus. Rhipicephalus bursa was only tick species identified in Podrinje and Eastern Herzegovina. Acute form of disease was observed with dominant clinical signs of depression, fever, loss of appetite and respiratory distress. Fatal outcome was recorded in 12.28% of cases. This study describes the molecular detection of B. ovis in sheep in Bosnia and Herzegovina for the first time. To the authors knowledge, this survey represents a report of the highest number of clinical cases of malignant ovine babesiosis in Europe. Since the disease has been recorded in the south-eastern border of Bosnia and Herzegovina, there is a high risk of disease transmission to a wider area of the Balkan region.",
publisher = "Elsevier",
journal = "Comparative Immunology, Microbiology and Infectious Diseases",
title = "The presence of malignant ovine babesiosis in Bosnia and Herzegovina indicates a possible emerging risk for Balkan region",
volume = "90-91",
pages = "101893",
doi = "10.1016/j.cimid.2022.101893"
}
Stevanović, O., Radalj, A., Subić, I., Jovanović, N. M., Sladojević, Ž., Amović, M., Zuko, A., Nedić, D.,& Ilić, T.. (2022). The presence of malignant ovine babesiosis in Bosnia and Herzegovina indicates a possible emerging risk for Balkan region. in Comparative Immunology, Microbiology and Infectious Diseases
Elsevier., 90-91, 101893.
https://doi.org/10.1016/j.cimid.2022.101893
Stevanović O, Radalj A, Subić I, Jovanović NM, Sladojević Ž, Amović M, Zuko A, Nedić D, Ilić T. The presence of malignant ovine babesiosis in Bosnia and Herzegovina indicates a possible emerging risk for Balkan region. in Comparative Immunology, Microbiology and Infectious Diseases. 2022;90-91:101893.
doi:10.1016/j.cimid.2022.101893 .
Stevanović, Oliver, Radalj, Andrea, Subić, Ivona, Jovanović, Nemanja M., Sladojević, Željko, Amović, Mladen, Zuko, Almedina, Nedić, Drago, Ilić, Tamara, "The presence of malignant ovine babesiosis in Bosnia and Herzegovina indicates a possible emerging risk for Balkan region" in Comparative Immunology, Microbiology and Infectious Diseases, 90-91 (2022):101893,
https://doi.org/10.1016/j.cimid.2022.101893 . .
5

Kortizol mleka kao indikator stresa kod krava

Knežević, Dragan; Nedić, Sreten; Jovanović, Ljubomir; Bošnjaković, Dušan; Golić, Bojan; Kasagić, Dragan; Kirovski, Danijela; Sladojević, Željko

(2021)

TY  - CONF
AU  - Knežević, Dragan
AU  - Nedić, Sreten
AU  - Jovanović, Ljubomir
AU  - Bošnjaković, Dušan
AU  - Golić, Bojan
AU  - Kasagić, Dragan
AU  - Kirovski, Danijela
AU  - Sladojević, Željko
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2276
AB  - Кортизол је присутан у млеку крава и потиче из крви у којој његова
концентрација расте као одговор на акутни стрес. С обзиром да краве често не
показују јасне знаке стресног стања, значајно је утврдити дијагностичке
биомаркере који би указали да се јединка налази у стању стреса. Један од
најзначајнијих биомаркера стреса је концентрација кортизола у крви крава.
Међутим, узорковање крви изазива стрес, тако да би биомаркери добијени из
билошких течности које се узоркују без изазивања стреса били много вреднији
за дијагностику стресног стања. У том смислу узорак избора је млеко, јер се
његово узорковање врши без манипулације са животињом, односно у
потпуности је у складу са препорукама везаним за добробит животиња.
Концентрација кортизола у млеку је нижа него у крви и износи око 4 %
концентрације у крвној плазми с обзиром да само слободна форма хормона
прелази из крви у млеко и да ћелије млечне жлезде садрже високо афинитетне
рецепторе за овај хормон који га везују при његовом преласку из крви у млеко.
У млеку се налази везујући протеин за кортикостероиде који доспева из крви а
затим везује извесну количину кортизола млека. Његова заступљеност у млеку
је различита у различитим фазама лактације. Концентрација слободног
кортизола у млеку је у високој позитивној корелацији са концентрацијом слободног кортизола у крви док концентрација везаног кортизола млека не показује тако висок степен корелације са концентрацијом везаног кортизола у крви. Методологија одређивања концентрација како слобоног тако и везаног кортизола у млеку крава је успостављена и потврђена у нашим резултатима због чега је оправдано препоручити млеко као приоритетни биолошки
материјал за одређивање кортизола као биомаркера акутног стреса код крава.
Додатно, наши резултати указују да је након екстракције кортизола најбоље
применити RIA (eng. radioimmunoassay) методу с обзиром на ниске
концентрације кортизола у млеку током каснијих фаза лактације које
захтевају високу осетљивост методе да би били детектовани.
AB  - Cortisol is present in cows’ milk and originated from blood in which its
concentration increase due to acute stress. As cows do not always show clear signs
of dicomfort, reliable diagnostic biomarker could be used to provide information
regarding cows’ stress. One of the most relaible biomarker is blood cortisol
concentration. However, blood sampling usually provoke stress, and therefore
biomarkers that originated from biological fluids that might be sampling without
stress would be more valiable for stress diagnostic. Milk can be viewed as the
sampling site of first choice, since it could be measured without manipulation of
animals, hence it is completely compatible with animal welfare recomendations.
Milk cortisol concentration is lower than in blood and is 4% of blood
concentration since only free form transfer from blood to milk and mammary cells
have high-affinity receptors that binds hormone during its transfer from blood to
milk. There is corticoid binding protein in milk that originates from blood and that
bind some of cortisol in milk. Its abundance in milk is different in different stages
of lactation. Free milk cortisol concentration is highly positively correlated with
free blood cortisol concentration, while bound milk cortisol concentration is not
highly positively correlated with bound blood cortisol concentration.
Methodology of determination of both free and bound cortisol in cows’ milk is established and confirmed in our results and thus it is justified to recomend milk
and biological material of choice for deterining cortisol as acute stress biomarker
in cows. Additionally, our results indicate that it is best to use RIA
(radioimmunoassay) method, after extraction of cortisol, as low concentrations of
milk cortisol during later phases of lactation need high sensitive method in order
to be detected.
C3  - 26th Annual Counselling of Doctors of Veterinary Medicine of Republic of Srpska (Bosnia and Hercegovina)
T1  - Kortizol mleka kao indikator stresa kod krava
T1  - Milk cortisol as stress indicator in cows
SP  - 141
EP  - 144
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2276
ER  - 
@conference{
author = "Knežević, Dragan and Nedić, Sreten and Jovanović, Ljubomir and Bošnjaković, Dušan and Golić, Bojan and Kasagić, Dragan and Kirovski, Danijela and Sladojević, Željko",
year = "2021",
abstract = "Кортизол је присутан у млеку крава и потиче из крви у којој његова
концентрација расте као одговор на акутни стрес. С обзиром да краве често не
показују јасне знаке стресног стања, значајно је утврдити дијагностичке
биомаркере који би указали да се јединка налази у стању стреса. Један од
најзначајнијих биомаркера стреса је концентрација кортизола у крви крава.
Међутим, узорковање крви изазива стрес, тако да би биомаркери добијени из
билошких течности које се узоркују без изазивања стреса били много вреднији
за дијагностику стресног стања. У том смислу узорак избора је млеко, јер се
његово узорковање врши без манипулације са животињом, односно у
потпуности је у складу са препорукама везаним за добробит животиња.
Концентрација кортизола у млеку је нижа него у крви и износи око 4 %
концентрације у крвној плазми с обзиром да само слободна форма хормона
прелази из крви у млеко и да ћелије млечне жлезде садрже високо афинитетне
рецепторе за овај хормон који га везују при његовом преласку из крви у млеко.
У млеку се налази везујући протеин за кортикостероиде који доспева из крви а
затим везује извесну количину кортизола млека. Његова заступљеност у млеку
је различита у различитим фазама лактације. Концентрација слободног
кортизола у млеку је у високој позитивној корелацији са концентрацијом слободног кортизола у крви док концентрација везаног кортизола млека не показује тако висок степен корелације са концентрацијом везаног кортизола у крви. Методологија одређивања концентрација како слобоног тако и везаног кортизола у млеку крава је успостављена и потврђена у нашим резултатима због чега је оправдано препоручити млеко као приоритетни биолошки
материјал за одређивање кортизола као биомаркера акутног стреса код крава.
Додатно, наши резултати указују да је након екстракције кортизола најбоље
применити RIA (eng. radioimmunoassay) методу с обзиром на ниске
концентрације кортизола у млеку током каснијих фаза лактације које
захтевају високу осетљивост методе да би били детектовани., Cortisol is present in cows’ milk and originated from blood in which its
concentration increase due to acute stress. As cows do not always show clear signs
of dicomfort, reliable diagnostic biomarker could be used to provide information
regarding cows’ stress. One of the most relaible biomarker is blood cortisol
concentration. However, blood sampling usually provoke stress, and therefore
biomarkers that originated from biological fluids that might be sampling without
stress would be more valiable for stress diagnostic. Milk can be viewed as the
sampling site of first choice, since it could be measured without manipulation of
animals, hence it is completely compatible with animal welfare recomendations.
Milk cortisol concentration is lower than in blood and is 4% of blood
concentration since only free form transfer from blood to milk and mammary cells
have high-affinity receptors that binds hormone during its transfer from blood to
milk. There is corticoid binding protein in milk that originates from blood and that
bind some of cortisol in milk. Its abundance in milk is different in different stages
of lactation. Free milk cortisol concentration is highly positively correlated with
free blood cortisol concentration, while bound milk cortisol concentration is not
highly positively correlated with bound blood cortisol concentration.
Methodology of determination of both free and bound cortisol in cows’ milk is established and confirmed in our results and thus it is justified to recomend milk
and biological material of choice for deterining cortisol as acute stress biomarker
in cows. Additionally, our results indicate that it is best to use RIA
(radioimmunoassay) method, after extraction of cortisol, as low concentrations of
milk cortisol during later phases of lactation need high sensitive method in order
to be detected.",
journal = "26th Annual Counselling of Doctors of Veterinary Medicine of Republic of Srpska (Bosnia and Hercegovina)",
title = "Kortizol mleka kao indikator stresa kod krava, Milk cortisol as stress indicator in cows",
pages = "141-144",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2276"
}
Knežević, D., Nedić, S., Jovanović, L., Bošnjaković, D., Golić, B., Kasagić, D., Kirovski, D.,& Sladojević, Ž.. (2021). Kortizol mleka kao indikator stresa kod krava. in 26th Annual Counselling of Doctors of Veterinary Medicine of Republic of Srpska (Bosnia and Hercegovina), 141-144.
https://hdl.handle.net/21.15107/rcub_veterinar_2276
Knežević D, Nedić S, Jovanović L, Bošnjaković D, Golić B, Kasagić D, Kirovski D, Sladojević Ž. Kortizol mleka kao indikator stresa kod krava. in 26th Annual Counselling of Doctors of Veterinary Medicine of Republic of Srpska (Bosnia and Hercegovina). 2021;:141-144.
https://hdl.handle.net/21.15107/rcub_veterinar_2276 .
Knežević, Dragan, Nedić, Sreten, Jovanović, Ljubomir, Bošnjaković, Dušan, Golić, Bojan, Kasagić, Dragan, Kirovski, Danijela, Sladojević, Željko, "Kortizol mleka kao indikator stresa kod krava" in 26th Annual Counselling of Doctors of Veterinary Medicine of Republic of Srpska (Bosnia and Hercegovina) (2021):141-144,
https://hdl.handle.net/21.15107/rcub_veterinar_2276 .

Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile

Trifković, Julijana; Jovanović, Ljubomir; Bošnjaković, Dušan; Savić, Đorđe; Stefanović, Srđan; Krajišnik, Tatjana; Sladojević, Željko; Kirovski, Danijela

(Springer, 2021)

TY  - JOUR
AU  - Trifković, Julijana
AU  - Jovanović, Ljubomir
AU  - Bošnjaković, Dušan
AU  - Savić, Đorđe
AU  - Stefanović, Srđan
AU  - Krajišnik, Tatjana
AU  - Sladojević, Željko
AU  - Kirovski, Danijela
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2272
AB  - This study examines the effect of season-related heat stress in dams on mineral status, and hematological profile of their calves. Ten Holstein dams (LowT group) were exposed to the 49-day-long period of low air temperature (5.2 ± 0.5 °C) and ten dams (HighT group) were exposed to a 53-day-long high air temperature (27.4 ± 0.4 °C). The dams' blood samples were taken one hour after parturition, while colostrum was sampled at 2, 14, and 26 h after calving. Ca, P, Mg, Na, K, Fe, Zn, Mn, and Se concentrations were significantly lower while Cu and Co concentrations were significantly higher at least in two examined colostrum sampling points in HighT group. Calf`s blood samples were taken before 1st colostrum intake, and on days 1, 2, 3, and 7 postnatal. Ca, P, Na, K, Fe, Cu, Zn, Mn, Se, and Co were significantly lower while concentration of Mg was significantly higher in calves that originated from HighT group at least at two examined sampling points. Season affected dam's blood mineral status but the pattern was not always the same as in calves, since Na, K, Cu, and Co were significantly higher in HighT group. Calves that originated from HighT group had significantly lower hemoglobin, hematocrit, MCV, MCH, and MPV values, as well as neutrophils and monocyte counts, while platelets, eosinophils, basophils, and lymphocyte counts were significantly higher. Season-related heat stress leads to a reduction of the most minerals in both dams' colostrum and calves' blood and certain minerals' deficiencies are linked to impaired calves' hematological adaptation.
PB  - Springer
T2  - Biological Trace Element Research
T1  - Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile
SP  - 1
EP  - 13
DO  - 10.1007/s12011-021-02834-8
ER  - 
@article{
author = "Trifković, Julijana and Jovanović, Ljubomir and Bošnjaković, Dušan and Savić, Đorđe and Stefanović, Srđan and Krajišnik, Tatjana and Sladojević, Željko and Kirovski, Danijela",
year = "2021",
abstract = "This study examines the effect of season-related heat stress in dams on mineral status, and hematological profile of their calves. Ten Holstein dams (LowT group) were exposed to the 49-day-long period of low air temperature (5.2 ± 0.5 °C) and ten dams (HighT group) were exposed to a 53-day-long high air temperature (27.4 ± 0.4 °C). The dams' blood samples were taken one hour after parturition, while colostrum was sampled at 2, 14, and 26 h after calving. Ca, P, Mg, Na, K, Fe, Zn, Mn, and Se concentrations were significantly lower while Cu and Co concentrations were significantly higher at least in two examined colostrum sampling points in HighT group. Calf`s blood samples were taken before 1st colostrum intake, and on days 1, 2, 3, and 7 postnatal. Ca, P, Na, K, Fe, Cu, Zn, Mn, Se, and Co were significantly lower while concentration of Mg was significantly higher in calves that originated from HighT group at least at two examined sampling points. Season affected dam's blood mineral status but the pattern was not always the same as in calves, since Na, K, Cu, and Co were significantly higher in HighT group. Calves that originated from HighT group had significantly lower hemoglobin, hematocrit, MCV, MCH, and MPV values, as well as neutrophils and monocyte counts, while platelets, eosinophils, basophils, and lymphocyte counts were significantly higher. Season-related heat stress leads to a reduction of the most minerals in both dams' colostrum and calves' blood and certain minerals' deficiencies are linked to impaired calves' hematological adaptation.",
publisher = "Springer",
journal = "Biological Trace Element Research",
title = "Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile",
pages = "1-13",
doi = "10.1007/s12011-021-02834-8"
}
Trifković, J., Jovanović, L., Bošnjaković, D., Savić, Đ., Stefanović, S., Krajišnik, T., Sladojević, Ž.,& Kirovski, D.. (2021). Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile. in Biological Trace Element Research
Springer., 1-13.
https://doi.org/10.1007/s12011-021-02834-8
Trifković J, Jovanović L, Bošnjaković D, Savić Đ, Stefanović S, Krajišnik T, Sladojević Ž, Kirovski D. Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile. in Biological Trace Element Research. 2021;:1-13.
doi:10.1007/s12011-021-02834-8 .
Trifković, Julijana, Jovanović, Ljubomir, Bošnjaković, Dušan, Savić, Đorđe, Stefanović, Srđan, Krajišnik, Tatjana, Sladojević, Željko, Kirovski, Danijela, "Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile" in Biological Trace Element Research (2021):1-13,
https://doi.org/10.1007/s12011-021-02834-8 . .
1
1

Cow milk insulin like growth factor-1: risk or benefit for human health?

Kirovski, Danijela; Knežević, Dragan; Golić, Bojan; Kasagić, Dragan; Jovanović, Ljubomir; Bošnjaković, Dušan; Trifković, Julijana; Sladojević, Željko

(Faculty of Agriculture, Republic of Srpska, Bosnia, 2021)

TY  - CONF
AU  - Kirovski, Danijela
AU  - Knežević, Dragan
AU  - Golić, Bojan
AU  - Kasagić, Dragan
AU  - Jovanović, Ljubomir
AU  - Bošnjaković, Dušan
AU  - Trifković, Julijana
AU  - Sladojević, Željko
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2274
AB  - Cow milk is widely consumed by human children and adults due to its nutritional value. Besides
nutrients, milk contains naturally occurring hormones, including insulin like growth factor-1
(IGF-1), that may alter their blood levels in the consumers. At the same time, the impact of IGF1 on human health is still unclear and controversial. The aim of the study was to determine IGF-1
concentrations in cow colostrum and milk and to discuss them from the aspect of human health.
Twenty Holstein cows were enrolled in the study and subjected to colostrum, milk and venous
blood sampling in order to determine the IGF-1 concentration by the radioimmunoassay (RIA).
Colostrum was sampled at 2, 14 and 26 hours (1st, 2nd and 3rd colostrum) after calving, while
milk and venous blood were taken 10 days after calving. The concentration of IGF-1 was the
highest in the 1
st colostrum and decreased significantly with each subsequent sampling, so the
lowest concentrations were detected in milk sampled 10 days after calving. High concentrations
of IGF-1 observed in colostrum, especially in the 1st colostrum, reflect its potential for eventually
use in the treatment of various intestinal diseases. However, further research should determine
the conditions and limitations of its application. On the other hand, additional research is needed
to determine whether IGF-1 in milk has harmful effects on human health and whether it is
necessary to limit the permitted presence of this hormone in cow milk.
PB  - Faculty of Agriculture, Republic of Srpska, Bosnia
C3  - Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“
T1  - Cow milk insulin like growth factor-1: risk or benefit for human health?
SP  - 1196
EP  - 1203
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2274
ER  - 
@conference{
author = "Kirovski, Danijela and Knežević, Dragan and Golić, Bojan and Kasagić, Dragan and Jovanović, Ljubomir and Bošnjaković, Dušan and Trifković, Julijana and Sladojević, Željko",
year = "2021",
abstract = "Cow milk is widely consumed by human children and adults due to its nutritional value. Besides
nutrients, milk contains naturally occurring hormones, including insulin like growth factor-1
(IGF-1), that may alter their blood levels in the consumers. At the same time, the impact of IGF1 on human health is still unclear and controversial. The aim of the study was to determine IGF-1
concentrations in cow colostrum and milk and to discuss them from the aspect of human health.
Twenty Holstein cows were enrolled in the study and subjected to colostrum, milk and venous
blood sampling in order to determine the IGF-1 concentration by the radioimmunoassay (RIA).
Colostrum was sampled at 2, 14 and 26 hours (1st, 2nd and 3rd colostrum) after calving, while
milk and venous blood were taken 10 days after calving. The concentration of IGF-1 was the
highest in the 1
st colostrum and decreased significantly with each subsequent sampling, so the
lowest concentrations were detected in milk sampled 10 days after calving. High concentrations
of IGF-1 observed in colostrum, especially in the 1st colostrum, reflect its potential for eventually
use in the treatment of various intestinal diseases. However, further research should determine
the conditions and limitations of its application. On the other hand, additional research is needed
to determine whether IGF-1 in milk has harmful effects on human health and whether it is
necessary to limit the permitted presence of this hormone in cow milk.",
publisher = "Faculty of Agriculture, Republic of Srpska, Bosnia",
journal = "Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“",
title = "Cow milk insulin like growth factor-1: risk or benefit for human health?",
pages = "1196-1203",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2274"
}
Kirovski, D., Knežević, D., Golić, B., Kasagić, D., Jovanović, L., Bošnjaković, D., Trifković, J.,& Sladojević, Ž.. (2021). Cow milk insulin like growth factor-1: risk or benefit for human health?. in Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“
Faculty of Agriculture, Republic of Srpska, Bosnia., 1196-1203.
https://hdl.handle.net/21.15107/rcub_veterinar_2274
Kirovski D, Knežević D, Golić B, Kasagić D, Jovanović L, Bošnjaković D, Trifković J, Sladojević Ž. Cow milk insulin like growth factor-1: risk or benefit for human health?. in Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“. 2021;:1196-1203.
https://hdl.handle.net/21.15107/rcub_veterinar_2274 .
Kirovski, Danijela, Knežević, Dragan, Golić, Bojan, Kasagić, Dragan, Jovanović, Ljubomir, Bošnjaković, Dušan, Trifković, Julijana, Sladojević, Željko, "Cow milk insulin like growth factor-1: risk or benefit for human health?" in Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“ (2021):1196-1203,
https://hdl.handle.net/21.15107/rcub_veterinar_2274 .

Estrogeni u konzumnom mleku dobijenom od gravidnih krava – potencijalni rizik po zdravlje ljudi?

Sladojević, Željko; Knežević, Dragan; Bošnjaković, Dušan; Jovanović, Ljubomir; Stojić, Milica; Dražić, Slavica; Kirovski, Danijela

(Fakultet veterinarske medicine, Beograd, 2021)

TY  - CONF
AU  - Sladojević, Željko
AU  - Knežević, Dragan
AU  - Bošnjaković, Dušan
AU  - Jovanović, Ljubomir
AU  - Stojić, Milica
AU  - Dražić, Slavica
AU  - Kirovski, Danijela
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2279
AB  - Mleko krava predstavlja veoma zastupljenu namirnicu u ishrani ljudi. Među­
tim, osim hranljivih materija, mleko sadrži i hormone, poput estrogena, zbog kojih
je konzumacija mleka prepoznata kao potencijalni rizik za zdravlje ljudi. Naime,
bovini i humani estrogeni imaju sličnu strukturu, te se smatra da unos estrogena
putem mleka krava može povećati nivo estrogena u krvi ljudi koji ga konzumira­
ju. Dodatno, mnoge studije dovode u vezu porast nivoa estrogena u cirkulaciji sa
pojavom hormonski zavisnih tumora u populaciji ljudi, uključujući karcinom dojke,
materice, jajnika, testisa i prostate. Cilj ovog rada je da, na se osnovu raspoloživih
podatka iz literature, analizira da li i u kojoj količini estrogeni mleka mogu biti rizik
po zdravlje ljudi, za koju uzrasnu kategoriju, kao i da li se pravilnim odabirom kra­
va koje se koriste za proizvodnju mleka može uticati na nivo estrogena u mleku
koje se koristi u ishrani konzumenata.
AB  - Cow’s milk is a very common food in the human diet. In addition to nutrients,
cow’s milk also contains hormones, such as estrogens, due to which the con­
sumption of milk is recognized as a potential risk to human health. Namely, bovi­
ne and human estrogens have a similar structure, and it has been hypothesized
that the intake of estrogens from cow’s milk can increase the level of estrogens
in consumers’ blood. Furthermore, many studies have examined the associations between circulating estrogens levels and the risk of hormone­sensitive tumors in
humans, including breast, uterine, ovarian, testicular, and prostate cancers. The
aim of this study is to examine, based on available literature data, if the estrogens
are potential risk for human health, in which concentrations, for which age group
and is it possible, by choosing adequate cows, to affect estrogen levels in cow’s
milk that is used by consumers.
PB  - Fakultet veterinarske medicine, Beograd
C3  - 12. naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 7 - 10. oktobar 2021
T1  - Estrogeni u konzumnom mleku dobijenom od gravidnih krava – potencijalni rizik po zdravlje ljudi?
T1  - Estrogens in pregnant cows milk – a potential risk for human health
SP  - 83
EP  - 90
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2279
ER  - 
@conference{
author = "Sladojević, Željko and Knežević, Dragan and Bošnjaković, Dušan and Jovanović, Ljubomir and Stojić, Milica and Dražić, Slavica and Kirovski, Danijela",
year = "2021",
abstract = "Mleko krava predstavlja veoma zastupljenu namirnicu u ishrani ljudi. Među­
tim, osim hranljivih materija, mleko sadrži i hormone, poput estrogena, zbog kojih
je konzumacija mleka prepoznata kao potencijalni rizik za zdravlje ljudi. Naime,
bovini i humani estrogeni imaju sličnu strukturu, te se smatra da unos estrogena
putem mleka krava može povećati nivo estrogena u krvi ljudi koji ga konzumira­
ju. Dodatno, mnoge studije dovode u vezu porast nivoa estrogena u cirkulaciji sa
pojavom hormonski zavisnih tumora u populaciji ljudi, uključujući karcinom dojke,
materice, jajnika, testisa i prostate. Cilj ovog rada je da, na se osnovu raspoloživih
podatka iz literature, analizira da li i u kojoj količini estrogeni mleka mogu biti rizik
po zdravlje ljudi, za koju uzrasnu kategoriju, kao i da li se pravilnim odabirom kra­
va koje se koriste za proizvodnju mleka može uticati na nivo estrogena u mleku
koje se koristi u ishrani konzumenata., Cow’s milk is a very common food in the human diet. In addition to nutrients,
cow’s milk also contains hormones, such as estrogens, due to which the con­
sumption of milk is recognized as a potential risk to human health. Namely, bovi­
ne and human estrogens have a similar structure, and it has been hypothesized
that the intake of estrogens from cow’s milk can increase the level of estrogens
in consumers’ blood. Furthermore, many studies have examined the associations between circulating estrogens levels and the risk of hormone­sensitive tumors in
humans, including breast, uterine, ovarian, testicular, and prostate cancers. The
aim of this study is to examine, based on available literature data, if the estrogens
are potential risk for human health, in which concentrations, for which age group
and is it possible, by choosing adequate cows, to affect estrogen levels in cow’s
milk that is used by consumers.",
publisher = "Fakultet veterinarske medicine, Beograd",
journal = "12. naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 7 - 10. oktobar 2021",
title = "Estrogeni u konzumnom mleku dobijenom od gravidnih krava – potencijalni rizik po zdravlje ljudi?, Estrogens in pregnant cows milk – a potential risk for human health",
pages = "83-90",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2279"
}
Sladojević, Ž., Knežević, D., Bošnjaković, D., Jovanović, L., Stojić, M., Dražić, S.,& Kirovski, D.. (2021). Estrogeni u konzumnom mleku dobijenom od gravidnih krava – potencijalni rizik po zdravlje ljudi?. in 12. naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 7 - 10. oktobar 2021
Fakultet veterinarske medicine, Beograd., 83-90.
https://hdl.handle.net/21.15107/rcub_veterinar_2279
Sladojević Ž, Knežević D, Bošnjaković D, Jovanović L, Stojić M, Dražić S, Kirovski D. Estrogeni u konzumnom mleku dobijenom od gravidnih krava – potencijalni rizik po zdravlje ljudi?. in 12. naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 7 - 10. oktobar 2021. 2021;:83-90.
https://hdl.handle.net/21.15107/rcub_veterinar_2279 .
Sladojević, Željko, Knežević, Dragan, Bošnjaković, Dušan, Jovanović, Ljubomir, Stojić, Milica, Dražić, Slavica, Kirovski, Danijela, "Estrogeni u konzumnom mleku dobijenom od gravidnih krava – potencijalni rizik po zdravlje ljudi?" in 12. naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 7 - 10. oktobar 2021 (2021):83-90,
https://hdl.handle.net/21.15107/rcub_veterinar_2279 .

Težak oblik generalizovane sarkoptes šuge sa sekundarnim piotraumatskim folikulitisom kod psa: epizootiološki i diferencijalno dijagnostički pristup

Stevanović, Oliver; Vujanić, Dejan; Dobrijević, Miljan; Trbojević, Igor; Sladojević, Željko; Laušević, Dejan; Nedić, Drago

(Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“, 2020)

TY  - JOUR
AU  - Stevanović, Oliver
AU  - Vujanić, Dejan
AU  - Dobrijević, Miljan
AU  - Trbojević, Igor
AU  - Sladojević, Željko
AU  - Laušević, Dejan
AU  - Nedić, Drago
PY  - 2020
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2195
AB  - U ovom radu je opisan slučaj generalizovane sarkoptes šuge
(sarkoptoze) kod psa lutalice koji je pronađen na području opštine Kotor Varoš.
Kliničkim i dermatološkim pregledom postavljena je sumnja na sarkoptes šugu kod
psa, što je potvrđeno nalazom jaja i adultnih oblika šugarca Sarcoptes scabiei var.
canis. Kao sekundarna komplikacija šuge, utvrđeno je prisustvo stafilokoknog
piotraumatskog folikulitisa. Hematološkim pregledom ustanovljena je anemija i
leukocitoza. U osnovnoj terapiji je korišćen ivermektin (parenteralno) u dozi 0,4
mg/kg sa cefaleksinom koji je aplikovan peroralno u dozi 40 mg/kg svakih 12 sati.
Terapija je trajala ukupno 30 dana. Kontrolnim pregledima nisu ustanovljeni
parazitski elementi u površinski ostruganoj koži. U diskusiji ovog rada su
prikazane epizootiološke karakteristike bolesti i navedene bolesti kože kod
pasa, koje se mogu pomiješati sa šugom u svakodnevnoj praksi.
AB  - This paper describes a case of generalized sarcoptic mange (Sarcoptes scabiei) in a stray
dog found in the Kotor Varoš Municipality. Clinical and dermatological examinations
revealed the suspicion of Sarcoptic mange in the dog, which was confirmed by the finding
of eggs and adult forms of Sarcoptes scabiei var. canis. As a secondary complication of
mange, the presence of staphylococcal pyotraumatic folliculitis was determined.
Hematological examination revealed anemia and leukocytosis. In basic therapy, 0.4 mg/kg
of ivermectin was administered parenterally, with cephalexin administered orally at a dose
of 40 mg/kg every 12 hours. The therapy lasted 30 days. Control examinations did not
reveal parasitic elements in the scraped surface layer of the skin. In the discussion of this
paper, the epizootiological characteristics of the disease and the list of dog`s skin diseases,
that should be distinguished from sarcoptic mange in everyday practice, are presented.
PB  - Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“
T2  - Veterinarski žurnal Republike Srpske
T1  - Težak oblik generalizovane sarkoptes šuge sa sekundarnim piotraumatskim folikulitisom kod psa: epizootiološki i diferencijalno dijagnostički pristup
T1  - Severe form of generalized sarcoptic mange with secondary piotraumatic folliculitis in dogs: Differential diagnosis and epizootiological approach
VL  - 20
IS  - 1-2
SP  - 141
EP  - 162
DO  - 10.7251/VETJSR2001141S
ER  - 
@article{
author = "Stevanović, Oliver and Vujanić, Dejan and Dobrijević, Miljan and Trbojević, Igor and Sladojević, Željko and Laušević, Dejan and Nedić, Drago",
year = "2020",
abstract = "U ovom radu je opisan slučaj generalizovane sarkoptes šuge
(sarkoptoze) kod psa lutalice koji je pronađen na području opštine Kotor Varoš.
Kliničkim i dermatološkim pregledom postavljena je sumnja na sarkoptes šugu kod
psa, što je potvrđeno nalazom jaja i adultnih oblika šugarca Sarcoptes scabiei var.
canis. Kao sekundarna komplikacija šuge, utvrđeno je prisustvo stafilokoknog
piotraumatskog folikulitisa. Hematološkim pregledom ustanovljena je anemija i
leukocitoza. U osnovnoj terapiji je korišćen ivermektin (parenteralno) u dozi 0,4
mg/kg sa cefaleksinom koji je aplikovan peroralno u dozi 40 mg/kg svakih 12 sati.
Terapija je trajala ukupno 30 dana. Kontrolnim pregledima nisu ustanovljeni
parazitski elementi u površinski ostruganoj koži. U diskusiji ovog rada su
prikazane epizootiološke karakteristike bolesti i navedene bolesti kože kod
pasa, koje se mogu pomiješati sa šugom u svakodnevnoj praksi., This paper describes a case of generalized sarcoptic mange (Sarcoptes scabiei) in a stray
dog found in the Kotor Varoš Municipality. Clinical and dermatological examinations
revealed the suspicion of Sarcoptic mange in the dog, which was confirmed by the finding
of eggs and adult forms of Sarcoptes scabiei var. canis. As a secondary complication of
mange, the presence of staphylococcal pyotraumatic folliculitis was determined.
Hematological examination revealed anemia and leukocytosis. In basic therapy, 0.4 mg/kg
of ivermectin was administered parenterally, with cephalexin administered orally at a dose
of 40 mg/kg every 12 hours. The therapy lasted 30 days. Control examinations did not
reveal parasitic elements in the scraped surface layer of the skin. In the discussion of this
paper, the epizootiological characteristics of the disease and the list of dog`s skin diseases,
that should be distinguished from sarcoptic mange in everyday practice, are presented.",
publisher = "Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“",
journal = "Veterinarski žurnal Republike Srpske",
title = "Težak oblik generalizovane sarkoptes šuge sa sekundarnim piotraumatskim folikulitisom kod psa: epizootiološki i diferencijalno dijagnostički pristup, Severe form of generalized sarcoptic mange with secondary piotraumatic folliculitis in dogs: Differential diagnosis and epizootiological approach",
volume = "20",
number = "1-2",
pages = "141-162",
doi = "10.7251/VETJSR2001141S"
}
Stevanović, O., Vujanić, D., Dobrijević, M., Trbojević, I., Sladojević, Ž., Laušević, D.,& Nedić, D.. (2020). Težak oblik generalizovane sarkoptes šuge sa sekundarnim piotraumatskim folikulitisom kod psa: epizootiološki i diferencijalno dijagnostički pristup. in Veterinarski žurnal Republike Srpske
Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“., 20(1-2), 141-162.
https://doi.org/10.7251/VETJSR2001141S
Stevanović O, Vujanić D, Dobrijević M, Trbojević I, Sladojević Ž, Laušević D, Nedić D. Težak oblik generalizovane sarkoptes šuge sa sekundarnim piotraumatskim folikulitisom kod psa: epizootiološki i diferencijalno dijagnostički pristup. in Veterinarski žurnal Republike Srpske. 2020;20(1-2):141-162.
doi:10.7251/VETJSR2001141S .
Stevanović, Oliver, Vujanić, Dejan, Dobrijević, Miljan, Trbojević, Igor, Sladojević, Željko, Laušević, Dejan, Nedić, Drago, "Težak oblik generalizovane sarkoptes šuge sa sekundarnim piotraumatskim folikulitisom kod psa: epizootiološki i diferencijalno dijagnostički pristup" in Veterinarski žurnal Republike Srpske, 20, no. 1-2 (2020):141-162,
https://doi.org/10.7251/VETJSR2001141S . .

Influence of different seasons during late gestation on Holstein cows colostrum and postnatal adaptive capability of their calves

Trifković, Julijana; Jovanović, Ljubomir; Đurić, Miloje; Stevanovic-Đorđević, Snežana; Milanović, Svetlana; Lazarević, Miodrag; Sladojević, Željko; Kirovski, Danijela

(Springer, New York, 2018)

TY  - JOUR
AU  - Trifković, Julijana
AU  - Jovanović, Ljubomir
AU  - Đurić, Miloje
AU  - Stevanovic-Đorđević, Snežana
AU  - Milanović, Svetlana
AU  - Lazarević, Miodrag
AU  - Sladojević, Željko
AU  - Kirovski, Danijela
PY  - 2018
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1669
AB  - Season may affect calves thermal comfort and behavior, but the data related to the overall influence of seasonal variations on dams colostrum and postnatal adaptive capability of calves are limited. The aim of this study was to measure the effects of a 49-day-long low air temperature (LAT) season (5.20 +/- 0.46 A degrees C mean air temperature) and a 53-day-long high air temperature (HAT) season (27.40 +/- 0.39 A degrees C mean air temperature) on dams colostrum quality and physiological, biochemical, hormonal, and oxidative stress parameters of their calves during the first 7 days of life. The dams colostrum was sampled at 2, 14, and 26 h after calving, before feeding of their calves. Calves blood samples were taken before the first colostrum intake and on days 1, 2, 3, and 7 of life. Calves physiological parameters were measured on days 0 and 7. HAT season significantly reduced the quality of dams colostrum. The ingestion of the low-quality colostrum, combined with the thermal discomfort during HAT season, probably provoked impaired physiological, biochemical, hormonal, and oxidative stress parameters in samples taken from the post-colostral calves. Additionally, intravenous glucose tolerance test was performed on day 7, which suggested an enhanced insulin response in HAT season calves. This study highlights the importance of adequate supporting strategies for the care of the late gestation cows and postnatal calves during the HAT season.
PB  - Springer, New York
T2  - International Journal of Biometeorology
T1  - Influence of different seasons during late gestation on Holstein cows  colostrum and postnatal adaptive capability of their calves
VL  - 62
IS  - 6
SP  - 1097
EP  - 1108
DO  - 10.1007/s00484-018-1514-6
ER  - 
@article{
author = "Trifković, Julijana and Jovanović, Ljubomir and Đurić, Miloje and Stevanovic-Đorđević, Snežana and Milanović, Svetlana and Lazarević, Miodrag and Sladojević, Željko and Kirovski, Danijela",
year = "2018",
abstract = "Season may affect calves thermal comfort and behavior, but the data related to the overall influence of seasonal variations on dams colostrum and postnatal adaptive capability of calves are limited. The aim of this study was to measure the effects of a 49-day-long low air temperature (LAT) season (5.20 +/- 0.46 A degrees C mean air temperature) and a 53-day-long high air temperature (HAT) season (27.40 +/- 0.39 A degrees C mean air temperature) on dams colostrum quality and physiological, biochemical, hormonal, and oxidative stress parameters of their calves during the first 7 days of life. The dams colostrum was sampled at 2, 14, and 26 h after calving, before feeding of their calves. Calves blood samples were taken before the first colostrum intake and on days 1, 2, 3, and 7 of life. Calves physiological parameters were measured on days 0 and 7. HAT season significantly reduced the quality of dams colostrum. The ingestion of the low-quality colostrum, combined with the thermal discomfort during HAT season, probably provoked impaired physiological, biochemical, hormonal, and oxidative stress parameters in samples taken from the post-colostral calves. Additionally, intravenous glucose tolerance test was performed on day 7, which suggested an enhanced insulin response in HAT season calves. This study highlights the importance of adequate supporting strategies for the care of the late gestation cows and postnatal calves during the HAT season.",
publisher = "Springer, New York",
journal = "International Journal of Biometeorology",
title = "Influence of different seasons during late gestation on Holstein cows  colostrum and postnatal adaptive capability of their calves",
volume = "62",
number = "6",
pages = "1097-1108",
doi = "10.1007/s00484-018-1514-6"
}
Trifković, J., Jovanović, L., Đurić, M., Stevanovic-Đorđević, S., Milanović, S., Lazarević, M., Sladojević, Ž.,& Kirovski, D.. (2018). Influence of different seasons during late gestation on Holstein cows  colostrum and postnatal adaptive capability of their calves. in International Journal of Biometeorology
Springer, New York., 62(6), 1097-1108.
https://doi.org/10.1007/s00484-018-1514-6
Trifković J, Jovanović L, Đurić M, Stevanovic-Đorđević S, Milanović S, Lazarević M, Sladojević Ž, Kirovski D. Influence of different seasons during late gestation on Holstein cows  colostrum and postnatal adaptive capability of their calves. in International Journal of Biometeorology. 2018;62(6):1097-1108.
doi:10.1007/s00484-018-1514-6 .
Trifković, Julijana, Jovanović, Ljubomir, Đurić, Miloje, Stevanovic-Đorđević, Snežana, Milanović, Svetlana, Lazarević, Miodrag, Sladojević, Željko, Kirovski, Danijela, "Influence of different seasons during late gestation on Holstein cows  colostrum and postnatal adaptive capability of their calves" in International Journal of Biometeorology, 62, no. 6 (2018):1097-1108,
https://doi.org/10.1007/s00484-018-1514-6 . .
5
5
6

Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves

Kirovski, Danijela; Dodovski, Petar; Savić, Đorđe; Vujanac, Ivan; Prodanović, Radiša; Mirilović, Milorad; Sladojević, Željko; Đorđević, Ana

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2016)

TY  - JOUR
AU  - Kirovski, Danijela
AU  - Dodovski, Petar
AU  - Savić, Đorđe
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Mirilović, Milorad
AU  - Sladojević, Željko
AU  - Đorđević, Ana
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1366
AB  - The aim of our study was to investigate if the thyroid axis of newborn calves is affected by prenatal application of propylthyouracil (PTU). The study included 20 late pregnant Holstein cows. One group (n=10) was treated with PTU (4 mg/kg of BW daily) from day 20 before expected calving until the day of calving. The other group (n=10) was non-treated. Placental samples of dams were obtained for measuring mRNA expression of iodothyronine deiodinases type I (D1), type II (D2) and type III (D3). After parturition calves were separated from the dams and included in the study. Blood samples were taken daily from each calf starting on the day of birth until day 7 of age. Blood T3, T4 and TSH concentrations were measured. PCR analysis of the placental tissue revealed an abundance of all three types of placental deiodinases in non-treated cows, and a significant elevation of mRNA levels for all three types of deiodinases after PTU treatment. Calves that originated from dams treated with PTU had significantly lower T3 and T4 and significantly higher TSH concentrations compared to non-treated calves during the first 2 days of life. Starting from day 4 until day 6 of life the opposite effect was observed meaning that calves prenatally exposed to PTU had significantly higher T3 and T4 and slightly lower TSH. Our study, for the first time, provides information related to iodothyronine deiodinases mRNA expression in bovine placenta, and confirm that PTU treatment of pregnant dams provokes depression of thyroid function in newborns during the first days of life.
AB  - Cilj ovog rada bio je da se ispita da li je tireoidna osovina novorođene teladi promenjena nakon prenatalne aplikacije propiltiouracila (PTU). U ogled je uključeno 20 krava holštajn rase u kasnom graviditetu. Prva grupa (n=10) je tretirana PTU (4 mg/kg telesne mase, dnevna doza) počevši od 20 dana pre očekivanog teljenja do dana teljenja. Druga grupa (n=10) nije tretirana. Uzorci placente krava uzimani su u cilju određivanja ekspresije iRNK dejodinaza tipa I (D1), tipa II (D2) i tipa III (D3). Nakon teljenja, telad su odvojena od majki i uključena u ispitivanja. Uzorci krvi su uzimani dnevno od svakog teleta počevši od dana rođenja do 7. dana života. U krvi su merene koncentracije T3, T4 i TSH. PCR analiza tkiva placente je pokazala zastupljenost sva tri tipa dejodinaza kod netretiranih krava, i značajno povećanje nivoa iRNK sva tri tipa dejodinaza nakon tretmana PTU. Telad koja su poticala od majki tretiranih PTU imala su značajno niže koncentracije T3 i T4 i značajno više koncentracije TSH u odnosu na telad poreklom od netretiranih majki, tokom prva dva dana života. U periodu od 4. do 6. dana života, utvrđen je suprotan efekat, što znači da su telad prenatalno izložena delovanju PTU imala značajno više koncentracije T3 i T4 i značajno niže koncentracije TSH u odnosu na netretiranu telad. Naša studija, po prvi put, daje informacije vezane za ekspresiju dejodinaza u bovinoj placenti i potvrđuje da tretman gravidnih majki sa PTU izaziva depresiju funkcije tireoidne osovine kod novorođenčadi tokom prva dva dana neonatalnog života.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves
T1  - Ekspresija dejodinaza u placenti krava tretiranih sa propiltiouracilom (PTU) i aktivnost tireoidne osovine njihove teladi
VL  - 66
IS  - 1
SP  - 61
EP  - 75
DO  - 10.1515/acve-2016-0005
ER  - 
@article{
author = "Kirovski, Danijela and Dodovski, Petar and Savić, Đorđe and Vujanac, Ivan and Prodanović, Radiša and Mirilović, Milorad and Sladojević, Željko and Đorđević, Ana",
year = "2016",
abstract = "The aim of our study was to investigate if the thyroid axis of newborn calves is affected by prenatal application of propylthyouracil (PTU). The study included 20 late pregnant Holstein cows. One group (n=10) was treated with PTU (4 mg/kg of BW daily) from day 20 before expected calving until the day of calving. The other group (n=10) was non-treated. Placental samples of dams were obtained for measuring mRNA expression of iodothyronine deiodinases type I (D1), type II (D2) and type III (D3). After parturition calves were separated from the dams and included in the study. Blood samples were taken daily from each calf starting on the day of birth until day 7 of age. Blood T3, T4 and TSH concentrations were measured. PCR analysis of the placental tissue revealed an abundance of all three types of placental deiodinases in non-treated cows, and a significant elevation of mRNA levels for all three types of deiodinases after PTU treatment. Calves that originated from dams treated with PTU had significantly lower T3 and T4 and significantly higher TSH concentrations compared to non-treated calves during the first 2 days of life. Starting from day 4 until day 6 of life the opposite effect was observed meaning that calves prenatally exposed to PTU had significantly higher T3 and T4 and slightly lower TSH. Our study, for the first time, provides information related to iodothyronine deiodinases mRNA expression in bovine placenta, and confirm that PTU treatment of pregnant dams provokes depression of thyroid function in newborns during the first days of life., Cilj ovog rada bio je da se ispita da li je tireoidna osovina novorođene teladi promenjena nakon prenatalne aplikacije propiltiouracila (PTU). U ogled je uključeno 20 krava holštajn rase u kasnom graviditetu. Prva grupa (n=10) je tretirana PTU (4 mg/kg telesne mase, dnevna doza) počevši od 20 dana pre očekivanog teljenja do dana teljenja. Druga grupa (n=10) nije tretirana. Uzorci placente krava uzimani su u cilju određivanja ekspresije iRNK dejodinaza tipa I (D1), tipa II (D2) i tipa III (D3). Nakon teljenja, telad su odvojena od majki i uključena u ispitivanja. Uzorci krvi su uzimani dnevno od svakog teleta počevši od dana rođenja do 7. dana života. U krvi su merene koncentracije T3, T4 i TSH. PCR analiza tkiva placente je pokazala zastupljenost sva tri tipa dejodinaza kod netretiranih krava, i značajno povećanje nivoa iRNK sva tri tipa dejodinaza nakon tretmana PTU. Telad koja su poticala od majki tretiranih PTU imala su značajno niže koncentracije T3 i T4 i značajno više koncentracije TSH u odnosu na telad poreklom od netretiranih majki, tokom prva dva dana života. U periodu od 4. do 6. dana života, utvrđen je suprotan efekat, što znači da su telad prenatalno izložena delovanju PTU imala značajno više koncentracije T3 i T4 i značajno niže koncentracije TSH u odnosu na netretiranu telad. Naša studija, po prvi put, daje informacije vezane za ekspresiju dejodinaza u bovinoj placenti i potvrđuje da tretman gravidnih majki sa PTU izaziva depresiju funkcije tireoidne osovine kod novorođenčadi tokom prva dva dana neonatalnog života.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves, Ekspresija dejodinaza u placenti krava tretiranih sa propiltiouracilom (PTU) i aktivnost tireoidne osovine njihove teladi",
volume = "66",
number = "1",
pages = "61-75",
doi = "10.1515/acve-2016-0005"
}
Kirovski, D., Dodovski, P., Savić, Đ., Vujanac, I., Prodanović, R., Mirilović, M., Sladojević, Ž.,& Đorđević, A.. (2016). Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 66(1), 61-75.
https://doi.org/10.1515/acve-2016-0005
Kirovski D, Dodovski P, Savić Đ, Vujanac I, Prodanović R, Mirilović M, Sladojević Ž, Đorđević A. Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves. in Acta Veterinaria-Beograd. 2016;66(1):61-75.
doi:10.1515/acve-2016-0005 .
Kirovski, Danijela, Dodovski, Petar, Savić, Đorđe, Vujanac, Ivan, Prodanović, Radiša, Mirilović, Milorad, Sladojević, Željko, Đorđević, Ana, "Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves" in Acta Veterinaria-Beograd, 66, no. 1 (2016):61-75,
https://doi.org/10.1515/acve-2016-0005 . .
4
3
4

Effects of Bentonite on Weight Gain, Feed Consumption, Blood Metabolites and Ruminal Protozoa in Dairy Calves

Kirovski, Danijela; Adamović, M.; Radivojević, Mihajlo; Šamanc, Horea; Vujanac, Ivan; Prodanović, Radiša; Sladojević, Željko

(Animal Nutrition Assoc, Izatnagar, 2015)

TY  - JOUR
AU  - Kirovski, Danijela
AU  - Adamović, M.
AU  - Radivojević, Mihajlo
AU  - Šamanc, Horea
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Sladojević, Željko
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1185
AB  - In order to ascertain the effects of addition of bentonite as a pelleting medium in the feed mixture for calves, fourteen 30d-old calves were randomly distributed into two equal groups (CON and EXP). From 30 to 120d of age the EXP group was fed a feed mixture containing 1.5% of natural bentonite while the CON group was fed the same pellets without added bentonite. Body weight was determined before and at the end of the trial. Feed intake was measured daily. Health status was monitored daily. Blood and rumen content samples were taken at 50 and 90d of experiment and analyzed for select parameters. The addition of bentonite had no effect (P > 0.05) on average daily gain, feed intake and health. Blood pH, total number and motility of ruminal protozoa in the EXP group were significantly (P < 0.001, P < 0.05 and P < 0.05; respectively) higher than in CON group at both the periods. At 120d of age the EXP calves had a significantly (P < 0.05, P < 0.05 and P < 0.01; respectively) higher serum total protein, albumin and triglyceride concentrations and lower iron and IGF-I (P < 0.05 and P < 0.01, respectively) concentrations than respective controls values. It is concluded that the use of pelleted feed containing bentonite tended to improve growth of calves as well as the activity of protozoa in the rumen. Additionally, the results indicate a positive influence of the function of hepatocytes concomitant to a reduction in serum iron and IGF-I concentrations.
PB  - Animal Nutrition Assoc, Izatnagar
T2  - Animal Nutrition and Feed Technology
T1  - Effects of Bentonite on Weight Gain, Feed Consumption, Blood Metabolites and Ruminal Protozoa in Dairy Calves
VL  - 15
IS  - 1
SP  - 11
EP  - 20
DO  - 10.5958/0974-181X.2015.00002.5
ER  - 
@article{
author = "Kirovski, Danijela and Adamović, M. and Radivojević, Mihajlo and Šamanc, Horea and Vujanac, Ivan and Prodanović, Radiša and Sladojević, Željko",
year = "2015",
abstract = "In order to ascertain the effects of addition of bentonite as a pelleting medium in the feed mixture for calves, fourteen 30d-old calves were randomly distributed into two equal groups (CON and EXP). From 30 to 120d of age the EXP group was fed a feed mixture containing 1.5% of natural bentonite while the CON group was fed the same pellets without added bentonite. Body weight was determined before and at the end of the trial. Feed intake was measured daily. Health status was monitored daily. Blood and rumen content samples were taken at 50 and 90d of experiment and analyzed for select parameters. The addition of bentonite had no effect (P > 0.05) on average daily gain, feed intake and health. Blood pH, total number and motility of ruminal protozoa in the EXP group were significantly (P < 0.001, P < 0.05 and P < 0.05; respectively) higher than in CON group at both the periods. At 120d of age the EXP calves had a significantly (P < 0.05, P < 0.05 and P < 0.01; respectively) higher serum total protein, albumin and triglyceride concentrations and lower iron and IGF-I (P < 0.05 and P < 0.01, respectively) concentrations than respective controls values. It is concluded that the use of pelleted feed containing bentonite tended to improve growth of calves as well as the activity of protozoa in the rumen. Additionally, the results indicate a positive influence of the function of hepatocytes concomitant to a reduction in serum iron and IGF-I concentrations.",
publisher = "Animal Nutrition Assoc, Izatnagar",
journal = "Animal Nutrition and Feed Technology",
title = "Effects of Bentonite on Weight Gain, Feed Consumption, Blood Metabolites and Ruminal Protozoa in Dairy Calves",
volume = "15",
number = "1",
pages = "11-20",
doi = "10.5958/0974-181X.2015.00002.5"
}
Kirovski, D., Adamović, M., Radivojević, M., Šamanc, H., Vujanac, I., Prodanović, R.,& Sladojević, Ž.. (2015). Effects of Bentonite on Weight Gain, Feed Consumption, Blood Metabolites and Ruminal Protozoa in Dairy Calves. in Animal Nutrition and Feed Technology
Animal Nutrition Assoc, Izatnagar., 15(1), 11-20.
https://doi.org/10.5958/0974-181X.2015.00002.5
Kirovski D, Adamović M, Radivojević M, Šamanc H, Vujanac I, Prodanović R, Sladojević Ž. Effects of Bentonite on Weight Gain, Feed Consumption, Blood Metabolites and Ruminal Protozoa in Dairy Calves. in Animal Nutrition and Feed Technology. 2015;15(1):11-20.
doi:10.5958/0974-181X.2015.00002.5 .
Kirovski, Danijela, Adamović, M., Radivojević, Mihajlo, Šamanc, Horea, Vujanac, Ivan, Prodanović, Radiša, Sladojević, Željko, "Effects of Bentonite on Weight Gain, Feed Consumption, Blood Metabolites and Ruminal Protozoa in Dairy Calves" in Animal Nutrition and Feed Technology, 15, no. 1 (2015):11-20,
https://doi.org/10.5958/0974-181X.2015.00002.5 . .
4
1
2

The biological significance of differences in cows and sows colostrum and milk composition

Kirovski, Danijela; Vujanac, Ivan; Prodanović, Radiša; Đurić, Miloje; Sladojević, Željko; Savić, Đorđe

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2014)

TY  - JOUR
AU  - Kirovski, Danijela
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Đurić, Miloje
AU  - Sladojević, Željko
AU  - Savić, Đorđe
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1127
AB  - The objective of this work was to compare the composition of colostrum and milk of cows and sows (content of dry matter, protein, milk fat and lactose, concentration of IGF-I and insulin) in samples taken on the first, second, third and seventh day after parturition, and then based on the differences in composition to determine a biological significance of nutrition of newborn during the earliest stages of their life. The investigation included 14 cows of Holstein breed and 14 sows of Landrace breed. The content of dry matter and the concentration of proteins in both colostrum and milk samples were statistically significantly higher in regard to sows mammary glands secretion, taken on the first day after the parturition (p lt 0,01 and p lt 0,001, individually), but their decrease in mammary glands secretion was more pronounced in the cows than the sows, during the first seven days. The concentration IGF-I was statistically significantly higher in the cows colostrum and milk in regard to the sows during the whole investigation period, while the concentration of insulin was significantly higher in the sows in regard to the cows during the same period. The concentrations of milk fat and lactose in cows milk samples were significantly lower in regard to the sows in all period of the study. On the basis of the obtained results, it can be concluded that there are significant differences in the composition of milk and colostrum of both the investigated animal species. The differences are probably the result of evolutionary adaptation of mammal gland function to nutrition, energy and protection requirements of these young animals in their early postnatal life.
AB  - Cilj rada bio je da se uporedi sastav kolostruma i mleka krava i krmača (sadržaj suve materije, proteina, mlečne masti i laktoze, koncentracija IGF-I i insulina) u uzorcima uzetim prvog, drugog, trećeg i sedmog dana nakon porođaja i na osnovu razlika u sastavu ustanovi biološki značaj u ishrani njihovog podmlatka u najranijoj fazi života. U ispitivanje je uključeno 14 krava holštajn rase i 14 krmača rase landras. Procenat suve materije i koncentracija proteina u uzorcima kolostruma i mleka krava bili su statistički značajno viši u odnosu na sekret mlečne žlezde krmače u uzorcima uzetim prvog dana nakon porođaja (p lt 0,01 i p lt 0,001, pojedinačno) ali je smanjenje njihovog sadržaja u sekretu mlečne žlezde tokom prvih sedam dana bilo izraženije kod krava u odnosu na krmače. Koncentracija IGF-I bila je statistički značajno viša u kolostrumu i mleku krava u odnosu na krmače tokom celog perioda ispitivanja, dok je koncentracija insulina bila značajno viša kod krmača u odnosu na krave tokom istog perioda. Koncentracije mlečne masti i laktoze u uzorcima mleka krava bile su značajno niže u odnosu na krmače u svim periodima ispitivanja. Na osnovu dobijenih rezultata može se zaključiti da postoje značajne razlike u sastavu kolostruma i mleka kod dve ispitivane vrste životinja. Te razlike su najverovatnije posledica evolutivnog prilagođavanja funkcije mlečne žlezde nutritivnim, energetskim i zaštitnim potrebama mladunčadi ovih vrsta životinja u panom postnatalnom životu.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - The biological significance of differences in cows and sows colostrum and milk composition
T1  - Biologičeskoe značenie različij v sostave kolostruma i moloka korov i svinomatok
T1  - Biološki značaj razlika u sastavu kolostruma i mleka krava i krmača
VL  - 68
IS  - 3-4
SP  - 175
EP  - 188
DO  - 10.2298/VETGL1404175K
ER  - 
@article{
author = "Kirovski, Danijela and Vujanac, Ivan and Prodanović, Radiša and Đurić, Miloje and Sladojević, Željko and Savić, Đorđe",
year = "2014",
abstract = "The objective of this work was to compare the composition of colostrum and milk of cows and sows (content of dry matter, protein, milk fat and lactose, concentration of IGF-I and insulin) in samples taken on the first, second, third and seventh day after parturition, and then based on the differences in composition to determine a biological significance of nutrition of newborn during the earliest stages of their life. The investigation included 14 cows of Holstein breed and 14 sows of Landrace breed. The content of dry matter and the concentration of proteins in both colostrum and milk samples were statistically significantly higher in regard to sows mammary glands secretion, taken on the first day after the parturition (p lt 0,01 and p lt 0,001, individually), but their decrease in mammary glands secretion was more pronounced in the cows than the sows, during the first seven days. The concentration IGF-I was statistically significantly higher in the cows colostrum and milk in regard to the sows during the whole investigation period, while the concentration of insulin was significantly higher in the sows in regard to the cows during the same period. The concentrations of milk fat and lactose in cows milk samples were significantly lower in regard to the sows in all period of the study. On the basis of the obtained results, it can be concluded that there are significant differences in the composition of milk and colostrum of both the investigated animal species. The differences are probably the result of evolutionary adaptation of mammal gland function to nutrition, energy and protection requirements of these young animals in their early postnatal life., Cilj rada bio je da se uporedi sastav kolostruma i mleka krava i krmača (sadržaj suve materije, proteina, mlečne masti i laktoze, koncentracija IGF-I i insulina) u uzorcima uzetim prvog, drugog, trećeg i sedmog dana nakon porođaja i na osnovu razlika u sastavu ustanovi biološki značaj u ishrani njihovog podmlatka u najranijoj fazi života. U ispitivanje je uključeno 14 krava holštajn rase i 14 krmača rase landras. Procenat suve materije i koncentracija proteina u uzorcima kolostruma i mleka krava bili su statistički značajno viši u odnosu na sekret mlečne žlezde krmače u uzorcima uzetim prvog dana nakon porođaja (p lt 0,01 i p lt 0,001, pojedinačno) ali je smanjenje njihovog sadržaja u sekretu mlečne žlezde tokom prvih sedam dana bilo izraženije kod krava u odnosu na krmače. Koncentracija IGF-I bila je statistički značajno viša u kolostrumu i mleku krava u odnosu na krmače tokom celog perioda ispitivanja, dok je koncentracija insulina bila značajno viša kod krmača u odnosu na krave tokom istog perioda. Koncentracije mlečne masti i laktoze u uzorcima mleka krava bile su značajno niže u odnosu na krmače u svim periodima ispitivanja. Na osnovu dobijenih rezultata može se zaključiti da postoje značajne razlike u sastavu kolostruma i mleka kod dve ispitivane vrste životinja. Te razlike su najverovatnije posledica evolutivnog prilagođavanja funkcije mlečne žlezde nutritivnim, energetskim i zaštitnim potrebama mladunčadi ovih vrsta životinja u panom postnatalnom životu.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "The biological significance of differences in cows and sows colostrum and milk composition, Biologičeskoe značenie različij v sostave kolostruma i moloka korov i svinomatok, Biološki značaj razlika u sastavu kolostruma i mleka krava i krmača",
volume = "68",
number = "3-4",
pages = "175-188",
doi = "10.2298/VETGL1404175K"
}
Kirovski, D., Vujanac, I., Prodanović, R., Đurić, M., Sladojević, Ž.,& Savić, Đ.. (2014). The biological significance of differences in cows and sows colostrum and milk composition. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 68(3-4), 175-188.
https://doi.org/10.2298/VETGL1404175K
Kirovski D, Vujanac I, Prodanović R, Đurić M, Sladojević Ž, Savić Đ. The biological significance of differences in cows and sows colostrum and milk composition. in Veterinarski Glasnik. 2014;68(3-4):175-188.
doi:10.2298/VETGL1404175K .
Kirovski, Danijela, Vujanac, Ivan, Prodanović, Radiša, Đurić, Miloje, Sladojević, Željko, Savić, Đorđe, "The biological significance of differences in cows and sows colostrum and milk composition" in Veterinarski Glasnik, 68, no. 3-4 (2014):175-188,
https://doi.org/10.2298/VETGL1404175K . .
4

Metabolic profile of sows at different parities and with different litter size

Šamanc, Horea; Sladojević, Željko; Vujanac, Ivan; Prodanović, Radiša

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2014)

TY  - JOUR
AU  - Šamanc, Horea
AU  - Sladojević, Željko
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1157
AB  - The aim of this work was to investigate the change of metabolic profile of sows during the lactation period, taking into consideration both parity and number of piglets in a litter (litter size). In order to do this, 30 sows immediately after farrowing were taken and divided into three groups: sows with two farrowing (first group; n=10), ones with four farrowing (second group; n=10), and ones with five and more farrowing (third group; n=10). In regard to a litter size, 20 sows were divided into two groups: sows with eight piglets (first group; n=10), and sows with 10 and more piglets (second group; n=10). All the sows included in the experiment were mestizos of large Yorkshire and Swedish Landrace. Blood samples were taken on the 2nd and 28th day of lactation. In the blood serum samples there were de­termined the concentration of total proteins, albumins, Total bilirubin, calcium and inorganic phosphorus. The results have shown that there was not a significant difference in proteinemia between the groups on the 2nd day after farrowing, while on the 28th day of lactation, proteinemia was significantly lower only in the group with ten or more piglets in a litter. In all the groups, except for the group with ten or more piglets in the litter, proteinemia was significantly higher on the 28th compared to the 2nd day of lactation. Albumin concentration in blood serum of different groups of sows followed the same trend as protein concentration, with the only difference that albuminemia in sows with ten or more piglets in a litter was approximately the same on the 2nd and 28th day of lactation. Total bilirubin concentration in blood serum on the 2nd day after farrowing was equal in different groups of sows, provided that in sows with five or more farrowings it was significantly higher in regard to other groups. Similar divergence was also determined on the 28th day after farrowing. The sows of 4th parity had significantly lower and the ones with 10 or more farrowings higher bilirubinemia on the 28th compared to the 2nd day of lactation. Glycaemia was significantly lower in the sows with ten or more piglets in a litter in regard to other groups both on the 2nd and 28th day of lactation. Calcaemia was significantly lower on the 2nd in regard to the 28th day of lactation in all the groups, except for the group of sows with ten or more piglets in a litter. In the group with 10 or more piglets in a litter, calcaemia was significantly lower compared to other groups both on the 2nd and 28th day. The sows of 4. Parity had significantly lower phosphataemia in regard to other groups both on the 2nd and 28th day of lactation. Moreover, on the 28th day of lactation, the sows with 10 or more piglets in a litter had significantly lower phosphataemia in regard to all the other groups, except for the group of sows of 4th parity. Phosphataemia varied between the 2nd and 28th day of lactation in neither group except for the group of sows with 10 or more piglets in a litter. On the basis of the obtained results it can be concluded that between the 2nd and 28th day of lactation significant changes in concentrations of some parameters of metabolic profile in sows in lactation occur. The determined changes are most pronounced in elderly sows as well as in the ones with ten or more piglets in a litter, being a result of impeded bile flow or metabolic load due to the increased activity of mammary glands.
AB  - Cilj ovoga rada je bio da se ispita promena metaboličkog profila krmača tokom laktacionog perioda, a uzimajući u obzir paritet i broj prasadi u leglu. Za ispitivanje je odabrano 30 krmača neposredno nakon prašenja, koje su prema paritetu podeljene u tri grupe: krmače sa dva prašenja (prva grupa; n=10), sa četiri prašenja (druga grupa; n=10) i sa pet i više prašenja (treća grupa; n=10). U odnosu na broj prasadi u leglu 20 krmača je podeljeno u dve grupe: krmače sa osam i manje prasadi (prva grupa; n=10) i krmače sa 10 i više prasadi (druga grupa; n=10). Sve krmače uključene u ovaj ogled bile su melezi velikog jokšira i švedskog landrasa. Uzorci krvi su uzeti 2. i 28. dan laktacije. U uzorcima krvnog seruma određivana je koncentracija ukupnih proteina, albumina, ukupnog bilirubina, kalcijuma i neorganskog fosfora. Rezultati su pokazali da nije bilo značajne razlike u proteinemiji između grupa 2. dana posle prašenja, dok je 28. dana laktacije proteinemija bila značajno niža jedino kod grupe sa deset i više prasadi u leglu. Kod svih grupa, izuzev grupe sa deset i više prasadi u leglu, proteinemija je bila značajno veća 28. u odnosu na 2. dan laktacije. Koncentracija albumina u krvnom serumu različitih grupa krmača je pratila isti trend kao koncentracija proteina, sa jedinom razlikom što je albuminemija kod krmača sa deset i više prasadi u leglu bila približno ista 2. i 28. dana laktacije. Koncentracija ukupnog bilirubina u krvnom serumu je 2. dana posle prašenja bila približno jednaka kod različitih grupa krmača s tim da je kod krmača sa pet i više prašenja bila značajno veća u odnosu na ostale grupe. Slična razlika između grupa je utvrđena i 28. dana posle prašenja. Krmače 4. pariteta su imale značajno nižu a krmače sa 10 i više prašenje značajno višu bilirubinemiju 28. U odnosu na 2. dan laktacije. Glikemija je bila značajno niža kod krmača sa deset i više prasadi u leglu u odnosu na druge grupe kako 2. tako i 28. dana laktacije. Kalcemija je kod svih grupa, izuzev grupe krmača sa 10 i više prasadi u leglu, bila značajno niža 2. u odnosu na 28. dan. Kod grupe sa 10 i više prasadi u leglu kalcemija je bila značajno niža u odnosu na druge grupe kako 2. tako i 28. dana. Krmače 4. pariteta su imale značajno nižu fosfatemiju u odnosu na ostale grupe 2. i 28. dana lakatcije. Dodatno, 28. dana laktacije krmače sa 10 i više prasadi su imale značajno nižu fosfatemiju u odnosu na sve ostale grupe izuzev grupe krmača 4. pariteta. Fosfatemija se nije razlikovala između 2. i 28. dana laktacije niti kod jedne grupe izuzev kod grupe krmača sa 10 i više prasadi u leglu. Na osnovu dobijenih rezultata može se zaključiti da od 2. do 28. dana laktacije nastaju značajne promene u koncentraciji nekih parametara metaboličkog profila krmača u laktaciji. Ustanovljene promene su najizraženije kod starijih krmača i krmača sa deset i više prasadi u leglu kao rezultat otežanog oticanja žuči ili metaboličkog opterećenja usled pojačane aktivnosti mlečne žlezde.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Metabolic profile of sows at different parities and with different litter size
T1  - Metaboličeskij profil' svinomatok raznogo pariteta i količestva porosjat v pomete
T1  - Metabolički profil krmača različitog pariteta i broja prasadi u leglu
VL  - 68
IS  - 1-2
SP  - 77
EP  - 88
DO  - 10.2298/VETGL1402077S
ER  - 
@article{
author = "Šamanc, Horea and Sladojević, Željko and Vujanac, Ivan and Prodanović, Radiša",
year = "2014",
abstract = "The aim of this work was to investigate the change of metabolic profile of sows during the lactation period, taking into consideration both parity and number of piglets in a litter (litter size). In order to do this, 30 sows immediately after farrowing were taken and divided into three groups: sows with two farrowing (first group; n=10), ones with four farrowing (second group; n=10), and ones with five and more farrowing (third group; n=10). In regard to a litter size, 20 sows were divided into two groups: sows with eight piglets (first group; n=10), and sows with 10 and more piglets (second group; n=10). All the sows included in the experiment were mestizos of large Yorkshire and Swedish Landrace. Blood samples were taken on the 2nd and 28th day of lactation. In the blood serum samples there were de­termined the concentration of total proteins, albumins, Total bilirubin, calcium and inorganic phosphorus. The results have shown that there was not a significant difference in proteinemia between the groups on the 2nd day after farrowing, while on the 28th day of lactation, proteinemia was significantly lower only in the group with ten or more piglets in a litter. In all the groups, except for the group with ten or more piglets in the litter, proteinemia was significantly higher on the 28th compared to the 2nd day of lactation. Albumin concentration in blood serum of different groups of sows followed the same trend as protein concentration, with the only difference that albuminemia in sows with ten or more piglets in a litter was approximately the same on the 2nd and 28th day of lactation. Total bilirubin concentration in blood serum on the 2nd day after farrowing was equal in different groups of sows, provided that in sows with five or more farrowings it was significantly higher in regard to other groups. Similar divergence was also determined on the 28th day after farrowing. The sows of 4th parity had significantly lower and the ones with 10 or more farrowings higher bilirubinemia on the 28th compared to the 2nd day of lactation. Glycaemia was significantly lower in the sows with ten or more piglets in a litter in regard to other groups both on the 2nd and 28th day of lactation. Calcaemia was significantly lower on the 2nd in regard to the 28th day of lactation in all the groups, except for the group of sows with ten or more piglets in a litter. In the group with 10 or more piglets in a litter, calcaemia was significantly lower compared to other groups both on the 2nd and 28th day. The sows of 4. Parity had significantly lower phosphataemia in regard to other groups both on the 2nd and 28th day of lactation. Moreover, on the 28th day of lactation, the sows with 10 or more piglets in a litter had significantly lower phosphataemia in regard to all the other groups, except for the group of sows of 4th parity. Phosphataemia varied between the 2nd and 28th day of lactation in neither group except for the group of sows with 10 or more piglets in a litter. On the basis of the obtained results it can be concluded that between the 2nd and 28th day of lactation significant changes in concentrations of some parameters of metabolic profile in sows in lactation occur. The determined changes are most pronounced in elderly sows as well as in the ones with ten or more piglets in a litter, being a result of impeded bile flow or metabolic load due to the increased activity of mammary glands., Cilj ovoga rada je bio da se ispita promena metaboličkog profila krmača tokom laktacionog perioda, a uzimajući u obzir paritet i broj prasadi u leglu. Za ispitivanje je odabrano 30 krmača neposredno nakon prašenja, koje su prema paritetu podeljene u tri grupe: krmače sa dva prašenja (prva grupa; n=10), sa četiri prašenja (druga grupa; n=10) i sa pet i više prašenja (treća grupa; n=10). U odnosu na broj prasadi u leglu 20 krmača je podeljeno u dve grupe: krmače sa osam i manje prasadi (prva grupa; n=10) i krmače sa 10 i više prasadi (druga grupa; n=10). Sve krmače uključene u ovaj ogled bile su melezi velikog jokšira i švedskog landrasa. Uzorci krvi su uzeti 2. i 28. dan laktacije. U uzorcima krvnog seruma određivana je koncentracija ukupnih proteina, albumina, ukupnog bilirubina, kalcijuma i neorganskog fosfora. Rezultati su pokazali da nije bilo značajne razlike u proteinemiji između grupa 2. dana posle prašenja, dok je 28. dana laktacije proteinemija bila značajno niža jedino kod grupe sa deset i više prasadi u leglu. Kod svih grupa, izuzev grupe sa deset i više prasadi u leglu, proteinemija je bila značajno veća 28. u odnosu na 2. dan laktacije. Koncentracija albumina u krvnom serumu različitih grupa krmača je pratila isti trend kao koncentracija proteina, sa jedinom razlikom što je albuminemija kod krmača sa deset i više prasadi u leglu bila približno ista 2. i 28. dana laktacije. Koncentracija ukupnog bilirubina u krvnom serumu je 2. dana posle prašenja bila približno jednaka kod različitih grupa krmača s tim da je kod krmača sa pet i više prašenja bila značajno veća u odnosu na ostale grupe. Slična razlika između grupa je utvrđena i 28. dana posle prašenja. Krmače 4. pariteta su imale značajno nižu a krmače sa 10 i više prašenje značajno višu bilirubinemiju 28. U odnosu na 2. dan laktacije. Glikemija je bila značajno niža kod krmača sa deset i više prasadi u leglu u odnosu na druge grupe kako 2. tako i 28. dana laktacije. Kalcemija je kod svih grupa, izuzev grupe krmača sa 10 i više prasadi u leglu, bila značajno niža 2. u odnosu na 28. dan. Kod grupe sa 10 i više prasadi u leglu kalcemija je bila značajno niža u odnosu na druge grupe kako 2. tako i 28. dana. Krmače 4. pariteta su imale značajno nižu fosfatemiju u odnosu na ostale grupe 2. i 28. dana lakatcije. Dodatno, 28. dana laktacije krmače sa 10 i više prasadi su imale značajno nižu fosfatemiju u odnosu na sve ostale grupe izuzev grupe krmača 4. pariteta. Fosfatemija se nije razlikovala između 2. i 28. dana laktacije niti kod jedne grupe izuzev kod grupe krmača sa 10 i više prasadi u leglu. Na osnovu dobijenih rezultata može se zaključiti da od 2. do 28. dana laktacije nastaju značajne promene u koncentraciji nekih parametara metaboličkog profila krmača u laktaciji. Ustanovljene promene su najizraženije kod starijih krmača i krmača sa deset i više prasadi u leglu kao rezultat otežanog oticanja žuči ili metaboličkog opterećenja usled pojačane aktivnosti mlečne žlezde.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Metabolic profile of sows at different parities and with different litter size, Metaboličeskij profil' svinomatok raznogo pariteta i količestva porosjat v pomete, Metabolički profil krmača različitog pariteta i broja prasadi u leglu",
volume = "68",
number = "1-2",
pages = "77-88",
doi = "10.2298/VETGL1402077S"
}
Šamanc, H., Sladojević, Ž., Vujanac, I.,& Prodanović, R.. (2014). Metabolic profile of sows at different parities and with different litter size. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 68(1-2), 77-88.
https://doi.org/10.2298/VETGL1402077S
Šamanc H, Sladojević Ž, Vujanac I, Prodanović R. Metabolic profile of sows at different parities and with different litter size. in Veterinarski Glasnik. 2014;68(1-2):77-88.
doi:10.2298/VETGL1402077S .
Šamanc, Horea, Sladojević, Željko, Vujanac, Ivan, Prodanović, Radiša, "Metabolic profile of sows at different parities and with different litter size" in Veterinarski Glasnik, 68, no. 1-2 (2014):77-88,
https://doi.org/10.2298/VETGL1402077S . .

A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield

Šamanc, Horea; Kirovski, Danijela; Lakić, Nada; Celeska, Irena; Bojkovic-Kovacević, Slavica; Sladojević, Željko; Ivanov, Ivan

(Akademiai Kiado Rt, Budapest, 2014)

TY  - JOUR
AU  - Šamanc, Horea
AU  - Kirovski, Danijela
AU  - Lakić, Nada
AU  - Celeska, Irena
AU  - Bojkovic-Kovacević, Slavica
AU  - Sladojević, Željko
AU  - Ivanov, Ivan
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1105
AB  - The aim of this study was to compare the concentrations of blood variables obtained simultaneously from the jugular and mammary veins of dairy cows. Eighty Holstein cows were divided into four equal groups: dry, low- (LY), medium- (MY) and high-yielding (HY). Blood insulin, glucose, non-esterified fatty acid (NEFA), beta-hydroxybutyrate (BHBA) and urea concentrations were measured. The jugular and mammary vein (J/M) ratio between concentrations of each variable was calculated. Differences between the groups of cows in concentrations of variables in the jugular vein were not in accordance with those obtained for the mammary vein. J/M values for insulin and glucose concentrations were above 1.0 in all groups of cows. The ratios for NEFA and BHBA concentrations were under or equal to 1.0 in dry and LY cows but above 1.0 in the MY and HY groups, indicating that in MY and HY cows those metabolites are apparently utilised by the mammary gland. J/M values for urea were above 1.0 in dry and LY cows but less than 1.0 in groups MY and HY, indicating that in the latter case urea is apparently released by the mammary gland. In conclusion, J/M for NEFA, BHBA and urea may be useful for estimation of the critical point when the mammary gland receives insufficient energy precursors for its current activity.
PB  - Akademiai Kiado Rt, Budapest
T2  - Acta Veterinaria Hungarica
T1  - A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield
VL  - 62
IS  - 1
SP  - 52
EP  - 63
DO  - 10.1556/AVet.2013.055
ER  - 
@article{
author = "Šamanc, Horea and Kirovski, Danijela and Lakić, Nada and Celeska, Irena and Bojkovic-Kovacević, Slavica and Sladojević, Željko and Ivanov, Ivan",
year = "2014",
abstract = "The aim of this study was to compare the concentrations of blood variables obtained simultaneously from the jugular and mammary veins of dairy cows. Eighty Holstein cows were divided into four equal groups: dry, low- (LY), medium- (MY) and high-yielding (HY). Blood insulin, glucose, non-esterified fatty acid (NEFA), beta-hydroxybutyrate (BHBA) and urea concentrations were measured. The jugular and mammary vein (J/M) ratio between concentrations of each variable was calculated. Differences between the groups of cows in concentrations of variables in the jugular vein were not in accordance with those obtained for the mammary vein. J/M values for insulin and glucose concentrations were above 1.0 in all groups of cows. The ratios for NEFA and BHBA concentrations were under or equal to 1.0 in dry and LY cows but above 1.0 in the MY and HY groups, indicating that in MY and HY cows those metabolites are apparently utilised by the mammary gland. J/M values for urea were above 1.0 in dry and LY cows but less than 1.0 in groups MY and HY, indicating that in the latter case urea is apparently released by the mammary gland. In conclusion, J/M for NEFA, BHBA and urea may be useful for estimation of the critical point when the mammary gland receives insufficient energy precursors for its current activity.",
publisher = "Akademiai Kiado Rt, Budapest",
journal = "Acta Veterinaria Hungarica",
title = "A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield",
volume = "62",
number = "1",
pages = "52-63",
doi = "10.1556/AVet.2013.055"
}
Šamanc, H., Kirovski, D., Lakić, N., Celeska, I., Bojkovic-Kovacević, S., Sladojević, Ž.,& Ivanov, I.. (2014). A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield. in Acta Veterinaria Hungarica
Akademiai Kiado Rt, Budapest., 62(1), 52-63.
https://doi.org/10.1556/AVet.2013.055
Šamanc H, Kirovski D, Lakić N, Celeska I, Bojkovic-Kovacević S, Sladojević Ž, Ivanov I. A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield. in Acta Veterinaria Hungarica. 2014;62(1):52-63.
doi:10.1556/AVet.2013.055 .
Šamanc, Horea, Kirovski, Danijela, Lakić, Nada, Celeska, Irena, Bojkovic-Kovacević, Slavica, Sladojević, Željko, Ivanov, Ivan, "A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield" in Acta Veterinaria Hungarica, 62, no. 1 (2014):52-63,
https://doi.org/10.1556/AVet.2013.055 . .
3
2
3

Neki aspekti etiopatogeneze poremećaja u ponašanju krava u farmskim uslovima držanja

Prodanović, Radiša; Šamanc, Horea; Kirovski, Danijela; Vujanac, Ivan; Sladojević, Željko

(Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“, 2013)

TY  - JOUR
AU  - Prodanović, Radiša
AU  - Šamanc, Horea
AU  - Kirovski, Danijela
AU  - Vujanac, Ivan
AU  - Sladojević, Željko
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2109
AB  - Циљ рада био је да се утврди повезаност биохемијских параметара крви и
стереотипног понашања крава. Испитивање је извршено на 80 Холштајн крава
подељених у четири групе: засушење, пуерперијум, рана и касна лактацијa.
Процена стереотипног понашања (игра језика) извршена је посматрањем живо-
тиња 2–4 часа након јутарњег храњења. У узорцима крви одређиване су концен-
трације најважнијих биохемијских параметара крви. Поремећаји у виду „игре
језика“ су установљени код три од 20 животиња из пуерпералне групе крава
када су установљене и значајно ниже вредности гликемије, протеинемије, уре-
мије и магнезијемије у односу на антепарталне вредности. Концентрације били-
рубина су у том периоду биле изнад, а укупних протеина и магнезијума испод
физиолошких вредности. Резултати указују на вероватну повезаност испити-
ваног стереотипног понашања и биохемијског састава крви.
AB  - The objective of this study was to determine the relationship between
stereotyped behavior and selected biochemical parameters in dairy cows. A total of
80 Holstein cows were randomly assigned into one of 4 groups: dry, puerperal,
early and late lactating. Evaluation of stereotypes (tongue rolling) was performed
by observation of animals 2 to 4 hours after morning feeding. Blood samples were taken and analyzed for main biochemical parameters. Tongue rolling was
established in 3 of 20 puerperal cows. Puerperal cows had significantly lower
values for glicemia, proteinemia, uremia and magnesiemia compared to antepartal
cows. Total protein and Mg were below, whereas total bilirubin was above
physiological ranges. These results support the possibility to link blood changes to
the occurrence of changed behaviour.
PB  - Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“
T2  - Veterinarski žurnal Republike Srpske
T1  - Neki aspekti etiopatogeneze poremećaja u ponašanju krava u farmskim uslovima držanja
T1  - Some aspects of the etiopathogenesis of behaviour problems among cows in intesive housing conditions
VL  - 13
IS  - 2
SP  - 221
EP  - 228
DO  - 10.7251/VJRS1302221P
ER  - 
@article{
author = "Prodanović, Radiša and Šamanc, Horea and Kirovski, Danijela and Vujanac, Ivan and Sladojević, Željko",
year = "2013",
abstract = "Циљ рада био је да се утврди повезаност биохемијских параметара крви и
стереотипног понашања крава. Испитивање је извршено на 80 Холштајн крава
подељених у четири групе: засушење, пуерперијум, рана и касна лактацијa.
Процена стереотипног понашања (игра језика) извршена је посматрањем живо-
тиња 2–4 часа након јутарњег храњења. У узорцима крви одређиване су концен-
трације најважнијих биохемијских параметара крви. Поремећаји у виду „игре
језика“ су установљени код три од 20 животиња из пуерпералне групе крава
када су установљене и значајно ниже вредности гликемије, протеинемије, уре-
мије и магнезијемије у односу на антепарталне вредности. Концентрације били-
рубина су у том периоду биле изнад, а укупних протеина и магнезијума испод
физиолошких вредности. Резултати указују на вероватну повезаност испити-
ваног стереотипног понашања и биохемијског састава крви., The objective of this study was to determine the relationship between
stereotyped behavior and selected biochemical parameters in dairy cows. A total of
80 Holstein cows were randomly assigned into one of 4 groups: dry, puerperal,
early and late lactating. Evaluation of stereotypes (tongue rolling) was performed
by observation of animals 2 to 4 hours after morning feeding. Blood samples were taken and analyzed for main biochemical parameters. Tongue rolling was
established in 3 of 20 puerperal cows. Puerperal cows had significantly lower
values for glicemia, proteinemia, uremia and magnesiemia compared to antepartal
cows. Total protein and Mg were below, whereas total bilirubin was above
physiological ranges. These results support the possibility to link blood changes to
the occurrence of changed behaviour.",
publisher = "Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“",
journal = "Veterinarski žurnal Republike Srpske",
title = "Neki aspekti etiopatogeneze poremećaja u ponašanju krava u farmskim uslovima držanja, Some aspects of the etiopathogenesis of behaviour problems among cows in intesive housing conditions",
volume = "13",
number = "2",
pages = "221-228",
doi = "10.7251/VJRS1302221P"
}
Prodanović, R., Šamanc, H., Kirovski, D., Vujanac, I.,& Sladojević, Ž.. (2013). Neki aspekti etiopatogeneze poremećaja u ponašanju krava u farmskim uslovima držanja. in Veterinarski žurnal Republike Srpske
Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“., 13(2), 221-228.
https://doi.org/10.7251/VJRS1302221P
Prodanović R, Šamanc H, Kirovski D, Vujanac I, Sladojević Ž. Neki aspekti etiopatogeneze poremećaja u ponašanju krava u farmskim uslovima držanja. in Veterinarski žurnal Republike Srpske. 2013;13(2):221-228.
doi:10.7251/VJRS1302221P .
Prodanović, Radiša, Šamanc, Horea, Kirovski, Danijela, Vujanac, Ivan, Sladojević, Željko, "Neki aspekti etiopatogeneze poremećaja u ponašanju krava u farmskim uslovima držanja" in Veterinarski žurnal Republike Srpske, 13, no. 2 (2013):221-228,
https://doi.org/10.7251/VJRS1302221P . .

Uticaj energetskog dodatka na bazi glicerola na tjelesnu kondiciju visokomliječnih krava

Sladojević, Željko; Kirovski, Danijela; Šamanc, Horea

(Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“, 2013)

TY  - JOUR
AU  - Sladojević, Željko
AU  - Kirovski, Danijela
AU  - Šamanc, Horea
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2108
AB  - Циљ рада је био да се утврди утицај енергетског додатка на бази глицерола
на тjелесну кондицију крава. Петнаест дана прије тељења одабрано је 80 крава
подијељених у двије групе од по 40 крава: контролну и огледну. Кравама
огледне групе је у посљедње двије недјеље засушења и до 60. дана лактације
додаван у храну енергетски додатак на бази глицерола. Оцјена тјелесне
кондиције (ОТК) одређена је 15 дана прије, као и 7, 30 и 60 дана послије
тељења. Краве огледне групе су имале значајно вишу вриједност ОТК у односу
на контролну групу само 7. дана лактације. Разлика у ОТК између периода
засушења и пуерперијума је била у оквиру физиолошки дозвољеног опсега
вриједности код огледне групе, док је код контролне групе била виша од
дозвољеног, указујући да је код огледних крава постпартални негативан биланс
енергије био слабије изражен.
AB  - The objective of the investigation presented in this study was to establish the
effects of a glycerol-based energy supplement in the diet of high-yield dairy cows
on their body condition. Eighty cows were selected 2 weeks before calving, and
they were divided into two groups with 40 cows: control and experimental. Cows of the experimental group orally received glycerol based energy supplement during
the final two weeks of the dry period until the day 60 of lactation. Body condition
scoring (BCS) was done 15 days before and 7, 30 and 60 days after calving.
Experimental cows had significantly higher BCS only on day 7 after calving
compared to control group. Difference in BCS between dry and puerperal period
was within physiological value in experimental but higher than physiologically
accepted in control group, indicating that negative energy balance in experimental
cows was not so pronounced.
PB  - Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“
T2  - Veterinarski žurnal Republike Srpske
T1  - Uticaj energetskog dodatka na bazi glicerola na tjelesnu kondiciju visokomliječnih krava
T1  - Effect of glycerol based energy supplementation on body condition score of dairy cows
VL  - 13
IS  - 2
SP  - 211
EP  - 220
DO  - 10.7251/VJRS1302211S
ER  - 
@article{
author = "Sladojević, Željko and Kirovski, Danijela and Šamanc, Horea",
year = "2013",
abstract = "Циљ рада је био да се утврди утицај енергетског додатка на бази глицерола
на тjелесну кондицију крава. Петнаест дана прије тељења одабрано је 80 крава
подијељених у двије групе од по 40 крава: контролну и огледну. Кравама
огледне групе је у посљедње двије недјеље засушења и до 60. дана лактације
додаван у храну енергетски додатак на бази глицерола. Оцјена тјелесне
кондиције (ОТК) одређена је 15 дана прије, као и 7, 30 и 60 дана послије
тељења. Краве огледне групе су имале значајно вишу вриједност ОТК у односу
на контролну групу само 7. дана лактације. Разлика у ОТК између периода
засушења и пуерперијума је била у оквиру физиолошки дозвољеног опсега
вриједности код огледне групе, док је код контролне групе била виша од
дозвољеног, указујући да је код огледних крава постпартални негативан биланс
енергије био слабије изражен., The objective of the investigation presented in this study was to establish the
effects of a glycerol-based energy supplement in the diet of high-yield dairy cows
on their body condition. Eighty cows were selected 2 weeks before calving, and
they were divided into two groups with 40 cows: control and experimental. Cows of the experimental group orally received glycerol based energy supplement during
the final two weeks of the dry period until the day 60 of lactation. Body condition
scoring (BCS) was done 15 days before and 7, 30 and 60 days after calving.
Experimental cows had significantly higher BCS only on day 7 after calving
compared to control group. Difference in BCS between dry and puerperal period
was within physiological value in experimental but higher than physiologically
accepted in control group, indicating that negative energy balance in experimental
cows was not so pronounced.",
publisher = "Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“",
journal = "Veterinarski žurnal Republike Srpske",
title = "Uticaj energetskog dodatka na bazi glicerola na tjelesnu kondiciju visokomliječnih krava, Effect of glycerol based energy supplementation on body condition score of dairy cows",
volume = "13",
number = "2",
pages = "211-220",
doi = "10.7251/VJRS1302211S"
}
Sladojević, Ž., Kirovski, D.,& Šamanc, H.. (2013). Uticaj energetskog dodatka na bazi glicerola na tjelesnu kondiciju visokomliječnih krava. in Veterinarski žurnal Republike Srpske
Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“., 13(2), 211-220.
https://doi.org/10.7251/VJRS1302211S
Sladojević Ž, Kirovski D, Šamanc H. Uticaj energetskog dodatka na bazi glicerola na tjelesnu kondiciju visokomliječnih krava. in Veterinarski žurnal Republike Srpske. 2013;13(2):211-220.
doi:10.7251/VJRS1302211S .
Sladojević, Željko, Kirovski, Danijela, Šamanc, Horea, "Uticaj energetskog dodatka na bazi glicerola na tjelesnu kondiciju visokomliječnih krava" in Veterinarski žurnal Republike Srpske, 13, no. 2 (2013):211-220,
https://doi.org/10.7251/VJRS1302211S . .

Nutritivni status visokomlečnih krava: procena na osnovu sastava mleka

Kirovski, Danijela; Šamanc, Horea; Sladojević, Željko; Prodanović, Radiša; Vujanac, Ivan

(Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“, 2013)

TY  - JOUR
AU  - Kirovski, Danijela
AU  - Šamanc, Horea
AU  - Sladojević, Željko
AU  - Prodanović, Radiša
AU  - Vujanac, Ivan
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2100
AB  - За испитивање је узорковано млеко добијено од сто крава 30. дана лактације
током јутарње и вечерње муже. Анализом резултата установљено је да су краве
биле у стању негативног биланса енергије. Није било значајне разлике у концентрацији масти и протеина између јутарње и вечерње муже, али је концентрација урее била значајно виша током јутарње муже, указујући да су јединке
током ноћи гладовале односно да је распон између вечерњег и јутарњег храњења био значајно дужи. Због тога, протеини хране нису могли да буду искоришћени за синтезу високовредних протеина, већ су се њихови производи разлагања конвертовали у уреу, која се излучивала путем млека.
AB  - Investigation was done using morning and evening milk samples from 100 cows
that were 30 days in lactation. Obtained results showed that all cows were in state
on negative energy balance. There was no significant difference between morning
and evening milk samples in fat and protein concentrations, but urea concentration
was significantly higher in morning compared to evening milk samples,
indicating that cows were exposed to over-night starvation, meaning that period between evening and morning feeding were to long. Therefore, dietary proteins
were not used for synthesis of animal proteins but were converted to urea that was
excreted by milk.
PB  - Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“
T2  - Veterinarski žurnal Republike Srpske
T1  - Nutritivni status visokomlečnih krava: procena na osnovu sastava mleka
T1  - Nutritional status of dairy cows: estimation based on milk composition
VL  - 13
IS  - 2
SP  - 109
EP  - 116
DO  - 10.7251/VJRS1302109K
ER  - 
@article{
author = "Kirovski, Danijela and Šamanc, Horea and Sladojević, Željko and Prodanović, Radiša and Vujanac, Ivan",
year = "2013",
abstract = "За испитивање је узорковано млеко добијено од сто крава 30. дана лактације
током јутарње и вечерње муже. Анализом резултата установљено је да су краве
биле у стању негативног биланса енергије. Није било значајне разлике у концентрацији масти и протеина између јутарње и вечерње муже, али је концентрација урее била значајно виша током јутарње муже, указујући да су јединке
током ноћи гладовале односно да је распон између вечерњег и јутарњег храњења био значајно дужи. Због тога, протеини хране нису могли да буду искоришћени за синтезу високовредних протеина, већ су се њихови производи разлагања конвертовали у уреу, која се излучивала путем млека., Investigation was done using morning and evening milk samples from 100 cows
that were 30 days in lactation. Obtained results showed that all cows were in state
on negative energy balance. There was no significant difference between morning
and evening milk samples in fat and protein concentrations, but urea concentration
was significantly higher in morning compared to evening milk samples,
indicating that cows were exposed to over-night starvation, meaning that period between evening and morning feeding were to long. Therefore, dietary proteins
were not used for synthesis of animal proteins but were converted to urea that was
excreted by milk.",
publisher = "Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“",
journal = "Veterinarski žurnal Republike Srpske",
title = "Nutritivni status visokomlečnih krava: procena na osnovu sastava mleka, Nutritional status of dairy cows: estimation based on milk composition",
volume = "13",
number = "2",
pages = "109-116",
doi = "10.7251/VJRS1302109K"
}
Kirovski, D., Šamanc, H., Sladojević, Ž., Prodanović, R.,& Vujanac, I.. (2013). Nutritivni status visokomlečnih krava: procena na osnovu sastava mleka. in Veterinarski žurnal Republike Srpske
Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“., 13(2), 109-116.
https://doi.org/10.7251/VJRS1302109K
Kirovski D, Šamanc H, Sladojević Ž, Prodanović R, Vujanac I. Nutritivni status visokomlečnih krava: procena na osnovu sastava mleka. in Veterinarski žurnal Republike Srpske. 2013;13(2):109-116.
doi:10.7251/VJRS1302109K .
Kirovski, Danijela, Šamanc, Horea, Sladojević, Željko, Prodanović, Radiša, Vujanac, Ivan, "Nutritivni status visokomlečnih krava: procena na osnovu sastava mleka" in Veterinarski žurnal Republike Srpske, 13, no. 2 (2013):109-116,
https://doi.org/10.7251/VJRS1302109K . .

Relationship between growth of nursing pigs and composition of sow colostrum and milk from anterior and posterior mammary glands

Šamanc, Horea; Sladojević, Željko; Vujanac, Ivan; Prodanović, Radiša; Kirovski, M.; Dodovski, Petar; Kirovski, Danijela

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2013)

TY  - JOUR
AU  - Šamanc, Horea
AU  - Sladojević, Željko
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Kirovski, M.
AU  - Dodovski, Petar
AU  - Kirovski, Danijela
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1073
AB  - Piglets that nurse anterior mammary glands grow faster than those suckling posterior mammary glands. The underlying mechanisms are not known. The purpose of this study was to investigate if there is a difference in composition in colostrum and milk secreted by anterior and posterior mammary glands. Seven healthy sows were used. The first three pairs of mammary glands were defined as anterior mammary glands (AMG) and the rest as posterior mammary glands (PMG). Additionally, the total of 87 born piglets from 7 litters derived from the sows involved in the experiment was analyzed. Piglets from each litter that nursed AMG were defined as AMG group while the rest of piglets from the litter were defined as PMG group. Colostrum and milk were collected at days 1, 2, 3 and 7 after parturition. Samples taken from anterior and posterior mammary glands were pooled, respectively. Results showed that total protein, IGF-I and insulin concentrations were significantly higher in the colostrum of anterior than posterior glands and IGF-I concentration remained significantly higher in milk of anterior compared to posterior glands. There were no significant differences in fat, dry matter and lactose among anterior and posterior glands during all examined periods. Additionally, blood samples from nursing sows were obtained at days 1 and 7 after parturition. Results showed that concentrations of Ca, glucose, total protein, albumin, globulin, total bilirubin and insulin significantly increased from day 1 to day 7 of parturition while concentrations of P, BUN, CK and IGF-I did not significantly change during this period. Initial body weight of pigs nursing the anterior gland was higher but not significantly that those suckling posterior glands. Pigs that nursed anterior glands gained weight faster then those which suckled posterior glands resulting with significantly higher body weigh of piglets nursing anterior compared to posterior glands at day 8 of neonatal life (p  lt  0.05). Therefore, it may be concluded that the priority of anterior glands milk secretion in total protein and grow stimulating factors may have an impact on increased body weight gain of nursing pigs.
AB  - Prasad koja sisaju prednje mamarne komplekse rastu brže nego ona koja sisaju zadnje. Mehanizmi koji objašnjavaju ovu pojavu nisu sasvim poznati. Cilj ovog rada bio je da se ispita da li postoji razlika u sastavu kolostruma i mleka stvorenim u prednjim odnosno zadnjim mamarnim kompleksima. Sedam zdravih krmača je bilo uključeno u ogled. Prva tri para mamarnih kompleksa su definisana kao prednji (PMK), a ostali kao zadnji mamarni kompleksi (ZMK). Dodatno, ispitano je 87 prasadi iz 7 legala poreklom od krmača uključenih u ogled. Prasad iz legla koja su sisala PMK su pripala PMK grupi dok su prasad koja su sisala preostale mamarne komplekse grupisana u ZMK grupu. Kolostrum i mleko su uzorkovani 1., 2., 3. i 7. dana nakon prašenja. Uzorci uzeti iz prednjih odnosno zadnjih mamarnih kompleksa su zatim spojeni. Rezultati su ukazali da su koncentracije ukupnih proteina, IGF-I i insulina bile značajno više u kolostrumu PMK u odnosu na ZMK a koncentracija IGF-I je ostala značajno viša u mleku PMK u odnosu na ZMK. Nije bilo značajne razlike u koncentraciji masti, suvoj materiji i laktozi između sekreta PMK i ZMK tokom celog ispitivanog perioda. Dodatno, uzimani su uzorci krvi od krmača 1. i 7. dana posle prašenja. Rezultati su ukazali da su koncentracije Ca, glukoze, ukupnih proteina, albumina, globulina, ukupnog bilirubina i insulina značajno porasle od 1. do 7. dana nakon prašenja dok se koncentracija P, uree, kreatin kinaze i IGF-I nije značajno menjala tokom ovog perioda. Početna telesna masa prasadi koja su sisala PMK je bila viša, ali ne značajno, u odnosu na onu koju je sisalo ZMK. Posle toga, prasad koja su sisala PMK su imala veći dnevni telesni prirast nego ona koja su sisala ZMK što je rezultiralo da su 8. dana neonatalnog života prasad koja su sisala PMK imala značajno veću telesnu masu u odnosu na onu koja su sisala ZMK. Na osnovu svega navedenog se može zaključiti da kvalitetniji sastav sekreta PMK u pogledu sadržaja proteina i faktora rasta može da ima uticaj na veći telesni prirast prasadi koja sisaju ove komplekse u odnosu na prasad koja sisaju ZMK.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Relationship between growth of nursing pigs and composition of sow colostrum and milk from anterior and posterior mammary glands
T1  - Zavisnost rasta novorođene prasadi od sastava kolostruma i mleka prednjih odnosno zadnjih mamarnih kompleksa krmača
VL  - 63
IS  - 5-6
SP  - 537
EP  - 548
DO  - 10.2298/AVB1306537S
ER  - 
@article{
author = "Šamanc, Horea and Sladojević, Željko and Vujanac, Ivan and Prodanović, Radiša and Kirovski, M. and Dodovski, Petar and Kirovski, Danijela",
year = "2013",
abstract = "Piglets that nurse anterior mammary glands grow faster than those suckling posterior mammary glands. The underlying mechanisms are not known. The purpose of this study was to investigate if there is a difference in composition in colostrum and milk secreted by anterior and posterior mammary glands. Seven healthy sows were used. The first three pairs of mammary glands were defined as anterior mammary glands (AMG) and the rest as posterior mammary glands (PMG). Additionally, the total of 87 born piglets from 7 litters derived from the sows involved in the experiment was analyzed. Piglets from each litter that nursed AMG were defined as AMG group while the rest of piglets from the litter were defined as PMG group. Colostrum and milk were collected at days 1, 2, 3 and 7 after parturition. Samples taken from anterior and posterior mammary glands were pooled, respectively. Results showed that total protein, IGF-I and insulin concentrations were significantly higher in the colostrum of anterior than posterior glands and IGF-I concentration remained significantly higher in milk of anterior compared to posterior glands. There were no significant differences in fat, dry matter and lactose among anterior and posterior glands during all examined periods. Additionally, blood samples from nursing sows were obtained at days 1 and 7 after parturition. Results showed that concentrations of Ca, glucose, total protein, albumin, globulin, total bilirubin and insulin significantly increased from day 1 to day 7 of parturition while concentrations of P, BUN, CK and IGF-I did not significantly change during this period. Initial body weight of pigs nursing the anterior gland was higher but not significantly that those suckling posterior glands. Pigs that nursed anterior glands gained weight faster then those which suckled posterior glands resulting with significantly higher body weigh of piglets nursing anterior compared to posterior glands at day 8 of neonatal life (p  lt  0.05). Therefore, it may be concluded that the priority of anterior glands milk secretion in total protein and grow stimulating factors may have an impact on increased body weight gain of nursing pigs., Prasad koja sisaju prednje mamarne komplekse rastu brže nego ona koja sisaju zadnje. Mehanizmi koji objašnjavaju ovu pojavu nisu sasvim poznati. Cilj ovog rada bio je da se ispita da li postoji razlika u sastavu kolostruma i mleka stvorenim u prednjim odnosno zadnjim mamarnim kompleksima. Sedam zdravih krmača je bilo uključeno u ogled. Prva tri para mamarnih kompleksa su definisana kao prednji (PMK), a ostali kao zadnji mamarni kompleksi (ZMK). Dodatno, ispitano je 87 prasadi iz 7 legala poreklom od krmača uključenih u ogled. Prasad iz legla koja su sisala PMK su pripala PMK grupi dok su prasad koja su sisala preostale mamarne komplekse grupisana u ZMK grupu. Kolostrum i mleko su uzorkovani 1., 2., 3. i 7. dana nakon prašenja. Uzorci uzeti iz prednjih odnosno zadnjih mamarnih kompleksa su zatim spojeni. Rezultati su ukazali da su koncentracije ukupnih proteina, IGF-I i insulina bile značajno više u kolostrumu PMK u odnosu na ZMK a koncentracija IGF-I je ostala značajno viša u mleku PMK u odnosu na ZMK. Nije bilo značajne razlike u koncentraciji masti, suvoj materiji i laktozi između sekreta PMK i ZMK tokom celog ispitivanog perioda. Dodatno, uzimani su uzorci krvi od krmača 1. i 7. dana posle prašenja. Rezultati su ukazali da su koncentracije Ca, glukoze, ukupnih proteina, albumina, globulina, ukupnog bilirubina i insulina značajno porasle od 1. do 7. dana nakon prašenja dok se koncentracija P, uree, kreatin kinaze i IGF-I nije značajno menjala tokom ovog perioda. Početna telesna masa prasadi koja su sisala PMK je bila viša, ali ne značajno, u odnosu na onu koju je sisalo ZMK. Posle toga, prasad koja su sisala PMK su imala veći dnevni telesni prirast nego ona koja su sisala ZMK što je rezultiralo da su 8. dana neonatalnog života prasad koja su sisala PMK imala značajno veću telesnu masu u odnosu na onu koja su sisala ZMK. Na osnovu svega navedenog se može zaključiti da kvalitetniji sastav sekreta PMK u pogledu sadržaja proteina i faktora rasta može da ima uticaj na veći telesni prirast prasadi koja sisaju ove komplekse u odnosu na prasad koja sisaju ZMK.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Relationship between growth of nursing pigs and composition of sow colostrum and milk from anterior and posterior mammary glands, Zavisnost rasta novorođene prasadi od sastava kolostruma i mleka prednjih odnosno zadnjih mamarnih kompleksa krmača",
volume = "63",
number = "5-6",
pages = "537-548",
doi = "10.2298/AVB1306537S"
}
Šamanc, H., Sladojević, Ž., Vujanac, I., Prodanović, R., Kirovski, M., Dodovski, P.,& Kirovski, D.. (2013). Relationship between growth of nursing pigs and composition of sow colostrum and milk from anterior and posterior mammary glands. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 63(5-6), 537-548.
https://doi.org/10.2298/AVB1306537S
Šamanc H, Sladojević Ž, Vujanac I, Prodanović R, Kirovski M, Dodovski P, Kirovski D. Relationship between growth of nursing pigs and composition of sow colostrum and milk from anterior and posterior mammary glands. in Acta Veterinaria-Beograd. 2013;63(5-6):537-548.
doi:10.2298/AVB1306537S .
Šamanc, Horea, Sladojević, Željko, Vujanac, Ivan, Prodanović, Radiša, Kirovski, M., Dodovski, Petar, Kirovski, Danijela, "Relationship between growth of nursing pigs and composition of sow colostrum and milk from anterior and posterior mammary glands" in Acta Veterinaria-Beograd, 63, no. 5-6 (2013):537-548,
https://doi.org/10.2298/AVB1306537S . .
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9
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Influence of housing conditions, number of farrowing and number of pigs in litter on weight loss in sows during lactation

Sladojević, Željko; Kasagić, D.; Kukolj, B.; Kirovski, Danijela

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2013)

TY  - JOUR
AU  - Sladojević, Željko
AU  - Kasagić, D.
AU  - Kukolj, B.
AU  - Kirovski, Danijela
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/951
AB  - The objective of this work was to investigate the influence of housing conditions, number of farrowing and number of pigs in litter on weight loss in sows during lactation. The experiment included 60 sows, half breed developed by cross breeding of Big Yorkshire and Swedish Landrace in lactation. Body weight of the sows (kg) was determined 2nd, 7th, 14th, 21st and 28th day after farrowing. On the basis of the obtained values, there was calculated the difference in body weight between two consecutive investigation periods. The sows were divided into two groups and held in different housing conditions: 30 of them were held in extensive, and other 30 sows in intensive way of farming. In regard to number of farrowing, the sows were divided into three groups: sows with one or two farrowing (group P1, n=20), with three or four farrowing (group P2, n=20), and sows that farrowed five or more times (P3,n=20). In regard to number of pigs in litter, the sows were divided into two groups: the first (Group I, n=30) with sows that had up to eight pigs, and the second (Group II, n=30) with sows that had nine or more pigs in litter. The obtained results showed that in all perids of the investigation during lactation, body weight in sows held in extensive farming conditions was statistically significantly higher compared to those from intensive farming conditions. On the other hand, the loss of body weight during lactation was significantly higher in sows from extensive in regard to intensive farming conditions in the first two weeks of lactation. The sows with bigger number of farrowing had greater body weight, compared to those with smaller number of farrowing. There was no statistically significant difference in body weight loss during lactation, between sows with different number of farrowing, but considering that the sows with less farrowings had significantly lower body weight, they consequently lost more weight in percentage. The sows with greater number of pigs had significantly smaller body weight in the end of lactation, that is on 21st and 28th day of lactation. The results of this investigation point out to the fact that mainly housing conditions, that is nutrition influence body weight loss, and after that comes the number of pigs in litter.
AB  - Cilj ovog rada je bio da se ispita uticaj različitih uslova držanja, pariteta i broja prasadi u leglu na gubitak telesne mase krmača u toku laktacije. U ogled je bilo uključeno 60 krmača meleza velikog jorkšira i švedskog landrasa u laktaciji. Telesna masa krmača (kg) je određena 2, 7, 14, 21. i 28. dana posle prašenja. Na osnovu dobijenih vrednosti, izračunata je razlika u telesnoj masi između dva uzastopna perioda ispitivanja. U odnosu na način držanja, krmače su podeljene u dve grupe od po trideset životinja: jedinke držane u ekstenzivnom načinu uzgoja i jedinke držane u intenzivnom načinu uzgoja. U odnosu na paritet, krmače su podijeljene u tri grupe: krmače sa jednim i dva prašenja (Grupa P1, n=20), krmače sa tri i četiri prašenja (Grupa P2, n=20) i krmače koje su se prasile pet i više puta (Grupa P3, n=20). U odnosu na broj prasadi u leglu, krmače su podeljene u dve grupe, prvu (Grupa I, n=30) koju su činile krmače sa do osam prasadi u leglu i drugu (Grupa II, n=30) koju su činile krmače sa devet i više prasadi u leglu. Dobijeni rezultati su pokazali da je u svim periodima ispitivanja tokom laktacije telesna masa krmača držanih u ekstenzivnom načinu uzgoja bila statistički značajno viša u odnosu na krmače iz intenzivnog načina držanja, dok je gubitak telesne mase tokom laktacije bio značajno veći kod krmača u ekstenzivnom, u odnosu na intenzivni uzgoj samo tokom prve dve nedelje laktacije. Krmače viših pariteta su imale značajno veću telesnu masu u odnosu na krmače nižih pariteta. Nije bilo statistič ki značajne razlike u gubitku telesne mase tokom laktacije između krmača različitih pariteta, ali uzimajući u obzir da su krmače nižih pariteta imale značajno nižu telesnu masu one su, izraženo procentualno u odnosu na njihovu telesnu masu, gubile više nego krmače viših pariteta. Krmače sa većim brojem prasadi su imale značajno manju telesnu masu, ali samo na kraju laktacije, odnosno 21. i 28. dana laktacije. Rezultati ovog istraživanja ukazuju da na gubitak telesne mase krmača u laktaciji prevashodno utiče način držanja, odnosno ishrana, a zatim i paritet i broj prasadi u leglu.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Influence of housing conditions, number of farrowing and number of pigs in litter on weight loss in sows during lactation
T1  - Uticaj različitih uslova držanja, pariteta i broja prasadi u leglu na gubitak telesne mase krmača u toku laktacije
VL  - 67
IS  - 5-6
SP  - 337
EP  - 348
DO  - 10.2298/VETGL1306337S
ER  - 
@article{
author = "Sladojević, Željko and Kasagić, D. and Kukolj, B. and Kirovski, Danijela",
year = "2013",
abstract = "The objective of this work was to investigate the influence of housing conditions, number of farrowing and number of pigs in litter on weight loss in sows during lactation. The experiment included 60 sows, half breed developed by cross breeding of Big Yorkshire and Swedish Landrace in lactation. Body weight of the sows (kg) was determined 2nd, 7th, 14th, 21st and 28th day after farrowing. On the basis of the obtained values, there was calculated the difference in body weight between two consecutive investigation periods. The sows were divided into two groups and held in different housing conditions: 30 of them were held in extensive, and other 30 sows in intensive way of farming. In regard to number of farrowing, the sows were divided into three groups: sows with one or two farrowing (group P1, n=20), with three or four farrowing (group P2, n=20), and sows that farrowed five or more times (P3,n=20). In regard to number of pigs in litter, the sows were divided into two groups: the first (Group I, n=30) with sows that had up to eight pigs, and the second (Group II, n=30) with sows that had nine or more pigs in litter. The obtained results showed that in all perids of the investigation during lactation, body weight in sows held in extensive farming conditions was statistically significantly higher compared to those from intensive farming conditions. On the other hand, the loss of body weight during lactation was significantly higher in sows from extensive in regard to intensive farming conditions in the first two weeks of lactation. The sows with bigger number of farrowing had greater body weight, compared to those with smaller number of farrowing. There was no statistically significant difference in body weight loss during lactation, between sows with different number of farrowing, but considering that the sows with less farrowings had significantly lower body weight, they consequently lost more weight in percentage. The sows with greater number of pigs had significantly smaller body weight in the end of lactation, that is on 21st and 28th day of lactation. The results of this investigation point out to the fact that mainly housing conditions, that is nutrition influence body weight loss, and after that comes the number of pigs in litter., Cilj ovog rada je bio da se ispita uticaj različitih uslova držanja, pariteta i broja prasadi u leglu na gubitak telesne mase krmača u toku laktacije. U ogled je bilo uključeno 60 krmača meleza velikog jorkšira i švedskog landrasa u laktaciji. Telesna masa krmača (kg) je određena 2, 7, 14, 21. i 28. dana posle prašenja. Na osnovu dobijenih vrednosti, izračunata je razlika u telesnoj masi između dva uzastopna perioda ispitivanja. U odnosu na način držanja, krmače su podeljene u dve grupe od po trideset životinja: jedinke držane u ekstenzivnom načinu uzgoja i jedinke držane u intenzivnom načinu uzgoja. U odnosu na paritet, krmače su podijeljene u tri grupe: krmače sa jednim i dva prašenja (Grupa P1, n=20), krmače sa tri i četiri prašenja (Grupa P2, n=20) i krmače koje su se prasile pet i više puta (Grupa P3, n=20). U odnosu na broj prasadi u leglu, krmače su podeljene u dve grupe, prvu (Grupa I, n=30) koju su činile krmače sa do osam prasadi u leglu i drugu (Grupa II, n=30) koju su činile krmače sa devet i više prasadi u leglu. Dobijeni rezultati su pokazali da je u svim periodima ispitivanja tokom laktacije telesna masa krmača držanih u ekstenzivnom načinu uzgoja bila statistički značajno viša u odnosu na krmače iz intenzivnog načina držanja, dok je gubitak telesne mase tokom laktacije bio značajno veći kod krmača u ekstenzivnom, u odnosu na intenzivni uzgoj samo tokom prve dve nedelje laktacije. Krmače viših pariteta su imale značajno veću telesnu masu u odnosu na krmače nižih pariteta. Nije bilo statistič ki značajne razlike u gubitku telesne mase tokom laktacije između krmača različitih pariteta, ali uzimajući u obzir da su krmače nižih pariteta imale značajno nižu telesnu masu one su, izraženo procentualno u odnosu na njihovu telesnu masu, gubile više nego krmače viših pariteta. Krmače sa većim brojem prasadi su imale značajno manju telesnu masu, ali samo na kraju laktacije, odnosno 21. i 28. dana laktacije. Rezultati ovog istraživanja ukazuju da na gubitak telesne mase krmača u laktaciji prevashodno utiče način držanja, odnosno ishrana, a zatim i paritet i broj prasadi u leglu.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Influence of housing conditions, number of farrowing and number of pigs in litter on weight loss in sows during lactation, Uticaj različitih uslova držanja, pariteta i broja prasadi u leglu na gubitak telesne mase krmača u toku laktacije",
volume = "67",
number = "5-6",
pages = "337-348",
doi = "10.2298/VETGL1306337S"
}
Sladojević, Ž., Kasagić, D., Kukolj, B.,& Kirovski, D.. (2013). Influence of housing conditions, number of farrowing and number of pigs in litter on weight loss in sows during lactation. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 67(5-6), 337-348.
https://doi.org/10.2298/VETGL1306337S
Sladojević Ž, Kasagić D, Kukolj B, Kirovski D. Influence of housing conditions, number of farrowing and number of pigs in litter on weight loss in sows during lactation. in Veterinarski Glasnik. 2013;67(5-6):337-348.
doi:10.2298/VETGL1306337S .
Sladojević, Željko, Kasagić, D., Kukolj, B., Kirovski, Danijela, "Influence of housing conditions, number of farrowing and number of pigs in litter on weight loss in sows during lactation" in Veterinarski Glasnik, 67, no. 5-6 (2013):337-348,
https://doi.org/10.2298/VETGL1306337S . .

Effect of peripartum dietary energy supplementation on thyroid hormones, insulin-like growth factor-i and its binding proteins in early lactation dairy cows

Kirovski, Danijela; Sladojević, Željko; Stojić, Velibor; Vujanac, Ivan; Lazarević, Miodrag; Radovanović, Anita; Savić, Đ.; Nedić, Olgica

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2012)

TY  - JOUR
AU  - Kirovski, Danijela
AU  - Sladojević, Željko
AU  - Stojić, Velibor
AU  - Vujanac, Ivan
AU  - Lazarević, Miodrag
AU  - Radovanović, Anita
AU  - Savić, Đ.
AU  - Nedić, Olgica
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/860
AB  - The objective of this study was to examine the effect of dietary energy supplementation on hormones that are considered to be the main signals of a shift in energy balance around parturition. Sixty dry cows, 15 days before calving, were chosen and divided into two eaqual groups: control and experimental (GLY). Both groups were fed a standard ration balanced in accordance to the stage of the productive reproductive cycle. Additionally, each cow in the GLY group was given glycerol based dietary energy supplementation (250 mL daily during the dry and 300 mL daily during the lactation period), which provided additional 9.30 MJ NEL during the dry and 13.95 MJ NEL during the early lactation period. Milk production was measured on days 30 and 60 of lactation and milk production was significantly higher in GLY compared to control group at day 60 of lactation (p lt 0.05). Service period and insemination index were used as reproductive outcome parameters. Average service period in the control group was significantly longer than in the GLY group (p lt 0.05). Average insemination index in the control group was not significantly different than the index obtained for the GLY group. Blood samples were taken before the begining of the experiment (15 days before parturition), and at days 7, 30 and 60 of lactation. Concentrations of thyroid hormones, IGF-I, relative abundance of IGFBP-2, IGFBP-3 and IGFBP-4, concentrations of total protein and albumin in the blood were measured. Results showed that at days 7 and 30 after parturition, T4 concentrations were significantly higher (p lt 0.001, respectively) in GLY than in the control group, while T3 concentrations were significantly higher in GLY group only at day 7 after parturition (p lt 0.001). IGF-I concentrations and IGFBP-3 abundance were significantly higher in the GLY compared to the control group in all three examined postpartum periods. IGFBP-2 and IGFBP-4 concentrations were higher in GLY compared to the control group in all three examined postpartum periods, but the difference was significant only on day 60 after parturition (p lt 0.01, respectively). Concentrations of total protein and albumin were significantly higher in GLY compared to the control group in all three examined periods after parturition. Based on these results it can be concluded that peripartum dietary energy supplementation prevent cows' exposure to severe negative energy balance, preserves synthetic activity of hepatocytes and consequently has a positive impact on milk production and reproductive performances in dairy cows.
AB  - Cilj ovog rada je bio da se ispita uticaj energetskog dodatka u ishrani krava na koncentraciju hormona u krvi koji su u periodu oko teljenja glavni pokazatelji promena u energetskom statusu. U tu svrhu, petnaest dana pre teljenja odabrano je 60 krava koje su podeljene u dve jednake grupe: kontrolnu i oglednu (GLY). Obe grupe krava su dobijale identičan obrok usklađen sa proizvodno reproduktivnim ciklusom. Dodatno, kravama GLY grupe je tokom poslednje dve nedelje zasušenja i do 60. dana laktacije dodavan energetski dodatak na bazi glicerola (250 mL dnevno tokom zasušenja odnosno 300 mL nakon teljenja), obezbeđujući dodatnih 9,30 MJ NEL tokom zasušenja, odnosno 13,95 MJ NEL tokom rane laktacije. Kod svih krava je izmerena prosečna dnevna proizvodnja mleka 30. i 60. dana lakatcije, koja je kod GLY grupe bila značajno viša 60. dana (p lt 0,05). Kao pokazatelji reproduktivnog statusa koriščeni su servis period i indeks osemenjavanja. Servis period je bio značajno duži kod kontrolne u odnosu na GLY grupu (p lt 0,05), a vrednost indeksa osemenjavanja se nije značajno razlikovala između grupa. Uzorci krvi krava uzeti su neposredno pre početka ogleda, odnosno 15 dana pre teljenja, kao i 7, 30. i 60. dana laktacije i u njima je određivana koncentracija tireoidnih hormona, IGF-I, relativna zastupljenost IGFBP-2, IGFBP-3 i IGFBP-4, koncentracija ukupnih proteina i albumina. Rezultati su ukazali da je 7. i 30. dana nakon teljenja GLY grupa imala značajno višu koncentraciju T4 (p lt 0,001, pojedinačno) u odnosu na kontrolu, dok je koncentarcija T3 bila značajno viša kod GLY grupe 7. dana nakon teljenja (p lt 0,001). Koncentracija IGF-I i zastupljenost IGFBP-3 je bila značajno viša u krvi krava GLY grupe u odnosu na kontrolu u sva tri ispitivana perioda posle teljenja. Zastupljenost IGFBP-2 i IGFBP-4 je bila viša u krvi krava GLY u odnosu na kontrolnu grupu u sva tri ispitivana perioda postapartalno ali je ova razlika bila značajna jedino 60. dana lakatcije (p lt 0.01, pojedinačno). Koncentracija ukupnih proteina i albumina je, takođe, bila značajno viša u krvi krava GLY grupe u odnosu na kontrolnu grupu u sva tri ispitivana perioda posle teljenja. Na osnovu dobijenih rezultata može se zaključiti da energetski dodatak u ishrani sprečava izloženost krava izrazitom negativnom energetskom bilansu, održava sintetsku funkciju hepatocita i posledično ima pozitivan uticaj na mlečnost i reproduktivne pokazatelje.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Effect of peripartum dietary energy supplementation on thyroid hormones, insulin-like growth factor-i and its binding proteins in early lactation dairy cows
T1  - Uticaj energetskog dodatka u ishrani na koncentraciju tireoidnih hormona, insulinu sličnog faktora rasta-i i njegovih vezujućih proteina u krvi krava tokom rane laktacije
VL  - 62
IS  - 4
SP  - 403
EP  - 419
DO  - 10.2298/AVB1204403K
ER  - 
@article{
author = "Kirovski, Danijela and Sladojević, Željko and Stojić, Velibor and Vujanac, Ivan and Lazarević, Miodrag and Radovanović, Anita and Savić, Đ. and Nedić, Olgica",
year = "2012",
abstract = "The objective of this study was to examine the effect of dietary energy supplementation on hormones that are considered to be the main signals of a shift in energy balance around parturition. Sixty dry cows, 15 days before calving, were chosen and divided into two eaqual groups: control and experimental (GLY). Both groups were fed a standard ration balanced in accordance to the stage of the productive reproductive cycle. Additionally, each cow in the GLY group was given glycerol based dietary energy supplementation (250 mL daily during the dry and 300 mL daily during the lactation period), which provided additional 9.30 MJ NEL during the dry and 13.95 MJ NEL during the early lactation period. Milk production was measured on days 30 and 60 of lactation and milk production was significantly higher in GLY compared to control group at day 60 of lactation (p lt 0.05). Service period and insemination index were used as reproductive outcome parameters. Average service period in the control group was significantly longer than in the GLY group (p lt 0.05). Average insemination index in the control group was not significantly different than the index obtained for the GLY group. Blood samples were taken before the begining of the experiment (15 days before parturition), and at days 7, 30 and 60 of lactation. Concentrations of thyroid hormones, IGF-I, relative abundance of IGFBP-2, IGFBP-3 and IGFBP-4, concentrations of total protein and albumin in the blood were measured. Results showed that at days 7 and 30 after parturition, T4 concentrations were significantly higher (p lt 0.001, respectively) in GLY than in the control group, while T3 concentrations were significantly higher in GLY group only at day 7 after parturition (p lt 0.001). IGF-I concentrations and IGFBP-3 abundance were significantly higher in the GLY compared to the control group in all three examined postpartum periods. IGFBP-2 and IGFBP-4 concentrations were higher in GLY compared to the control group in all three examined postpartum periods, but the difference was significant only on day 60 after parturition (p lt 0.01, respectively). Concentrations of total protein and albumin were significantly higher in GLY compared to the control group in all three examined periods after parturition. Based on these results it can be concluded that peripartum dietary energy supplementation prevent cows' exposure to severe negative energy balance, preserves synthetic activity of hepatocytes and consequently has a positive impact on milk production and reproductive performances in dairy cows., Cilj ovog rada je bio da se ispita uticaj energetskog dodatka u ishrani krava na koncentraciju hormona u krvi koji su u periodu oko teljenja glavni pokazatelji promena u energetskom statusu. U tu svrhu, petnaest dana pre teljenja odabrano je 60 krava koje su podeljene u dve jednake grupe: kontrolnu i oglednu (GLY). Obe grupe krava su dobijale identičan obrok usklađen sa proizvodno reproduktivnim ciklusom. Dodatno, kravama GLY grupe je tokom poslednje dve nedelje zasušenja i do 60. dana laktacije dodavan energetski dodatak na bazi glicerola (250 mL dnevno tokom zasušenja odnosno 300 mL nakon teljenja), obezbeđujući dodatnih 9,30 MJ NEL tokom zasušenja, odnosno 13,95 MJ NEL tokom rane laktacije. Kod svih krava je izmerena prosečna dnevna proizvodnja mleka 30. i 60. dana lakatcije, koja je kod GLY grupe bila značajno viša 60. dana (p lt 0,05). Kao pokazatelji reproduktivnog statusa koriščeni su servis period i indeks osemenjavanja. Servis period je bio značajno duži kod kontrolne u odnosu na GLY grupu (p lt 0,05), a vrednost indeksa osemenjavanja se nije značajno razlikovala između grupa. Uzorci krvi krava uzeti su neposredno pre početka ogleda, odnosno 15 dana pre teljenja, kao i 7, 30. i 60. dana laktacije i u njima je određivana koncentracija tireoidnih hormona, IGF-I, relativna zastupljenost IGFBP-2, IGFBP-3 i IGFBP-4, koncentracija ukupnih proteina i albumina. Rezultati su ukazali da je 7. i 30. dana nakon teljenja GLY grupa imala značajno višu koncentraciju T4 (p lt 0,001, pojedinačno) u odnosu na kontrolu, dok je koncentarcija T3 bila značajno viša kod GLY grupe 7. dana nakon teljenja (p lt 0,001). Koncentracija IGF-I i zastupljenost IGFBP-3 je bila značajno viša u krvi krava GLY grupe u odnosu na kontrolu u sva tri ispitivana perioda posle teljenja. Zastupljenost IGFBP-2 i IGFBP-4 je bila viša u krvi krava GLY u odnosu na kontrolnu grupu u sva tri ispitivana perioda postapartalno ali je ova razlika bila značajna jedino 60. dana lakatcije (p lt 0.01, pojedinačno). Koncentracija ukupnih proteina i albumina je, takođe, bila značajno viša u krvi krava GLY grupe u odnosu na kontrolnu grupu u sva tri ispitivana perioda posle teljenja. Na osnovu dobijenih rezultata može se zaključiti da energetski dodatak u ishrani sprečava izloženost krava izrazitom negativnom energetskom bilansu, održava sintetsku funkciju hepatocita i posledično ima pozitivan uticaj na mlečnost i reproduktivne pokazatelje.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Effect of peripartum dietary energy supplementation on thyroid hormones, insulin-like growth factor-i and its binding proteins in early lactation dairy cows, Uticaj energetskog dodatka u ishrani na koncentraciju tireoidnih hormona, insulinu sličnog faktora rasta-i i njegovih vezujućih proteina u krvi krava tokom rane laktacije",
volume = "62",
number = "4",
pages = "403-419",
doi = "10.2298/AVB1204403K"
}
Kirovski, D., Sladojević, Ž., Stojić, V., Vujanac, I., Lazarević, M., Radovanović, A., Savić, Đ.,& Nedić, O.. (2012). Effect of peripartum dietary energy supplementation on thyroid hormones, insulin-like growth factor-i and its binding proteins in early lactation dairy cows. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 62(4), 403-419.
https://doi.org/10.2298/AVB1204403K
Kirovski D, Sladojević Ž, Stojić V, Vujanac I, Lazarević M, Radovanović A, Savić Đ, Nedić O. Effect of peripartum dietary energy supplementation on thyroid hormones, insulin-like growth factor-i and its binding proteins in early lactation dairy cows. in Acta Veterinaria-Beograd. 2012;62(4):403-419.
doi:10.2298/AVB1204403K .
Kirovski, Danijela, Sladojević, Željko, Stojić, Velibor, Vujanac, Ivan, Lazarević, Miodrag, Radovanović, Anita, Savić, Đ., Nedić, Olgica, "Effect of peripartum dietary energy supplementation on thyroid hormones, insulin-like growth factor-i and its binding proteins in early lactation dairy cows" in Acta Veterinaria-Beograd, 62, no. 4 (2012):403-419,
https://doi.org/10.2298/AVB1204403K . .
3
1
4

Use of metabolic profiles and body condition scoring for the assessment of energy status of dairy cows

Prodanović, Radiša; Sladojević, Željko; Kirovski, Danijela; Vujanac, Ivan; Ivetić, V.; Savić, Božidar; Kureljušić, Branislav; Stevančević, M.

(Institut za stočarstvo, Beograd, 2012)

TY  - JOUR
AU  - Prodanović, Radiša
AU  - Sladojević, Željko
AU  - Kirovski, Danijela
AU  - Vujanac, Ivan
AU  - Ivetić, V.
AU  - Savić, Božidar
AU  - Kureljušić, Branislav
AU  - Stevančević, M.
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/906
AB  - The aim of this study was to assess the significance of body condition scoring and metabolic profile test for estimation of energy status of healthy high-yielding dairy cows. Twenty one healthy cows (primiparous and secundiparous) were divided into three groups: dry cows, early puerperal cows and early lactating cows. Cow's energy status was estimated by the analysis of blood samples for beta-hydroxybutirate (BHBA) and glucose. Additionally, urea, total bilirubine and total protein were measured in blood serum samples. According to body condition scores (BCS) results dry cows were overweight (4.03±0.29 points). Immediately after calving, cows lost their weight significantly, since BCS was 2.85±0.46 points at puerperal period and 3.12±0.33 points at day 60 of lactation (p lt 0.001 compared to dry period, respectively). Glucose concentration did not change significantly between dry and puerperal period, while BHBA increased significantly (0.46±0.14 mmol/l at dry period to 1.08±0.21 mmol/l at puerperal period; p lt 0.001). Urea concentration did not change significantly during examined period. Total bilirubin concentration significantly increased from dry (6.31±0.37 mmol/l) to puerperal period (7.63±2.52 mmol/l; p lt 0.001 compared to dry period) and remained high until day 60 of lactation (7.62±0.13 mmol/l; p lt 0.001 compared to dry period). Total protein concentration decreased from dry to puerperal period (69.59±6.14 g/l to 58.87±3.29 g/l; p lt 0.001). According to obtained results it can be concluded that cows were not in adequate energy status during transition period. Our results also indicate that, body condition scoring, BHBA and total bilirubin concentrations can be used as reliable indicators of cow's energy status even when there are not clinically visible health disorders.
AB  - Cilj istraživanja bio je da se ukaže na značaj metaboličkog profila i telesne kondicije u oceni energetskog statusa visoko-mlečnih krava holštajn rase. Za ispitivanje su odabrane tri grupe po sedam krava. Uzorci krvi uzimani su u zasušenju (15 dana pre očekivanog teljenja), ranom puerperijumu (7 dana nakon teljenja) i 60. dana laktacije. U uzorcima sveže krvi određivana je koncentracija glukoze i beta hidroksi-buterne kiseline (BHBA), a u uzorcima krvnog seruma koncentracija ukupnih proteina, ureje i ukupnog bilirubina. Rezultati ocene telesne kondicije pokazuju da su krave u periodu zasušenja preuhranjene (X=4,03±0,29 poena), dok su u puerperijumu (X=2,85±0,46 poena) i 60. dana laktacije (X=3,12±0,33 poena) u značajno slabijoj telesnoj kondiciji (p lt 0,001 u odnosu na zasušenje). Rezultati ispitivanja parametara metaboličkog profila ukazuju da je koncentracija proteina jedino u periodu ranog puerperijuma bila niža od fiziološke vrednosti (X=56,87±3,29 g/l). Koncentracija glukoze nije se statistički značajno menjala tokom ispitivanih perioda, dok je neposredno posle teljenja došlo do značajnog povećanja koncentracije BHBA (p lt 0,001 u odnosu na zasušenje). Uremija u periodu zasušenja (X=7,73±2,34 mmol/l), ranom puerperijumu (X=8,07±3,09 mmol/l) i 60. dana laktacije (X=7,41±2,03 mmol/l) bila je veća od gornje fiziološke granice. Koncentracija ukupnog bilirubina u periodu zasušenja je bila značajno niža (p lt 0,001) u odnosu na oba ispitivana perioda nakon teljenja. Na osnovu dobijenih rezultata može se zaključiti da krave nisu adekvatno pripremljene za nastupajuću laktaciju, zbog čega je kod njih došlo do značajnog odstupanja u telesnoj kondiciji i vrednostima parametara metaboličkog profila. Ova odstupanja ukazuju na nedovoljnu sposobnost životinja da se prilagode u uslovima negativnog bilansa energije na početku laktacije.
PB  - Institut za stočarstvo, Beograd
T2  - Biotechnology in Animal Husbandry
T1  - Use of metabolic profiles and body condition scoring for the assessment of energy status of dairy cows
T1  - Procena energetskog statusa krava na osnovu telesne kondicije i parametara metaboličkog profila
VL  - 28
IS  - 1
SP  - 25
EP  - 32
DO  - 10.2298/BAH1201025P
ER  - 
@article{
author = "Prodanović, Radiša and Sladojević, Željko and Kirovski, Danijela and Vujanac, Ivan and Ivetić, V. and Savić, Božidar and Kureljušić, Branislav and Stevančević, M.",
year = "2012",
abstract = "The aim of this study was to assess the significance of body condition scoring and metabolic profile test for estimation of energy status of healthy high-yielding dairy cows. Twenty one healthy cows (primiparous and secundiparous) were divided into three groups: dry cows, early puerperal cows and early lactating cows. Cow's energy status was estimated by the analysis of blood samples for beta-hydroxybutirate (BHBA) and glucose. Additionally, urea, total bilirubine and total protein were measured in blood serum samples. According to body condition scores (BCS) results dry cows were overweight (4.03±0.29 points). Immediately after calving, cows lost their weight significantly, since BCS was 2.85±0.46 points at puerperal period and 3.12±0.33 points at day 60 of lactation (p lt 0.001 compared to dry period, respectively). Glucose concentration did not change significantly between dry and puerperal period, while BHBA increased significantly (0.46±0.14 mmol/l at dry period to 1.08±0.21 mmol/l at puerperal period; p lt 0.001). Urea concentration did not change significantly during examined period. Total bilirubin concentration significantly increased from dry (6.31±0.37 mmol/l) to puerperal period (7.63±2.52 mmol/l; p lt 0.001 compared to dry period) and remained high until day 60 of lactation (7.62±0.13 mmol/l; p lt 0.001 compared to dry period). Total protein concentration decreased from dry to puerperal period (69.59±6.14 g/l to 58.87±3.29 g/l; p lt 0.001). According to obtained results it can be concluded that cows were not in adequate energy status during transition period. Our results also indicate that, body condition scoring, BHBA and total bilirubin concentrations can be used as reliable indicators of cow's energy status even when there are not clinically visible health disorders., Cilj istraživanja bio je da se ukaže na značaj metaboličkog profila i telesne kondicije u oceni energetskog statusa visoko-mlečnih krava holštajn rase. Za ispitivanje su odabrane tri grupe po sedam krava. Uzorci krvi uzimani su u zasušenju (15 dana pre očekivanog teljenja), ranom puerperijumu (7 dana nakon teljenja) i 60. dana laktacije. U uzorcima sveže krvi određivana je koncentracija glukoze i beta hidroksi-buterne kiseline (BHBA), a u uzorcima krvnog seruma koncentracija ukupnih proteina, ureje i ukupnog bilirubina. Rezultati ocene telesne kondicije pokazuju da su krave u periodu zasušenja preuhranjene (X=4,03±0,29 poena), dok su u puerperijumu (X=2,85±0,46 poena) i 60. dana laktacije (X=3,12±0,33 poena) u značajno slabijoj telesnoj kondiciji (p lt 0,001 u odnosu na zasušenje). Rezultati ispitivanja parametara metaboličkog profila ukazuju da je koncentracija proteina jedino u periodu ranog puerperijuma bila niža od fiziološke vrednosti (X=56,87±3,29 g/l). Koncentracija glukoze nije se statistički značajno menjala tokom ispitivanih perioda, dok je neposredno posle teljenja došlo do značajnog povećanja koncentracije BHBA (p lt 0,001 u odnosu na zasušenje). Uremija u periodu zasušenja (X=7,73±2,34 mmol/l), ranom puerperijumu (X=8,07±3,09 mmol/l) i 60. dana laktacije (X=7,41±2,03 mmol/l) bila je veća od gornje fiziološke granice. Koncentracija ukupnog bilirubina u periodu zasušenja je bila značajno niža (p lt 0,001) u odnosu na oba ispitivana perioda nakon teljenja. Na osnovu dobijenih rezultata može se zaključiti da krave nisu adekvatno pripremljene za nastupajuću laktaciju, zbog čega je kod njih došlo do značajnog odstupanja u telesnoj kondiciji i vrednostima parametara metaboličkog profila. Ova odstupanja ukazuju na nedovoljnu sposobnost životinja da se prilagode u uslovima negativnog bilansa energije na početku laktacije.",
publisher = "Institut za stočarstvo, Beograd",
journal = "Biotechnology in Animal Husbandry",
title = "Use of metabolic profiles and body condition scoring for the assessment of energy status of dairy cows, Procena energetskog statusa krava na osnovu telesne kondicije i parametara metaboličkog profila",
volume = "28",
number = "1",
pages = "25-32",
doi = "10.2298/BAH1201025P"
}
Prodanović, R., Sladojević, Ž., Kirovski, D., Vujanac, I., Ivetić, V., Savić, B., Kureljušić, B.,& Stevančević, M.. (2012). Use of metabolic profiles and body condition scoring for the assessment of energy status of dairy cows. in Biotechnology in Animal Husbandry
Institut za stočarstvo, Beograd., 28(1), 25-32.
https://doi.org/10.2298/BAH1201025P
Prodanović R, Sladojević Ž, Kirovski D, Vujanac I, Ivetić V, Savić B, Kureljušić B, Stevančević M. Use of metabolic profiles and body condition scoring for the assessment of energy status of dairy cows. in Biotechnology in Animal Husbandry. 2012;28(1):25-32.
doi:10.2298/BAH1201025P .
Prodanović, Radiša, Sladojević, Željko, Kirovski, Danijela, Vujanac, Ivan, Ivetić, V., Savić, Božidar, Kureljušić, Branislav, Stevančević, M., "Use of metabolic profiles and body condition scoring for the assessment of energy status of dairy cows" in Biotechnology in Animal Husbandry, 28, no. 1 (2012):25-32,
https://doi.org/10.2298/BAH1201025P . .
4

Concentration of cortisol, insulin-like growth factor-I and immunoglobulin G class in blood of neonatal calves of different body mass at birth

Kirovski, Danijela; Šamanc, Horea; Fratrić, Natalija; Gvozdić, Dragan; Hristov, Slavča; Sladojević, Željko; Mircu, Calin; Tulcan, Camelia

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2009)

TY  - JOUR
AU  - Kirovski, Danijela
AU  - Šamanc, Horea
AU  - Fratrić, Natalija
AU  - Gvozdić, Dragan
AU  - Hristov, Slavča
AU  - Sladojević, Željko
AU  - Mircu, Calin
AU  - Tulcan, Camelia
PY  - 2009
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/586
AB  - The objective of this work was to examine whether concentrations of cortisol, insulin-like growth factor-I (IGF-I) and immunoglobulin G class (IgG), in fact blood parameters which are believed to be of extreme importance in the postnatal survival of calves, are dependant on the body mass of calves at birth. Investigations were performed on 12 newborn calves of the Holstein-Friesian breed, placed into two groups on the grounds of their body mass at birth. The first group (n=6) comprised calves whose body mass was more than 35 kg at birth (41.67±3.08 kg), while the second group (n=6) comprised calves whose body mass at birth was less than 35 kg (32.00±3.58 kg). Blood samples were taken immediately preceding the consuming of colostrum, as well as at 32 hours of neonatal life. Cortisol and IGF-I concentrations were determined in blood serum samples taken immediately before colostrum consumption, while IgG concentration was determined in the samples taken 32 hours after the birth of the calves. The cortisol concentration in calves born with a greater body mass (61.51±32.78 nmol/l) was lower (p=0.052) than in calves born with a smaller body mass (94.89±17.74 nmol/l). A significant negative correlation (r= -0.592; p lt 0.05) was established between the body mass of calves at birth and the cortisol concentration. The IGF-I concentration determined immediately following birth in calves with a greater boy mass at birth (10.17±1.71 nmol/l) was statistically significantly higher (p lt 0.05) in comparison with calves born with a smaller body mass (7.04±1.15 nmol/l). There was a significant positive correlation (r = 0.519; p lt 0.10) between the body mass of calves at birth and the IGF-I concentration. Thirty-two hours following birth, the IgG concentration in blood serum of calves born with a bigger body mass (18.72±1.99 g/l) was significantly higher (p lt 0.05) than in calves born with a smaller body mass (11.68±4.79 g/l). A significant positive correlation was established between the body mass of calves at birth and the IgG concentration determined at 32 hours of neonatal life (r = 0.620; p lt 0.05). The obtained results point to the conclusion that calves of body mass over 35 kg at birth are better adapted to the conditions of the outer environment in comparison with calves born with a body mass of less than 35 kg. .
AB  - Cilj ovog rada je da se ispita da li koncentracije kortizola, insulinusličnog faktora rasta-I (IGF-I) i imunoglobulina klase G (IgG), odnosno parametara krvi za koje se smatra da su izuzetno značajni za postnatalni opstanak teladi, zavise od telesne mase teladi na rođenju. Ispitivanja su izvršena na 12 novorođenih teladi Holštajn-Frizijske rase, razdvojenih u dve grupe na osnovu telesne mase na rođenju. U prvu grupu (n=6) svrstana su telad čija je telesna masa bila veća od 35 kg na rođenju (41,67±3,08 kg), dok su u drugu grupu (n=6) svrstana telad čija je telesna masa na rođenju bila manja od 35 kg (32,00±3,58kg). Neposredno pre napajanja kolostrumom, kao i 32. sata neonatalnog života, uzeti su uzorci krvi. U uzorcima krvnog seruma uzetim neposredno pre napajanja kolostrumom određivana je koncentracija kortizola i IGF-I, dok je u uzorcima uzetim 32 sata nakon rođenja teladi određivana koncentracija IgG. Koncentracija kortizola kod teladi rođene sa većom telesnom masom (61,51±32,78 nmol/l) je bila niža (p= 0,052) nego kod teladi rođenih sa nižom telesnom masom (94,89± 17,74 nmol/l). Utvrđena je značajna negativna korelacija (r=-0,592; p lt 0,05) između telesne mase teladi na rođenju i koncentracije kortizola. Koncentracija IGF-I određena neposredno nakon rođenja kod teladi sa većom telesnom masom na rođenju (10,17±1,71 nmol/l) bila je statistički značajno veća (p lt 0,05) u odnosu na telad rođenu sa nižom telesnom masom (7,04±1,15 nmol/l). Postojala je značajna pozitivna korelacija (r=0,519; p lt 0,10), između telesne mase teladi na rođenju i koncentracije IGF-I. Trideset dva sata nakon rođenja koncentracija IgG u krvnom serumu teladi rođene sa višom telesnom masom (18,72± 1,99 g/l) je bila značajno viša (p lt 0,05) nego kod teladi rođene sa nižom telesnom masom (11,68±4,79 g/l). Utvrđena je značajna pozitivna korelacija između telesne mase teladi na rođenju i koncentracije IgG određene trideset i drugog sata neonatalnog života (r=0,620; p lt 0,05). Dobijeni rezultati upućuju na zaključak da su telad telesne mase preko 35 kg na rođenju bolje adaptirana na uslove spoljašnje sredine u odnosu na telad koja su rođena sa telesnom masom manjom od 35 kilograma. .
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Concentration of cortisol, insulin-like growth factor-I and immunoglobulin G class in blood of neonatal calves of different body mass at birth
T1  - Koncentracija kortizola, insulinu sličnog faktora rasta-I i imunoglobulina G-klase u krvi neonatalne teladi različite telesne mase na rođenju
VL  - 63
IS  - 5-6
SP  - 321
EP  - 329
DO  - 10.2298/VETGL0906321K
ER  - 
@article{
author = "Kirovski, Danijela and Šamanc, Horea and Fratrić, Natalija and Gvozdić, Dragan and Hristov, Slavča and Sladojević, Željko and Mircu, Calin and Tulcan, Camelia",
year = "2009",
abstract = "The objective of this work was to examine whether concentrations of cortisol, insulin-like growth factor-I (IGF-I) and immunoglobulin G class (IgG), in fact blood parameters which are believed to be of extreme importance in the postnatal survival of calves, are dependant on the body mass of calves at birth. Investigations were performed on 12 newborn calves of the Holstein-Friesian breed, placed into two groups on the grounds of their body mass at birth. The first group (n=6) comprised calves whose body mass was more than 35 kg at birth (41.67±3.08 kg), while the second group (n=6) comprised calves whose body mass at birth was less than 35 kg (32.00±3.58 kg). Blood samples were taken immediately preceding the consuming of colostrum, as well as at 32 hours of neonatal life. Cortisol and IGF-I concentrations were determined in blood serum samples taken immediately before colostrum consumption, while IgG concentration was determined in the samples taken 32 hours after the birth of the calves. The cortisol concentration in calves born with a greater body mass (61.51±32.78 nmol/l) was lower (p=0.052) than in calves born with a smaller body mass (94.89±17.74 nmol/l). A significant negative correlation (r= -0.592; p lt 0.05) was established between the body mass of calves at birth and the cortisol concentration. The IGF-I concentration determined immediately following birth in calves with a greater boy mass at birth (10.17±1.71 nmol/l) was statistically significantly higher (p lt 0.05) in comparison with calves born with a smaller body mass (7.04±1.15 nmol/l). There was a significant positive correlation (r = 0.519; p lt 0.10) between the body mass of calves at birth and the IGF-I concentration. Thirty-two hours following birth, the IgG concentration in blood serum of calves born with a bigger body mass (18.72±1.99 g/l) was significantly higher (p lt 0.05) than in calves born with a smaller body mass (11.68±4.79 g/l). A significant positive correlation was established between the body mass of calves at birth and the IgG concentration determined at 32 hours of neonatal life (r = 0.620; p lt 0.05). The obtained results point to the conclusion that calves of body mass over 35 kg at birth are better adapted to the conditions of the outer environment in comparison with calves born with a body mass of less than 35 kg. ., Cilj ovog rada je da se ispita da li koncentracije kortizola, insulinusličnog faktora rasta-I (IGF-I) i imunoglobulina klase G (IgG), odnosno parametara krvi za koje se smatra da su izuzetno značajni za postnatalni opstanak teladi, zavise od telesne mase teladi na rođenju. Ispitivanja su izvršena na 12 novorođenih teladi Holštajn-Frizijske rase, razdvojenih u dve grupe na osnovu telesne mase na rođenju. U prvu grupu (n=6) svrstana su telad čija je telesna masa bila veća od 35 kg na rođenju (41,67±3,08 kg), dok su u drugu grupu (n=6) svrstana telad čija je telesna masa na rođenju bila manja od 35 kg (32,00±3,58kg). Neposredno pre napajanja kolostrumom, kao i 32. sata neonatalnog života, uzeti su uzorci krvi. U uzorcima krvnog seruma uzetim neposredno pre napajanja kolostrumom određivana je koncentracija kortizola i IGF-I, dok je u uzorcima uzetim 32 sata nakon rođenja teladi određivana koncentracija IgG. Koncentracija kortizola kod teladi rođene sa većom telesnom masom (61,51±32,78 nmol/l) je bila niža (p= 0,052) nego kod teladi rođenih sa nižom telesnom masom (94,89± 17,74 nmol/l). Utvrđena je značajna negativna korelacija (r=-0,592; p lt 0,05) između telesne mase teladi na rođenju i koncentracije kortizola. Koncentracija IGF-I određena neposredno nakon rođenja kod teladi sa većom telesnom masom na rođenju (10,17±1,71 nmol/l) bila je statistički značajno veća (p lt 0,05) u odnosu na telad rođenu sa nižom telesnom masom (7,04±1,15 nmol/l). Postojala je značajna pozitivna korelacija (r=0,519; p lt 0,10), između telesne mase teladi na rođenju i koncentracije IGF-I. Trideset dva sata nakon rođenja koncentracija IgG u krvnom serumu teladi rođene sa višom telesnom masom (18,72± 1,99 g/l) je bila značajno viša (p lt 0,05) nego kod teladi rođene sa nižom telesnom masom (11,68±4,79 g/l). Utvrđena je značajna pozitivna korelacija između telesne mase teladi na rođenju i koncentracije IgG određene trideset i drugog sata neonatalnog života (r=0,620; p lt 0,05). Dobijeni rezultati upućuju na zaključak da su telad telesne mase preko 35 kg na rođenju bolje adaptirana na uslove spoljašnje sredine u odnosu na telad koja su rođena sa telesnom masom manjom od 35 kilograma. .",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Concentration of cortisol, insulin-like growth factor-I and immunoglobulin G class in blood of neonatal calves of different body mass at birth, Koncentracija kortizola, insulinu sličnog faktora rasta-I i imunoglobulina G-klase u krvi neonatalne teladi različite telesne mase na rođenju",
volume = "63",
number = "5-6",
pages = "321-329",
doi = "10.2298/VETGL0906321K"
}
Kirovski, D., Šamanc, H., Fratrić, N., Gvozdić, D., Hristov, S., Sladojević, Ž., Mircu, C.,& Tulcan, C.. (2009). Concentration of cortisol, insulin-like growth factor-I and immunoglobulin G class in blood of neonatal calves of different body mass at birth. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 63(5-6), 321-329.
https://doi.org/10.2298/VETGL0906321K
Kirovski D, Šamanc H, Fratrić N, Gvozdić D, Hristov S, Sladojević Ž, Mircu C, Tulcan C. Concentration of cortisol, insulin-like growth factor-I and immunoglobulin G class in blood of neonatal calves of different body mass at birth. in Veterinarski Glasnik. 2009;63(5-6):321-329.
doi:10.2298/VETGL0906321K .
Kirovski, Danijela, Šamanc, Horea, Fratrić, Natalija, Gvozdić, Dragan, Hristov, Slavča, Sladojević, Željko, Mircu, Calin, Tulcan, Camelia, "Concentration of cortisol, insulin-like growth factor-I and immunoglobulin G class in blood of neonatal calves of different body mass at birth" in Veterinarski Glasnik, 63, no. 5-6 (2009):321-329,
https://doi.org/10.2298/VETGL0906321K . .

Blood concentration of proteins, bilirubin and glucose in cows with left displaced abomasum

Šamanc, Horea; Kirovski, Danijela; Prodanović, Radiša; Vujanac, Ivan; Sladojević, Željko

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2009)

TY  - JOUR
AU  - Šamanc, Horea
AU  - Kirovski, Danijela
AU  - Prodanović, Radiša
AU  - Vujanac, Ivan
AU  - Sladojević, Željko
PY  - 2009
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/640
AB  - The concentration of total proteins, albumin, total bilirubin, and glucose were examined in the blood of healthy cows and those with left displaced abomasum. Significant digressions from physiological values in cows with left displaced abomasum were established in proteinemia (x = 87.92 g/l) and in bilirubinemia (x = 10.29 μmol/l). Hyperproteinemia indicates chemoconcentration in the diseased animals, which is also indicated in significantly higher concentrations of albumin in the diseased in comparison with the healthy animals (x = 41.94 - 3.5 : 36.89 - 3.95 g/l). The higher values for glucemia in the diseased against the healthy animals (x = 2.628 : 2.203 mmol/l) could indicate disrupted function of B-cells of the endocrine pancreas. This data can come in useful in setting the diagnosis, but it also has no less importance in the determination of the prognosis for the disease. Determining the liver function during the disease should contribute to the better knowledge of its role in the degree of the occurrence of this health disorder, as well as the outcome of the disease itself. This is of particular importance having in mind that displaced abomasum most frequently occurs in the early stage of lactation, when a negative energy balance is already present. This state is conducive to the occurrence of fatty liver, and that is why displaced abomasum can contribute even further to the process of fat accumulation, having in mind that diseased animals consume significantly smaller quantities of feed.
AB  - U krvi zdravih krava i onih obolelih od dislokacije sirišta na levo, ispitivana je koncentracija ukupnih proteina, albumina, ukupnog bilirubina i glukoze. Značajna odstupanja od fizioloških vrednosti kod krava sa dislokacijom sirišta ustanovljena su u proteinemiji (x = 87,92 g/l) i bilirubinemiji (x = 10,29 _mol/l). Hiperproteinemija ukazuje na hemokoncentraciju u obolelih životinja, o čemu svedoči i značajno veća koncentracija albumina kod obolelih u odnosu na zdrave životinje (x = 41,94±3,5:36,89±3,95 g/L). Veće vrednosti glikemije u obolelih u odnosu na zdrave životinje (x = 2,628:2,203 mmol/l) mogu da ukažu na poremećenu funkciju B-ćelija endokrinog pankreasa. Ovaj podatak može biti koristan pri postavljanju dijagnoze, ali ne manji značaj ima i pri proceni prognoze bolesti. Utvrđivanje funkcije jetre tokom bolesti treba da doprinese boljem poznavanju njene uloge u stepenu nastanka poremećaja zdravstvenog stanja kao i samom ishodu bolesti. Ovo je posebno značajno ako se ima u vidu da se dislokacija sirišta najčešće pojavljuje u ranoj fazi laktacije, kada inače postoji negativan bilans energije. Ovo stanje predisponira nastajanje zamašćenja jetre pa zbog toga dislokacija sirišta može još više da doprinese procesu zamašćenja jer bolesne životinje konzumiraju značajno manje količine hrane.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Blood concentration of proteins, bilirubin and glucose in cows with left displaced abomasum
T1  - Koncentracija proteina, bilirubina i glukoze u krvi krava sa dislokacijom sirišta na levo
VL  - 63
IS  - 3-4
SP  - 171
EP  - 176
DO  - 10.2298/VETGL0904171S
ER  - 
@article{
author = "Šamanc, Horea and Kirovski, Danijela and Prodanović, Radiša and Vujanac, Ivan and Sladojević, Željko",
year = "2009",
abstract = "The concentration of total proteins, albumin, total bilirubin, and glucose were examined in the blood of healthy cows and those with left displaced abomasum. Significant digressions from physiological values in cows with left displaced abomasum were established in proteinemia (x = 87.92 g/l) and in bilirubinemia (x = 10.29 μmol/l). Hyperproteinemia indicates chemoconcentration in the diseased animals, which is also indicated in significantly higher concentrations of albumin in the diseased in comparison with the healthy animals (x = 41.94 - 3.5 : 36.89 - 3.95 g/l). The higher values for glucemia in the diseased against the healthy animals (x = 2.628 : 2.203 mmol/l) could indicate disrupted function of B-cells of the endocrine pancreas. This data can come in useful in setting the diagnosis, but it also has no less importance in the determination of the prognosis for the disease. Determining the liver function during the disease should contribute to the better knowledge of its role in the degree of the occurrence of this health disorder, as well as the outcome of the disease itself. This is of particular importance having in mind that displaced abomasum most frequently occurs in the early stage of lactation, when a negative energy balance is already present. This state is conducive to the occurrence of fatty liver, and that is why displaced abomasum can contribute even further to the process of fat accumulation, having in mind that diseased animals consume significantly smaller quantities of feed., U krvi zdravih krava i onih obolelih od dislokacije sirišta na levo, ispitivana je koncentracija ukupnih proteina, albumina, ukupnog bilirubina i glukoze. Značajna odstupanja od fizioloških vrednosti kod krava sa dislokacijom sirišta ustanovljena su u proteinemiji (x = 87,92 g/l) i bilirubinemiji (x = 10,29 _mol/l). Hiperproteinemija ukazuje na hemokoncentraciju u obolelih životinja, o čemu svedoči i značajno veća koncentracija albumina kod obolelih u odnosu na zdrave životinje (x = 41,94±3,5:36,89±3,95 g/L). Veće vrednosti glikemije u obolelih u odnosu na zdrave životinje (x = 2,628:2,203 mmol/l) mogu da ukažu na poremećenu funkciju B-ćelija endokrinog pankreasa. Ovaj podatak može biti koristan pri postavljanju dijagnoze, ali ne manji značaj ima i pri proceni prognoze bolesti. Utvrđivanje funkcije jetre tokom bolesti treba da doprinese boljem poznavanju njene uloge u stepenu nastanka poremećaja zdravstvenog stanja kao i samom ishodu bolesti. Ovo je posebno značajno ako se ima u vidu da se dislokacija sirišta najčešće pojavljuje u ranoj fazi laktacije, kada inače postoji negativan bilans energije. Ovo stanje predisponira nastajanje zamašćenja jetre pa zbog toga dislokacija sirišta može još više da doprinese procesu zamašćenja jer bolesne životinje konzumiraju značajno manje količine hrane.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Blood concentration of proteins, bilirubin and glucose in cows with left displaced abomasum, Koncentracija proteina, bilirubina i glukoze u krvi krava sa dislokacijom sirišta na levo",
volume = "63",
number = "3-4",
pages = "171-176",
doi = "10.2298/VETGL0904171S"
}
Šamanc, H., Kirovski, D., Prodanović, R., Vujanac, I.,& Sladojević, Ž.. (2009). Blood concentration of proteins, bilirubin and glucose in cows with left displaced abomasum. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 63(3-4), 171-176.
https://doi.org/10.2298/VETGL0904171S
Šamanc H, Kirovski D, Prodanović R, Vujanac I, Sladojević Ž. Blood concentration of proteins, bilirubin and glucose in cows with left displaced abomasum. in Veterinarski Glasnik. 2009;63(3-4):171-176.
doi:10.2298/VETGL0904171S .
Šamanc, Horea, Kirovski, Danijela, Prodanović, Radiša, Vujanac, Ivan, Sladojević, Željko, "Blood concentration of proteins, bilirubin and glucose in cows with left displaced abomasum" in Veterinarski Glasnik, 63, no. 3-4 (2009):171-176,
https://doi.org/10.2298/VETGL0904171S . .

Blood calcium and phosphorus concentrations in cows with left displaced abomasum

Šamanc, Horea; Kirovski, Danijela; Savić, Đorđe; Sladojević, Željko; Vujanac, Ivan; Zarcula, Simona

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2009)

TY  - JOUR
AU  - Šamanc, Horea
AU  - Kirovski, Danijela
AU  - Savić, Đorđe
AU  - Sladojević, Željko
AU  - Vujanac, Ivan
AU  - Zarcula, Simona
PY  - 2009
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/588
AB  - Abomasal displacement is one of the most important disorders of the digestive tract in high-yield dairy cows. The etiology and pathogenesis of its occurrence has not been fully clarified to this day. The work examines calcaemia and phosphataemia in cows during the antepartal and postpartal periods and their connection with the incidence of abomasal displacement. The experiment covered 30 cows in advanced stages of gravidity. Blood samples were taken two weeks before expected parturition and two weeks after calving. In all blood samples (taken antepartal and postpartal), concentrations of calcium and an organic phosphorus were determined using a commercial test package (Bio-Merieux). Following parturition, left displacement of the abomasums was established in seven (23.33 %) of the 30 cows covered by the experiment (experimental group). The remaining 23 cows in the experiment were clinically healthy, they were placed in a group and represented control animals. The average value of calcaemia for the control group of cows during the antepartal period was 2.72±0.25 mmol/l, and of phosphataemia 2.04±0.25 mmol/l. In the same cows postpartum, average calcaemia values were 2.46±0.22 mmol/l and phosphataemia 1.85±0.29 mmol/l. The average antepartal value for calcaemia in the experimental group of cows was 2.51±0.25 mmol/l, and for phosphataemia 1.73± 0.22 mmol/l. The average values for this group of cows postpartally was 2.13±0.31 mmol/l for calcaemia and 1.43±0.24 mmol/l for phosphataemia. The differences between the concentration values for calcium and phosphorus obtained postpartally between the experimental and control groups were statistically significant. .
AB  - Promena položaja sirišta je jedno od najznačajnijih oboljenja organa za varenje kod visoko-mlečnih krava. Etiologija i patogeneza njegovog nastanka ni do danas nije u potpunosti objašnjena. U radu je ispitana kalcemija i fosfatemija kod krava u antepartalnom i postpartalnom periodu i njena povezanost sa pojavom promene položaja sirišta. U ogled je bilo uključeno 30 krava u visokom graviditetu. Uzorci krvi uzeti su dve nedelje pre očekivanog partusa, kao i dve nedelje nakon teljenja. U svim uzorcima krvnog seruma (uzetim antepartalno i postpartalno) određivana je koncentracija kalcijuma i anorganskog fosfora, korišćenjem komercijalnih test paketa (Bio-Merieux). Kod 7 krava od 30 uključenih u ogled (23,33%) nakon teljenja je kliničkim pregledom ustanovljena promena položaja sirišta na levo (eksperimentalna grupa). Preostale 23 krave iz ogleda su bile klinički zdrave i predstavljale su kontrolnu grupu. Prosečna vrednost kalcemije kontrolne grupe krava u antepartalnom periodu iznosila je 2,72±0,25 mmol/l, a fosfatemije 2,04±0,25 mmol/l. Kod ovih krava je postpartalno ustanovljena prosečna vrednost kalcemije od 2,46±0,22 mmol/l i fosfatemije od 1,85±0,29 mmol/l. Prosečna antepartalna vrednost kalcemije eksperimentalne grupe krava iznosila je 2,51±0,25 mmol/l, a fosfatemije 1,73±0,22 mmol/l. Postpartalno su prosečne vrednosti kalcemije i fosfatemije ove grupe krava iznosile 2,13±0,31 mmol/l i 1,43± 0,24 mmol/l. Razlike između vrednosti za koncentraciju kalcijuma i fosfora dobijene postpartalno između eksperimentalne i kontrolne grupe su bile statistički značajne.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Blood calcium and phosphorus concentrations in cows with left displaced abomasum
T1  - Koncentracija kalcijuma i fosfora u krvnom serumu krava sa dislokacijom sirišta na levo
VL  - 63
IS  - 5-6
SP  - 331
EP  - 340
DO  - 10.2298/VETGL0906331S
ER  - 
@article{
author = "Šamanc, Horea and Kirovski, Danijela and Savić, Đorđe and Sladojević, Željko and Vujanac, Ivan and Zarcula, Simona",
year = "2009",
abstract = "Abomasal displacement is one of the most important disorders of the digestive tract in high-yield dairy cows. The etiology and pathogenesis of its occurrence has not been fully clarified to this day. The work examines calcaemia and phosphataemia in cows during the antepartal and postpartal periods and their connection with the incidence of abomasal displacement. The experiment covered 30 cows in advanced stages of gravidity. Blood samples were taken two weeks before expected parturition and two weeks after calving. In all blood samples (taken antepartal and postpartal), concentrations of calcium and an organic phosphorus were determined using a commercial test package (Bio-Merieux). Following parturition, left displacement of the abomasums was established in seven (23.33 %) of the 30 cows covered by the experiment (experimental group). The remaining 23 cows in the experiment were clinically healthy, they were placed in a group and represented control animals. The average value of calcaemia for the control group of cows during the antepartal period was 2.72±0.25 mmol/l, and of phosphataemia 2.04±0.25 mmol/l. In the same cows postpartum, average calcaemia values were 2.46±0.22 mmol/l and phosphataemia 1.85±0.29 mmol/l. The average antepartal value for calcaemia in the experimental group of cows was 2.51±0.25 mmol/l, and for phosphataemia 1.73± 0.22 mmol/l. The average values for this group of cows postpartally was 2.13±0.31 mmol/l for calcaemia and 1.43±0.24 mmol/l for phosphataemia. The differences between the concentration values for calcium and phosphorus obtained postpartally between the experimental and control groups were statistically significant. ., Promena položaja sirišta je jedno od najznačajnijih oboljenja organa za varenje kod visoko-mlečnih krava. Etiologija i patogeneza njegovog nastanka ni do danas nije u potpunosti objašnjena. U radu je ispitana kalcemija i fosfatemija kod krava u antepartalnom i postpartalnom periodu i njena povezanost sa pojavom promene položaja sirišta. U ogled je bilo uključeno 30 krava u visokom graviditetu. Uzorci krvi uzeti su dve nedelje pre očekivanog partusa, kao i dve nedelje nakon teljenja. U svim uzorcima krvnog seruma (uzetim antepartalno i postpartalno) određivana je koncentracija kalcijuma i anorganskog fosfora, korišćenjem komercijalnih test paketa (Bio-Merieux). Kod 7 krava od 30 uključenih u ogled (23,33%) nakon teljenja je kliničkim pregledom ustanovljena promena položaja sirišta na levo (eksperimentalna grupa). Preostale 23 krave iz ogleda su bile klinički zdrave i predstavljale su kontrolnu grupu. Prosečna vrednost kalcemije kontrolne grupe krava u antepartalnom periodu iznosila je 2,72±0,25 mmol/l, a fosfatemije 2,04±0,25 mmol/l. Kod ovih krava je postpartalno ustanovljena prosečna vrednost kalcemije od 2,46±0,22 mmol/l i fosfatemije od 1,85±0,29 mmol/l. Prosečna antepartalna vrednost kalcemije eksperimentalne grupe krava iznosila je 2,51±0,25 mmol/l, a fosfatemije 1,73±0,22 mmol/l. Postpartalno su prosečne vrednosti kalcemije i fosfatemije ove grupe krava iznosile 2,13±0,31 mmol/l i 1,43± 0,24 mmol/l. Razlike između vrednosti za koncentraciju kalcijuma i fosfora dobijene postpartalno između eksperimentalne i kontrolne grupe su bile statistički značajne.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Blood calcium and phosphorus concentrations in cows with left displaced abomasum, Koncentracija kalcijuma i fosfora u krvnom serumu krava sa dislokacijom sirišta na levo",
volume = "63",
number = "5-6",
pages = "331-340",
doi = "10.2298/VETGL0906331S"
}
Šamanc, H., Kirovski, D., Savić, Đ., Sladojević, Ž., Vujanac, I.,& Zarcula, S.. (2009). Blood calcium and phosphorus concentrations in cows with left displaced abomasum. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 63(5-6), 331-340.
https://doi.org/10.2298/VETGL0906331S
Šamanc H, Kirovski D, Savić Đ, Sladojević Ž, Vujanac I, Zarcula S. Blood calcium and phosphorus concentrations in cows with left displaced abomasum. in Veterinarski Glasnik. 2009;63(5-6):331-340.
doi:10.2298/VETGL0906331S .
Šamanc, Horea, Kirovski, Danijela, Savić, Đorđe, Sladojević, Željko, Vujanac, Ivan, Zarcula, Simona, "Blood calcium and phosphorus concentrations in cows with left displaced abomasum" in Veterinarski Glasnik, 63, no. 5-6 (2009):331-340,
https://doi.org/10.2298/VETGL0906331S . .