An outbreak of fumonisin toxicosis in horses in Serbia
Само за регистроване кориснике
2015
Аутори
Jovanović, M.Trailović, Dragiša
Kukolj, Vladimir
Nešić, Slađan
Marinković, Darko
Nedeljković-Trailović, Jelena
Strajn, B. Jakovac
Milićević, Dragan
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
This paper reports on an outbreak of fumonisin toxicosis in a stable with 100 horses. Twenty-one horses were affected and fifteen died within a month. The animals were not febrile and exhibited poor appetite, somnolence, head pressing, blindness, ataxia, lethargy, and seizures, ending with death. The post mortem examination of the head of one 18-month-old colt revealed large, bilateral, slightly asymmetrical large areas of necrosis of the cerebral white matter. The lesions involved the frontal, parietal and occipital lobes only. Histological findings revealed leukomalacia with necrosis, infiltration of macrophages, neutrophils and eosinophils, haemorrhage and oedema of the surrounding grey matter. In response to the pathological findings, which indicated equine leukoencephalomalacia (ELEM), feed samples from the premises were tested for fumonisin B-1 and B-2 (FB1 and FB2). The milled maize samples contained 6.0 mg/kg FB1 and 2.4 mg/kg FB2, while the maize bran contained 6.05 mg/kg FB1 ...and 1.68 mg/kg FB2. These findings confirmed the diagnosis of fumonisin toxicosis. Hence, this report indicates that Serbia is one of the few regions in Europe with proven cases of ELEM.
Кључне речи:
equine / leukoencephalomalacia / mycotoxins / fumonisinИзвор:
World Mycotoxin Journal, 2015, 8, 4, 387-391Издавач:
- Wageningen Academic Publishers, Wageningen
DOI: 10.3920/WMJ2014.1812
ISSN: 1875-0710
WoS: 000360184800001
Scopus: 2-s2.0-84945566774
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Jovanović, M. AU - Trailović, Dragiša AU - Kukolj, Vladimir AU - Nešić, Slađan AU - Marinković, Darko AU - Nedeljković-Trailović, Jelena AU - Strajn, B. Jakovac AU - Milićević, Dragan PY - 2015 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1287 AB - This paper reports on an outbreak of fumonisin toxicosis in a stable with 100 horses. Twenty-one horses were affected and fifteen died within a month. The animals were not febrile and exhibited poor appetite, somnolence, head pressing, blindness, ataxia, lethargy, and seizures, ending with death. The post mortem examination of the head of one 18-month-old colt revealed large, bilateral, slightly asymmetrical large areas of necrosis of the cerebral white matter. The lesions involved the frontal, parietal and occipital lobes only. Histological findings revealed leukomalacia with necrosis, infiltration of macrophages, neutrophils and eosinophils, haemorrhage and oedema of the surrounding grey matter. In response to the pathological findings, which indicated equine leukoencephalomalacia (ELEM), feed samples from the premises were tested for fumonisin B-1 and B-2 (FB1 and FB2). The milled maize samples contained 6.0 mg/kg FB1 and 2.4 mg/kg FB2, while the maize bran contained 6.05 mg/kg FB1 and 1.68 mg/kg FB2. These findings confirmed the diagnosis of fumonisin toxicosis. Hence, this report indicates that Serbia is one of the few regions in Europe with proven cases of ELEM. PB - Wageningen Academic Publishers, Wageningen T2 - World Mycotoxin Journal T1 - An outbreak of fumonisin toxicosis in horses in Serbia VL - 8 IS - 4 SP - 387 EP - 391 DO - 10.3920/WMJ2014.1812 ER -
@article{ author = "Jovanović, M. and Trailović, Dragiša and Kukolj, Vladimir and Nešić, Slađan and Marinković, Darko and Nedeljković-Trailović, Jelena and Strajn, B. Jakovac and Milićević, Dragan", year = "2015", abstract = "This paper reports on an outbreak of fumonisin toxicosis in a stable with 100 horses. Twenty-one horses were affected and fifteen died within a month. The animals were not febrile and exhibited poor appetite, somnolence, head pressing, blindness, ataxia, lethargy, and seizures, ending with death. The post mortem examination of the head of one 18-month-old colt revealed large, bilateral, slightly asymmetrical large areas of necrosis of the cerebral white matter. The lesions involved the frontal, parietal and occipital lobes only. Histological findings revealed leukomalacia with necrosis, infiltration of macrophages, neutrophils and eosinophils, haemorrhage and oedema of the surrounding grey matter. In response to the pathological findings, which indicated equine leukoencephalomalacia (ELEM), feed samples from the premises were tested for fumonisin B-1 and B-2 (FB1 and FB2). The milled maize samples contained 6.0 mg/kg FB1 and 2.4 mg/kg FB2, while the maize bran contained 6.05 mg/kg FB1 and 1.68 mg/kg FB2. These findings confirmed the diagnosis of fumonisin toxicosis. Hence, this report indicates that Serbia is one of the few regions in Europe with proven cases of ELEM.", publisher = "Wageningen Academic Publishers, Wageningen", journal = "World Mycotoxin Journal", title = "An outbreak of fumonisin toxicosis in horses in Serbia", volume = "8", number = "4", pages = "387-391", doi = "10.3920/WMJ2014.1812" }
Jovanović, M., Trailović, D., Kukolj, V., Nešić, S., Marinković, D., Nedeljković-Trailović, J., Strajn, B. J.,& Milićević, D.. (2015). An outbreak of fumonisin toxicosis in horses in Serbia. in World Mycotoxin Journal Wageningen Academic Publishers, Wageningen., 8(4), 387-391. https://doi.org/10.3920/WMJ2014.1812
Jovanović M, Trailović D, Kukolj V, Nešić S, Marinković D, Nedeljković-Trailović J, Strajn BJ, Milićević D. An outbreak of fumonisin toxicosis in horses in Serbia. in World Mycotoxin Journal. 2015;8(4):387-391. doi:10.3920/WMJ2014.1812 .
Jovanović, M., Trailović, Dragiša, Kukolj, Vladimir, Nešić, Slađan, Marinković, Darko, Nedeljković-Trailović, Jelena, Strajn, B. Jakovac, Milićević, Dragan, "An outbreak of fumonisin toxicosis in horses in Serbia" in World Mycotoxin Journal, 8, no. 4 (2015):387-391, https://doi.org/10.3920/WMJ2014.1812 . .