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Enhanced sister-chromatid exchange rate in human lymphocytes exposed to 17 beta estradiol in vitro
(Elsevier Science Inc, New York, 2002)
Background. Epidemiologic data and animal experiments strongly implicate that steroid hormones are involved in the process of malignant transformation due to their capability to stimulate mitotic division and/or elevate ...
Monitoring of mitotic index and frequency of micronuclei in evaluation of genotoxic potential of fumagillin (dicyclohexylamine) in vivo / Praćenje mitotskog indeksa i učestalosti mikronukleusa u funkciji procene genotoksičnog potencijala fumagilina (dicikloheksilamina) in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2006)
Fumagillin (dicyclohexylamine) is a natural antibiotic, secreted by Aspergillus fumigatus. It is used in veterinary medicine against microsporidiosis in bees and fish, as well as in human medicine for the treatment of ...
Frequency of chromosomal aberrations in the evaluation of genotoxic potential of dicyclohexylamine (fumagillin) in vivo / Učestalost hromozomskih aberacija u funkciji evaluacije genotoksičnog potencijala fumagilina in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2006)
Dicyclohexylamine (fumagillin), as an antibiotic produced by fermentation of Aspergillus fumigatus, is used in human medicine for the treatment of intestinal microsporidiosis in patients with HIV infection, intestinal ...
Mutagenous effects of hormones / Mutageni efekti hormona
(Univerzitet u Nišu - Medicinski fakultet, Niš, 2001)
There is a widely accepted view that the endogenous substances, including hormones, do not have any mutagenous effect when present in the usual physiological concentrations. However, beside relative stability and permanence ...
Effects of cymiazole hydrochloride on sister-chromatid exchanges, mitotic and proliferation indices in cultured human lymphocytes / Delovanje cimiazol hidrohlorida na razmenu sestrinskih hromatida, mitotski i proliferativni indeks u kulturama humanih limfocita
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2003)
Cymiazole hydrochloride is the active component of the acaricides and Apichem which are used as varroacide in beekeeping. Since residues of cymiazole hydrochloride were detected in all bee products being used for human ...
Evaluation of genotoxic potential of amitraz by cytogenetic test in vivo / Evaluacija genotoksičnog potencijala amitraza citogenetičkim testom in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2006)
The genotoxic effect of amitraz (3.6 mg/kg b.m, 1.8 mg/kg b.m, 0.9 mg/kg b.m) on bone marrow cells of HAN strain mice was examined in vivo by following the frequency of numeric and structural chromosomal aberrations, while ...
Examination of Carbadox genotoxicity in vitro and in vivo / Ispitivanje genotoksičnog efekta Carbadoxa in vitro i in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2000)
Due to its bactericidal activity Carbadox is used for treatment of swine dysentery and salmonellosis. Also, it can be used as a factor for growth stimulation. Carbadox is the only drug for certain health problems in swine ...
Evaluation of the genotoxic effects of thyroxine using in vivo cytogenetic test on Swiss albino mice / Evaluacija genotoksičnih efekata tiroksina primenom in vivo citogenetičkog testa na Swiss albino miševima
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2007)
Thyroid hormones enhance aerobic metabolism favoring oxidative stress which may lead to covalent damage of various molecules including DNA. Previous investigations revealed that thyroid hormones induce DNA damage on human ...
Examination of 8-CI-cAMP genotoxicity by two in vivo test in BALB/c strain mice / Ispitivanje genotoksičnosti 8-CI-cAMP u dva in vivo testa na miševima soja BALB/c
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2000)
The antitumor agent 8-CI-cAMP (8-chloro-cyclic adenosine monophosphate) is the most potent site-selective analogue of cAMP. It acts primarily by selective down-regulation of regulatory sub-units of cAMP-dependent protein ...
Cytogenetic analysis of the effects of epinephrine on cultured human lymphocytes / Citogenetička analiza dejstva adrenalina na humane limfocite u kulturi
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2003)
Epinephrine can modulate mitotic activity of normal and malignant cells and exhibit genotoxic potential in some test-systems. It is assumed that metabolic conversion of phenolic groups in the catechol ring of epinephrine ...