Neutrophil phagocytosis and respiratory burst activity of dairy cows during the transition period and early lactation
2018
Autori
Zekic-Stosić, MarinaKanacki, Zdenko
Stojanović, Dragica
Bugarski, Dejan
Lazarević, Miodrag
Milovanović, Aleksandar
Masić, Aleksandar
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Introduction: Hormonal and metabolic changes, as well as energy imbalance, can affect health, production and reproductive performance of dairy cows. In the present study, we evaluated phagocytosis and respiratory burst neutrophil activity during the transition period and early lactation and compared it with biochemical and hematological parameters in dairy cows. Methodology: Simmental cows (n = 21) were enrolled in the study. Whole blood samples were collected weekly from 3 weeks pre- calving until 6 weeks post calving. Basic metabolic and blood parameters were assessed by routine laboratory analyses, while neutrophil functions were analyzed by commercial test kits. Results: Optimal neutrophil response was observed pre and post calving. The highest value was recorded in the 6th week after calving (89.54 +/- 7.61%) and being significantly higher (p < 0.01) as compared to values recorded at two and one week before and one week after calving. The percentage of activated neutrophils was hi...gh during the entire study period: from 70.80 +/- 5.22% at the beginning of the study to 89.54 +/- 7.61% at the end of the study. During the study period, production of Reactive Oxidative Species by neutrophils was positively correlated with beta-hydroxybutyrat and non-esteri tied fatty acids values (0.454** and 0.423**, respectively) and calcium levels (0.164* and 0.212**, respectively). Conclusions: The most prominent changes in all parameters had no influence on phagocytic and respiratory burst activity of neutrophils. Neutrophil function is preserved at the optimal level during the transition period and early lactation in Simmental cows.
Ključne reči:
dairy cows / neutrophil / phagocytosis / respiratory burstIzvor:
Journal of Infection in Developing Countries, 2018, 12, 10, 894-Izdavač:
- J Infection Developing Countries, Tramaniglio
Finansiranje / projekti:
- Istraživanje farmakoloških karakteristika antimikrobnih agenasa, uvođenje novih tehnoloških rešenja i alternativnih metoda profilakse s ciljem da se poboljša kontrola infektivnih oboljenja domaćih životinja (RS-MESTD-Technological Development (TD or TR)-31071)
DOI: 10.3855/jidc.10767
ISSN: 1972-2680
PubMed: 32004159
WoS: 000449742200011
Scopus: 2-s2.0-85060945220
Kolekcije
Institucija/grupa
Fakultet veterinarske medicineTY - JOUR AU - Zekic-Stosić, Marina AU - Kanacki, Zdenko AU - Stojanović, Dragica AU - Bugarski, Dejan AU - Lazarević, Miodrag AU - Milovanović, Aleksandar AU - Masić, Aleksandar PY - 2018 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1593 AB - Introduction: Hormonal and metabolic changes, as well as energy imbalance, can affect health, production and reproductive performance of dairy cows. In the present study, we evaluated phagocytosis and respiratory burst neutrophil activity during the transition period and early lactation and compared it with biochemical and hematological parameters in dairy cows. Methodology: Simmental cows (n = 21) were enrolled in the study. Whole blood samples were collected weekly from 3 weeks pre- calving until 6 weeks post calving. Basic metabolic and blood parameters were assessed by routine laboratory analyses, while neutrophil functions were analyzed by commercial test kits. Results: Optimal neutrophil response was observed pre and post calving. The highest value was recorded in the 6th week after calving (89.54 +/- 7.61%) and being significantly higher (p < 0.01) as compared to values recorded at two and one week before and one week after calving. The percentage of activated neutrophils was high during the entire study period: from 70.80 +/- 5.22% at the beginning of the study to 89.54 +/- 7.61% at the end of the study. During the study period, production of Reactive Oxidative Species by neutrophils was positively correlated with beta-hydroxybutyrat and non-esteri tied fatty acids values (0.454** and 0.423**, respectively) and calcium levels (0.164* and 0.212**, respectively). Conclusions: The most prominent changes in all parameters had no influence on phagocytic and respiratory burst activity of neutrophils. Neutrophil function is preserved at the optimal level during the transition period and early lactation in Simmental cows. PB - J Infection Developing Countries, Tramaniglio T2 - Journal of Infection in Developing Countries T1 - Neutrophil phagocytosis and respiratory burst activity of dairy cows during the transition period and early lactation VL - 12 IS - 10 SP - 894 DO - 10.3855/jidc.10767 ER -
@article{ author = "Zekic-Stosić, Marina and Kanacki, Zdenko and Stojanović, Dragica and Bugarski, Dejan and Lazarević, Miodrag and Milovanović, Aleksandar and Masić, Aleksandar", year = "2018", abstract = "Introduction: Hormonal and metabolic changes, as well as energy imbalance, can affect health, production and reproductive performance of dairy cows. In the present study, we evaluated phagocytosis and respiratory burst neutrophil activity during the transition period and early lactation and compared it with biochemical and hematological parameters in dairy cows. Methodology: Simmental cows (n = 21) were enrolled in the study. Whole blood samples were collected weekly from 3 weeks pre- calving until 6 weeks post calving. Basic metabolic and blood parameters were assessed by routine laboratory analyses, while neutrophil functions were analyzed by commercial test kits. Results: Optimal neutrophil response was observed pre and post calving. The highest value was recorded in the 6th week after calving (89.54 +/- 7.61%) and being significantly higher (p < 0.01) as compared to values recorded at two and one week before and one week after calving. The percentage of activated neutrophils was high during the entire study period: from 70.80 +/- 5.22% at the beginning of the study to 89.54 +/- 7.61% at the end of the study. During the study period, production of Reactive Oxidative Species by neutrophils was positively correlated with beta-hydroxybutyrat and non-esteri tied fatty acids values (0.454** and 0.423**, respectively) and calcium levels (0.164* and 0.212**, respectively). Conclusions: The most prominent changes in all parameters had no influence on phagocytic and respiratory burst activity of neutrophils. Neutrophil function is preserved at the optimal level during the transition period and early lactation in Simmental cows.", publisher = "J Infection Developing Countries, Tramaniglio", journal = "Journal of Infection in Developing Countries", title = "Neutrophil phagocytosis and respiratory burst activity of dairy cows during the transition period and early lactation", volume = "12", number = "10", pages = "894", doi = "10.3855/jidc.10767" }
Zekic-Stosić, M., Kanacki, Z., Stojanović, D., Bugarski, D., Lazarević, M., Milovanović, A.,& Masić, A.. (2018). Neutrophil phagocytosis and respiratory burst activity of dairy cows during the transition period and early lactation. in Journal of Infection in Developing Countries J Infection Developing Countries, Tramaniglio., 12(10), 894. https://doi.org/10.3855/jidc.10767
Zekic-Stosić M, Kanacki Z, Stojanović D, Bugarski D, Lazarević M, Milovanović A, Masić A. Neutrophil phagocytosis and respiratory burst activity of dairy cows during the transition period and early lactation. in Journal of Infection in Developing Countries. 2018;12(10):894. doi:10.3855/jidc.10767 .
Zekic-Stosić, Marina, Kanacki, Zdenko, Stojanović, Dragica, Bugarski, Dejan, Lazarević, Miodrag, Milovanović, Aleksandar, Masić, Aleksandar, "Neutrophil phagocytosis and respiratory burst activity of dairy cows during the transition period and early lactation" in Journal of Infection in Developing Countries, 12, no. 10 (2018):894, https://doi.org/10.3855/jidc.10767 . .