TY  - JOUR
AU  - Marić, Jelena S.
AU  - Nedić, Drago
AU  - Vejnović, Branislav
AU  - Velić, Lejla
AU  - Obrenović, Sonja
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3263
AB  - The aim of this study was to examine the seroprevalence of Leptospira spp. in dogs and
red foxes in the entity of the Republic of Srpska, Bosnia and Herzegovina, after heavy
rainfall and floods in 2014 and for the two years thereafter. The seroepidemiological
study involved testing serum samples from dogs (n = 98) and foxes (n = 112) using
MAT (microscopic agglutination test).
Antibodies to at least one Leptospira spp. serovar were found in 52.04% of the tested
dogs. The dog seroprevalence in 2014 (81.25%) was significantly higher than in 2015
(51.42% p <0.0001) and 2016 (22.5% p<0.05). The highest seroprevalences were for
serovars Australis (76.47%), Bratislava (70.58%), Sejroe (66.67%) and Autumnalis
(45.09%).
Antibodies to at least one Leptospira spp. serovar were detected in 34.82% of the
examined red foxes. In 2015, the fox seroprevalence was significantly higher (52.94%)
than in 2016 (6.82%) (p <0.0001). The highest seroprevalences were for serovars Sejroe
(64.10%), Bratislava (48.72%), Australis (43.59%) and Bataviae (25.64%).
The high seroprevalence of Leptospira spp. in dogs and foxes determined during this
study indicates the importance of these carnivores in maintaining leptospirosis in the
study area, and the potential risk of infection for humans and other animal species that
come into contact with these canids. The results obtained indicate that heavy rainfall
and intense floods can result in increased Leptospira spp. infection in these canids.
PB  - Beograd : Fakultet veterinarske medicine
T2  - Acta Veterinaria
T1  - Seroprevalence of serovars of pathogenic Leptospira in dogs and red foxes (Vulpes vulpes) from Bosnia and Herzegovina
VL  - 73
IS  - 3
SP  - 389
EP  - 404
DO  - 10.2478/acve-2023-0029
ER  - 

@article{
author = "Marić, Jelena S. and Nedić, Drago and Vejnović, Branislav and Velić, Lejla and Obrenović, Sonja",
year = "2023",
abstract = "The aim of this study was to examine the seroprevalence of Leptospira spp. in dogs and
red foxes in the entity of the Republic of Srpska, Bosnia and Herzegovina, after heavy
rainfall and floods in 2014 and for the two years thereafter. The seroepidemiological
study involved testing serum samples from dogs (n = 98) and foxes (n = 112) using
MAT (microscopic agglutination test).
Antibodies to at least one Leptospira spp. serovar were found in 52.04% of the tested
dogs. The dog seroprevalence in 2014 (81.25%) was significantly higher than in 2015
(51.42% p <0.0001) and 2016 (22.5% p<0.05). The highest seroprevalences were for
serovars Australis (76.47%), Bratislava (70.58%), Sejroe (66.67%) and Autumnalis
(45.09%).
Antibodies to at least one Leptospira spp. serovar were detected in 34.82% of the
examined red foxes. In 2015, the fox seroprevalence was significantly higher (52.94%)
than in 2016 (6.82%) (p <0.0001). The highest seroprevalences were for serovars Sejroe
(64.10%), Bratislava (48.72%), Australis (43.59%) and Bataviae (25.64%).
The high seroprevalence of Leptospira spp. in dogs and foxes determined during this
study indicates the importance of these carnivores in maintaining leptospirosis in the
study area, and the potential risk of infection for humans and other animal species that
come into contact with these canids. The results obtained indicate that heavy rainfall
and intense floods can result in increased Leptospira spp. infection in these canids.",
publisher = "Beograd : Fakultet veterinarske medicine",
journal = "Acta Veterinaria",
title = "Seroprevalence of serovars of pathogenic Leptospira in dogs and red foxes (Vulpes vulpes) from Bosnia and Herzegovina",
volume = "73",
number = "3",
pages = "389-404",
doi = "10.2478/acve-2023-0029"
}

Marić, J. S., Nedić, D., Vejnović, B., Velić, L.,& Obrenović, S.. (2023). Seroprevalence of serovars of pathogenic Leptospira in dogs and red foxes (Vulpes vulpes) from Bosnia and Herzegovina. in Acta Veterinaria
Beograd : Fakultet veterinarske medicine., 73(3), 389-404.
https://doi.org/10.2478/acve-2023-0029

Marić JS, Nedić D, Vejnović B, Velić L, Obrenović S. Seroprevalence of serovars of pathogenic Leptospira in dogs and red foxes (Vulpes vulpes) from Bosnia and Herzegovina. in Acta Veterinaria. 2023;73(3):389-404.
doi:10.2478/acve-2023-0029 .

Marić, Jelena S., Nedić, Drago, Vejnović, Branislav, Velić, Lejla, Obrenović, Sonja, "Seroprevalence of serovars of pathogenic Leptospira in dogs and red foxes (Vulpes vulpes) from Bosnia and Herzegovina" in Acta Veterinaria, 73, no. 3 (2023):389-404,
https://doi.org/10.2478/acve-2023-0029 . .

TY  - CONF
AU  - Obrenović, Sonja
AU  - Laušević, Dejan
AU  - Konstantinov, Jelena
AU  - Grgić, Živoslav
AU  - Vakanjac, Slobodanka
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3288
AB  - Q groznica i dalje predstavlja veliki zdravstvani problem, kako u veterinarskoj,
tako i u humanoj medicini. Infekcija C. burnetii utvrđena je kod različitih vrsta
životinja, a domaći preživari predstavljaju najvažnije rezervoare i izvore zaraze za
infekciju ljudi. Kod preživara infekcija C. burnetii je najčešće supklinička ili se manifestuje
reproduktivnim poremećajima, kao što su pobačaj, prevremeni porođaj,
rađanje mrtvih ili slabovitalnih plodova, neplodnost i supklinički mastitis. Masovno
izlučivanje C. burnetii u životnu sredinu dešava se tokom pobačaja ili porođaja,
kao i vaginalnim iscedkom, urinom, fecesom i mlekom koje može trajati mesecima.
Do infekcije ljudi i životinja najčešće dolazi putem infektivnog aerosola koji se
stvara nakon izlučivanja velike količine uzročnika u spoljašnju sredinu. Dostupni
dijagnostički testovi imaju ograničenu osetljivost, što u kombinaciji sa odsustvom
mogućnosti lečenja kod životinja, i ograničenim mogućnostima prevencije dovode
do teškoća u kontroli infekcija izazvanih sa C. burnetii. Jedan od glavnih ciljeva
nadzora infekcije C. burnetii je otkrivanje životinja “izlučivača” u ranoj fazi, tako da
se kontaminacija životne sredine i izlaganje ljudi mogu sprečiti ili svesti na minimum.
Imajući u vidu da su kontakti sa inficiranim preživarima jedan od najvažnijih
faktora za infekciju ljudi otkrivanje i kontrola zaraženih stada ima ključnu ulogu u
kontroli Q groznice iz perspektive javnog zdravlja.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 14. Naučni simpozijum Reprodukcija životinja, Divčibare, 12 - 15. oktobar 2023
T1  - Q groznica preživara – rizik za javno zdravlje
SP  - 179
EP  - 186
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3288
ER  - 

@conference{
author = "Obrenović, Sonja and Laušević, Dejan and Konstantinov, Jelena and Grgić, Živoslav and Vakanjac, Slobodanka",
year = "2023",
abstract = "Q groznica i dalje predstavlja veliki zdravstvani problem, kako u veterinarskoj,
tako i u humanoj medicini. Infekcija C. burnetii utvrđena je kod različitih vrsta
životinja, a domaći preživari predstavljaju najvažnije rezervoare i izvore zaraze za
infekciju ljudi. Kod preživara infekcija C. burnetii je najčešće supklinička ili se manifestuje
reproduktivnim poremećajima, kao što su pobačaj, prevremeni porođaj,
rađanje mrtvih ili slabovitalnih plodova, neplodnost i supklinički mastitis. Masovno
izlučivanje C. burnetii u životnu sredinu dešava se tokom pobačaja ili porođaja,
kao i vaginalnim iscedkom, urinom, fecesom i mlekom koje može trajati mesecima.
Do infekcije ljudi i životinja najčešće dolazi putem infektivnog aerosola koji se
stvara nakon izlučivanja velike količine uzročnika u spoljašnju sredinu. Dostupni
dijagnostički testovi imaju ograničenu osetljivost, što u kombinaciji sa odsustvom
mogućnosti lečenja kod životinja, i ograničenim mogućnostima prevencije dovode
do teškoća u kontroli infekcija izazvanih sa C. burnetii. Jedan od glavnih ciljeva
nadzora infekcije C. burnetii je otkrivanje životinja “izlučivača” u ranoj fazi, tako da
se kontaminacija životne sredine i izlaganje ljudi mogu sprečiti ili svesti na minimum.
Imajući u vidu da su kontakti sa inficiranim preživarima jedan od najvažnijih
faktora za infekciju ljudi otkrivanje i kontrola zaraženih stada ima ključnu ulogu u
kontroli Q groznice iz perspektive javnog zdravlja.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "14. Naučni simpozijum Reprodukcija životinja, Divčibare, 12 - 15. oktobar 2023",
title = "Q groznica preživara – rizik za javno zdravlje",
pages = "179-186",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3288"
}

Obrenović, S., Laušević, D., Konstantinov, J., Grgić, Ž.,& Vakanjac, S.. (2023). Q groznica preživara – rizik za javno zdravlje. in 14. Naučni simpozijum Reprodukcija životinja, Divčibare, 12 - 15. oktobar 2023
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 179-186.
https://hdl.handle.net/21.15107/rcub_veterinar_3288

Obrenović S, Laušević D, Konstantinov J, Grgić Ž, Vakanjac S. Q groznica preživara – rizik za javno zdravlje. in 14. Naučni simpozijum Reprodukcija životinja, Divčibare, 12 - 15. oktobar 2023. 2023;:179-186.
https://hdl.handle.net/21.15107/rcub_veterinar_3288 .

Obrenović, Sonja, Laušević, Dejan, Konstantinov, Jelena, Grgić, Živoslav, Vakanjac, Slobodanka, "Q groznica preživara – rizik za javno zdravlje" in 14. Naučni simpozijum Reprodukcija životinja, Divčibare, 12 - 15. oktobar 2023 (2023):179-186,
https://hdl.handle.net/21.15107/rcub_veterinar_3288 .

TY  - CONF
AU  - Bacić, Dragan
AU  - Obrenović, Sonja
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3114
AB  - Maligna kataralna groznica (MKG) je akutna, generalizovana i često fatalna
bolest papkara (Artiodactyla) – goveda, bizona, jelena i dr., koja se karakteriše
opštim infektivnim sindromom, kataralno krupoznom upalom sluznica glave i
digestivnog trakta, keratokonjunktivitisom i neurološkim simptomima. Uzročnik bolesti je DNK virus, koji pripada familiji Herpesviridae, subfamiliji
Gammaherpesvirinae, rodu Macavirus, koji obuhvata deset vrsta virusa. Najviše proučavani tipovi su alcelafinski herpesvirus 1 (AlHV-1) i ovčiji herpesvirus 2 (OvHV-2). Svaki tip virusa je prilagođen svom domaćinu, kod koga
ne dovodi do oboljenja, ali može izazvati simptome bolesti ili uginuća kod
drugih osetljivih vrsta. Druge životinjske vrste se zaraze ukoliko borave u istom
prostoru ili su na paši sa primarnim domaćinom. Najosetljivije životinje su
goveda, jeleni, antilope, žirafe, bizoni, a nekoliko slučajeva MKG je prijavljeno
kod jelena i losova u zoološkim vrtovima. Bolest je kod domaćih svinja dijagnostikovana u nekoliko zemalja. Infekcija se retko prenosi horizontalnim putem sa goveda na govedo, pa je za širenje infekcije i pojavu bolesti najbitnija
kohabitacija malih i velikih preživara. Goveda najčeće obole kada se drže
zajedno sa ovcama koje su gravidne ili su tek ojagnjene. Prijemčive su sve
starosne kategorije goveda, ali se MKG najčešće javlja kod jedinki starijih od
dve godine. MKG se pojavljuje u mnogim zemljama Afrike, Evrope, Azije i Amerike. Trenutno ne postoji adekvatna terapija ili komercijalna vakcina. Maligna
kataralna groznica nije zoonoza.
PB  - Beograd : Fakultet veterinarske medicine
C3  - Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023
T1  - Maligna kataralna groznica – uloga ovaca i koza kao izvora infekcije za goveda
SP  - 182
EP  - 190
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3114
ER  - 

@conference{
author = "Bacić, Dragan and Obrenović, Sonja",
year = "2023",
abstract = "Maligna kataralna groznica (MKG) je akutna, generalizovana i često fatalna
bolest papkara (Artiodactyla) – goveda, bizona, jelena i dr., koja se karakteriše
opštim infektivnim sindromom, kataralno krupoznom upalom sluznica glave i
digestivnog trakta, keratokonjunktivitisom i neurološkim simptomima. Uzročnik bolesti je DNK virus, koji pripada familiji Herpesviridae, subfamiliji
Gammaherpesvirinae, rodu Macavirus, koji obuhvata deset vrsta virusa. Najviše proučavani tipovi su alcelafinski herpesvirus 1 (AlHV-1) i ovčiji herpesvirus 2 (OvHV-2). Svaki tip virusa je prilagođen svom domaćinu, kod koga
ne dovodi do oboljenja, ali može izazvati simptome bolesti ili uginuća kod
drugih osetljivih vrsta. Druge životinjske vrste se zaraze ukoliko borave u istom
prostoru ili su na paši sa primarnim domaćinom. Najosetljivije životinje su
goveda, jeleni, antilope, žirafe, bizoni, a nekoliko slučajeva MKG je prijavljeno
kod jelena i losova u zoološkim vrtovima. Bolest je kod domaćih svinja dijagnostikovana u nekoliko zemalja. Infekcija se retko prenosi horizontalnim putem sa goveda na govedo, pa je za širenje infekcije i pojavu bolesti najbitnija
kohabitacija malih i velikih preživara. Goveda najčeće obole kada se drže
zajedno sa ovcama koje su gravidne ili su tek ojagnjene. Prijemčive su sve
starosne kategorije goveda, ali se MKG najčešće javlja kod jedinki starijih od
dve godine. MKG se pojavljuje u mnogim zemljama Afrike, Evrope, Azije i Amerike. Trenutno ne postoji adekvatna terapija ili komercijalna vakcina. Maligna
kataralna groznica nije zoonoza.",
publisher = "Beograd : Fakultet veterinarske medicine",
journal = "Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023",
title = "Maligna kataralna groznica – uloga ovaca i koza kao izvora infekcije za goveda",
pages = "182-190",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3114"
}

Bacić, D.,& Obrenović, S.. (2023). Maligna kataralna groznica – uloga ovaca i koza kao izvora infekcije za goveda. in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023
Beograd : Fakultet veterinarske medicine., 182-190.
https://hdl.handle.net/21.15107/rcub_veterinar_3114

Bacić D, Obrenović S. Maligna kataralna groznica – uloga ovaca i koza kao izvora infekcije za goveda. in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023. 2023;:182-190.
https://hdl.handle.net/21.15107/rcub_veterinar_3114 .

Bacić, Dragan, Obrenović, Sonja, "Maligna kataralna groznica – uloga ovaca i koza kao izvora infekcije za goveda" in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023 (2023):182-190,
https://hdl.handle.net/21.15107/rcub_veterinar_3114 .

TY  - CONF
AU  - Bacić, Dragan
AU  - Obrenović, Sonja
AU  - Potkonjak, Aleksandar
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3094
AB  - Listerioza je infektivno oboljenje ljudi, domaćih, divljih životinja,
riba, rakova i ptica koju izaziva gram - pozitivna bakterija, Listeria monocytogenes.
Preživari igraju glavnu ulogu u održavanju listerija, uz
pomoć kontinuiranog feko-oralnog ciklusa. Listerioza ovaca i goveda
se pojavljuje sporadično, učestalija je zimi i u rano proleće. Listerioza
preživara se javlja u obliku septikemije, encefalitisa, meningitisa, meningoencefalitisa,
keratokonjunktivitisa, gastroenteritisa, a dolazi i do
pojave abortusa, radjanja mrtvih plodova i perinatalne infekcije. Ovce
u latentnoj fazi bolesti predstavljaju kliconoše, jer izlučuju L. monocytogenes
preko mleka i fecesa. Mamarna infekcija može imati supklinički
tok, u toku kojeg klinički zdrave životinje izlučuju listerije tokom
dugog vremenskog perioda. Listerioza ljudi je relativno retka bolest sa
do 10 slučajeva na milion stanovnika godišnje u zavisnosti od zemalja
i regiona sveta. Iako je broj slučajeva mali, stopa smrtnost je jako
visoka (30%).
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023.
T1  - Listerioza preživara – stari, a novi problem u veterinarskoj i humanoj medicini
SP  - 55
EP  - 66
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3094
ER  - 

@conference{
author = "Bacić, Dragan and Obrenović, Sonja and Potkonjak, Aleksandar",
year = "2023",
abstract = "Listerioza je infektivno oboljenje ljudi, domaćih, divljih životinja,
riba, rakova i ptica koju izaziva gram - pozitivna bakterija, Listeria monocytogenes.
Preživari igraju glavnu ulogu u održavanju listerija, uz
pomoć kontinuiranog feko-oralnog ciklusa. Listerioza ovaca i goveda
se pojavljuje sporadično, učestalija je zimi i u rano proleće. Listerioza
preživara se javlja u obliku septikemije, encefalitisa, meningitisa, meningoencefalitisa,
keratokonjunktivitisa, gastroenteritisa, a dolazi i do
pojave abortusa, radjanja mrtvih plodova i perinatalne infekcije. Ovce
u latentnoj fazi bolesti predstavljaju kliconoše, jer izlučuju L. monocytogenes
preko mleka i fecesa. Mamarna infekcija može imati supklinički
tok, u toku kojeg klinički zdrave životinje izlučuju listerije tokom
dugog vremenskog perioda. Listerioza ljudi je relativno retka bolest sa
do 10 slučajeva na milion stanovnika godišnje u zavisnosti od zemalja
i regiona sveta. Iako je broj slučajeva mali, stopa smrtnost je jako
visoka (30%).",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023.",
title = "Listerioza preživara – stari, a novi problem u veterinarskoj i humanoj medicini",
pages = "55-66",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3094"
}

Bacić, D., Obrenović, S.,& Potkonjak, A.. (2023). Listerioza preživara – stari, a novi problem u veterinarskoj i humanoj medicini. in XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023.
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 55-66.
https://hdl.handle.net/21.15107/rcub_veterinar_3094

Bacić D, Obrenović S, Potkonjak A. Listerioza preživara – stari, a novi problem u veterinarskoj i humanoj medicini. in XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023.. 2023;:55-66.
https://hdl.handle.net/21.15107/rcub_veterinar_3094 .

Bacić, Dragan, Obrenović, Sonja, Potkonjak, Aleksandar, "Listerioza preživara – stari, a novi problem u veterinarskoj i humanoj medicini" in XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023. (2023):55-66,
https://hdl.handle.net/21.15107/rcub_veterinar_3094 .

TY  - CONF
AU  - Bojkovski, Jovan
AU  - Zdravković, Nemanja
AU  - Vakanjac, Slobodanka
AU  - Prodanović, Radiša
AU  - Arsić, Sveta
AU  - Nedić, Sreten
AU  - Vujanac, Ivan
AU  - Angjelovski, Branko
AU  - Dobrosavljević, Ivan
AU  - Pavlović, Ivan
AU  - Obrenović, Sonja
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2891
AB  - Intenzivna proizvodnja svinja na komercijalnim farmama nastoji da proizvede što veći broj odbijene prasadi odnosno tovljenika po krmači godišnje. Za postizanje ovakvih proizvodnih rezultata neophodno je uspostaviti visoku reproduktivnu efikasnost priplodnih životinja. Potrebna je adekvatna zdravstvena zaštita sa
dobrom organizacijom proizvodnje. Cilj rada je utvrđivanje reperoduktivne efikasnosti nerastova. Na jednoj komercijalnoj farmi smo pratili proizvodne rezultate
nerastova rase jorkšir, durok i holandski landras. U intenzivnom uzgoju svinja, više je validnih parametara kojima se može iskazati uspešnost odnosno profitabilnost proizvodnje, kao što su: broj živorođene ili odlučene prasadi, dnevni prirast,
dužina trajanja tova, broj neproduktivnih dana plotkinja i sl. Danas je uobičajeno
da se proizvodnja svinja na komercijalnim farmama prezentuje brojem odgajene prasadi odnosno isporučenih tovljenika po krmači u toku kalendarske godine.
AB  - Intensive production of pigs on commercial farms strives to produce the largest possible number of weaned piglets or fattening pigs per sow per year. To achieve such production results, it is necessary to establish a high reproductive efficiency of breeding animals. We need adequate health care with good organization of production. The aim of the article is to determine the reproductive efficiency
of boars. On a commercial farm, we monitored the production results of boars of the Yorkshire, Duroc and Dutch Landrace breed. In intensive pig breeding, there
are several valid parameters that can be used to show the success or profitability of production, such as: the number of live births or weaned piglets, daily gain,
duration of fattening, number of non-productive days of sows, etc. Today, it is customary to present pig production on commercial farms by the number of piglets
raised, i.e. delivered fatteners per sow during the calendar year.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022
T1  - Menadžment nerasta
SP  - 165
EP  - 169
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2891
ER  - 

@conference{
author = "Bojkovski, Jovan and Zdravković, Nemanja and Vakanjac, Slobodanka and Prodanović, Radiša and Arsić, Sveta and Nedić, Sreten and Vujanac, Ivan and Angjelovski, Branko and Dobrosavljević, Ivan and Pavlović, Ivan and Obrenović, Sonja",
year = "2022",
abstract = "Intenzivna proizvodnja svinja na komercijalnim farmama nastoji da proizvede što veći broj odbijene prasadi odnosno tovljenika po krmači godišnje. Za postizanje ovakvih proizvodnih rezultata neophodno je uspostaviti visoku reproduktivnu efikasnost priplodnih životinja. Potrebna je adekvatna zdravstvena zaštita sa
dobrom organizacijom proizvodnje. Cilj rada je utvrđivanje reperoduktivne efikasnosti nerastova. Na jednoj komercijalnoj farmi smo pratili proizvodne rezultate
nerastova rase jorkšir, durok i holandski landras. U intenzivnom uzgoju svinja, više je validnih parametara kojima se može iskazati uspešnost odnosno profitabilnost proizvodnje, kao što su: broj živorođene ili odlučene prasadi, dnevni prirast,
dužina trajanja tova, broj neproduktivnih dana plotkinja i sl. Danas je uobičajeno
da se proizvodnja svinja na komercijalnim farmama prezentuje brojem odgajene prasadi odnosno isporučenih tovljenika po krmači u toku kalendarske godine., Intensive production of pigs on commercial farms strives to produce the largest possible number of weaned piglets or fattening pigs per sow per year. To achieve such production results, it is necessary to establish a high reproductive efficiency of breeding animals. We need adequate health care with good organization of production. The aim of the article is to determine the reproductive efficiency
of boars. On a commercial farm, we monitored the production results of boars of the Yorkshire, Duroc and Dutch Landrace breed. In intensive pig breeding, there
are several valid parameters that can be used to show the success or profitability of production, such as: the number of live births or weaned piglets, daily gain,
duration of fattening, number of non-productive days of sows, etc. Today, it is customary to present pig production on commercial farms by the number of piglets
raised, i.e. delivered fatteners per sow during the calendar year.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022",
title = "Menadžment nerasta",
pages = "165-169",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2891"
}

Bojkovski, J., Zdravković, N., Vakanjac, S., Prodanović, R., Arsić, S., Nedić, S., Vujanac, I., Angjelovski, B., Dobrosavljević, I., Pavlović, I.,& Obrenović, S.. (2022). Menadžment nerasta. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 165-169.
https://hdl.handle.net/21.15107/rcub_veterinar_2891

Bojkovski J, Zdravković N, Vakanjac S, Prodanović R, Arsić S, Nedić S, Vujanac I, Angjelovski B, Dobrosavljević I, Pavlović I, Obrenović S. Menadžment nerasta. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022. 2022;:165-169.
https://hdl.handle.net/21.15107/rcub_veterinar_2891 .

Bojkovski, Jovan, Zdravković, Nemanja, Vakanjac, Slobodanka, Prodanović, Radiša, Arsić, Sveta, Nedić, Sreten, Vujanac, Ivan, Angjelovski, Branko, Dobrosavljević, Ivan, Pavlović, Ivan, Obrenović, Sonja, "Menadžment nerasta" in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022 (2022):165-169,
https://hdl.handle.net/21.15107/rcub_veterinar_2891 .

TY  - CONF
AU  - Obrenović, Sonja
AU  - Bojkovski, Jovan
AU  - Savić Radovanović, Radoslava
AU  - Grgić, Živoslav
AU  - Vakanjac, Slobodanka
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3190
AB  - Leptospiroza goveda je čest uzrok reproduktivnih poremećaja kod goveda
širom sveta. Goveda su primarni domaćini za serovar Hardjo koji obuhvata dva
serološki identična, ali genetski različita soja: Leptospira borgpetersenii serovar
Hardjo tip Hardjobovis i Leptospira interrogans serovar Hardjo tip Hardjoprajitno.
Oba soja su sposobna da kolonizuju i perzistiraju u urogenitalnom traktu zaraženih
životinja. Prenos se vrši direktnim kontaktom sa vodom ili hranom kontaminiranom
urinom inficiranih životinja ili transplacentarnom transmisijom. Navedeni
serovari obično izazivaju hronične ili supkliničke infekcije uz pojavu reproduktivnih
poremećaja i značajnih ekonomskih šteta širom sveta. Reproduktivni poremećaji
ispoljavaju se u vidu kasnih abortusa, rađanje mrtvih plodova, prevremenog porođaja,
rađenje avitalne teladi, padom mlečnosti i sterilitetom. Serovari za koje su
goveda slučajni domaćini (serogrupe Icterohaemorrhagiae, Canicola, Sejroe, Australis,
Grippotiphosa, Pomona), mogu izazvati akutnu infekciju praćenu febrilnim
stanjem, hemolitičkom anemijom, hemoglobinurijom, ikterusom i povremeno meningitisom
i uginućem. Infekcija navedenim serovarima kod gravidnih krava često
dovodi do visoke stope abortusa u zaraženom stadu, koji se javljaju nedeljama
nakon akutne faze bolesti. Pojava ikterusa je jedna od najznačajnijih kliničkih promena
prisutna kod abortusa izazvanog serovarima leptospira. Bolest je teško dijagnostikovati
zbog nedostatka patognomoničnih kliničkih znakova i problematične
laboratorijske dijagnostike.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022
T1  - Reproduktivni poremećaji goveda izazvani bakterijama roda leptospira
SP  - 155
EP  - 164
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3190
ER  - 

@conference{
author = "Obrenović, Sonja and Bojkovski, Jovan and Savić Radovanović, Radoslava and Grgić, Živoslav and Vakanjac, Slobodanka",
year = "2022",
abstract = "Leptospiroza goveda je čest uzrok reproduktivnih poremećaja kod goveda
širom sveta. Goveda su primarni domaćini za serovar Hardjo koji obuhvata dva
serološki identična, ali genetski različita soja: Leptospira borgpetersenii serovar
Hardjo tip Hardjobovis i Leptospira interrogans serovar Hardjo tip Hardjoprajitno.
Oba soja su sposobna da kolonizuju i perzistiraju u urogenitalnom traktu zaraženih
životinja. Prenos se vrši direktnim kontaktom sa vodom ili hranom kontaminiranom
urinom inficiranih životinja ili transplacentarnom transmisijom. Navedeni
serovari obično izazivaju hronične ili supkliničke infekcije uz pojavu reproduktivnih
poremećaja i značajnih ekonomskih šteta širom sveta. Reproduktivni poremećaji
ispoljavaju se u vidu kasnih abortusa, rađanje mrtvih plodova, prevremenog porođaja,
rađenje avitalne teladi, padom mlečnosti i sterilitetom. Serovari za koje su
goveda slučajni domaćini (serogrupe Icterohaemorrhagiae, Canicola, Sejroe, Australis,
Grippotiphosa, Pomona), mogu izazvati akutnu infekciju praćenu febrilnim
stanjem, hemolitičkom anemijom, hemoglobinurijom, ikterusom i povremeno meningitisom
i uginućem. Infekcija navedenim serovarima kod gravidnih krava često
dovodi do visoke stope abortusa u zaraženom stadu, koji se javljaju nedeljama
nakon akutne faze bolesti. Pojava ikterusa je jedna od najznačajnijih kliničkih promena
prisutna kod abortusa izazvanog serovarima leptospira. Bolest je teško dijagnostikovati
zbog nedostatka patognomoničnih kliničkih znakova i problematične
laboratorijske dijagnostike.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022",
title = "Reproduktivni poremećaji goveda izazvani bakterijama roda leptospira",
pages = "155-164",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3190"
}

Obrenović, S., Bojkovski, J., Savić Radovanović, R., Grgić, Ž.,& Vakanjac, S.. (2022). Reproduktivni poremećaji goveda izazvani bakterijama roda leptospira. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 155-164.
https://hdl.handle.net/21.15107/rcub_veterinar_3190

Obrenović S, Bojkovski J, Savić Radovanović R, Grgić Ž, Vakanjac S. Reproduktivni poremećaji goveda izazvani bakterijama roda leptospira. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022. 2022;:155-164.
https://hdl.handle.net/21.15107/rcub_veterinar_3190 .

Obrenović, Sonja, Bojkovski, Jovan, Savić Radovanović, Radoslava, Grgić, Živoslav, Vakanjac, Slobodanka, "Reproduktivni poremećaji goveda izazvani bakterijama roda leptospira" in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022 (2022):155-164,
https://hdl.handle.net/21.15107/rcub_veterinar_3190 .

TY  - JOUR
AU  - Nišavić, Jakov
AU  - Milić, Nenad
AU  - Radalj, Andrea
AU  - Krnjaić, Dejan
AU  - Milićević, Dragan
AU  - Knežević, Aleksandra
AU  - Radojičić, Marina
AU  - Obrenović, Sonja
AU  - Ćosić, Milivoje
AU  - Tešović, Bojana
AU  - Benković, Damir
AU  - Živulj Aleksandar
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2044
AB  - Porcine parvoviruses (PPVs) are diverse and persistently evolving viruses found in domestic pigs and wild boars. Porcine parvovirus 1 (PPV1) causes reproductive problems in adult animals, although the veterinary relevance of PPV2, PPV3, and PPV4 has not been clarified. The detection and sequence analysis of PPVs circulating in wild boar populations in Serbia was performed to determine their phylogenetic relationships and prevalence in 122 organ samples collected during 2018. The DNA of PPV1, PPV2, and PPV3 was detected in 56.6% of the examined samples, whilst PPV4 was not identified. Overall, PPV3 was the most prevalent in 69.6% of the positive samples, followed by PPV1 in 63.8%, and PPV2 in 21.7% samples. Single infections were more common, although concurrent infections were confirmed in 34.8% samples for two, and 10.1% samples for three viruses. Sequence analysis of wild boar PPV1 showed no significant nucleotide differences from domestic pig PPV1 strains detected in Europe and the USA, however separate clustering from strains from China and the NADL-2 strain was demonstrated. Examination of the selected PPV2 sequences might suggest a certain geographical distribution of genetically diverse PPV2 strains considering high similarities to the strains from neighboring countries, and variability in comparison with other reported PPV2 sequences from different parts of the world. Wild boar PPV3 sequences clustered separately from most of the strains detected in wild boars, as well as the original porcine hokovirus strain. It is further noted that genetically different PPV3 strains circulate amongst Serbian domestic pigs and wild boars.
AB  - Parvovirusi svinja predstavljaju genetski različite viruse koji izazivaju infekcije doma-ćih i divljih svinja. Parvovirus svinja 1 (PPV1) dovodi do pojave reproduktivnih pro-blema  kod  odraslih  jedinki,  dok  klinički  značaj  PPV2,  PPV3  i  PPV4  još  uvek  nije  u  potpunosti  razjašnjen.  Izvršena  je  detekcija  i  analiza  genetskih  sekvenci  parvovirusa  koji  cirkulišu  u  populaciji  divljih  svinja  u  Srbiji  u  cilju  njihove  fi  logenetske  analize  i  određivanja zastupljenosti u ukupno 122 uzorka organa prikupljenih tokom 2018. go-dine. Prisustvo DNK PPV1, PPV2 i PPV3 detektovano je u 56,6% ispitanih uzoraka, pri čemu  prisustvo  PPV4  nije  utvrđeno.  Među  pozitivnim  uzorcima,  PPV3  je  pro-centualno najzastupljeniji virus detektovan u 69,6%, dok je prisustvo  PPV1 i PPV2 utvrđeno u 63,8%, odnosno u 21,7% pozitivnih uzoraka. Infekcije jednim virusom su češće identifi kovane, međutim, prisustvo mešovitih infekcija sa dva, odnosno tri par-vovirusa zabeleženo je u 34,8% i 10,1% uzoraka. Analizom genetskih sekvenci PPV1 detektovanih kod divljih svinja nisu utvrđene značajnije razlike u odnosu na analogne sekvence PPV1 poreklom od domaćih svinja iz Evrope i SAD, međutim zabeleženo je izdvajanje u zaseban klaster u odnosu na kineske sojeve virusa i soj NADL-2. Ispi-tivanjem sekvenci PPV2 utvrđena je izvesna geografska distribucija genetski različitih sojeva navedenog virusa s obzirom na njihovu veliku sličnost sa sojevima virusa iz su-sednih zemalja. Sekvence PPV3 detektovanih kod divljih svinja su se na fi logenetskom stablu izdvajale u zaseban klaster u odnosu na većinu dostupnih sekvenci navedenog virusa detektovanih kod divljih svinja. Pored toga, zabeleženo je da genetski različiti sojevi PPV3 cirkulišu u populacijama divljih i domaćih svinja u Srbiji.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia
T1  - Genetska analiza i distribucija parvovirusa (ppvs) detektovanih u organima divljih svinja u Srbiji
VL  - 71
IS  - 1
SP  - 32
EP  - 46
DO  - 10.2478/acve-2021-0003
ER  - 

@article{
author = "Nišavić, Jakov and Milić, Nenad and Radalj, Andrea and Krnjaić, Dejan and Milićević, Dragan and Knežević, Aleksandra and Radojičić, Marina and Obrenović, Sonja and Ćosić, Milivoje and Tešović, Bojana and Benković, Damir and Živulj Aleksandar",
year = "2021",
abstract = "Porcine parvoviruses (PPVs) are diverse and persistently evolving viruses found in domestic pigs and wild boars. Porcine parvovirus 1 (PPV1) causes reproductive problems in adult animals, although the veterinary relevance of PPV2, PPV3, and PPV4 has not been clarified. The detection and sequence analysis of PPVs circulating in wild boar populations in Serbia was performed to determine their phylogenetic relationships and prevalence in 122 organ samples collected during 2018. The DNA of PPV1, PPV2, and PPV3 was detected in 56.6% of the examined samples, whilst PPV4 was not identified. Overall, PPV3 was the most prevalent in 69.6% of the positive samples, followed by PPV1 in 63.8%, and PPV2 in 21.7% samples. Single infections were more common, although concurrent infections were confirmed in 34.8% samples for two, and 10.1% samples for three viruses. Sequence analysis of wild boar PPV1 showed no significant nucleotide differences from domestic pig PPV1 strains detected in Europe and the USA, however separate clustering from strains from China and the NADL-2 strain was demonstrated. Examination of the selected PPV2 sequences might suggest a certain geographical distribution of genetically diverse PPV2 strains considering high similarities to the strains from neighboring countries, and variability in comparison with other reported PPV2 sequences from different parts of the world. Wild boar PPV3 sequences clustered separately from most of the strains detected in wild boars, as well as the original porcine hokovirus strain. It is further noted that genetically different PPV3 strains circulate amongst Serbian domestic pigs and wild boars., Parvovirusi svinja predstavljaju genetski različite viruse koji izazivaju infekcije doma-ćih i divljih svinja. Parvovirus svinja 1 (PPV1) dovodi do pojave reproduktivnih pro-blema  kod  odraslih  jedinki,  dok  klinički  značaj  PPV2,  PPV3  i  PPV4  još  uvek  nije  u  potpunosti  razjašnjen.  Izvršena  je  detekcija  i  analiza  genetskih  sekvenci  parvovirusa  koji  cirkulišu  u  populaciji  divljih  svinja  u  Srbiji  u  cilju  njihove  fi  logenetske  analize  i  određivanja zastupljenosti u ukupno 122 uzorka organa prikupljenih tokom 2018. go-dine. Prisustvo DNK PPV1, PPV2 i PPV3 detektovano je u 56,6% ispitanih uzoraka, pri čemu  prisustvo  PPV4  nije  utvrđeno.  Među  pozitivnim  uzorcima,  PPV3  je  pro-centualno najzastupljeniji virus detektovan u 69,6%, dok je prisustvo  PPV1 i PPV2 utvrđeno u 63,8%, odnosno u 21,7% pozitivnih uzoraka. Infekcije jednim virusom su češće identifi kovane, međutim, prisustvo mešovitih infekcija sa dva, odnosno tri par-vovirusa zabeleženo je u 34,8% i 10,1% uzoraka. Analizom genetskih sekvenci PPV1 detektovanih kod divljih svinja nisu utvrđene značajnije razlike u odnosu na analogne sekvence PPV1 poreklom od domaćih svinja iz Evrope i SAD, međutim zabeleženo je izdvajanje u zaseban klaster u odnosu na kineske sojeve virusa i soj NADL-2. Ispi-tivanjem sekvenci PPV2 utvrđena je izvesna geografska distribucija genetski različitih sojeva navedenog virusa s obzirom na njihovu veliku sličnost sa sojevima virusa iz su-sednih zemalja. Sekvence PPV3 detektovanih kod divljih svinja su se na fi logenetskom stablu izdvajale u zaseban klaster u odnosu na većinu dostupnih sekvenci navedenog virusa detektovanih kod divljih svinja. Pored toga, zabeleženo je da genetski različiti sojevi PPV3 cirkulišu u populacijama divljih i domaćih svinja u Srbiji.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia, Genetska analiza i distribucija parvovirusa (ppvs) detektovanih u organima divljih svinja u Srbiji",
volume = "71",
number = "1",
pages = "32-46",
doi = "10.2478/acve-2021-0003"
}

Nišavić, J., Milić, N., Radalj, A., Krnjaić, D., Milićević, D., Knežević, A., Radojičić, M., Obrenović, S., Ćosić, M., Tešović, B., Benković, D.,& Živulj Aleksandar. (2021). Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 71(1), 32-46.
https://doi.org/10.2478/acve-2021-0003

Nišavić J, Milić N, Radalj A, Krnjaić D, Milićević D, Knežević A, Radojičić M, Obrenović S, Ćosić M, Tešović B, Benković D, Živulj Aleksandar. Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia. in Acta Veterinaria-Beograd. 2021;71(1):32-46.
doi:10.2478/acve-2021-0003 .

Nišavić, Jakov, Milić, Nenad, Radalj, Andrea, Krnjaić, Dejan, Milićević, Dragan, Knežević, Aleksandra, Radojičić, Marina, Obrenović, Sonja, Ćosić, Milivoje, Tešović, Bojana, Benković, Damir, Živulj Aleksandar, "Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia" in Acta Veterinaria-Beograd, 71, no. 1 (2021):32-46,
https://doi.org/10.2478/acve-2021-0003 . .

TY  - CONF
AU  - Bacić, Dragan
AU  - Obrenović, Sonja
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3198
AB  - Kuga malih preživara (KMP) je veoma kontagiozno virusno oboljenje ovaca,
koza i drugih, divljih malih preživara, koje se endemski pojavljuje u Africi,
na Bliskom Istoku i u velikim regionima Azije. Smatra se da je ovo oboljenje
glavna prepreka razvoju stočarstva širom sveta, zbog toga što ima negativne
socio-ekonomske posledice po egzistenciju najugroženijih ruralnih područja
zemalja u razvoju. Na sastanku svetske skupštine OIE-a koja je održana u
Abidžanu, Obala Slonovače 2015 godine, eksperti iz 70 zemalja su usvojili Rezoluciju
br. 25, koja je izglasana na 84. Generalnoj sednici OIE. U skladu sa
preporukama konferencije, Svetska organizacija za zdravlje životinja (OIE) i
Organizacija za hranu i poljoprivredu (FAO) su formirale zajednički tim, čiji je
zadatak, nadgledanje i sprovođenje mera koje imaju za cilj eradikaciju bolesti
na globalnom nivou, do 2030. godine. U poslednjih 15 godina došlo je do značajnog
širenja bolesti na region severne. Afrike, Maroko (2015) i Tunis (2016).
Bolest je prisutna nekoliko decenija u Turskoj, a prijavljeni su slučajevi u Gruziji
2016. i 2018. godine u Bugarskoj. Kina je kugu malih peživara prvi put prijavila
2007. godine. Bolest se nalazi na listi OIE i obavezna je za prijavljivanje. KMP
nije zoonoza, ali je pretnja međunarodnoj trgovini životinjama i uzrokuje velike
ekonomske gubitke. Za sprečavanje bolesti dostupna je atenuirana vakcina
koja nije registrovana u našoj zemlji.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - Treći simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 25 - 27. jun 2021
T1  - Kuga malih preživara – realna pretnja za Srbiju i region
SP  - 343
EP  - 351
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3198
ER  - 

@conference{
author = "Bacić, Dragan and Obrenović, Sonja",
year = "2021",
abstract = "Kuga malih preživara (KMP) je veoma kontagiozno virusno oboljenje ovaca,
koza i drugih, divljih malih preživara, koje se endemski pojavljuje u Africi,
na Bliskom Istoku i u velikim regionima Azije. Smatra se da je ovo oboljenje
glavna prepreka razvoju stočarstva širom sveta, zbog toga što ima negativne
socio-ekonomske posledice po egzistenciju najugroženijih ruralnih područja
zemalja u razvoju. Na sastanku svetske skupštine OIE-a koja je održana u
Abidžanu, Obala Slonovače 2015 godine, eksperti iz 70 zemalja su usvojili Rezoluciju
br. 25, koja je izglasana na 84. Generalnoj sednici OIE. U skladu sa
preporukama konferencije, Svetska organizacija za zdravlje životinja (OIE) i
Organizacija za hranu i poljoprivredu (FAO) su formirale zajednički tim, čiji je
zadatak, nadgledanje i sprovođenje mera koje imaju za cilj eradikaciju bolesti
na globalnom nivou, do 2030. godine. U poslednjih 15 godina došlo je do značajnog
širenja bolesti na region severne. Afrike, Maroko (2015) i Tunis (2016).
Bolest je prisutna nekoliko decenija u Turskoj, a prijavljeni su slučajevi u Gruziji
2016. i 2018. godine u Bugarskoj. Kina je kugu malih peživara prvi put prijavila
2007. godine. Bolest se nalazi na listi OIE i obavezna je za prijavljivanje. KMP
nije zoonoza, ali je pretnja međunarodnoj trgovini životinjama i uzrokuje velike
ekonomske gubitke. Za sprečavanje bolesti dostupna je atenuirana vakcina
koja nije registrovana u našoj zemlji.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "Treći simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 25 - 27. jun 2021",
title = "Kuga malih preživara – realna pretnja za Srbiju i region",
pages = "343-351",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3198"
}

Bacić, D.,& Obrenović, S.. (2021). Kuga malih preživara – realna pretnja za Srbiju i region. in Treći simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 25 - 27. jun 2021
Beograd : Srpsko veterinarsko društvo., 343-351.
https://hdl.handle.net/21.15107/rcub_veterinar_3198

Bacić D, Obrenović S. Kuga malih preživara – realna pretnja za Srbiju i region. in Treći simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 25 - 27. jun 2021. 2021;:343-351.
https://hdl.handle.net/21.15107/rcub_veterinar_3198 .

Bacić, Dragan, Obrenović, Sonja, "Kuga malih preživara – realna pretnja za Srbiju i region" in Treći simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 25 - 27. jun 2021 (2021):343-351,
https://hdl.handle.net/21.15107/rcub_veterinar_3198 .

TY  - JOUR
AU  - Bacić, Dragan
AU  - Obrenović, Sonja
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3444
PB  - Banja Luka : PI Veterinary institute of Republic of Srpska 'Dr Vaso Butozan'
T2  - Veterinary Journal of Republic of Srpska
T1  - Virusni enteritisi pasa – stari i novi patogeni
VL  - 21
IS  - 1-2
SP  - 170
EP  - 177
DO  - 10.7251/VETJSR2101170B
ER  - 

@article{
author = "Bacić, Dragan and Obrenović, Sonja",
year = "2021",
publisher = "Banja Luka : PI Veterinary institute of Republic of Srpska 'Dr Vaso Butozan'",
journal = "Veterinary Journal of Republic of Srpska",
title = "Virusni enteritisi pasa – stari i novi patogeni",
volume = "21",
number = "1-2",
pages = "170-177",
doi = "10.7251/VETJSR2101170B"
}

Bacić, D.,& Obrenović, S.. (2021). Virusni enteritisi pasa – stari i novi patogeni. in Veterinary Journal of Republic of Srpska
Banja Luka : PI Veterinary institute of Republic of Srpska 'Dr Vaso Butozan'., 21(1-2), 170-177.
https://doi.org/10.7251/VETJSR2101170B

Bacić D, Obrenović S. Virusni enteritisi pasa – stari i novi patogeni. in Veterinary Journal of Republic of Srpska. 2021;21(1-2):170-177.
doi:10.7251/VETJSR2101170B .

Bacić, Dragan, Obrenović, Sonja, "Virusni enteritisi pasa – stari i novi patogeni" in Veterinary Journal of Republic of Srpska, 21, no. 1-2 (2021):170-177,
https://doi.org/10.7251/VETJSR2101170B . .

TY  - JOUR
AU  - Laušević, Dejan
AU  - Ilić, Tamara
AU  - Nenadović, Katarina
AU  - Bacić, Dragan
AU  - Obrenović, Sonja
PY  - 2020
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1822
AB  - Due to an unfortunate error during the processing of the article, the given name and family name of all authors were interchanged. The original article has been corrected.
PB  - Springer International Publishing Ag, Cham
T2  - Acta Parasitologica
T1  - Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro
VL  - 65
IS  - 1
SP  - 271
EP  - 271
DO  - 10.2478/s11686-019-00152-7
ER  - 

@article{
author = "Laušević, Dejan and Ilić, Tamara and Nenadović, Katarina and Bacić, Dragan and Obrenović, Sonja",
year = "2020",
abstract = "Due to an unfortunate error during the processing of the article, the given name and family name of all authors were interchanged. The original article has been corrected.",
publisher = "Springer International Publishing Ag, Cham",
journal = "Acta Parasitologica",
title = "Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro",
volume = "65",
number = "1",
pages = "271-271",
doi = "10.2478/s11686-019-00152-7"
}

Laušević, D., Ilić, T., Nenadović, K., Bacić, D.,& Obrenović, S.. (2020). Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro. in Acta Parasitologica
Springer International Publishing Ag, Cham., 65(1), 271-271.
https://doi.org/10.2478/s11686-019-00152-7

Laušević D, Ilić T, Nenadović K, Bacić D, Obrenović S. Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro. in Acta Parasitologica. 2020;65(1):271-271.
doi:10.2478/s11686-019-00152-7 .

Laušević, Dejan, Ilić, Tamara, Nenadović, Katarina, Bacić, Dragan, Obrenović, Sonja, "Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro" in Acta Parasitologica, 65, no. 1 (2020):271-271,
https://doi.org/10.2478/s11686-019-00152-7 . .

TY  - JOUR
AU  - Manić, Marija
AU  - Stojiljković, Marko
AU  - Petrović, Milos
AU  - Nišavić, Jakov
AU  - Bacić, Dragan
AU  - Petrović, Tamaš
AU  - Vidanović, Dejan
AU  - Obrenović, Sonja
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1792
AB  - Lumpy skin disease (LSD) is an infectious disease of cattle caused by virus of the Capripoxvirus genus (LSDV), family Poxviridae. Until 2015, it had not appeared in the Balkans. In June 2016, LSD spread throughout Serbia. This study analyses the first LSD occurrence, epizootic features, applied diagnostic procedures and control measures in five districts in south-east Serbia (Pcinja, Jablanica, Pirot, Toplica and Nisava). In total, there were 225 LSD outbreaks reported in Serbia, out of which 189 (84%) were located in the study area. The highest number of outbreaks was registered in Pcinja district (169), where LSD was first registered. The median distance and time between the nearest previous outbreak sites were calculated (4.32 km and 9 days). The median altitude of outbreak locations was 992 m with more than 90% above 500 m (p <= 0.001). The average herd morbidity rate in the study area was 13.6% and the herd mortality rate was recorded only in Pcinja (0.5%) and Jablanica (1.6%) districts. Samples taken from the cattle suspected to LSD were subjected to real time PCR analysis. Out of 233 samples tested for LSDV 132 (56.7%) were positive. The LSDV genome was identified in skin nodules (85.4%), blood (72.7%) and nasal swabs (62.5%). Phylogenetic analysis indicated that the LSDV strain circulating in Serbia fell within the cluster of field LSDV found worldwide. In response to the LSD epizootic, animal trade and movement were prohibited, complete stamping out, disinfection, disinsection and an entire bovine population vaccination using the homologous Neethling live attenuated vaccine (OBP, South Africa) were conducted. A month and a half after the completion of the vaccination campaign, the LSD epizootic was stopped, and no new cases have been reported since.
PB  - Wiley, Hoboken
T2  - Transboundary and Emerging Diseases
T1  - Epizootic features and control measures for lumpy skin disease in south-east Serbia in 2016
VL  - 66
IS  - 5
SP  - 2087
EP  - 2099
DO  - 10.1111/tbed.13261
ER  - 

@article{
author = "Manić, Marija and Stojiljković, Marko and Petrović, Milos and Nišavić, Jakov and Bacić, Dragan and Petrović, Tamaš and Vidanović, Dejan and Obrenović, Sonja",
year = "2019",
abstract = "Lumpy skin disease (LSD) is an infectious disease of cattle caused by virus of the Capripoxvirus genus (LSDV), family Poxviridae. Until 2015, it had not appeared in the Balkans. In June 2016, LSD spread throughout Serbia. This study analyses the first LSD occurrence, epizootic features, applied diagnostic procedures and control measures in five districts in south-east Serbia (Pcinja, Jablanica, Pirot, Toplica and Nisava). In total, there were 225 LSD outbreaks reported in Serbia, out of which 189 (84%) were located in the study area. The highest number of outbreaks was registered in Pcinja district (169), where LSD was first registered. The median distance and time between the nearest previous outbreak sites were calculated (4.32 km and 9 days). The median altitude of outbreak locations was 992 m with more than 90% above 500 m (p <= 0.001). The average herd morbidity rate in the study area was 13.6% and the herd mortality rate was recorded only in Pcinja (0.5%) and Jablanica (1.6%) districts. Samples taken from the cattle suspected to LSD were subjected to real time PCR analysis. Out of 233 samples tested for LSDV 132 (56.7%) were positive. The LSDV genome was identified in skin nodules (85.4%), blood (72.7%) and nasal swabs (62.5%). Phylogenetic analysis indicated that the LSDV strain circulating in Serbia fell within the cluster of field LSDV found worldwide. In response to the LSD epizootic, animal trade and movement were prohibited, complete stamping out, disinfection, disinsection and an entire bovine population vaccination using the homologous Neethling live attenuated vaccine (OBP, South Africa) were conducted. A month and a half after the completion of the vaccination campaign, the LSD epizootic was stopped, and no new cases have been reported since.",
publisher = "Wiley, Hoboken",
journal = "Transboundary and Emerging Diseases",
title = "Epizootic features and control measures for lumpy skin disease in south-east Serbia in 2016",
volume = "66",
number = "5",
pages = "2087-2099",
doi = "10.1111/tbed.13261"
}

Manić, M., Stojiljković, M., Petrović, M., Nišavić, J., Bacić, D., Petrović, T., Vidanović, D.,& Obrenović, S.. (2019). Epizootic features and control measures for lumpy skin disease in south-east Serbia in 2016. in Transboundary and Emerging Diseases
Wiley, Hoboken., 66(5), 2087-2099.
https://doi.org/10.1111/tbed.13261

Manić M, Stojiljković M, Petrović M, Nišavić J, Bacić D, Petrović T, Vidanović D, Obrenović S. Epizootic features and control measures for lumpy skin disease in south-east Serbia in 2016. in Transboundary and Emerging Diseases. 2019;66(5):2087-2099.
doi:10.1111/tbed.13261 .

Manić, Marija, Stojiljković, Marko, Petrović, Milos, Nišavić, Jakov, Bacić, Dragan, Petrović, Tamaš, Vidanović, Dejan, Obrenović, Sonja, "Epizootic features and control measures for lumpy skin disease in south-east Serbia in 2016" in Transboundary and Emerging Diseases, 66, no. 5 (2019):2087-2099,
https://doi.org/10.1111/tbed.13261 . .

TY  - JOUR
AU  - Laušević, Dejan
AU  - Ilić, Tamara
AU  - Nenadović, Katarina
AU  - Bacić, Dragan
AU  - Obrenović, Sonja
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1729
AB  - Purpose The incidence of vector-borne zoonoses has been increasing in Europe as a result of global climate change, and rickettsioses are a significant etiologic entity among these infections. The objective of this study was to investigate the seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in dogs in Montenegro. Methods The seroepidemiological study covered 259 dogs, of which 155 were owned dogs suspected of infection with agents of rickettsial aetiology from the continental (Podgorica) or five coastal municipalities of Montenegro (Budva, Herceg Novi, Kotor, Ulcinj and Bar), and 104 dogs were from a public shelter in Podgorica. The presence of specific IgG antibodies against R. conorii was analysed using a commercial indirect enzyme-linked immunosorbent assay (ELISA) test, and the presence of antibodies against E. canis and C. burnetii was analysed using commercial indirect immunofluorescence tests (IFAT). Results Seroprevalences of 73.36, 19.3 and 1.16% were determined for R. conorii, E. canis and C. burnetii, respectively. R. conorii was significantly more prevalent (chi(2) = 14.53; p < 0.001) in owned dogs (81.93%) than in dogs from the public shelter (60.6%), while E. canis was more prevalent (chi(2) = 12.31; p < 0.001) in dogs from the public shelter (29.81%) than in owned dogs (12.26%). Coinfection with two pathogens was determined in 40 (15.44%) dogs, and the prevalence of R. conorii/E. canis (chi(2) = 4.23; p < 0.05) was greater in dogs from the public shelter (20.19%) than in owned dogs (10.97%). Conclusion The prevailing evidence from this study shows that dogs from Montenegro are exposed to pathogens of veterinary and public health importance. This calls for the One Health approach to sensitise the public on the risks of zoonoses from dogs and to formulate policies and strategies to mitigate their spread and safeguard public health.
PB  - Springer International Publishing Ag, Cham
T2  - Acta Parasitologica
T1  - Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro
VL  - 64
IS  - 4
SP  - 769
EP  - 778
DO  - 10.2478/s11686-019-00098-w
ER  - 

@article{
author = "Laušević, Dejan and Ilić, Tamara and Nenadović, Katarina and Bacić, Dragan and Obrenović, Sonja",
year = "2019",
abstract = "Purpose The incidence of vector-borne zoonoses has been increasing in Europe as a result of global climate change, and rickettsioses are a significant etiologic entity among these infections. The objective of this study was to investigate the seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in dogs in Montenegro. Methods The seroepidemiological study covered 259 dogs, of which 155 were owned dogs suspected of infection with agents of rickettsial aetiology from the continental (Podgorica) or five coastal municipalities of Montenegro (Budva, Herceg Novi, Kotor, Ulcinj and Bar), and 104 dogs were from a public shelter in Podgorica. The presence of specific IgG antibodies against R. conorii was analysed using a commercial indirect enzyme-linked immunosorbent assay (ELISA) test, and the presence of antibodies against E. canis and C. burnetii was analysed using commercial indirect immunofluorescence tests (IFAT). Results Seroprevalences of 73.36, 19.3 and 1.16% were determined for R. conorii, E. canis and C. burnetii, respectively. R. conorii was significantly more prevalent (chi(2) = 14.53; p < 0.001) in owned dogs (81.93%) than in dogs from the public shelter (60.6%), while E. canis was more prevalent (chi(2) = 12.31; p < 0.001) in dogs from the public shelter (29.81%) than in owned dogs (12.26%). Coinfection with two pathogens was determined in 40 (15.44%) dogs, and the prevalence of R. conorii/E. canis (chi(2) = 4.23; p < 0.05) was greater in dogs from the public shelter (20.19%) than in owned dogs (10.97%). Conclusion The prevailing evidence from this study shows that dogs from Montenegro are exposed to pathogens of veterinary and public health importance. This calls for the One Health approach to sensitise the public on the risks of zoonoses from dogs and to formulate policies and strategies to mitigate their spread and safeguard public health.",
publisher = "Springer International Publishing Ag, Cham",
journal = "Acta Parasitologica",
title = "Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro",
volume = "64",
number = "4",
pages = "769-778",
doi = "10.2478/s11686-019-00098-w"
}

Laušević, D., Ilić, T., Nenadović, K., Bacić, D.,& Obrenović, S.. (2019). Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro. in Acta Parasitologica
Springer International Publishing Ag, Cham., 64(4), 769-778.
https://doi.org/10.2478/s11686-019-00098-w

Laušević D, Ilić T, Nenadović K, Bacić D, Obrenović S. Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro. in Acta Parasitologica. 2019;64(4):769-778.
doi:10.2478/s11686-019-00098-w .

Laušević, Dejan, Ilić, Tamara, Nenadović, Katarina, Bacić, Dragan, Obrenović, Sonja, "Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro" in Acta Parasitologica, 64, no. 4 (2019):769-778,
https://doi.org/10.2478/s11686-019-00098-w . .

TY  - CONF
AU  - Bojkovski, Jovan
AU  - Prodanović-Radulović, Jasna
AU  - Vakanjac, Slobodanka
AU  - Obrenović, Sonja
AU  - Becskei, Zsolt
AU  - Stanišić, Ljubodrag
AU  - Maletić, Milan
AU  - Đurić, Miloje
AU  - Dobrosavljević, Ivan
PY  - 2018
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2816
AB  - Cirkovirusne infekcije svinja predstavljaju zdravstveni problem, novijeg su
datuma i danas zaokupljaju pažnju velikog broja svetskih istraživača. Problem cirkovirusne
infekcije i danas predstavlja značajnu nepoznanicu odnosno prazninu
u veterinarskom saznanju, kako u svetu, tako i u domaćoj stručnoj javnosti. Bolest
izazvana svinjskim cirkovirusom tipa 2 (PCV-2) je prvi put opisana još 1997.
godine u Kanadi i relativno brzo se proširila po svetu. Od opštih preventivnih mera,
važnu ulogu imaju primena karantina, principa “sve napolje sve unutra”, sistema
pranja i dezinfekcije, kao i adekvatan odmor objekta. Danas je vakcinacija
značajna i veoma aktuelna metoda kontrole cirkovirusnih infekcija u svinjarskoj
proizvodnji.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 9. naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 11-14. oktobar 2018.
T1  - Cirkovirusne infekcije svinja na komercijalnim farmama
SP  - 131
EP  - 136
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2816
ER  - 

@conference{
author = "Bojkovski, Jovan and Prodanović-Radulović, Jasna and Vakanjac, Slobodanka and Obrenović, Sonja and Becskei, Zsolt and Stanišić, Ljubodrag and Maletić, Milan and Đurić, Miloje and Dobrosavljević, Ivan",
year = "2018",
abstract = "Cirkovirusne infekcije svinja predstavljaju zdravstveni problem, novijeg su
datuma i danas zaokupljaju pažnju velikog broja svetskih istraživača. Problem cirkovirusne
infekcije i danas predstavlja značajnu nepoznanicu odnosno prazninu
u veterinarskom saznanju, kako u svetu, tako i u domaćoj stručnoj javnosti. Bolest
izazvana svinjskim cirkovirusom tipa 2 (PCV-2) je prvi put opisana još 1997.
godine u Kanadi i relativno brzo se proširila po svetu. Od opštih preventivnih mera,
važnu ulogu imaju primena karantina, principa “sve napolje sve unutra”, sistema
pranja i dezinfekcije, kao i adekvatan odmor objekta. Danas je vakcinacija
značajna i veoma aktuelna metoda kontrole cirkovirusnih infekcija u svinjarskoj
proizvodnji.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "9. naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 11-14. oktobar 2018.",
title = "Cirkovirusne infekcije svinja na komercijalnim farmama",
pages = "131-136",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2816"
}

Bojkovski, J., Prodanović-Radulović, J., Vakanjac, S., Obrenović, S., Becskei, Z., Stanišić, L., Maletić, M., Đurić, M.,& Dobrosavljević, I.. (2018). Cirkovirusne infekcije svinja na komercijalnim farmama. in 9. naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 11-14. oktobar 2018.
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 131-136.
https://hdl.handle.net/21.15107/rcub_veterinar_2816

Bojkovski J, Prodanović-Radulović J, Vakanjac S, Obrenović S, Becskei Z, Stanišić L, Maletić M, Đurić M, Dobrosavljević I. Cirkovirusne infekcije svinja na komercijalnim farmama. in 9. naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 11-14. oktobar 2018.. 2018;:131-136.
https://hdl.handle.net/21.15107/rcub_veterinar_2816 .

Bojkovski, Jovan, Prodanović-Radulović, Jasna, Vakanjac, Slobodanka, Obrenović, Sonja, Becskei, Zsolt, Stanišić, Ljubodrag, Maletić, Milan, Đurić, Miloje, Dobrosavljević, Ivan, "Cirkovirusne infekcije svinja na komercijalnim farmama" in 9. naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 11-14. oktobar 2018. (2018):131-136,
https://hdl.handle.net/21.15107/rcub_veterinar_2816 .

TY  - JOUR
AU  - Vakanjac, Slobodanka
AU  - Maletić, Milan
AU  - Pavlović, Miloš
AU  - Obrenović, Sonja
AU  - Bojkovski, Jovan
AU  - Magaš, Vladimir
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2158
AB  - Zapaljenje vimena ili mastitis kod krava je akutno ili hronično zapaljenje izvodnih
kanala, parenhima ili intersticijuma jedne ili više četvrti vimena krava. Mastitis
se definiše kao odgovor mlečne žlezde na prisustvo mikroorganizama. Mastitisi
predstavljaju veliki zdravstveni i ekonomski problem u zapatima visokomlečnih
krava, a mogu se javiti u kliničkoj formi (klinički mastitis) sa raširenošću 1–3% i u
subkliničkoj formi (subklinički mastitis) sa raširenošću više od 30%. Staphylococcus
aureus izaziva teške akutne mastitise veoma često sa promenom opšteg stanja, ali i
subkliničke forme mastitisa. Terapija ovog mastitisa ne daje uvek zadovoljavajuće
rezultate, pa je vakcinacija jedan od mogućih pristupa u rešavanju ovog problema.
Stafilokoke su veoma slabi antigeni, što dodatno onemogućava i otežava pronalazak
efikasne vakcine. U literaturi su opisani različiti pristupi pripreme vakcine protiv
mastitisa izazvanog S. aureusom. Vakcina može da sadrži inaktivisane bakterije
S. aureus, alfa i beta toksoide, proteina A i fibronectin-binding protein kao moguće
antigene u aktivaciji aktivnog imunološkog odgovora. Imunizovanje mlečne žlezde
gde se kao antigen koristi inkorporisan lizat S. aureus u biodegradabilne parikule koje
imaju funkciju stimulacije produkcije i opsonizacije antitela, još je jedan od načina
pripreme vakcine. Vakcina pripremljena od ekstracelularne komponente S. aureus
SA2H (slime associated antigen complex SAAC) pokazala je zadovoljavajuće rezultate.
Noviji pristupi pripremi vakcine ukazuju da se kao antigen može koristiti clamping
faktor A (ClfA) Staphylococcus aureusa, kao i deo membrane površinskog proteina koji
se zove rTRAP (rekombinantni Target RNAIII Activating Protein) koji je sastavni deo
proteina 167 AA patogenih sojeva stafilokoka. Imunoprofilaksa omogućava moderan
pristup u rešavanju mastitisa izazvanih sa S. aureus, smanjenu upotrebu antibiotika u
terapiji, a samim tim i smanjeno odbacivanje mleka zbog rezidua antibiotika.
AB  - Inflammation of the udder and mastitis in cows is an acute or chronical inflammation
duct, parenchymal or interstitial one or more udder quarters. Mastitis is defined as the
response of the mammary gland in the presence of microorganisms. Mastitis represent
a major health and economic problem in herds of high yielding dairy cows but may
occur in clinical form (clinical mastitis) the prevalence of 1-3% and in the subclinical
form (sub-clinical mastitis) and the prevalence of more than 30%. Staphylococcus
aureus causes severe acute mastitis often with a change in general condition, as well
as subclinical mastitis. Treatment of mastitis does not always produce satisfactory
results, but vaccination is one of the possible approaches to solving this problem.
Staphylococci are very poor antigens, which further prevents and hinders the present
invention effective vaccines. In the literature are described different approaches to
the preparation of a vaccine against mastitis caused by S. aureus. The vaccine may
also comprise inactivated S. aureus, beta and alpha toxoid, protein A and fibronectinbinding
protein as a possible antigen in the activation of the active immune response.
Immunization of the mammary gland which is used as an antigen is incorporated in the
lysate of S. aureus biodegradable microspheres which is beneficial for production and
stimulation of opsonization of an antibody is one of the ways of preparing vaccines.
The vaccine was prepared from the extracellular components of S. aureus SA2H (slimeassociated
antigen complex SAAC) showed satisfactory results. Recent approaches in
the preparation of vaccines indicate that the antigen can be used as a clamping factor
A (ClfA) of Staphylococcus aureus, as well as part of the membrane protein called
rTRAP (recombinant Target RNAIII Activating Protein) which is a constituent part
167 AA protein of pathogenic strains of staphylococci. Immunoprophylaxis to modern
approach to the solution of mastitis caused by S. aureus, reduced use antibiotics in
therapy, and reduced rejection milk because of the antibiotic residues.
PB  - Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“
T2  - Veterinarski žurnal Republike Srpske
T1  - Značaj vakcinacije u prevenciji stafilokoknih mastitisa krava
T1  - Importance of vaccination in prevention staphylococcal mastitis
VL  - 17
IS  - 2
SP  - 170
EP  - 181
DO  - 10.7251/VETJ1702170V
ER  - 

@article{
author = "Vakanjac, Slobodanka and Maletić, Milan and Pavlović, Miloš and Obrenović, Sonja and Bojkovski, Jovan and Magaš, Vladimir",
year = "2017",
abstract = "Zapaljenje vimena ili mastitis kod krava je akutno ili hronično zapaljenje izvodnih
kanala, parenhima ili intersticijuma jedne ili više četvrti vimena krava. Mastitis
se definiše kao odgovor mlečne žlezde na prisustvo mikroorganizama. Mastitisi
predstavljaju veliki zdravstveni i ekonomski problem u zapatima visokomlečnih
krava, a mogu se javiti u kliničkoj formi (klinički mastitis) sa raširenošću 1–3% i u
subkliničkoj formi (subklinički mastitis) sa raširenošću više od 30%. Staphylococcus
aureus izaziva teške akutne mastitise veoma često sa promenom opšteg stanja, ali i
subkliničke forme mastitisa. Terapija ovog mastitisa ne daje uvek zadovoljavajuće
rezultate, pa je vakcinacija jedan od mogućih pristupa u rešavanju ovog problema.
Stafilokoke su veoma slabi antigeni, što dodatno onemogućava i otežava pronalazak
efikasne vakcine. U literaturi su opisani različiti pristupi pripreme vakcine protiv
mastitisa izazvanog S. aureusom. Vakcina može da sadrži inaktivisane bakterije
S. aureus, alfa i beta toksoide, proteina A i fibronectin-binding protein kao moguće
antigene u aktivaciji aktivnog imunološkog odgovora. Imunizovanje mlečne žlezde
gde se kao antigen koristi inkorporisan lizat S. aureus u biodegradabilne parikule koje
imaju funkciju stimulacije produkcije i opsonizacije antitela, još je jedan od načina
pripreme vakcine. Vakcina pripremljena od ekstracelularne komponente S. aureus
SA2H (slime associated antigen complex SAAC) pokazala je zadovoljavajuće rezultate.
Noviji pristupi pripremi vakcine ukazuju da se kao antigen može koristiti clamping
faktor A (ClfA) Staphylococcus aureusa, kao i deo membrane površinskog proteina koji
se zove rTRAP (rekombinantni Target RNAIII Activating Protein) koji je sastavni deo
proteina 167 AA patogenih sojeva stafilokoka. Imunoprofilaksa omogućava moderan
pristup u rešavanju mastitisa izazvanih sa S. aureus, smanjenu upotrebu antibiotika u
terapiji, a samim tim i smanjeno odbacivanje mleka zbog rezidua antibiotika., Inflammation of the udder and mastitis in cows is an acute or chronical inflammation
duct, parenchymal or interstitial one or more udder quarters. Mastitis is defined as the
response of the mammary gland in the presence of microorganisms. Mastitis represent
a major health and economic problem in herds of high yielding dairy cows but may
occur in clinical form (clinical mastitis) the prevalence of 1-3% and in the subclinical
form (sub-clinical mastitis) and the prevalence of more than 30%. Staphylococcus
aureus causes severe acute mastitis often with a change in general condition, as well
as subclinical mastitis. Treatment of mastitis does not always produce satisfactory
results, but vaccination is one of the possible approaches to solving this problem.
Staphylococci are very poor antigens, which further prevents and hinders the present
invention effective vaccines. In the literature are described different approaches to
the preparation of a vaccine against mastitis caused by S. aureus. The vaccine may
also comprise inactivated S. aureus, beta and alpha toxoid, protein A and fibronectinbinding
protein as a possible antigen in the activation of the active immune response.
Immunization of the mammary gland which is used as an antigen is incorporated in the
lysate of S. aureus biodegradable microspheres which is beneficial for production and
stimulation of opsonization of an antibody is one of the ways of preparing vaccines.
The vaccine was prepared from the extracellular components of S. aureus SA2H (slimeassociated
antigen complex SAAC) showed satisfactory results. Recent approaches in
the preparation of vaccines indicate that the antigen can be used as a clamping factor
A (ClfA) of Staphylococcus aureus, as well as part of the membrane protein called
rTRAP (recombinant Target RNAIII Activating Protein) which is a constituent part
167 AA protein of pathogenic strains of staphylococci. Immunoprophylaxis to modern
approach to the solution of mastitis caused by S. aureus, reduced use antibiotics in
therapy, and reduced rejection milk because of the antibiotic residues.",
publisher = "Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“",
journal = "Veterinarski žurnal Republike Srpske",
title = "Značaj vakcinacije u prevenciji stafilokoknih mastitisa krava, Importance of vaccination in prevention staphylococcal mastitis",
volume = "17",
number = "2",
pages = "170-181",
doi = "10.7251/VETJ1702170V"
}

Vakanjac, S., Maletić, M., Pavlović, M., Obrenović, S., Bojkovski, J.,& Magaš, V.. (2017). Značaj vakcinacije u prevenciji stafilokoknih mastitisa krava. in Veterinarski žurnal Republike Srpske
Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“., 17(2), 170-181.
https://doi.org/10.7251/VETJ1702170V

Vakanjac S, Maletić M, Pavlović M, Obrenović S, Bojkovski J, Magaš V. Značaj vakcinacije u prevenciji stafilokoknih mastitisa krava. in Veterinarski žurnal Republike Srpske. 2017;17(2):170-181.
doi:10.7251/VETJ1702170V .

Vakanjac, Slobodanka, Maletić, Milan, Pavlović, Miloš, Obrenović, Sonja, Bojkovski, Jovan, Magaš, Vladimir, "Značaj vakcinacije u prevenciji stafilokoknih mastitisa krava" in Veterinarski žurnal Republike Srpske, 17, no. 2 (2017):170-181,
https://doi.org/10.7251/VETJ1702170V . .

TY  - JOUR
AU  - Kovacić, Marijana
AU  - Marković, Dragana
AU  - Maslovarić, Irina
AU  - Obrenović, Sonja
AU  - Grujic-Milanović, Jelica
AU  - Arsić, Aleksandra
AU  - Milanović, Zorana
AU  - Savić, Olivera
AU  - Fratrić, Natalija
AU  - Ilić, Vesna
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1478
AB  - Calf bronchopneumonia is complex multifactorial disease and for its accurate diagnosis and therapy, besides clinical examination, microbiologic, hematologic and biochemical analyses could be necessary. In general, additional analyses are not implemented, mainly because the disease biomarkers are not defined. To establish which analysis might be useful for determining the severity of the disease, we analyzed 23 three-month old calves with mild clinical signs of bronchopneumonia and 15 age-matched healthy calves. Pasteurella multocida was isolated from deep nasal swabs of diseased calves. Peripheral blood erythrocyte and leukocyte count of bronchopneumonic and healthy calves showed no difference. Serum proteins, lipoproteins and lipids were analyzed with spectrophotometry, agarose gel electrophoresis, non-reducing SDSPAGE, gel zymography, and thin-layer chromatography. The bronchopneumonic calves had an increased level of circulating immune complexes and a globulins, which contain some of the positive acute phase proteins. In diseased calves the increased concentration of total. globulins (IgG), due to an increased concentration of anionic. globulins (predominately IgG1), was detected. The increased concentration of anionic. globulins followed by increased concentration of transferrin (negative acute phase protein) and HDL cholesterol, decreased concentration of LDL-cholesterol, unchanged activity of matrix metalloproteases and leukocyte counts might reflect the obvious absence of generalized inflammation. A positive correlation was found between the acquired results and the appearance of mild clinical signs. Therefore, we believe that the parameters analyzed in the peripheral blood could be applied as reliable disease markers to distinguish between severe (inflammatory) and mild forms of calf bronchopneumonia and to predict a better outcome for these calves.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Serum proteins and lipids in mild form of calf bronchopneumonia: candidates for reliable biomarkers
VL  - 67
IS  - 2
SP  - 207
EP  - 227
DO  - 10.1515/acve-2017-0018
ER  - 

@article{
author = "Kovacić, Marijana and Marković, Dragana and Maslovarić, Irina and Obrenović, Sonja and Grujic-Milanović, Jelica and Arsić, Aleksandra and Milanović, Zorana and Savić, Olivera and Fratrić, Natalija and Ilić, Vesna",
year = "2017",
abstract = "Calf bronchopneumonia is complex multifactorial disease and for its accurate diagnosis and therapy, besides clinical examination, microbiologic, hematologic and biochemical analyses could be necessary. In general, additional analyses are not implemented, mainly because the disease biomarkers are not defined. To establish which analysis might be useful for determining the severity of the disease, we analyzed 23 three-month old calves with mild clinical signs of bronchopneumonia and 15 age-matched healthy calves. Pasteurella multocida was isolated from deep nasal swabs of diseased calves. Peripheral blood erythrocyte and leukocyte count of bronchopneumonic and healthy calves showed no difference. Serum proteins, lipoproteins and lipids were analyzed with spectrophotometry, agarose gel electrophoresis, non-reducing SDSPAGE, gel zymography, and thin-layer chromatography. The bronchopneumonic calves had an increased level of circulating immune complexes and a globulins, which contain some of the positive acute phase proteins. In diseased calves the increased concentration of total. globulins (IgG), due to an increased concentration of anionic. globulins (predominately IgG1), was detected. The increased concentration of anionic. globulins followed by increased concentration of transferrin (negative acute phase protein) and HDL cholesterol, decreased concentration of LDL-cholesterol, unchanged activity of matrix metalloproteases and leukocyte counts might reflect the obvious absence of generalized inflammation. A positive correlation was found between the acquired results and the appearance of mild clinical signs. Therefore, we believe that the parameters analyzed in the peripheral blood could be applied as reliable disease markers to distinguish between severe (inflammatory) and mild forms of calf bronchopneumonia and to predict a better outcome for these calves.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Serum proteins and lipids in mild form of calf bronchopneumonia: candidates for reliable biomarkers",
volume = "67",
number = "2",
pages = "207-227",
doi = "10.1515/acve-2017-0018"
}

Kovacić, M., Marković, D., Maslovarić, I., Obrenović, S., Grujic-Milanović, J., Arsić, A., Milanović, Z., Savić, O., Fratrić, N.,& Ilić, V.. (2017). Serum proteins and lipids in mild form of calf bronchopneumonia: candidates for reliable biomarkers. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 67(2), 207-227.
https://doi.org/10.1515/acve-2017-0018

Kovacić M, Marković D, Maslovarić I, Obrenović S, Grujic-Milanović J, Arsić A, Milanović Z, Savić O, Fratrić N, Ilić V. Serum proteins and lipids in mild form of calf bronchopneumonia: candidates for reliable biomarkers. in Acta Veterinaria-Beograd. 2017;67(2):207-227.
doi:10.1515/acve-2017-0018 .

Kovacić, Marijana, Marković, Dragana, Maslovarić, Irina, Obrenović, Sonja, Grujic-Milanović, Jelica, Arsić, Aleksandra, Milanović, Zorana, Savić, Olivera, Fratrić, Natalija, Ilić, Vesna, "Serum proteins and lipids in mild form of calf bronchopneumonia: candidates for reliable biomarkers" in Acta Veterinaria-Beograd, 67, no. 2 (2017):207-227,
https://doi.org/10.1515/acve-2017-0018 . .

TY  - JOUR
AU  - Ilić, Tamara
AU  - Mandić, Maja
AU  - Stepanović, Predrag
AU  - Obrenović, Sonja
AU  - Dimitrijević, Sanda
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1443
AB  - Background. In the last fifteen years on the European continent and also worldwide, the prevalence of cardiopulmonary metastrongyloidosis in dogs and cats has increased significantly, especially cases involving those parasites which are the most important for veterinary practice (Angiostrongylus vasorum, Aelurostrongylus abstrusus and Crenosoma vulpis). Scope and Approach. The aim of this study is to present a detailed clinical-parasitological approach to highlight the importance of these helminths, and to display the newest findings concerning the diagnostic possibilities in dogs and cats Key Findings and Conclusions. The effects of global warming, vector range shift, the frequent transportation and movement of animals to other epizootic areas, as well as the intensification of merchandise transportation and movement of people are just some of the potential factors which could impact the dynamics of incidence, upkeep and spread of cardiopulmonary nematodoses in carnivores. For the timely implementation of effective treatment of sick animals, it essential to accurately diagnose these parasitoses. Accurate, timely diagnosis can, in the end, significantly contribute to the prognostic course of disease in infected carnivores. Cardiopulmonary metastrongyloidoses in dogs and cats have great clinical-parasitological significance because of their high degree of pathogenicity, their spread outside endemic areas, the difficulties encountered in establishing their diagnosis, and the fact that they represent a potential danger to human health.
AB  - Uvod. U poslednjih petnaest godina, na evropskom kontinentu i širom sveta značajno se povećala prevalencija kardiopulmonalnih metastrongilidoza kod pasa i mačaka, naročito onih uzročnika koji imaju najveći značaj za veterinarsku praksu (Angiostrongylus vasorum, Aelurostrongylus abstrusus i Crenosoma vulpis). Cilj i pristup. Cilj ovog rada je da se detaljnim kliničko-parazitološkim osvrtom istakne značaj ove grupe helmintoza i da se prikažu najnovija saznanja vezana za mogućnosti njihove dijagnostike kod pasa i mačaka. Ključni nalazi i zaključak. Efekti globalnog zagrevanja, pomeranje granica habitacije vektora, učestalo kretanje i transport životinja u druga epizootiološka područja, intenziviran promet robe i velika fluktuacija ljudi, samo su neki od potencijalnih faktora koji bi mogli uticati na ovakvu dinamiku pojavljivanja, održavanja i širenja kardiopulmonalnih nematodoza kod mesojeda. Za blagovremeno sprovođenje efikasnog tretmana obolelih jedinki neophodna je precizna dijagnostika ovih parazitoza, što u krajnjem ishodu značajno može uticati na prognostički tok oboljenja kod inficiranih mesojeda. S obzirom na stepen njihove patogenosti, poteškoće koje se javljaju u postavljanju dijagnoze, kao i činjenicu da neke od njih predstavljaju potencijalnu opasnost po zdravlje ljudi, navedena oboljenja imaju izuzetan klinički i epizootiološki značaj.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Cardiopulmonary metastrongyloidosis of dogs and cats contribution to diagnose
T1  - Kardiopulmonarna metastrongiliodoza pasa i mačaka doprinos za postavljanje dijagnoze
VL  - 71
IS  - 2
SP  - 69
EP  - 86
DO  - 10.2298/VETGL170310010I
ER  - 

@article{
author = "Ilić, Tamara and Mandić, Maja and Stepanović, Predrag and Obrenović, Sonja and Dimitrijević, Sanda",
year = "2017",
abstract = "Background. In the last fifteen years on the European continent and also worldwide, the prevalence of cardiopulmonary metastrongyloidosis in dogs and cats has increased significantly, especially cases involving those parasites which are the most important for veterinary practice (Angiostrongylus vasorum, Aelurostrongylus abstrusus and Crenosoma vulpis). Scope and Approach. The aim of this study is to present a detailed clinical-parasitological approach to highlight the importance of these helminths, and to display the newest findings concerning the diagnostic possibilities in dogs and cats Key Findings and Conclusions. The effects of global warming, vector range shift, the frequent transportation and movement of animals to other epizootic areas, as well as the intensification of merchandise transportation and movement of people are just some of the potential factors which could impact the dynamics of incidence, upkeep and spread of cardiopulmonary nematodoses in carnivores. For the timely implementation of effective treatment of sick animals, it essential to accurately diagnose these parasitoses. Accurate, timely diagnosis can, in the end, significantly contribute to the prognostic course of disease in infected carnivores. Cardiopulmonary metastrongyloidoses in dogs and cats have great clinical-parasitological significance because of their high degree of pathogenicity, their spread outside endemic areas, the difficulties encountered in establishing their diagnosis, and the fact that they represent a potential danger to human health., Uvod. U poslednjih petnaest godina, na evropskom kontinentu i širom sveta značajno se povećala prevalencija kardiopulmonalnih metastrongilidoza kod pasa i mačaka, naročito onih uzročnika koji imaju najveći značaj za veterinarsku praksu (Angiostrongylus vasorum, Aelurostrongylus abstrusus i Crenosoma vulpis). Cilj i pristup. Cilj ovog rada je da se detaljnim kliničko-parazitološkim osvrtom istakne značaj ove grupe helmintoza i da se prikažu najnovija saznanja vezana za mogućnosti njihove dijagnostike kod pasa i mačaka. Ključni nalazi i zaključak. Efekti globalnog zagrevanja, pomeranje granica habitacije vektora, učestalo kretanje i transport životinja u druga epizootiološka područja, intenziviran promet robe i velika fluktuacija ljudi, samo su neki od potencijalnih faktora koji bi mogli uticati na ovakvu dinamiku pojavljivanja, održavanja i širenja kardiopulmonalnih nematodoza kod mesojeda. Za blagovremeno sprovođenje efikasnog tretmana obolelih jedinki neophodna je precizna dijagnostika ovih parazitoza, što u krajnjem ishodu značajno može uticati na prognostički tok oboljenja kod inficiranih mesojeda. S obzirom na stepen njihove patogenosti, poteškoće koje se javljaju u postavljanju dijagnoze, kao i činjenicu da neke od njih predstavljaju potencijalnu opasnost po zdravlje ljudi, navedena oboljenja imaju izuzetan klinički i epizootiološki značaj.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Cardiopulmonary metastrongyloidosis of dogs and cats contribution to diagnose, Kardiopulmonarna metastrongiliodoza pasa i mačaka doprinos za postavljanje dijagnoze",
volume = "71",
number = "2",
pages = "69-86",
doi = "10.2298/VETGL170310010I"
}

Ilić, T., Mandić, M., Stepanović, P., Obrenović, S.,& Dimitrijević, S.. (2017). Cardiopulmonary metastrongyloidosis of dogs and cats contribution to diagnose. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 71(2), 69-86.
https://doi.org/10.2298/VETGL170310010I

Ilić T, Mandić M, Stepanović P, Obrenović S, Dimitrijević S. Cardiopulmonary metastrongyloidosis of dogs and cats contribution to diagnose. in Veterinarski Glasnik. 2017;71(2):69-86.
doi:10.2298/VETGL170310010I .

Ilić, Tamara, Mandić, Maja, Stepanović, Predrag, Obrenović, Sonja, Dimitrijević, Sanda, "Cardiopulmonary metastrongyloidosis of dogs and cats contribution to diagnose" in Veterinarski Glasnik, 71, no. 2 (2017):69-86,
https://doi.org/10.2298/VETGL170310010I . .

TY  - JOUR
AU  - Obrenović, Sonja
AU  - Ristanović, Elizabeta
AU  - Cekanac, Radovan
AU  - Radulović, Željko
AU  - Ilić, Vesna
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1179
AB  - In this study the seroprevalence of anti-Borrelia burgdorferi IgG antibodies in populations of naturally exposed dogs in the Belgrade area was determined. Serum samples of 215 dogs were tested with in-house made indirect immunofluorescent-antibody assay (IFA), enzyme-linked immunosorbent assay (ELISA), and Western blot assay (WB). Sera were from 34 pet dogs suspected of having Lyme borreliosis, 41 hunting dogs, 125 shelter dogs, and 15 clinically healthy pet dogs. Results of WB were used as a standard against which the performances of ELISA and IFA were evaluated. ELISA was significantly more sensitive than IFA (84.8 vs 67.9%), whereas the specificities of these tests were just slightly different (94.4% vs 92.6 %). Borrelia burgdorferi seroprevalence of 24.7% among tested dogs was recorded by WB test. The highest seroprevalence of 31.2% was found in the group of shelter dogs, while hunting and pet dogs showed lower seroprevalence of 19.5% and 17.6%, but the difference was statistically insignificant. These results are the first report on the seroprevalence of IgG antibodies to B. burgdorferi in dogs in the Belgrade area and could be of importance in the assessment of the risk of infection with B. burgdorferi in human population.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Seroprevalence of igg antibodies against borrelia burgdorferi in dogs in Belgrade area, Serbia
VL  - 65
IS  - 1
SP  - 99
EP  - 110
DO  - 10.1515/acve-2015-0008
ER  - 

@article{
author = "Obrenović, Sonja and Ristanović, Elizabeta and Cekanac, Radovan and Radulović, Željko and Ilić, Vesna",
year = "2015",
abstract = "In this study the seroprevalence of anti-Borrelia burgdorferi IgG antibodies in populations of naturally exposed dogs in the Belgrade area was determined. Serum samples of 215 dogs were tested with in-house made indirect immunofluorescent-antibody assay (IFA), enzyme-linked immunosorbent assay (ELISA), and Western blot assay (WB). Sera were from 34 pet dogs suspected of having Lyme borreliosis, 41 hunting dogs, 125 shelter dogs, and 15 clinically healthy pet dogs. Results of WB were used as a standard against which the performances of ELISA and IFA were evaluated. ELISA was significantly more sensitive than IFA (84.8 vs 67.9%), whereas the specificities of these tests were just slightly different (94.4% vs 92.6 %). Borrelia burgdorferi seroprevalence of 24.7% among tested dogs was recorded by WB test. The highest seroprevalence of 31.2% was found in the group of shelter dogs, while hunting and pet dogs showed lower seroprevalence of 19.5% and 17.6%, but the difference was statistically insignificant. These results are the first report on the seroprevalence of IgG antibodies to B. burgdorferi in dogs in the Belgrade area and could be of importance in the assessment of the risk of infection with B. burgdorferi in human population.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Seroprevalence of igg antibodies against borrelia burgdorferi in dogs in Belgrade area, Serbia",
volume = "65",
number = "1",
pages = "99-110",
doi = "10.1515/acve-2015-0008"
}

Obrenović, S., Ristanović, E., Cekanac, R., Radulović, Ž.,& Ilić, V.. (2015). Seroprevalence of igg antibodies against borrelia burgdorferi in dogs in Belgrade area, Serbia. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 65(1), 99-110.
https://doi.org/10.1515/acve-2015-0008

Obrenović S, Ristanović E, Cekanac R, Radulović Ž, Ilić V. Seroprevalence of igg antibodies against borrelia burgdorferi in dogs in Belgrade area, Serbia. in Acta Veterinaria-Beograd. 2015;65(1):99-110.
doi:10.1515/acve-2015-0008 .

Obrenović, Sonja, Ristanović, Elizabeta, Cekanac, Radovan, Radulović, Željko, Ilić, Vesna, "Seroprevalence of igg antibodies against borrelia burgdorferi in dogs in Belgrade area, Serbia" in Acta Veterinaria-Beograd, 65, no. 1 (2015):99-110,
https://doi.org/10.1515/acve-2015-0008 . .

TY  - JOUR
AU  - Obrenović, Sonja
AU  - Radojičić, Sonja
AU  - Stević, Nataša
AU  - Bogunović, Danica
AU  - Vakanjac, Slobodanka
AU  - Valčić, Miroslav
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1160
AB  - With its epizootiological characteristics, the territory of the municipality of Belgrade city is a potentially important locality for the maintenance and spreading of a number of serovars of Leptospira interrogans. In order to evaluate the epizootiological situation as far as animal leptospirosis in the Belgrade region is concerned, from January 2012 until June 2013 the prevalence of cat leptospirosis has been evaluated. The standard microagglutination test (MAT) was used to determine animals sero positive to different serovars that belong to L. interrogans sensu lato complex. The antigens used were: Icterohaemorrhagiae, Grippotyphosa, Pomona, Canicola, Bratislava, Batavie, Sejroe, Pyrogenes, Australis and Autumnalis. Out of the total number of tested animals, there were 43 (26.7%) positive to one, two or three serovar(s). Out of a total of 43 positive sera 20 (46.5%) samples were positive to more than one leptospira serovar.
AB  - Svojim epizootiološkim karakteristikama, teritorija grada Beograda je potencijalno značajna lokacija za održavanje i širenje brojnih serovarijeteta vrste Leptospira interrogans. U cilju evaluacije epizootiološke situacije u odnosu na leptospirozu kod vrsta životinja na teritoriji grada Beograda, obavljena su ispitivanja seroprevalencije leptospiroze mačaka u periodu od januara 2012. godine, do juna 2013. godine. Radi utvrđivanja prisustva antitela na različite serovarijetete leptospira, kao dijagnostički metod, upotrebljen je standardni mikroaglutinacioni test (MAT). U okviru navedene dijagnostičke metode, upotrebljeni su različiti serovarijeteti bakterije L. interrogans sensu lato kompleksa i to: sv. Icterohaemorrhagiae, sv. Grippotyphosa, sv. Pomona, sv. Canicola, sv. Bratislava, sv. Batavie, sv. Sejroe, sv. Pyrogenes, sv. Australis i sv. Autumnalis. Od ukupnog broja ispitivanih životinja, pozitivnih je bilo 43 (26.7%) i to jedan, dva i/ili tri serovarijeteta. Od ukupnog broja seropozitivnih životinja, 20 seruma (46.5%) je bilo seropozitivno na više od jedan serovarijetet leptospira.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Seroprevalence of cat leptospirosis in Belgrade: Serbia
T1  - Seroprevalencija leptospiroze mačaka na teritoriji Beograda - Srbija
VL  - 64
IS  - 4
SP  - 510
EP  - 518
DO  - 10.2478/acve-2014-0047
ER  - 

@article{
author = "Obrenović, Sonja and Radojičić, Sonja and Stević, Nataša and Bogunović, Danica and Vakanjac, Slobodanka and Valčić, Miroslav",
year = "2014",
abstract = "With its epizootiological characteristics, the territory of the municipality of Belgrade city is a potentially important locality for the maintenance and spreading of a number of serovars of Leptospira interrogans. In order to evaluate the epizootiological situation as far as animal leptospirosis in the Belgrade region is concerned, from January 2012 until June 2013 the prevalence of cat leptospirosis has been evaluated. The standard microagglutination test (MAT) was used to determine animals sero positive to different serovars that belong to L. interrogans sensu lato complex. The antigens used were: Icterohaemorrhagiae, Grippotyphosa, Pomona, Canicola, Bratislava, Batavie, Sejroe, Pyrogenes, Australis and Autumnalis. Out of the total number of tested animals, there were 43 (26.7%) positive to one, two or three serovar(s). Out of a total of 43 positive sera 20 (46.5%) samples were positive to more than one leptospira serovar., Svojim epizootiološkim karakteristikama, teritorija grada Beograda je potencijalno značajna lokacija za održavanje i širenje brojnih serovarijeteta vrste Leptospira interrogans. U cilju evaluacije epizootiološke situacije u odnosu na leptospirozu kod vrsta životinja na teritoriji grada Beograda, obavljena su ispitivanja seroprevalencije leptospiroze mačaka u periodu od januara 2012. godine, do juna 2013. godine. Radi utvrđivanja prisustva antitela na različite serovarijetete leptospira, kao dijagnostički metod, upotrebljen je standardni mikroaglutinacioni test (MAT). U okviru navedene dijagnostičke metode, upotrebljeni su različiti serovarijeteti bakterije L. interrogans sensu lato kompleksa i to: sv. Icterohaemorrhagiae, sv. Grippotyphosa, sv. Pomona, sv. Canicola, sv. Bratislava, sv. Batavie, sv. Sejroe, sv. Pyrogenes, sv. Australis i sv. Autumnalis. Od ukupnog broja ispitivanih životinja, pozitivnih je bilo 43 (26.7%) i to jedan, dva i/ili tri serovarijeteta. Od ukupnog broja seropozitivnih životinja, 20 seruma (46.5%) je bilo seropozitivno na više od jedan serovarijetet leptospira.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Seroprevalence of cat leptospirosis in Belgrade: Serbia, Seroprevalencija leptospiroze mačaka na teritoriji Beograda - Srbija",
volume = "64",
number = "4",
pages = "510-518",
doi = "10.2478/acve-2014-0047"
}

Obrenović, S., Radojičić, S., Stević, N., Bogunović, D., Vakanjac, S.,& Valčić, M.. (2014). Seroprevalence of cat leptospirosis in Belgrade: Serbia. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 64(4), 510-518.
https://doi.org/10.2478/acve-2014-0047

Obrenović S, Radojičić S, Stević N, Bogunović D, Vakanjac S, Valčić M. Seroprevalence of cat leptospirosis in Belgrade: Serbia. in Acta Veterinaria-Beograd. 2014;64(4):510-518.
doi:10.2478/acve-2014-0047 .

Obrenović, Sonja, Radojičić, Sonja, Stević, Nataša, Bogunović, Danica, Vakanjac, Slobodanka, Valčić, Miroslav, "Seroprevalence of cat leptospirosis in Belgrade: Serbia" in Acta Veterinaria-Beograd, 64, no. 4 (2014):510-518,
https://doi.org/10.2478/acve-2014-0047 . .

TY  - JOUR
AU  - Valčić, Miroslav
AU  - Radojičić, Sonja
AU  - Žugić, Gordana
AU  - Knežević, D.
AU  - Bjelica, Jelena
AU  - Obrenović, Sonja
AU  - Nedić, Drago
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2112
AB  - Značajan segment profesionalnog angažovanja doktora veterinarske medicine
predstavlja tzv. mala praksa; često nazvana i luksuzna, s obzirom na, većim delom,
sentimentalnu vrednost pacijenata. Najčešće se radi o psima i mačkama koji u
veterinarsku ambulantu (kliniku) dolaze i povodom sprovođenja imunoprofilaktičkih mera, tj. vakcinacija, kojima se sprečavaju odnosno kontrolišu najznačajnije infektivne
bolesti ove dve vrste životinja. Ne razmatrajući osnovne preduslove za sticanje
adekvatne zaštite odnosno pravilne reakcije na vakcinu, u radu se ukazuje na nove
sisteme imunoprofilakse i upotrebu novih imunogena. Naime, za vakcinaciju pasa na
tržištu se nalaze u različitim formulacijama kako inaktivisani tako i atenuisani imunogeni
parvovirusa pasa, atenuisani adenovirusi i paramiksovirusi (štenećak i parainfluenca).
U slučaju vakcinacije mačaka, kontrolišu se kalici, herpes, parvovirusne i retrovirusne
infekcije, kao i hlamidioza mačaka. Neka infektivna oboljenja pasa i mačaka su zoonoze.
Tako se, na primer, infekcije sa leptospirama kontrolišu inaktivisanim vakcinama koje
tradicionalno sadrže serotipove koji su od značaja kako za pse tako i za ljude (serotipovi
Canicola i Icterohaemorrhagiae). Od značaja je svakako i činjenica da se u populacijama
pasa i mačaka pojavljuju i neki drugi serotipovi bakterije L. interrogans. Dobro je poznata
epizootiološka činjenica da se psi pojavljuju kao rezervoari gore napomenutih serotipova
ali, po svemu sudeći, i mačke igraju značajnu ulogu u održavanju leptospiroze u našem regionu. Postojanje maternalnog imuniteta nije i jedini problem prilikom vakcinacije
mladih životinja. Naime, u nekim slučajevima, uspešno sproveden protokol vakcinacije,
na primer, protiv parvovirusne infekcije pasa, obezbeđuje višegodišnju zaštitu pa je u
takvim slučajevima vakcinacija jednom godišnje kontraindikovana.
AB  - A significant segment of professional engagement for doctor of veterinary medicine is the
so called. small practice; often referred as luxury, given the largely sentimental value to
patients. Frequently, it comes to dogs and cats that in veterinary clinic (clinic) come because
of the occasion for the implementation of immunoprophylactic measures ie. vaccinations
that prevent or control the most important infectious diseases of these two species. Not
considering the basic prerequisites for obtaining of adequate protection or proper reaction
to the vaccine, the paper points to the new systems of immunoprophylaxis and use of new
immunogens. Namely, for the dogs vaccination, in market are in various formulations
inactivated and attenuated immunogenic parvovirus, adeno and attenuated paramyxovirus
(distemper and parainfluenza) viruses. In the case of vaccination of cats, calici, herpes,
parvo and retro viral infections and chlamydiosis of cats controlled. Some infectious diseases
of dogs and cats are zoonoses. For example, infection with leptospires, control is
with inactivated vaccines traditionally serotypes that are of importance for both dogs and
humans (serotypes canicola and icterohaemorrhagiae). Of importance is certainly the fact
that in populations of dogs and cats appear and some other serotypes of L. interrogans.
Well known is epidemiological fact that dogs appear as reservoirs of the serotypes, but
apparently cats play an important role in the maintenance of leptospirosis in our region.
The existence of maternal immunity is not the only problem during the vaccination of
young animals. Namely, in some cases successfully executed the protocol of vaccination,
for example against parvoviral infections of dogs, provides long-term protection and is in
such cases, vaccination once per year, is contraindicated.
PB  - Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“
T2  - Veterinarski žurnal Republike Srpske
T1  - Najvažnije bolesti pasa i mačaka i novi trendovi u imunoprofilaksi
T1  - The most important diseases in dogs and cats and new trends in immunoprophylaxis
VL  - 14
IS  - 2
SP  - 163
EP  - 180
DO  - 10.7251/VETJ1402163V
ER  - 

@article{
author = "Valčić, Miroslav and Radojičić, Sonja and Žugić, Gordana and Knežević, D. and Bjelica, Jelena and Obrenović, Sonja and Nedić, Drago",
year = "2014",
abstract = "Značajan segment profesionalnog angažovanja doktora veterinarske medicine
predstavlja tzv. mala praksa; često nazvana i luksuzna, s obzirom na, većim delom,
sentimentalnu vrednost pacijenata. Najčešće se radi o psima i mačkama koji u
veterinarsku ambulantu (kliniku) dolaze i povodom sprovođenja imunoprofilaktičkih mera, tj. vakcinacija, kojima se sprečavaju odnosno kontrolišu najznačajnije infektivne
bolesti ove dve vrste životinja. Ne razmatrajući osnovne preduslove za sticanje
adekvatne zaštite odnosno pravilne reakcije na vakcinu, u radu se ukazuje na nove
sisteme imunoprofilakse i upotrebu novih imunogena. Naime, za vakcinaciju pasa na
tržištu se nalaze u različitim formulacijama kako inaktivisani tako i atenuisani imunogeni
parvovirusa pasa, atenuisani adenovirusi i paramiksovirusi (štenećak i parainfluenca).
U slučaju vakcinacije mačaka, kontrolišu se kalici, herpes, parvovirusne i retrovirusne
infekcije, kao i hlamidioza mačaka. Neka infektivna oboljenja pasa i mačaka su zoonoze.
Tako se, na primer, infekcije sa leptospirama kontrolišu inaktivisanim vakcinama koje
tradicionalno sadrže serotipove koji su od značaja kako za pse tako i za ljude (serotipovi
Canicola i Icterohaemorrhagiae). Od značaja je svakako i činjenica da se u populacijama
pasa i mačaka pojavljuju i neki drugi serotipovi bakterije L. interrogans. Dobro je poznata
epizootiološka činjenica da se psi pojavljuju kao rezervoari gore napomenutih serotipova
ali, po svemu sudeći, i mačke igraju značajnu ulogu u održavanju leptospiroze u našem regionu. Postojanje maternalnog imuniteta nije i jedini problem prilikom vakcinacije
mladih životinja. Naime, u nekim slučajevima, uspešno sproveden protokol vakcinacije,
na primer, protiv parvovirusne infekcije pasa, obezbeđuje višegodišnju zaštitu pa je u
takvim slučajevima vakcinacija jednom godišnje kontraindikovana., A significant segment of professional engagement for doctor of veterinary medicine is the
so called. small practice; often referred as luxury, given the largely sentimental value to
patients. Frequently, it comes to dogs and cats that in veterinary clinic (clinic) come because
of the occasion for the implementation of immunoprophylactic measures ie. vaccinations
that prevent or control the most important infectious diseases of these two species. Not
considering the basic prerequisites for obtaining of adequate protection or proper reaction
to the vaccine, the paper points to the new systems of immunoprophylaxis and use of new
immunogens. Namely, for the dogs vaccination, in market are in various formulations
inactivated and attenuated immunogenic parvovirus, adeno and attenuated paramyxovirus
(distemper and parainfluenza) viruses. In the case of vaccination of cats, calici, herpes,
parvo and retro viral infections and chlamydiosis of cats controlled. Some infectious diseases
of dogs and cats are zoonoses. For example, infection with leptospires, control is
with inactivated vaccines traditionally serotypes that are of importance for both dogs and
humans (serotypes canicola and icterohaemorrhagiae). Of importance is certainly the fact
that in populations of dogs and cats appear and some other serotypes of L. interrogans.
Well known is epidemiological fact that dogs appear as reservoirs of the serotypes, but
apparently cats play an important role in the maintenance of leptospirosis in our region.
The existence of maternal immunity is not the only problem during the vaccination of
young animals. Namely, in some cases successfully executed the protocol of vaccination,
for example against parvoviral infections of dogs, provides long-term protection and is in
such cases, vaccination once per year, is contraindicated.",
publisher = "Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“",
journal = "Veterinarski žurnal Republike Srpske",
title = "Najvažnije bolesti pasa i mačaka i novi trendovi u imunoprofilaksi, The most important diseases in dogs and cats and new trends in immunoprophylaxis",
volume = "14",
number = "2",
pages = "163-180",
doi = "10.7251/VETJ1402163V"
}

Valčić, M., Radojičić, S., Žugić, G., Knežević, D., Bjelica, J., Obrenović, S.,& Nedić, D.. (2014). Najvažnije bolesti pasa i mačaka i novi trendovi u imunoprofilaksi. in Veterinarski žurnal Republike Srpske
Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“., 14(2), 163-180.
https://doi.org/10.7251/VETJ1402163V

Valčić M, Radojičić S, Žugić G, Knežević D, Bjelica J, Obrenović S, Nedić D. Najvažnije bolesti pasa i mačaka i novi trendovi u imunoprofilaksi. in Veterinarski žurnal Republike Srpske. 2014;14(2):163-180.
doi:10.7251/VETJ1402163V .

Valčić, Miroslav, Radojičić, Sonja, Žugić, Gordana, Knežević, D., Bjelica, Jelena, Obrenović, Sonja, Nedić, Drago, "Najvažnije bolesti pasa i mačaka i novi trendovi u imunoprofilaksi" in Veterinarski žurnal Republike Srpske, 14, no. 2 (2014):163-180,
https://doi.org/10.7251/VETJ1402163V . .

TY  - JOUR
AU  - Potkonjak, Aleksandar
AU  - Savić, Sara
AU  - Vračar, Vuk
AU  - Rnjak, Dušan
AU  - Tikvicki, Mario
AU  - Obrenović, Sonja
AU  - Lako, Branislav
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/961
AB  - Lyme disease is a multisystemic disease, zoonotic in nature, caused by the Borrelia burgdorferi sensu lato complex. In the continent of Europe, these spirochetes are predominantly transmitted by ticks of the genus Ixodes. Small mammals and birds have particular significance as reservoirs of the cause of lyme disease. The objective of these epidemiological investigations was to determine the value of IgG seroprevalence to Borrelia burgdorferi and to secure the geographic distribution of seropositive dogs in Vojvodina. The investigations covered 135 dogs that were not vaccinated against lyme disease. The indirect ELISA test was used to determine IgG prevalence to Borrelia burgdorferi antigens. Reactive blood serums of dogs were tested again using the rapid immunochromatographic and immunoblot test. A seroprevalence of G class antibodies to antigens of lyme disease causes of 8.1% (11/135) was established in the examined dog population of Vojvodina. The biggest number of positive results was recorded for the South Bačka District. The presented value for the seroprevalence of anti-Borrelia burgdorferi antibodies in the dog population indicates the exhistence of a significant risk of humans becoming infected with the cause of lyme disease in Vojvodina.
AB  - Lajmska bolest je multisistemsko oboljenje, zoonoznog karaktera, izazvano uzročnikom Borrelia burgdorferi sensu lato complex. Ove spirohete se na evropskom kontinentu dominantno prenose krpeljima iz roda Ixodes. Poseban epidemiološki značaj imaju mali sisari i ptice kao rezervoari uzročnika lajmske bolesti. Cilj ovog epidemiološ kog istraživanja je da se utvrdi vrednost seroprevalencije IgG na Borrelia burgdorferi i sagleda geografska distribucija seropozitivnih pasa u Vojvodini. U ispitivanje je bilo uključeno 135 pasa koji nisu vakcinisani protiv lajmske bolesti. Za utvrđivanje prevalencije IgG na antigene Borrelia burgdorferi korišćen je indirektni ELISA test. Reaktivni krvni serumi pasa su ponovo testirani primenom brzog imunohromatografskog i imunoblot testa. Ustanovljena je seroprevalencija antitela klase G na antigene uzročnika lajmske bolesti od 8,1% (11/135) u populaciji pasa na području Vojvodine. Najveći broj pozitivnih rezultata je zabeležen u Južnobačkom okrugu. Navedena vrednost seroprevalencije anti-Borrelia burgdorferi antitela u populaciji pasa ukazuje na postojanje značajnog rizika za infekciju kod ljudi izazvanu uzročnikom lajmske bolesti u Vojvodini.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Prevalence of G class antibodies to antigens of lyme disease causes in dogs in Vojvodina, Serbia
T1  - Prevalencija antitela klase G na antigene uzročnika lajmske bolesti kod pasa u Vojvodini, Srbija
VL  - 67
IS  - 1-2
SP  - 55
EP  - 66
DO  - 10.2298/VETGL1302055P
ER  - 

@article{
author = "Potkonjak, Aleksandar and Savić, Sara and Vračar, Vuk and Rnjak, Dušan and Tikvicki, Mario and Obrenović, Sonja and Lako, Branislav",
year = "2013",
abstract = "Lyme disease is a multisystemic disease, zoonotic in nature, caused by the Borrelia burgdorferi sensu lato complex. In the continent of Europe, these spirochetes are predominantly transmitted by ticks of the genus Ixodes. Small mammals and birds have particular significance as reservoirs of the cause of lyme disease. The objective of these epidemiological investigations was to determine the value of IgG seroprevalence to Borrelia burgdorferi and to secure the geographic distribution of seropositive dogs in Vojvodina. The investigations covered 135 dogs that were not vaccinated against lyme disease. The indirect ELISA test was used to determine IgG prevalence to Borrelia burgdorferi antigens. Reactive blood serums of dogs were tested again using the rapid immunochromatographic and immunoblot test. A seroprevalence of G class antibodies to antigens of lyme disease causes of 8.1% (11/135) was established in the examined dog population of Vojvodina. The biggest number of positive results was recorded for the South Bačka District. The presented value for the seroprevalence of anti-Borrelia burgdorferi antibodies in the dog population indicates the exhistence of a significant risk of humans becoming infected with the cause of lyme disease in Vojvodina., Lajmska bolest je multisistemsko oboljenje, zoonoznog karaktera, izazvano uzročnikom Borrelia burgdorferi sensu lato complex. Ove spirohete se na evropskom kontinentu dominantno prenose krpeljima iz roda Ixodes. Poseban epidemiološki značaj imaju mali sisari i ptice kao rezervoari uzročnika lajmske bolesti. Cilj ovog epidemiološ kog istraživanja je da se utvrdi vrednost seroprevalencije IgG na Borrelia burgdorferi i sagleda geografska distribucija seropozitivnih pasa u Vojvodini. U ispitivanje je bilo uključeno 135 pasa koji nisu vakcinisani protiv lajmske bolesti. Za utvrđivanje prevalencije IgG na antigene Borrelia burgdorferi korišćen je indirektni ELISA test. Reaktivni krvni serumi pasa su ponovo testirani primenom brzog imunohromatografskog i imunoblot testa. Ustanovljena je seroprevalencija antitela klase G na antigene uzročnika lajmske bolesti od 8,1% (11/135) u populaciji pasa na području Vojvodine. Najveći broj pozitivnih rezultata je zabeležen u Južnobačkom okrugu. Navedena vrednost seroprevalencije anti-Borrelia burgdorferi antitela u populaciji pasa ukazuje na postojanje značajnog rizika za infekciju kod ljudi izazvanu uzročnikom lajmske bolesti u Vojvodini.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Prevalence of G class antibodies to antigens of lyme disease causes in dogs in Vojvodina, Serbia, Prevalencija antitela klase G na antigene uzročnika lajmske bolesti kod pasa u Vojvodini, Srbija",
volume = "67",
number = "1-2",
pages = "55-66",
doi = "10.2298/VETGL1302055P"
}

Potkonjak, A., Savić, S., Vračar, V., Rnjak, D., Tikvicki, M., Obrenović, S.,& Lako, B.. (2013). Prevalence of G class antibodies to antigens of lyme disease causes in dogs in Vojvodina, Serbia. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 67(1-2), 55-66.
https://doi.org/10.2298/VETGL1302055P

Potkonjak A, Savić S, Vračar V, Rnjak D, Tikvicki M, Obrenović S, Lako B. Prevalence of G class antibodies to antigens of lyme disease causes in dogs in Vojvodina, Serbia. in Veterinarski Glasnik. 2013;67(1-2):55-66.
doi:10.2298/VETGL1302055P .

Potkonjak, Aleksandar, Savić, Sara, Vračar, Vuk, Rnjak, Dušan, Tikvicki, Mario, Obrenović, Sonja, Lako, Branislav, "Prevalence of G class antibodies to antigens of lyme disease causes in dogs in Vojvodina, Serbia" in Veterinarski Glasnik, 67, no. 1-2 (2013):55-66,
https://doi.org/10.2298/VETGL1302055P . .

TY  - JOUR
AU  - Potkonjak, Aleksandar
AU  - Jurišić, Aleksandar
AU  - Petrović, Aleksandra
AU  - Nićin, Slobodan
AU  - Rajković, Dragana
AU  - Lako, Branislav
AU  - Obrenović, Sonja
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1000
AB  - In Europe, of all the vector transmitted diseases, the occurrence of lyme disease is the one most often registered, and the most significant vector Borrelia burgdorferi is the tick Ixodes ricinus. Both humans and animals contract lyme disease. The risk of the occurrence of lyme disease is in correlation with potential exposure to tick bites and depends on the density of the tick population in the endemic area, the percentage of ticks infected with the cause of lyme disease, the duration and the nature of the activity of the susceptible population in a certain area. The objective of these investigations was to determine the entomological and the ecological risk index, as well as to assess the risk of transmission of the cause of lyme disease in the territory of Vojvodina Province in the Republic of Serbia. Ticks were collected at 12 locations in the South Bačka District of Vojvodina. A total of 1400 ticks were identified up to the level of species. After establishing the infection of ticks with the cause of lyme disease, the entomological and the ecological index was determined for the given regions using microscopic examination in a dark field. Two species of ticks aere identified in this geographic region (Ixodes ricinus and Dermacentor marginatus). Examining I. ricinus, the prevalence of infection B. burgdorferi was established, ranging up to 33.1%. The ecological risk index indicates that there is a potential risk of humans and animals becoming infected at 8 localities. It was determined for 3 localities that there is a definite actual risk of the transferrence of causes of lyme disease.
AB  - U Evropi se, od svih vektorski prenosivih infekcija, najčešće registruje lajmska bolest, a najznačajniji vektor Borrelia burgdorferi je krpelj Ixodes ricinus. Od lajmske bolesti obolevaju ljudi i životinje. Rizik za pojavu lajmske bolesti je u korelaciji sa potencijalnim izlaganjem ubodu krpelja i zavisi od gustine populacije krpelja u endemskom području, procenta krpelja zaraženih uzročnikom lajmske bolesti, dužine i prirode aktivnosti prijemčive populacije na određenom području. Cilj ovog istraživanja je da se ustanove entomološki i ekološki indeks rizika, kao i da se proceni rizik transmisije uzročnika lajmske bolesti na području Vojvodine, Srbija. Prikupljanje krpelja je obavljeno na 12 lokacija Južnobačkog okruga, Srbija. Ukupno je do nivoa vrste identifikovano 1400 krpelja. Nakon utvrđivanja zaraženosti krpelja uzročnikom lajmske bolesti, primenom mikroskopskog pregleda u tamnom polju, izračunati su entomološki i ekološki indeks rizika za data područja. Identifikovane su dve vrste krpelja na našem geografskom području - Ixodes ricinus i Dermacentor marginatus. Kod I. ricinus utvrđena je prevalencija infekcije izazvane B. burgdorferi, koja se kretala do 33,1%. Ekološki indeks rizika ukazuje na to da potencijalni rizik od zaražavanja ljudi i životinja postoji na 8 lakaliteta. Za 3 lokaliteta je utvrđen definitivan aktuelni rizik za prenošenje uzročnika lajmske bolesti.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Entomological and ecological index for risk of infection causing lyme disease in territory of Vojvodina, Serbia
T1  - Entomološki i ekološki indeks rizika za pojavu lajmske bolesti na području Vojvodine, Srbija
VL  - 67
IS  - 1-2
SP  - 3
EP  - 14
DO  - 10.2298/VETGL1302003P
ER  - 

@article{
author = "Potkonjak, Aleksandar and Jurišić, Aleksandar and Petrović, Aleksandra and Nićin, Slobodan and Rajković, Dragana and Lako, Branislav and Obrenović, Sonja",
year = "2013",
abstract = "In Europe, of all the vector transmitted diseases, the occurrence of lyme disease is the one most often registered, and the most significant vector Borrelia burgdorferi is the tick Ixodes ricinus. Both humans and animals contract lyme disease. The risk of the occurrence of lyme disease is in correlation with potential exposure to tick bites and depends on the density of the tick population in the endemic area, the percentage of ticks infected with the cause of lyme disease, the duration and the nature of the activity of the susceptible population in a certain area. The objective of these investigations was to determine the entomological and the ecological risk index, as well as to assess the risk of transmission of the cause of lyme disease in the territory of Vojvodina Province in the Republic of Serbia. Ticks were collected at 12 locations in the South Bačka District of Vojvodina. A total of 1400 ticks were identified up to the level of species. After establishing the infection of ticks with the cause of lyme disease, the entomological and the ecological index was determined for the given regions using microscopic examination in a dark field. Two species of ticks aere identified in this geographic region (Ixodes ricinus and Dermacentor marginatus). Examining I. ricinus, the prevalence of infection B. burgdorferi was established, ranging up to 33.1%. The ecological risk index indicates that there is a potential risk of humans and animals becoming infected at 8 localities. It was determined for 3 localities that there is a definite actual risk of the transferrence of causes of lyme disease., U Evropi se, od svih vektorski prenosivih infekcija, najčešće registruje lajmska bolest, a najznačajniji vektor Borrelia burgdorferi je krpelj Ixodes ricinus. Od lajmske bolesti obolevaju ljudi i životinje. Rizik za pojavu lajmske bolesti je u korelaciji sa potencijalnim izlaganjem ubodu krpelja i zavisi od gustine populacije krpelja u endemskom području, procenta krpelja zaraženih uzročnikom lajmske bolesti, dužine i prirode aktivnosti prijemčive populacije na određenom području. Cilj ovog istraživanja je da se ustanove entomološki i ekološki indeks rizika, kao i da se proceni rizik transmisije uzročnika lajmske bolesti na području Vojvodine, Srbija. Prikupljanje krpelja je obavljeno na 12 lokacija Južnobačkog okruga, Srbija. Ukupno je do nivoa vrste identifikovano 1400 krpelja. Nakon utvrđivanja zaraženosti krpelja uzročnikom lajmske bolesti, primenom mikroskopskog pregleda u tamnom polju, izračunati su entomološki i ekološki indeks rizika za data područja. Identifikovane su dve vrste krpelja na našem geografskom području - Ixodes ricinus i Dermacentor marginatus. Kod I. ricinus utvrđena je prevalencija infekcije izazvane B. burgdorferi, koja se kretala do 33,1%. Ekološki indeks rizika ukazuje na to da potencijalni rizik od zaražavanja ljudi i životinja postoji na 8 lakaliteta. Za 3 lokaliteta je utvrđen definitivan aktuelni rizik za prenošenje uzročnika lajmske bolesti.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Entomological and ecological index for risk of infection causing lyme disease in territory of Vojvodina, Serbia, Entomološki i ekološki indeks rizika za pojavu lajmske bolesti na području Vojvodine, Srbija",
volume = "67",
number = "1-2",
pages = "3-14",
doi = "10.2298/VETGL1302003P"
}

Potkonjak, A., Jurišić, A., Petrović, A., Nićin, S., Rajković, D., Lako, B.,& Obrenović, S.. (2013). Entomological and ecological index for risk of infection causing lyme disease in territory of Vojvodina, Serbia. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 67(1-2), 3-14.
https://doi.org/10.2298/VETGL1302003P

Potkonjak A, Jurišić A, Petrović A, Nićin S, Rajković D, Lako B, Obrenović S. Entomological and ecological index for risk of infection causing lyme disease in territory of Vojvodina, Serbia. in Veterinarski Glasnik. 2013;67(1-2):3-14.
doi:10.2298/VETGL1302003P .

Potkonjak, Aleksandar, Jurišić, Aleksandar, Petrović, Aleksandra, Nićin, Slobodan, Rajković, Dragana, Lako, Branislav, Obrenović, Sonja, "Entomological and ecological index for risk of infection causing lyme disease in territory of Vojvodina, Serbia" in Veterinarski Glasnik, 67, no. 1-2 (2013):3-14,
https://doi.org/10.2298/VETGL1302003P . .

TY  - JOUR
AU  - Valčić, Miroslav A.
AU  - Radojičić, Sonja
AU  - Bacić, Dragan
AU  - Obrenović, Sonja
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2096
AB  - Kada se govori o rezistenciji mikroorganizama, naročito u veterinarskoj medicini, najčešće se misli na sojeve bakterija koji su otporni na hemioterapeutike, prevashodno antibiotike. Uobičajeno dodavanje antibiotika stočnoj hrani, neselektivna, nekontrolisana i često bezrazložna upotreba antibiotika u terapiji i preventivi samo su neki od razloga za ovakav prilaz rezistenciji mikroorganizama. Međutim, u proteklih nekoliko decenija, jedna od najintenzivnijih sfera istraživanja farmaceutske industrije su antivirusni preparati. Može slobodno da se kaže da se o virusima koji izazivaju oboljenja sisara praktično sve zna. Od načina replikacije, mehanizama kojima patogeno deluju na tkiva i organe, ponašanja u inficiranim ćelijama, a za neke viruse je poznat i celokupni genetski kod. Međutim, do danas je za komercijalnu upotrebu registrovano tek tridesetak preparata uz male izglede da se repertoar ovih lekova u dogledno vreme značajnije poveća. Mehanizam delovanja antivirusnih lekova najčešće je inhibicija neke virusne aktivnosti koja je neophodna da se odigra infekcija na nivou ćelije. To su inhibicija adsopcije virusa, fuzije virusa sa ćelijom, uklanjanja virusnih omotača, inhibicija virusnih enzima (virusne DNK polimeraze, reverzne transkriptaze, virusnih proteaza, neuraminidaze, dehidrogenaza i hidrolaza) kao i inhibicija sinteze virusne RNK. Pored potencijalnog značaja nastanka rezistentnih virusa u slučaju da se upotrebe antivirusni preparati kod životinja male (luksuzne) prakse, postoji i opasnost metafilaktične primene antivirusnih lekova kod onih vrsta životinja koje se koriste za ishranu ljudi, za profilaksu virusa koji izazivaju značajne zoonoze.
AB  - Especially in veterinary medicine, resistance to antimicrobial drugs is most frequently referred to
bacterial resistance to chemotherapeutics especially antibiotics that we use in order to cure bacterial diseases
in animals. Usual animal feed antibiotic supplementation, nonselective, uncontrolled and often with no reason
usage of antibiotic in therapy and prophylaxis are just some of the reasons for such approach to microorganism’s resistance. However, in last few decades development of antiviral drugs is one of the most
intensive fields of the work of the pharmaceutical industry. One can easily say that there are a few
unanswered questions as far as viruses that cause disease of mammals are concerned. As a science, virology
is aware of all aspects of virus biology and infectology. Mechanisms of the virus replication, pathogenic
pathways in infected hosts and all aspects of virus biology are well known. Moreover, for most of the
important viruses, whole genetic base has been elucidated. In spite of that, up to now there are not more than
thirty commercially registered antiviral drugs with a little chance this number to increase. Antiviral repertoire
most frequently is inhibition of some virus activity such as virus adsorption, fusion with the cell, virus
uncoating, inhibition of virus enzymes (DNA polymerase, reverse transcriptase, neuraminidase, protease,
dehydrogenase and hydrolase) as well as virus RNA replication. Apart of the potential importance as a part of
the therapy in small-luxury veterinary praxis, antivirus drugs are potential hazard if they are used as a part of
metaphylaxis in order to prevent diseases in the animal species that we use as a food. At the same time there
is a risk of virus becoming resistant in case of using antiviral drugs in the prophylaxis of the zoonoses.
PB  - Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“
T2  - Veterinarski žurnal Republike Srpske
T1  - Rezistencija na antivirusne lekove i njen značaj za veterinarsku medicinu
T1  - Antiviral drugs resistance - importance for veterinary medicine
VL  - 12
IS  - 1
SP  - 39
EP  - 46
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2096
ER  - 

@article{
author = "Valčić, Miroslav A. and Radojičić, Sonja and Bacić, Dragan and Obrenović, Sonja",
year = "2012",
abstract = "Kada se govori o rezistenciji mikroorganizama, naročito u veterinarskoj medicini, najčešće se misli na sojeve bakterija koji su otporni na hemioterapeutike, prevashodno antibiotike. Uobičajeno dodavanje antibiotika stočnoj hrani, neselektivna, nekontrolisana i često bezrazložna upotreba antibiotika u terapiji i preventivi samo su neki od razloga za ovakav prilaz rezistenciji mikroorganizama. Međutim, u proteklih nekoliko decenija, jedna od najintenzivnijih sfera istraživanja farmaceutske industrije su antivirusni preparati. Može slobodno da se kaže da se o virusima koji izazivaju oboljenja sisara praktično sve zna. Od načina replikacije, mehanizama kojima patogeno deluju na tkiva i organe, ponašanja u inficiranim ćelijama, a za neke viruse je poznat i celokupni genetski kod. Međutim, do danas je za komercijalnu upotrebu registrovano tek tridesetak preparata uz male izglede da se repertoar ovih lekova u dogledno vreme značajnije poveća. Mehanizam delovanja antivirusnih lekova najčešće je inhibicija neke virusne aktivnosti koja je neophodna da se odigra infekcija na nivou ćelije. To su inhibicija adsopcije virusa, fuzije virusa sa ćelijom, uklanjanja virusnih omotača, inhibicija virusnih enzima (virusne DNK polimeraze, reverzne transkriptaze, virusnih proteaza, neuraminidaze, dehidrogenaza i hidrolaza) kao i inhibicija sinteze virusne RNK. Pored potencijalnog značaja nastanka rezistentnih virusa u slučaju da se upotrebe antivirusni preparati kod životinja male (luksuzne) prakse, postoji i opasnost metafilaktične primene antivirusnih lekova kod onih vrsta životinja koje se koriste za ishranu ljudi, za profilaksu virusa koji izazivaju značajne zoonoze., Especially in veterinary medicine, resistance to antimicrobial drugs is most frequently referred to
bacterial resistance to chemotherapeutics especially antibiotics that we use in order to cure bacterial diseases
in animals. Usual animal feed antibiotic supplementation, nonselective, uncontrolled and often with no reason
usage of antibiotic in therapy and prophylaxis are just some of the reasons for such approach to microorganism’s resistance. However, in last few decades development of antiviral drugs is one of the most
intensive fields of the work of the pharmaceutical industry. One can easily say that there are a few
unanswered questions as far as viruses that cause disease of mammals are concerned. As a science, virology
is aware of all aspects of virus biology and infectology. Mechanisms of the virus replication, pathogenic
pathways in infected hosts and all aspects of virus biology are well known. Moreover, for most of the
important viruses, whole genetic base has been elucidated. In spite of that, up to now there are not more than
thirty commercially registered antiviral drugs with a little chance this number to increase. Antiviral repertoire
most frequently is inhibition of some virus activity such as virus adsorption, fusion with the cell, virus
uncoating, inhibition of virus enzymes (DNA polymerase, reverse transcriptase, neuraminidase, protease,
dehydrogenase and hydrolase) as well as virus RNA replication. Apart of the potential importance as a part of
the therapy in small-luxury veterinary praxis, antivirus drugs are potential hazard if they are used as a part of
metaphylaxis in order to prevent diseases in the animal species that we use as a food. At the same time there
is a risk of virus becoming resistant in case of using antiviral drugs in the prophylaxis of the zoonoses.",
publisher = "Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“",
journal = "Veterinarski žurnal Republike Srpske",
title = "Rezistencija na antivirusne lekove i njen značaj za veterinarsku medicinu, Antiviral drugs resistance - importance for veterinary medicine",
volume = "12",
number = "1",
pages = "39-46",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2096"
}

Valčić, M. A., Radojičić, S., Bacić, D.,& Obrenović, S.. (2012). Rezistencija na antivirusne lekove i njen značaj za veterinarsku medicinu. in Veterinarski žurnal Republike Srpske
Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“., 12(1), 39-46.
https://hdl.handle.net/21.15107/rcub_veterinar_2096

Valčić MA, Radojičić S, Bacić D, Obrenović S. Rezistencija na antivirusne lekove i njen značaj za veterinarsku medicinu. in Veterinarski žurnal Republike Srpske. 2012;12(1):39-46.
https://hdl.handle.net/21.15107/rcub_veterinar_2096 .

Valčić, Miroslav A., Radojičić, Sonja, Bacić, Dragan, Obrenović, Sonja, "Rezistencija na antivirusne lekove i njen značaj za veterinarsku medicinu" in Veterinarski žurnal Republike Srpske, 12, no. 1 (2012):39-46,
https://hdl.handle.net/21.15107/rcub_veterinar_2096 .

TY  - JOUR
AU  - Bacić, Dragan
AU  - Obrenović, Sonja
AU  - Kirovski, Marko
AU  - Dimitrijević, Blagoje
AU  - Radojičić, Sonja
AU  - Valčić, Miroslav
AU  - Mirilović, Milorad
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/848
AB  - The objective of these investigations was to check on laboratory white mice the protective effect of an inactivated bivalent vaccine prepared from serotypes 1/2a and 4b L. monocytogenes. Following verification of the sterility and toxicity of the prepared vaccine, the mice were divided into 6 groups with 10 animals in each group. The first and second group of mice were administered the vaccine without saponin (vaccine A) and the third and fourth group the vaccine with saponin (vaccine B). Mice of the fifth and the sixth group were not vaccinated and served as a negative control. Two weeks following vaccination, the experimental groups were revaccinated, with the exception of the two control groups. Two weeks following revaccination, all groups were artificially infected with serotypes 1/2a and 4b L. monocytogenes. During the course of the investigations (60 days) a total of 4 mice died in the vaccinated groups. Mice of the control groups started dying after day 7, and the last mouse in these groups died 14 days after the infection. Examinations of preparations of parenchymatous organs of the dead mice stained according to Gram proved the presence of L. monocytogenes. Homogenates of parenchymatous organs were sown on tryptose agar for reisolation and a pure culture of L. monocytogenes was obtained. Through the use of specific antiserums, serotypes 1/2a and 4b were confirmed. Considering the total number of vaccinated mice in the experiment and the percent deaths (10%), it can be said that the investigated vaccine with saponin had a satisfactory protective effect.
AB  - Cilj ovog istraživanja bio je da se na laboratorijskim belim miševima proveri zaštitno dejstvo inaktivisane dvovalentne vakcine pripremljene od serotipova L. monocytogenes 1/2a i 4b. Nakon provere sterilnosti i toksičnosti pripremljene vakcine miševi su podeljeni u 6 grupa sa po 10 životinja. Prva i druga grupa miševa su dobile vakcinu bez saponina (vakcina A), a treća i četvrta grupa vakcinu sa saponinom (vakcina B). Miševi pete i šeste grupe nisu vakcinisani i služili su kao negativna kontrola. Dve nedelje nakon vakcinacije izvršena je revakcinacija oglednih grupa, osim kontrolnih. Dve nedelje nakon revakcinacije izvršena je veštačka infekcija svih grupa sa serotipovima L. monocytogenes 1/2a i 4b. Za vreme ispitivanja (60 dana) uginula su 4 miša iz vakcinisanih grupa. Miševi kontrolnih grupa su počeli da uginjavaju nakon 7. dana, a poslednji miš je uginuo 14 dana posle infekcije. Pregledom preparata iz parenhimatoznih organa uginulih miševa obojenih po Gramu dokazano je prisustvo L. monocytogenes. Zasejavanjem homogenizata parenhimatoznih organa na triptozni agar urađena je reizolacija i dobijena je čista kultura L. monocytogenes. Upotrebom specifičnih antiseruma potvrđeni su serotipovi 1/2a i 4b. S obzirom na ukupan broj vakcinisanih miševa u ogledu i procenat uginuća (10%), može se reći da je ispitivana vakcina sa saponinom imala zadovoljavajuć i zaštitni efekat.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Investigations of protective effects of bivalent inactivated vaccine prepared from serotypes 1/2a and 4b Listeria monocytogenes on mice
T1  - Ispitivanje zaštitnog dejstva dvovalentne inaktivisane vakcine pripremljene od serotipova 1/2a i 4b Listeria monocytogenes na miševima
VL  - 66
IS  - 1-2
SP  - 49
EP  - 57
DO  - 10.2298/VETGL1202049B
ER  - 

@article{
author = "Bacić, Dragan and Obrenović, Sonja and Kirovski, Marko and Dimitrijević, Blagoje and Radojičić, Sonja and Valčić, Miroslav and Mirilović, Milorad",
year = "2012",
abstract = "The objective of these investigations was to check on laboratory white mice the protective effect of an inactivated bivalent vaccine prepared from serotypes 1/2a and 4b L. monocytogenes. Following verification of the sterility and toxicity of the prepared vaccine, the mice were divided into 6 groups with 10 animals in each group. The first and second group of mice were administered the vaccine without saponin (vaccine A) and the third and fourth group the vaccine with saponin (vaccine B). Mice of the fifth and the sixth group were not vaccinated and served as a negative control. Two weeks following vaccination, the experimental groups were revaccinated, with the exception of the two control groups. Two weeks following revaccination, all groups were artificially infected with serotypes 1/2a and 4b L. monocytogenes. During the course of the investigations (60 days) a total of 4 mice died in the vaccinated groups. Mice of the control groups started dying after day 7, and the last mouse in these groups died 14 days after the infection. Examinations of preparations of parenchymatous organs of the dead mice stained according to Gram proved the presence of L. monocytogenes. Homogenates of parenchymatous organs were sown on tryptose agar for reisolation and a pure culture of L. monocytogenes was obtained. Through the use of specific antiserums, serotypes 1/2a and 4b were confirmed. Considering the total number of vaccinated mice in the experiment and the percent deaths (10%), it can be said that the investigated vaccine with saponin had a satisfactory protective effect., Cilj ovog istraživanja bio je da se na laboratorijskim belim miševima proveri zaštitno dejstvo inaktivisane dvovalentne vakcine pripremljene od serotipova L. monocytogenes 1/2a i 4b. Nakon provere sterilnosti i toksičnosti pripremljene vakcine miševi su podeljeni u 6 grupa sa po 10 životinja. Prva i druga grupa miševa su dobile vakcinu bez saponina (vakcina A), a treća i četvrta grupa vakcinu sa saponinom (vakcina B). Miševi pete i šeste grupe nisu vakcinisani i služili su kao negativna kontrola. Dve nedelje nakon vakcinacije izvršena je revakcinacija oglednih grupa, osim kontrolnih. Dve nedelje nakon revakcinacije izvršena je veštačka infekcija svih grupa sa serotipovima L. monocytogenes 1/2a i 4b. Za vreme ispitivanja (60 dana) uginula su 4 miša iz vakcinisanih grupa. Miševi kontrolnih grupa su počeli da uginjavaju nakon 7. dana, a poslednji miš je uginuo 14 dana posle infekcije. Pregledom preparata iz parenhimatoznih organa uginulih miševa obojenih po Gramu dokazano je prisustvo L. monocytogenes. Zasejavanjem homogenizata parenhimatoznih organa na triptozni agar urađena je reizolacija i dobijena je čista kultura L. monocytogenes. Upotrebom specifičnih antiseruma potvrđeni su serotipovi 1/2a i 4b. S obzirom na ukupan broj vakcinisanih miševa u ogledu i procenat uginuća (10%), može se reći da je ispitivana vakcina sa saponinom imala zadovoljavajuć i zaštitni efekat.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Investigations of protective effects of bivalent inactivated vaccine prepared from serotypes 1/2a and 4b Listeria monocytogenes on mice, Ispitivanje zaštitnog dejstva dvovalentne inaktivisane vakcine pripremljene od serotipova 1/2a i 4b Listeria monocytogenes na miševima",
volume = "66",
number = "1-2",
pages = "49-57",
doi = "10.2298/VETGL1202049B"
}

Bacić, D., Obrenović, S., Kirovski, M., Dimitrijević, B., Radojičić, S., Valčić, M.,& Mirilović, M.. (2012). Investigations of protective effects of bivalent inactivated vaccine prepared from serotypes 1/2a and 4b Listeria monocytogenes on mice. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 66(1-2), 49-57.
https://doi.org/10.2298/VETGL1202049B

Bacić D, Obrenović S, Kirovski M, Dimitrijević B, Radojičić S, Valčić M, Mirilović M. Investigations of protective effects of bivalent inactivated vaccine prepared from serotypes 1/2a and 4b Listeria monocytogenes on mice. in Veterinarski Glasnik. 2012;66(1-2):49-57.
doi:10.2298/VETGL1202049B .

Bacić, Dragan, Obrenović, Sonja, Kirovski, Marko, Dimitrijević, Blagoje, Radojičić, Sonja, Valčić, Miroslav, Mirilović, Milorad, "Investigations of protective effects of bivalent inactivated vaccine prepared from serotypes 1/2a and 4b Listeria monocytogenes on mice" in Veterinarski Glasnik, 66, no. 1-2 (2012):49-57,
https://doi.org/10.2298/VETGL1202049B . .

TY  - JOUR
AU  - Jonić, Branko
AU  - Dimitrijević, Blagoje
AU  - Mirilović, Milorad
AU  - Obrenović, Sonja
AU  - Bacić, Dragan
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/858
AB  - The aim of these investigations was to examine the concentration of total proteins and total immunoglobulins in blood serum of calves and on the bases of the obtained results to evaluate the risk of their contracting a disease in the first month of life. Examinations were carried out on 23 calves maintained in farm conditions, whose medical condition was monitored in the first month of life. Blood samples were taken by puncture from the v. jugularis immediately at birth, and at 24 and 48 hours after that, and blood serum was obtained by spontaneous coaggulation. The concentration of total proteins in blood serum was determined using biuretic probe, and the immunoglobulin level using the refractometric method with the zinc-sulphate test (ZST). The average value of total proteins in calves immediately at birth was low and stood at 42±0.3 g/l. The increased concentration of total proteins in calves after the intake of colostrum is a result of the absorption of colostrum immunoglobulins. A high positive correlation was established between the concentration of total proteins and total immunoglobulins at 24 and 48 hours after birth (rxy = 0.92 and rxy = 0.75). Based on the results of monitoring the health condition and the values for total protein concentrations during the examined period (24 and 48 hours after birth) it is possible to make the following risk evaluation regarding diseases in newborn calves: 1) proteinaemia lower than 50 g/l presents a high risk; 2) proteinaemia between 50-54 g/l presents a medium risk: and, 3) proteinaemia between 55-69 g/l presents a low risk for diseases occurring in newborn calves.
AB  - Cilj ovog istraživanja bio je da se ispita koncentracija ukupnih proteina i ukupnih imunoglobulina u krvnom serumu teladi i na osnovu toga izvrši procena rizika oboljenja u prvom mesecu života. Ispitivanje je izvedeno na 23 teleta u farmskim uslovima držanja, čije je zdravstveno stanje praćeno u prvom mesecu života. Uzorci krvi uzimani su punkcijom v. jugularis neposredno po rođenju, 24. i 48. sata, a krvni serum je dobijen spontanom koagulacijom. Koncentracija ukupnih proteina u krvnom serumu određivana je biuretskom probom, a nivo imunoglobulina refraktometrijskom metodom korišćenjem cink-sulfat testa (ZST). Prosečna vrednost ukupnih proteina kod teladi neposredno po rođenju bila je niska i iznosila je 42 ± 0,3 g/l. Povećanje koncentracije ukupnih proteina kod teladi nakon unošenja kolostruma rezultat je apsorpcije kolostralnih imunoglobulina. Visoka pozitivna korelacija utvrđ ena je između koncentracije ukupnih proteina i ukupnih imunoglobulina u periodu 24. i 48. sata po rođenju (rxy=0,92 i rxy = 0,75). Na osnovu rezultata praćenja zdravstvenog stanja i vrednosti koncentracije ukupnih proteina u ispitivanom periodu (24-og i 48-og sata) moguć e je dati sledeću procenu rizika oboljenja novorođene teladi: 1) proteinemija manja od 50 g/l odgovara visokom riziku; 2) proteinemija između 50 i 54 g/l odgovara srednjem riziku i 3) proteinemija između 55 i 69 g/l odgovara malom riziku za pojavu oboljenja novorođene teladi.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Evaluation of colostrum protection of calves
T1  - Procena kolostralne zaštite teladi
VL  - 66
IS  - 1-2
SP  - 13
EP  - 25
DO  - 10.2298/VETGL1202013J
ER  - 

@article{
author = "Jonić, Branko and Dimitrijević, Blagoje and Mirilović, Milorad and Obrenović, Sonja and Bacić, Dragan",
year = "2012",
abstract = "The aim of these investigations was to examine the concentration of total proteins and total immunoglobulins in blood serum of calves and on the bases of the obtained results to evaluate the risk of their contracting a disease in the first month of life. Examinations were carried out on 23 calves maintained in farm conditions, whose medical condition was monitored in the first month of life. Blood samples were taken by puncture from the v. jugularis immediately at birth, and at 24 and 48 hours after that, and blood serum was obtained by spontaneous coaggulation. The concentration of total proteins in blood serum was determined using biuretic probe, and the immunoglobulin level using the refractometric method with the zinc-sulphate test (ZST). The average value of total proteins in calves immediately at birth was low and stood at 42±0.3 g/l. The increased concentration of total proteins in calves after the intake of colostrum is a result of the absorption of colostrum immunoglobulins. A high positive correlation was established between the concentration of total proteins and total immunoglobulins at 24 and 48 hours after birth (rxy = 0.92 and rxy = 0.75). Based on the results of monitoring the health condition and the values for total protein concentrations during the examined period (24 and 48 hours after birth) it is possible to make the following risk evaluation regarding diseases in newborn calves: 1) proteinaemia lower than 50 g/l presents a high risk; 2) proteinaemia between 50-54 g/l presents a medium risk: and, 3) proteinaemia between 55-69 g/l presents a low risk for diseases occurring in newborn calves., Cilj ovog istraživanja bio je da se ispita koncentracija ukupnih proteina i ukupnih imunoglobulina u krvnom serumu teladi i na osnovu toga izvrši procena rizika oboljenja u prvom mesecu života. Ispitivanje je izvedeno na 23 teleta u farmskim uslovima držanja, čije je zdravstveno stanje praćeno u prvom mesecu života. Uzorci krvi uzimani su punkcijom v. jugularis neposredno po rođenju, 24. i 48. sata, a krvni serum je dobijen spontanom koagulacijom. Koncentracija ukupnih proteina u krvnom serumu određivana je biuretskom probom, a nivo imunoglobulina refraktometrijskom metodom korišćenjem cink-sulfat testa (ZST). Prosečna vrednost ukupnih proteina kod teladi neposredno po rođenju bila je niska i iznosila je 42 ± 0,3 g/l. Povećanje koncentracije ukupnih proteina kod teladi nakon unošenja kolostruma rezultat je apsorpcije kolostralnih imunoglobulina. Visoka pozitivna korelacija utvrđ ena je između koncentracije ukupnih proteina i ukupnih imunoglobulina u periodu 24. i 48. sata po rođenju (rxy=0,92 i rxy = 0,75). Na osnovu rezultata praćenja zdravstvenog stanja i vrednosti koncentracije ukupnih proteina u ispitivanom periodu (24-og i 48-og sata) moguć e je dati sledeću procenu rizika oboljenja novorođene teladi: 1) proteinemija manja od 50 g/l odgovara visokom riziku; 2) proteinemija između 50 i 54 g/l odgovara srednjem riziku i 3) proteinemija između 55 i 69 g/l odgovara malom riziku za pojavu oboljenja novorođene teladi.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Evaluation of colostrum protection of calves, Procena kolostralne zaštite teladi",
volume = "66",
number = "1-2",
pages = "13-25",
doi = "10.2298/VETGL1202013J"
}

Jonić, B., Dimitrijević, B., Mirilović, M., Obrenović, S.,& Bacić, D.. (2012). Evaluation of colostrum protection of calves. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 66(1-2), 13-25.
https://doi.org/10.2298/VETGL1202013J

Jonić B, Dimitrijević B, Mirilović M, Obrenović S, Bacić D. Evaluation of colostrum protection of calves. in Veterinarski Glasnik. 2012;66(1-2):13-25.
doi:10.2298/VETGL1202013J .

Jonić, Branko, Dimitrijević, Blagoje, Mirilović, Milorad, Obrenović, Sonja, Bacić, Dragan, "Evaluation of colostrum protection of calves" in Veterinarski Glasnik, 66, no. 1-2 (2012):13-25,
https://doi.org/10.2298/VETGL1202013J . .

TY  - JOUR
AU  - Bacić, Dragan
AU  - Obrenović, Sonja
AU  - Dimitrijević, B.
AU  - Jonić, B.
AU  - Žutić, Jadranka
AU  - Ašanin, N.
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/944
AB  - In this study, the protective effects of two bivalent inactivated vaccines were evaluated. Vaccines were prepared from Listeria monocytogenes, serotypes 1/2a and 4b, as the most frequent in our and surrounding epidemiological areas. Vaccine A consists of whole L. monocytogenes bacteria cells, inactivated with 0.4% formaldehyde and aluminium hydroxide as a carrier. Vaccine B contains 0.1% saponin in addition to ingredients of vaccine A. Evaluations of these vaccines were performed in 60 sheep, divided into four groups (n=10) with a corresponding negative control group (n=5). After 14 days, boosterisation of all animals was performed. In order to evaluate the immune response, blood samples were obtained every 14 days during the next 6 months. Antibody titres were determined by microaglutitation (MAT) and complement fixation tests (CFT). Comparative analyses of antibody titres, induced by vaccines A and B, show that the latter (with saponine) significantly increased the level of antibody titres (p lt 0.01). The levels of immune response were also significantly impacted by the total number of bacteria and vaccine dosage (p lt 0.01). The bivalent vaccine containing 0.1% saponin (vaccine B) in 5.0 mLx 106 cfu/mL (colony-forming units per milliliter) dosage shows a protective effect after challenge with L. monocytogenes. The protective levels of this antibody were 1/80 and 1/16, determined by MAT and CFT, respectively. Antibody titres were significantly higher after boosterisation (p lt 0.01) and protective levels could be detected in the sera of vaccinated animals during the next 6 months. Therefore, it is strongly recommended to perform boosterisation two weeks after the initial vaccination.
AB  - U ovom radu ispitivano je protektivno dejstvo eksperimentalno inaktivisane dvovalentne vakcine protiv listerioze ovaca.Vakcina je pripremana od sojeva L. monocytogenes 1/2a i 4b koji su najzastupljeniji na našem epizootiološkom području i u zemljama u okruženju. Vakcina A sadrži cele bakterijske ćelije koje su inaktivisane 0,4% formalinom uz dodatak aluminijum hidroksida kao nosača. Vakcina B pored gore navedenih sastojaka sadrži i 0,1% saponina. Ispitivanje ovako pripremljene eksperimentalne inaktivisane bivalentne vakcine protiv listerioze ovaca izvedeno je na 60 ovaca podeljenih u 4 grupe (n=10), pri čemu je svaka grupa imala kontrolnu grupu (n=5). Nakon 14 dana urađena je revakcinacija svih oglednih životinja. Krv je uzorkovana svakih 14 dana, tokom narednih 6 meseci i praćeno je kretanje titra antitela, metodom spore aglutinacije (MAT) i reakcijom vezivanja komplementa (RVK). Uporednim ispitivanjem visine titra antitela kod životinja koje su imunizovane vakcinom bez saponina i vakcinom sa 0,1% saponina ustanovljeno je da saponin značajno podstiče imunski odgovor. Ustanovljeno je da ukupan broj mikrooganizama u vakcini, kao i doza vakcine, utiču na kvalitet imunskog odgovora. Utvrđen je viši titar antitela ako se aplikuje doza vakcine od 5,0 ml × 106 cfu/ml nego kada je aplikovana doza od 2,5 ml × 106 cfu/ml (p lt 0,01). Dvovalentna vakcina pripremljena od inaktivisanih serotipova listerija sa saponinom u dozi od 5,0 ml × 106ml štitila je jagnjad od veštačke infekcije, a protektivni titar iznosio je 1:80 utvrđen metodom mikroaglutinacije, odnosno 1:16 metodom reakcije vezivanja komlementa. Titri antitela nakon revakcinacije su značajno viši nego posle prve vakcinacije (p,01) i mogli su da se otkriju u serumu životinja 6 meseci nakon vakcinacije, zbog čega se preporučuje obavezna revakcinacija 2 nedelje nakon vakcinacije.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - A study on the inactivated bivalent vaccine prepared from serotypes 1/2a and 4b Listeria monocytogenes for the control of listeriosis in sheep
T1  - Ispitivanje inaktivisane dvovalentne vakcine pripremljene od serotipova 1/2a i 4b Listeria monocytogenes u kontroli listerioze kod ovaca
VL  - 62
IS  - 5-6
SP  - 531
EP  - 541
DO  - 10.2298/AVB1206531B
ER  - 

@article{
author = "Bacić, Dragan and Obrenović, Sonja and Dimitrijević, B. and Jonić, B. and Žutić, Jadranka and Ašanin, N.",
year = "2012",
abstract = "In this study, the protective effects of two bivalent inactivated vaccines were evaluated. Vaccines were prepared from Listeria monocytogenes, serotypes 1/2a and 4b, as the most frequent in our and surrounding epidemiological areas. Vaccine A consists of whole L. monocytogenes bacteria cells, inactivated with 0.4% formaldehyde and aluminium hydroxide as a carrier. Vaccine B contains 0.1% saponin in addition to ingredients of vaccine A. Evaluations of these vaccines were performed in 60 sheep, divided into four groups (n=10) with a corresponding negative control group (n=5). After 14 days, boosterisation of all animals was performed. In order to evaluate the immune response, blood samples were obtained every 14 days during the next 6 months. Antibody titres were determined by microaglutitation (MAT) and complement fixation tests (CFT). Comparative analyses of antibody titres, induced by vaccines A and B, show that the latter (with saponine) significantly increased the level of antibody titres (p lt 0.01). The levels of immune response were also significantly impacted by the total number of bacteria and vaccine dosage (p lt 0.01). The bivalent vaccine containing 0.1% saponin (vaccine B) in 5.0 mLx 106 cfu/mL (colony-forming units per milliliter) dosage shows a protective effect after challenge with L. monocytogenes. The protective levels of this antibody were 1/80 and 1/16, determined by MAT and CFT, respectively. Antibody titres were significantly higher after boosterisation (p lt 0.01) and protective levels could be detected in the sera of vaccinated animals during the next 6 months. Therefore, it is strongly recommended to perform boosterisation two weeks after the initial vaccination., U ovom radu ispitivano je protektivno dejstvo eksperimentalno inaktivisane dvovalentne vakcine protiv listerioze ovaca.Vakcina je pripremana od sojeva L. monocytogenes 1/2a i 4b koji su najzastupljeniji na našem epizootiološkom području i u zemljama u okruženju. Vakcina A sadrži cele bakterijske ćelije koje su inaktivisane 0,4% formalinom uz dodatak aluminijum hidroksida kao nosača. Vakcina B pored gore navedenih sastojaka sadrži i 0,1% saponina. Ispitivanje ovako pripremljene eksperimentalne inaktivisane bivalentne vakcine protiv listerioze ovaca izvedeno je na 60 ovaca podeljenih u 4 grupe (n=10), pri čemu je svaka grupa imala kontrolnu grupu (n=5). Nakon 14 dana urađena je revakcinacija svih oglednih životinja. Krv je uzorkovana svakih 14 dana, tokom narednih 6 meseci i praćeno je kretanje titra antitela, metodom spore aglutinacije (MAT) i reakcijom vezivanja komplementa (RVK). Uporednim ispitivanjem visine titra antitela kod životinja koje su imunizovane vakcinom bez saponina i vakcinom sa 0,1% saponina ustanovljeno je da saponin značajno podstiče imunski odgovor. Ustanovljeno je da ukupan broj mikrooganizama u vakcini, kao i doza vakcine, utiču na kvalitet imunskog odgovora. Utvrđen je viši titar antitela ako se aplikuje doza vakcine od 5,0 ml × 106 cfu/ml nego kada je aplikovana doza od 2,5 ml × 106 cfu/ml (p lt 0,01). Dvovalentna vakcina pripremljena od inaktivisanih serotipova listerija sa saponinom u dozi od 5,0 ml × 106ml štitila je jagnjad od veštačke infekcije, a protektivni titar iznosio je 1:80 utvrđen metodom mikroaglutinacije, odnosno 1:16 metodom reakcije vezivanja komlementa. Titri antitela nakon revakcinacije su značajno viši nego posle prve vakcinacije (p,01) i mogli su da se otkriju u serumu životinja 6 meseci nakon vakcinacije, zbog čega se preporučuje obavezna revakcinacija 2 nedelje nakon vakcinacije.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "A study on the inactivated bivalent vaccine prepared from serotypes 1/2a and 4b Listeria monocytogenes for the control of listeriosis in sheep, Ispitivanje inaktivisane dvovalentne vakcine pripremljene od serotipova 1/2a i 4b Listeria monocytogenes u kontroli listerioze kod ovaca",
volume = "62",
number = "5-6",
pages = "531-541",
doi = "10.2298/AVB1206531B"
}

Bacić, D., Obrenović, S., Dimitrijević, B., Jonić, B., Žutić, J.,& Ašanin, N.. (2012). A study on the inactivated bivalent vaccine prepared from serotypes 1/2a and 4b Listeria monocytogenes for the control of listeriosis in sheep. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 62(5-6), 531-541.
https://doi.org/10.2298/AVB1206531B

Bacić D, Obrenović S, Dimitrijević B, Jonić B, Žutić J, Ašanin N. A study on the inactivated bivalent vaccine prepared from serotypes 1/2a and 4b Listeria monocytogenes for the control of listeriosis in sheep. in Acta Veterinaria-Beograd. 2012;62(5-6):531-541.
doi:10.2298/AVB1206531B .

Bacić, Dragan, Obrenović, Sonja, Dimitrijević, B., Jonić, B., Žutić, Jadranka, Ašanin, N., "A study on the inactivated bivalent vaccine prepared from serotypes 1/2a and 4b Listeria monocytogenes for the control of listeriosis in sheep" in Acta Veterinaria-Beograd, 62, no. 5-6 (2012):531-541,
https://doi.org/10.2298/AVB1206531B . .