TY  - CONF
AU  - Kirovski, Danijela
AU  - Knežević, Dragan
AU  - Golić, Bojan
AU  - Kasagić, Dragan
AU  - Jovanović, Ljubomir
AU  - Bošnjaković, Dušan
AU  - Trifković, Julijana
AU  - Sladojević, Željko
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2274
AB  - Cow milk is widely consumed by human children and adults due to its nutritional value. Besides
nutrients, milk contains naturally occurring hormones, including insulin like growth factor-1
(IGF-1), that may alter their blood levels in the consumers. At the same time, the impact of IGF1 on human health is still unclear and controversial. The aim of the study was to determine IGF-1
concentrations in cow colostrum and milk and to discuss them from the aspect of human health.
Twenty Holstein cows were enrolled in the study and subjected to colostrum, milk and venous
blood sampling in order to determine the IGF-1 concentration by the radioimmunoassay (RIA).
Colostrum was sampled at 2, 14 and 26 hours (1st, 2nd and 3rd colostrum) after calving, while
milk and venous blood were taken 10 days after calving. The concentration of IGF-1 was the
highest in the 1
st colostrum and decreased significantly with each subsequent sampling, so the
lowest concentrations were detected in milk sampled 10 days after calving. High concentrations
of IGF-1 observed in colostrum, especially in the 1st colostrum, reflect its potential for eventually
use in the treatment of various intestinal diseases. However, further research should determine
the conditions and limitations of its application. On the other hand, additional research is needed
to determine whether IGF-1 in milk has harmful effects on human health and whether it is
necessary to limit the permitted presence of this hormone in cow milk.
PB  - Faculty of Agriculture, Republic of Srpska, Bosnia
C3  - Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“
T1  - Cow milk insulin like growth factor-1: risk or benefit for human health?
SP  - 1196
EP  - 1203
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2274
ER  - 

@conference{
author = "Kirovski, Danijela and Knežević, Dragan and Golić, Bojan and Kasagić, Dragan and Jovanović, Ljubomir and Bošnjaković, Dušan and Trifković, Julijana and Sladojević, Željko",
year = "2021",
abstract = "Cow milk is widely consumed by human children and adults due to its nutritional value. Besides
nutrients, milk contains naturally occurring hormones, including insulin like growth factor-1
(IGF-1), that may alter their blood levels in the consumers. At the same time, the impact of IGF1 on human health is still unclear and controversial. The aim of the study was to determine IGF-1
concentrations in cow colostrum and milk and to discuss them from the aspect of human health.
Twenty Holstein cows were enrolled in the study and subjected to colostrum, milk and venous
blood sampling in order to determine the IGF-1 concentration by the radioimmunoassay (RIA).
Colostrum was sampled at 2, 14 and 26 hours (1st, 2nd and 3rd colostrum) after calving, while
milk and venous blood were taken 10 days after calving. The concentration of IGF-1 was the
highest in the 1
st colostrum and decreased significantly with each subsequent sampling, so the
lowest concentrations were detected in milk sampled 10 days after calving. High concentrations
of IGF-1 observed in colostrum, especially in the 1st colostrum, reflect its potential for eventually
use in the treatment of various intestinal diseases. However, further research should determine
the conditions and limitations of its application. On the other hand, additional research is needed
to determine whether IGF-1 in milk has harmful effects on human health and whether it is
necessary to limit the permitted presence of this hormone in cow milk.",
publisher = "Faculty of Agriculture, Republic of Srpska, Bosnia",
journal = "Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“",
title = "Cow milk insulin like growth factor-1: risk or benefit for human health?",
pages = "1196-1203",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2274"
}

Kirovski, D., Knežević, D., Golić, B., Kasagić, D., Jovanović, L., Bošnjaković, D., Trifković, J.,& Sladojević, Ž.. (2021). Cow milk insulin like growth factor-1: risk or benefit for human health?. in Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“
Faculty of Agriculture, Republic of Srpska, Bosnia., 1196-1203.
https://hdl.handle.net/21.15107/rcub_veterinar_2274

Kirovski D, Knežević D, Golić B, Kasagić D, Jovanović L, Bošnjaković D, Trifković J, Sladojević Ž. Cow milk insulin like growth factor-1: risk or benefit for human health?. in Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“. 2021;:1196-1203.
https://hdl.handle.net/21.15107/rcub_veterinar_2274 .

Kirovski, Danijela, Knežević, Dragan, Golić, Bojan, Kasagić, Dragan, Jovanović, Ljubomir, Bošnjaković, Dušan, Trifković, Julijana, Sladojević, Željko, "Cow milk insulin like growth factor-1: risk or benefit for human health?" in Proceedings of the XII International Scientific Agricultural Symposium „Agrosym 2021“ (2021):1196-1203,
https://hdl.handle.net/21.15107/rcub_veterinar_2274 .