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Is the time dimension of the cell cycle re-entry in AD regulated by centromere cohesion dynamics?
(Bioscience Hypotheses, 2008)
Chromosomal involvement is a legitimate, yet not well understood, feature of Alzheimer disease (AD). Firstly, AD affects more women than men. Secondly, the amyloid-β protein precursor genetic mutations, responsible for a ...
Analysis of premature centromere division (PCD) of the X chromosome in Alzheimer patients through the cell cycle
(Pergamon-Elsevier Science Ltd, Oxford, 2004)
Cytogenetic analysis of the X chromosome in phytohaemagglutinin stimulated peripheral blood lymphocytes was evaluated in 12 sporadic Alzheimer disease (AD) patients and in 11 healthy subjects. For chromosome analysis two ...
Analysis of premature centromere division (PCD) of the chromosome 18 in peripheral blood lymphocytes of Alzheimer disease patients
(Elsevier, 2006)
Premature centromere division (PCD) of the chromosome 18 was analyzed by using fluorescent in situ hybridization (FISH) on interphase peripheral blood lymphocytes isolated from six sporadic Alzheimer disease (AD) patients ...