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Altered state of primordial follicles in neonatal and early infantile rats due to maternal hypothyroidism: Light and electron microscopy approach
(Pergamon-Elsevier Science Ltd, Oxford, 2016)
Thyroid hormones (TH) are one of the key factors for normal prenatal development in mammals. Previously, we showed that subclinical maternal hypothyroidism leads to premature atresia of ovarian follicles in female rat ...
Response of adult honey bees treated in larval stage with prochloraz to infection with Nosema ceranae
(Peerj Inc, London, 2019)
Among numerous factors that contribute to honey bee colony losses and problems in beekeeping, pesticides and Nosema ceranae have been often reported. In contrast to insecticides, whose effects on bees have been widely ...
Inhibition of Salmonella by thyme essential oil and its effect on microbiological and sensory properties of minced pork meat packaged under vacuum and modified atmosphere
(Elsevier, Amsterdam, 2017)
The antibacterial activity of thyme essential oil (TEO) was evaluated against four serovars of Salmonella (S. Enteritidis, S. Typhimurium, S. Montevideo and S. Infantis), experimentally inoculated (10(6) CFU/g) in minced ...
Ruthenium(II)-N-alkyl phenothiazine complexes as potential anticancer agents
(Springer, New York, 2018)
In recent years, the search for effective anticancer compounds based on transition metal complexes has been the focus of medical investigations. The synergy between the ruthenium(II) and N-alkylphenothiazine counter-ions ...
Disulfiram moderately restores impaired hepatic redox status of rats subchronically exposed to cadmium
(Taylor & Francis Ltd, Abingdon, 2017)
Examination of cadmium (Cd) toxicity and disulfiram (DSF) effect on liver was focused on oxidative stress (OS), bioelements status, morphological and functional changes. Male Wistar rats were intraperitoneally treated with ...
Voltammetric determination of an antipsychotic agent trifluoperazine at a boron-doped diamond electrode in human urine
(Royal Soc Chemistry, Cambridge, 2015)
A simple and efficient procedure is described for electrochemical determination of trifluoperazine (TFP), a prominent compound in a large group of phenothiazine derivatives with potent physiological activity. This method ...
Nitroso-Oxidative Stress, Acute Phase Response, and Cytogenetic Damage in Wistar Rats Treated with Adrenaline
(Hindawi Ltd, London, 2018)
This study is aimed at analysing biochemical and genetic endpoints of toxic effects after administration of adrenaline. For this purpose, the study was carried out on Wistar rats and three doses of adrenaline were used: ...
Synthesis, structural and spectroscopic characterization, in vitro cytotoxicity and in vivo activity as free radical scavengers of chlorido(p-cymene) complexes of ruthenium(II) containing N-alkylphenothiazines
(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2011)
Three new ruthenium(II) complexes 1-3 containing N-alkylphenothiazine molecules were synthesized by reaction of [RuCl2(eta(6)-P-cymene)](2) with chlorpromazine hydrochloride (1), trifluoperazine dihydrochloride (2) or ...