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Carvacrol acts as a potent selective antagonist of different types of nicotinic acetylcholine receptors and enhances the effect of monepantel in the parasitic nematode Ascaris suum
(Elsevier, Amsterdam, 2020)
The neuromuscular system of parasitic nematodes has proven to be an efficient pharmacological target for antihelmintics. Some of the most frequently used antiparasitic drugs are agonists or antagonists of nicotinic ...
Systemic inflammatory response syndrome in dogs naturally infected with Babesia canis: Association with the parasite load and host factors
(Elsevier, 2021)
The common signs of canine babesiosis caused by an infection with Babesia canis are fever, anorexia, lethargy, pulse alterations, anemia, and occasionally mild icterus. Dogs with these clinical signs can be divided into ...
Low serum levels of promatrix metalloproteinase-2 and -9 occur during acute Babesia canis infection in dogs
(Elsevier, 2021)
Inflammation is a hallmark of the acute Babesia canis infection. Promatrix metalloproteinase (proMMP)-2 and -9 are involved in inflammation, but their levels have not been analyzed in canine babesiosis. We hypothesized ...
Evidence of acute phase reaction in asymptomatic dogs naturally infected with Babesia canis
(Elsevier Science Bv, Amsterdam, 2020)
Asymptomatic outdoor dogs can be carriers of Babesia canis, but data describing the development of an acute phase response (APR) are not available. We hypothesised that these dogs have a moderate APR that could be detected ...