TY  - JOUR
AU  - Bajagić, Bojana
AU  - Mrkun, Janko
AU  - Kirovski, Danijela
AU  - Savić, Đorđe
AU  - Budimir, Draženko
AU  - Maletić, Jelena
AU  - Maletić, Milan
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2327
AB  - diagnoses and their accuracy to predict pregnancy. The study was performed on 51
postpartum cross breed dairy cows with pathological puerperium. Artificial insemination
(AI) was done in spontaneous estrus. Endometrium samples were taken by cytotape
(CT), cervical mucus (CM) samples by Metricheck and smears for crystallization degree
were obtained at AI day. Blood serum samples for progesterone (P4) concentration
determination were taken at AI day and 17 days later. Cows were examined by
ultrasound 35 days after AI to confirm pregnancy. Percent (%) of polymorphnuclear
leukocytes (PMNs) taken by CT were expressed by ROC curve (with cut-off point set
at 1%). Out of the total of 51 cows involved in the study, 13.73% true positive and
41.17% true negative cows were found (54.90%). The content of CM sampled with
Metricheck was altered in 11 cows (21.57%), and one of them was pregnant (1.96%).
An average macroscopic CM value for pregnant cows was 0.06±0.24 vs. 0.39±0.79
for non-pregnant (p<0.05). An average value of CM crystallization in pregnant cows
was 2.50±1.04 vs. 1.85±1.15 in non-pregnant (p<0.05). P4 concentration was not
statistically different at AI day, but was statistically significantly higher 17 days later
in pregnant cows (p = 0.002). CT alterations may be a reliable diagnostic tool for
SCE diagnosis, while macroscopic CM alterations may be used for CE detection. P4
determination is beneficial in pregnancy diagnosis while CM crystallization degree is
helpful in determination of best time for AI.
AB  - Cilj studije bio je procena različitih metoda za dijagnostiku supkliničkog endometritisa
(SKE) i njihove pouzdanosti za predviđanje graviditeta. U studiju je bila uključena 51
postpartalna mlečna krava mešane rase sa patološkim puerperijem. Veštačko osemenjavanje
(VO) rađeno je u spontanom estrusu. Na dan VO uzeti su uzorci endometrijuma
dobijeni cytotape (CT) tehnikom, kao i uzorci cervikalne sluzi (CS) dobijeni
upotrebom Metričeka. Razmaz CS, urađen isti dan, korišten je za ispitivanje stepena
kristalizacije. Uzorci krvi za određivanje koncentracije progesterona (P4) uzeti su na
dan VO i 17 dana kasnije. Krave su pregledane ultrazvukom 35 dana nakon VO radi
potvrđivanja graviditeta. Procenat (%) polimorfonuklearnih leukocita (PMNs) dobijenih CT tehnikom je izražen ROC krivom (granična vrednost je određena na 1%).
Od ukupno 54,90% krava uključenih u studiju, utvrđeno je 13,73% stvarno pozitivnih
i 41,17% stvarno negativnih krava. Izmenjen sadržaj CS uzorkovane Metričekom
utvrđen je kod jedanaest krava (21,57%), ali samo jedna (1,96%) je bila gravidna. Prosečna
makroskopska vrednost CS kod gravidnih krava je bila 0,06±0,24 u odnosu na
0,39±0,79 kod negravidnih (p<0,05). Prosečna vrednost kristalizacije CS kod gravidnih
krava je bila 2,50±1,04 u odnosu na 1,85±1,15 kod negravidnih (p<0,05). Koncentracija
P4 nije se statistički razlikovala na dan VO, ali je bila statistički značajno
veća 17 dana kasnije kod gravidnih životinja (p = 0.002). Promene utvrđene CT mogu
biti indikator SKE, a promene CS dobijene Metričekom mogu biti indikator kliničkog
endometritisa. Određivanje P4 korisno je u dijagnostici graviditeta, a kristalizacija CS
može se koristiti kao pomoćni metod za određivanje najpovoljnijeg vremena za VO.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria-Beograd
T1  - Assessment of different diagnostic methods for the identification of subclinical endometritis in dairy cows with pathological puerperium and their reliability to conceive
T1  - Procena različitih dijagnostičkih metoda za identifikaciju supkliničkog endometritisa mlečnih krava sa patološkim puerperijumom i njihova pouzdanost u predikciji graviditeta
VL  - 71
IS  - 4
SP  - 462
EP  - 476
DO  - 10.2478/acve-2021-0038
ER  - 

@article{
author = "Bajagić, Bojana and Mrkun, Janko and Kirovski, Danijela and Savić, Đorđe and Budimir, Draženko and Maletić, Jelena and Maletić, Milan",
year = "2021",
abstract = "diagnoses and their accuracy to predict pregnancy. The study was performed on 51
postpartum cross breed dairy cows with pathological puerperium. Artificial insemination
(AI) was done in spontaneous estrus. Endometrium samples were taken by cytotape
(CT), cervical mucus (CM) samples by Metricheck and smears for crystallization degree
were obtained at AI day. Blood serum samples for progesterone (P4) concentration
determination were taken at AI day and 17 days later. Cows were examined by
ultrasound 35 days after AI to confirm pregnancy. Percent (%) of polymorphnuclear
leukocytes (PMNs) taken by CT were expressed by ROC curve (with cut-off point set
at 1%). Out of the total of 51 cows involved in the study, 13.73% true positive and
41.17% true negative cows were found (54.90%). The content of CM sampled with
Metricheck was altered in 11 cows (21.57%), and one of them was pregnant (1.96%).
An average macroscopic CM value for pregnant cows was 0.06±0.24 vs. 0.39±0.79
for non-pregnant (p<0.05). An average value of CM crystallization in pregnant cows
was 2.50±1.04 vs. 1.85±1.15 in non-pregnant (p<0.05). P4 concentration was not
statistically different at AI day, but was statistically significantly higher 17 days later
in pregnant cows (p = 0.002). CT alterations may be a reliable diagnostic tool for
SCE diagnosis, while macroscopic CM alterations may be used for CE detection. P4
determination is beneficial in pregnancy diagnosis while CM crystallization degree is
helpful in determination of best time for AI., Cilj studije bio je procena različitih metoda za dijagnostiku supkliničkog endometritisa
(SKE) i njihove pouzdanosti za predviđanje graviditeta. U studiju je bila uključena 51
postpartalna mlečna krava mešane rase sa patološkim puerperijem. Veštačko osemenjavanje
(VO) rađeno je u spontanom estrusu. Na dan VO uzeti su uzorci endometrijuma
dobijeni cytotape (CT) tehnikom, kao i uzorci cervikalne sluzi (CS) dobijeni
upotrebom Metričeka. Razmaz CS, urađen isti dan, korišten je za ispitivanje stepena
kristalizacije. Uzorci krvi za određivanje koncentracije progesterona (P4) uzeti su na
dan VO i 17 dana kasnije. Krave su pregledane ultrazvukom 35 dana nakon VO radi
potvrđivanja graviditeta. Procenat (%) polimorfonuklearnih leukocita (PMNs) dobijenih CT tehnikom je izražen ROC krivom (granična vrednost je određena na 1%).
Od ukupno 54,90% krava uključenih u studiju, utvrđeno je 13,73% stvarno pozitivnih
i 41,17% stvarno negativnih krava. Izmenjen sadržaj CS uzorkovane Metričekom
utvrđen je kod jedanaest krava (21,57%), ali samo jedna (1,96%) je bila gravidna. Prosečna
makroskopska vrednost CS kod gravidnih krava je bila 0,06±0,24 u odnosu na
0,39±0,79 kod negravidnih (p<0,05). Prosečna vrednost kristalizacije CS kod gravidnih
krava je bila 2,50±1,04 u odnosu na 1,85±1,15 kod negravidnih (p<0,05). Koncentracija
P4 nije se statistički razlikovala na dan VO, ali je bila statistički značajno
veća 17 dana kasnije kod gravidnih životinja (p = 0.002). Promene utvrđene CT mogu
biti indikator SKE, a promene CS dobijene Metričekom mogu biti indikator kliničkog
endometritisa. Određivanje P4 korisno je u dijagnostici graviditeta, a kristalizacija CS
može se koristiti kao pomoćni metod za određivanje najpovoljnijeg vremena za VO.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria-Beograd",
title = "Assessment of different diagnostic methods for the identification of subclinical endometritis in dairy cows with pathological puerperium and their reliability to conceive, Procena različitih dijagnostičkih metoda za identifikaciju supkliničkog endometritisa mlečnih krava sa patološkim puerperijumom i njihova pouzdanost u predikciji graviditeta",
volume = "71",
number = "4",
pages = "462-476",
doi = "10.2478/acve-2021-0038"
}

Bajagić, B., Mrkun, J., Kirovski, D., Savić, Đ., Budimir, D., Maletić, J.,& Maletić, M.. (2021). Assessment of different diagnostic methods for the identification of subclinical endometritis in dairy cows with pathological puerperium and their reliability to conceive. in Acta veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 71(4), 462-476.
https://doi.org/10.2478/acve-2021-0038

Bajagić B, Mrkun J, Kirovski D, Savić Đ, Budimir D, Maletić J, Maletić M. Assessment of different diagnostic methods for the identification of subclinical endometritis in dairy cows with pathological puerperium and their reliability to conceive. in Acta veterinaria-Beograd. 2021;71(4):462-476.
doi:10.2478/acve-2021-0038 .

Bajagić, Bojana, Mrkun, Janko, Kirovski, Danijela, Savić, Đorđe, Budimir, Draženko, Maletić, Jelena, Maletić, Milan, "Assessment of different diagnostic methods for the identification of subclinical endometritis in dairy cows with pathological puerperium and their reliability to conceive" in Acta veterinaria-Beograd, 71, no. 4 (2021):462-476,
https://doi.org/10.2478/acve-2021-0038 . .

TY  - JOUR
AU  - Trifković, Julijana
AU  - Jovanović, Ljubomir
AU  - Bošnjaković, Dušan
AU  - Savić, Đorđe
AU  - Stefanović, Srđan
AU  - Krajišnik, Tatjana
AU  - Sladojević, Željko
AU  - Kirovski, Danijela
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2272
AB  - This study examines the effect of season-related heat stress in dams on mineral status, and hematological profile of their calves. Ten Holstein dams (LowT group) were exposed to the 49-day-long period of low air temperature (5.2 ± 0.5 °C) and ten dams (HighT group) were exposed to a 53-day-long high air temperature (27.4 ± 0.4 °C). The dams' blood samples were taken one hour after parturition, while colostrum was sampled at 2, 14, and 26 h after calving. Ca, P, Mg, Na, K, Fe, Zn, Mn, and Se concentrations were significantly lower while Cu and Co concentrations were significantly higher at least in two examined colostrum sampling points in HighT group. Calf`s blood samples were taken before 1st colostrum intake, and on days 1, 2, 3, and 7 postnatal. Ca, P, Na, K, Fe, Cu, Zn, Mn, Se, and Co were significantly lower while concentration of Mg was significantly higher in calves that originated from HighT group at least at two examined sampling points. Season affected dam's blood mineral status but the pattern was not always the same as in calves, since Na, K, Cu, and Co were significantly higher in HighT group. Calves that originated from HighT group had significantly lower hemoglobin, hematocrit, MCV, MCH, and MPV values, as well as neutrophils and monocyte counts, while platelets, eosinophils, basophils, and lymphocyte counts were significantly higher. Season-related heat stress leads to a reduction of the most minerals in both dams' colostrum and calves' blood and certain minerals' deficiencies are linked to impaired calves' hematological adaptation.
PB  - Springer
T2  - Biological Trace Element Research
T1  - Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile
SP  - 1
EP  - 13
DO  - 10.1007/s12011-021-02834-8
ER  - 

@article{
author = "Trifković, Julijana and Jovanović, Ljubomir and Bošnjaković, Dušan and Savić, Đorđe and Stefanović, Srđan and Krajišnik, Tatjana and Sladojević, Željko and Kirovski, Danijela",
year = "2021",
abstract = "This study examines the effect of season-related heat stress in dams on mineral status, and hematological profile of their calves. Ten Holstein dams (LowT group) were exposed to the 49-day-long period of low air temperature (5.2 ± 0.5 °C) and ten dams (HighT group) were exposed to a 53-day-long high air temperature (27.4 ± 0.4 °C). The dams' blood samples were taken one hour after parturition, while colostrum was sampled at 2, 14, and 26 h after calving. Ca, P, Mg, Na, K, Fe, Zn, Mn, and Se concentrations were significantly lower while Cu and Co concentrations were significantly higher at least in two examined colostrum sampling points in HighT group. Calf`s blood samples were taken before 1st colostrum intake, and on days 1, 2, 3, and 7 postnatal. Ca, P, Na, K, Fe, Cu, Zn, Mn, Se, and Co were significantly lower while concentration of Mg was significantly higher in calves that originated from HighT group at least at two examined sampling points. Season affected dam's blood mineral status but the pattern was not always the same as in calves, since Na, K, Cu, and Co were significantly higher in HighT group. Calves that originated from HighT group had significantly lower hemoglobin, hematocrit, MCV, MCH, and MPV values, as well as neutrophils and monocyte counts, while platelets, eosinophils, basophils, and lymphocyte counts were significantly higher. Season-related heat stress leads to a reduction of the most minerals in both dams' colostrum and calves' blood and certain minerals' deficiencies are linked to impaired calves' hematological adaptation.",
publisher = "Springer",
journal = "Biological Trace Element Research",
title = "Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile",
pages = "1-13",
doi = "10.1007/s12011-021-02834-8"
}

Trifković, J., Jovanović, L., Bošnjaković, D., Savić, Đ., Stefanović, S., Krajišnik, T., Sladojević, Ž.,& Kirovski, D.. (2021). Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile. in Biological Trace Element Research
Springer., 1-13.
https://doi.org/10.1007/s12011-021-02834-8

Trifković J, Jovanović L, Bošnjaković D, Savić Đ, Stefanović S, Krajišnik T, Sladojević Ž, Kirovski D. Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile. in Biological Trace Element Research. 2021;:1-13.
doi:10.1007/s12011-021-02834-8 .

Trifković, Julijana, Jovanović, Ljubomir, Bošnjaković, Dušan, Savić, Đorđe, Stefanović, Srđan, Krajišnik, Tatjana, Sladojević, Željko, Kirovski, Danijela, "Summer Season-Related Heat Stress Affects the Mineral Composition of Holstein Dams’ Colostrum, and Neonatal Calves’ Mineral Status and Hematological Profile" in Biological Trace Element Research (2021):1-13,
https://doi.org/10.1007/s12011-021-02834-8 . .

TY  - CONF
AU  - Savić, Mila
AU  - Dimitrijević, Vladimir
AU  - Savić, Đorđe
AU  - Becskei, Zsolt
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2822
AB  - Considering that intensive livestock production systems exceed environmental limits, the framework of Republic Project 2011-2019 was focused to stimulating sustainable animal food production in hilly mountain regions of Serbia. These regions are characterised by a great capacity of environmental sustainability, such are biodiversity, pasture and water quality. The priority area of the Project is related with healthier and more sustainable lamb meat production. The lamb meat quality characteristics of well adapted autochthonous types of Zackel sheep have been evaluated. The results of this study showed that tested lamb meat samples from pasture fed Zackel sheep types contain favorable fatty acid profile and amounts of conjugated linoleic acid, important for healthy children diet, especially regarding it´s protective effects on some diseases, such are malignancies, cardiovascular diseases and diabetes. The results of this study have an implication on future promoting of sustainable lamb meat production and consumption. Also, the obtained results are a good base for improving knowledge of environmental impacts on animal food.
PB  - European Center of Sustainable Development
C3  - 7th International Conference On Sustainable Development ICSD 2019, Rome, Italy, 4 - 5 September, 2019
T1  - Stimulating of health and sustainable lamb meat production in hilly mountain regions of Serbia
SP  - 138
EP  - 138
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2822
ER  - 

@conference{
author = "Savić, Mila and Dimitrijević, Vladimir and Savić, Đorđe and Becskei, Zsolt",
year = "2019",
abstract = "Considering that intensive livestock production systems exceed environmental limits, the framework of Republic Project 2011-2019 was focused to stimulating sustainable animal food production in hilly mountain regions of Serbia. These regions are characterised by a great capacity of environmental sustainability, such are biodiversity, pasture and water quality. The priority area of the Project is related with healthier and more sustainable lamb meat production. The lamb meat quality characteristics of well adapted autochthonous types of Zackel sheep have been evaluated. The results of this study showed that tested lamb meat samples from pasture fed Zackel sheep types contain favorable fatty acid profile and amounts of conjugated linoleic acid, important for healthy children diet, especially regarding it´s protective effects on some diseases, such are malignancies, cardiovascular diseases and diabetes. The results of this study have an implication on future promoting of sustainable lamb meat production and consumption. Also, the obtained results are a good base for improving knowledge of environmental impacts on animal food.",
publisher = "European Center of Sustainable Development",
journal = "7th International Conference On Sustainable Development ICSD 2019, Rome, Italy, 4 - 5 September, 2019",
title = "Stimulating of health and sustainable lamb meat production in hilly mountain regions of Serbia",
pages = "138-138",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2822"
}

Savić, M., Dimitrijević, V., Savić, Đ.,& Becskei, Z.. (2019). Stimulating of health and sustainable lamb meat production in hilly mountain regions of Serbia. in 7th International Conference On Sustainable Development ICSD 2019, Rome, Italy, 4 - 5 September, 2019
European Center of Sustainable Development., 138-138.
https://hdl.handle.net/21.15107/rcub_veterinar_2822

Savić M, Dimitrijević V, Savić Đ, Becskei Z. Stimulating of health and sustainable lamb meat production in hilly mountain regions of Serbia. in 7th International Conference On Sustainable Development ICSD 2019, Rome, Italy, 4 - 5 September, 2019. 2019;:138-138.
https://hdl.handle.net/21.15107/rcub_veterinar_2822 .

Savić, Mila, Dimitrijević, Vladimir, Savić, Đorđe, Becskei, Zsolt, "Stimulating of health and sustainable lamb meat production in hilly mountain regions of Serbia" in 7th International Conference On Sustainable Development ICSD 2019, Rome, Italy, 4 - 5 September, 2019 (2019):138-138,
https://hdl.handle.net/21.15107/rcub_veterinar_2822 .

TY  - JOUR
AU  - Ivanović, Saša
AU  - Dimitrijević, Blagoje
AU  - Ćupić, Vitomir
AU  - Jezdimirović, Milanka
AU  - Borozan, Sunčica
AU  - Savić, Mila
AU  - Savić, Đorđe
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1347
AB  - Diazinon (DZN) is an organophosphate insecticide which exerts its effect through the inhibition of acetyl cholinesterase enzyme (AChE). In this work, we studied the development of tolerance to subchronic p.o. administration of DZN in rats, under both in vivo and in vitro conditions. A group of 20 rats (2 groups, n = 10) was administered p.o. the 1/10 of established LD50 DZN (namely 55.87 mg/kg bw) for 28 days. On the 14th and 28th day of study with isolated diaphragm and ileum, we examined the downregulation of nicotinic and muscarinic receptor function through Electrical Field Stimulation (EFS). Maximum contractility of the diaphragm was recorded on the 14th day of the study (25% higher compared to the non-treated rats), while on the 28th day the contractions almost did not differ from the values found in non-treated rats. EFS of isolated ileum on the 14th day of study caused significantly higher contractions compared to the non treated rats, but after 28 days, ileum contractions decreased approximately to the level of contractions in non-treated rats. On the 14th study day, we also recorded increased amplitude of spontaneous ileum contractions, compared to non-treated rats. The application of increasing ACh concentrations caused dose-dependent ileum contractions, without statistically significant differences of median effective concentration (EC50) values in non-treated and treated rats. Tolerance to subchronic DZN administration develops due to various adaptation mechanisms, including the most important one downregulation of nicotinic and muscarinic receptor function.
PB  - Elsevier Science Bv, Amsterdam
T2  - Toxicology Reports
T1  - Downregulation of nicotinic and muscarinic receptor function in rats after subchronic exposure to diazinon
VL  - 3
SP  - 523
EP  - 530
DO  - 10.1016/j.toxrep.2016.06.002
ER  - 

@article{
author = "Ivanović, Saša and Dimitrijević, Blagoje and Ćupić, Vitomir and Jezdimirović, Milanka and Borozan, Sunčica and Savić, Mila and Savić, Đorđe",
year = "2016",
abstract = "Diazinon (DZN) is an organophosphate insecticide which exerts its effect through the inhibition of acetyl cholinesterase enzyme (AChE). In this work, we studied the development of tolerance to subchronic p.o. administration of DZN in rats, under both in vivo and in vitro conditions. A group of 20 rats (2 groups, n = 10) was administered p.o. the 1/10 of established LD50 DZN (namely 55.87 mg/kg bw) for 28 days. On the 14th and 28th day of study with isolated diaphragm and ileum, we examined the downregulation of nicotinic and muscarinic receptor function through Electrical Field Stimulation (EFS). Maximum contractility of the diaphragm was recorded on the 14th day of the study (25% higher compared to the non-treated rats), while on the 28th day the contractions almost did not differ from the values found in non-treated rats. EFS of isolated ileum on the 14th day of study caused significantly higher contractions compared to the non treated rats, but after 28 days, ileum contractions decreased approximately to the level of contractions in non-treated rats. On the 14th study day, we also recorded increased amplitude of spontaneous ileum contractions, compared to non-treated rats. The application of increasing ACh concentrations caused dose-dependent ileum contractions, without statistically significant differences of median effective concentration (EC50) values in non-treated and treated rats. Tolerance to subchronic DZN administration develops due to various adaptation mechanisms, including the most important one downregulation of nicotinic and muscarinic receptor function.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Toxicology Reports",
title = "Downregulation of nicotinic and muscarinic receptor function in rats after subchronic exposure to diazinon",
volume = "3",
pages = "523-530",
doi = "10.1016/j.toxrep.2016.06.002"
}

Ivanović, S., Dimitrijević, B., Ćupić, V., Jezdimirović, M., Borozan, S., Savić, M.,& Savić, Đ.. (2016). Downregulation of nicotinic and muscarinic receptor function in rats after subchronic exposure to diazinon. in Toxicology Reports
Elsevier Science Bv, Amsterdam., 3, 523-530.
https://doi.org/10.1016/j.toxrep.2016.06.002

Ivanović S, Dimitrijević B, Ćupić V, Jezdimirović M, Borozan S, Savić M, Savić Đ. Downregulation of nicotinic and muscarinic receptor function in rats after subchronic exposure to diazinon. in Toxicology Reports. 2016;3:523-530.
doi:10.1016/j.toxrep.2016.06.002 .

Ivanović, Saša, Dimitrijević, Blagoje, Ćupić, Vitomir, Jezdimirović, Milanka, Borozan, Sunčica, Savić, Mila, Savić, Đorđe, "Downregulation of nicotinic and muscarinic receptor function in rats after subchronic exposure to diazinon" in Toxicology Reports, 3 (2016):523-530,
https://doi.org/10.1016/j.toxrep.2016.06.002 . .

TY  - JOUR
AU  - Kirovski, Danijela
AU  - Dodovski, Petar
AU  - Savić, Đorđe
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Mirilović, Milorad
AU  - Sladojević, Željko
AU  - Đorđević, Ana
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1366
AB  - The aim of our study was to investigate if the thyroid axis of newborn calves is affected by prenatal application of propylthyouracil (PTU). The study included 20 late pregnant Holstein cows. One group (n=10) was treated with PTU (4 mg/kg of BW daily) from day 20 before expected calving until the day of calving. The other group (n=10) was non-treated. Placental samples of dams were obtained for measuring mRNA expression of iodothyronine deiodinases type I (D1), type II (D2) and type III (D3). After parturition calves were separated from the dams and included in the study. Blood samples were taken daily from each calf starting on the day of birth until day 7 of age. Blood T3, T4 and TSH concentrations were measured. PCR analysis of the placental tissue revealed an abundance of all three types of placental deiodinases in non-treated cows, and a significant elevation of mRNA levels for all three types of deiodinases after PTU treatment. Calves that originated from dams treated with PTU had significantly lower T3 and T4 and significantly higher TSH concentrations compared to non-treated calves during the first 2 days of life. Starting from day 4 until day 6 of life the opposite effect was observed meaning that calves prenatally exposed to PTU had significantly higher T3 and T4 and slightly lower TSH. Our study, for the first time, provides information related to iodothyronine deiodinases mRNA expression in bovine placenta, and confirm that PTU treatment of pregnant dams provokes depression of thyroid function in newborns during the first days of life.
AB  - Cilj ovog rada bio je da se ispita da li je tireoidna osovina novorođene teladi promenjena nakon prenatalne aplikacije propiltiouracila (PTU). U ogled je uključeno 20 krava holštajn rase u kasnom graviditetu. Prva grupa (n=10) je tretirana PTU (4 mg/kg telesne mase, dnevna doza) počevši od 20 dana pre očekivanog teljenja do dana teljenja. Druga grupa (n=10) nije tretirana. Uzorci placente krava uzimani su u cilju određivanja ekspresije iRNK dejodinaza tipa I (D1), tipa II (D2) i tipa III (D3). Nakon teljenja, telad su odvojena od majki i uključena u ispitivanja. Uzorci krvi su uzimani dnevno od svakog teleta počevši od dana rođenja do 7. dana života. U krvi su merene koncentracije T3, T4 i TSH. PCR analiza tkiva placente je pokazala zastupljenost sva tri tipa dejodinaza kod netretiranih krava, i značajno povećanje nivoa iRNK sva tri tipa dejodinaza nakon tretmana PTU. Telad koja su poticala od majki tretiranih PTU imala su značajno niže koncentracije T3 i T4 i značajno više koncentracije TSH u odnosu na telad poreklom od netretiranih majki, tokom prva dva dana života. U periodu od 4. do 6. dana života, utvrđen je suprotan efekat, što znači da su telad prenatalno izložena delovanju PTU imala značajno više koncentracije T3 i T4 i značajno niže koncentracije TSH u odnosu na netretiranu telad. Naša studija, po prvi put, daje informacije vezane za ekspresiju dejodinaza u bovinoj placenti i potvrđuje da tretman gravidnih majki sa PTU izaziva depresiju funkcije tireoidne osovine kod novorođenčadi tokom prva dva dana neonatalnog života.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves
T1  - Ekspresija dejodinaza u placenti krava tretiranih sa propiltiouracilom (PTU) i aktivnost tireoidne osovine njihove teladi
VL  - 66
IS  - 1
SP  - 61
EP  - 75
DO  - 10.1515/acve-2016-0005
ER  - 

@article{
author = "Kirovski, Danijela and Dodovski, Petar and Savić, Đorđe and Vujanac, Ivan and Prodanović, Radiša and Mirilović, Milorad and Sladojević, Željko and Đorđević, Ana",
year = "2016",
abstract = "The aim of our study was to investigate if the thyroid axis of newborn calves is affected by prenatal application of propylthyouracil (PTU). The study included 20 late pregnant Holstein cows. One group (n=10) was treated with PTU (4 mg/kg of BW daily) from day 20 before expected calving until the day of calving. The other group (n=10) was non-treated. Placental samples of dams were obtained for measuring mRNA expression of iodothyronine deiodinases type I (D1), type II (D2) and type III (D3). After parturition calves were separated from the dams and included in the study. Blood samples were taken daily from each calf starting on the day of birth until day 7 of age. Blood T3, T4 and TSH concentrations were measured. PCR analysis of the placental tissue revealed an abundance of all three types of placental deiodinases in non-treated cows, and a significant elevation of mRNA levels for all three types of deiodinases after PTU treatment. Calves that originated from dams treated with PTU had significantly lower T3 and T4 and significantly higher TSH concentrations compared to non-treated calves during the first 2 days of life. Starting from day 4 until day 6 of life the opposite effect was observed meaning that calves prenatally exposed to PTU had significantly higher T3 and T4 and slightly lower TSH. Our study, for the first time, provides information related to iodothyronine deiodinases mRNA expression in bovine placenta, and confirm that PTU treatment of pregnant dams provokes depression of thyroid function in newborns during the first days of life., Cilj ovog rada bio je da se ispita da li je tireoidna osovina novorođene teladi promenjena nakon prenatalne aplikacije propiltiouracila (PTU). U ogled je uključeno 20 krava holštajn rase u kasnom graviditetu. Prva grupa (n=10) je tretirana PTU (4 mg/kg telesne mase, dnevna doza) počevši od 20 dana pre očekivanog teljenja do dana teljenja. Druga grupa (n=10) nije tretirana. Uzorci placente krava uzimani su u cilju određivanja ekspresije iRNK dejodinaza tipa I (D1), tipa II (D2) i tipa III (D3). Nakon teljenja, telad su odvojena od majki i uključena u ispitivanja. Uzorci krvi su uzimani dnevno od svakog teleta počevši od dana rođenja do 7. dana života. U krvi su merene koncentracije T3, T4 i TSH. PCR analiza tkiva placente je pokazala zastupljenost sva tri tipa dejodinaza kod netretiranih krava, i značajno povećanje nivoa iRNK sva tri tipa dejodinaza nakon tretmana PTU. Telad koja su poticala od majki tretiranih PTU imala su značajno niže koncentracije T3 i T4 i značajno više koncentracije TSH u odnosu na telad poreklom od netretiranih majki, tokom prva dva dana života. U periodu od 4. do 6. dana života, utvrđen je suprotan efekat, što znači da su telad prenatalno izložena delovanju PTU imala značajno više koncentracije T3 i T4 i značajno niže koncentracije TSH u odnosu na netretiranu telad. Naša studija, po prvi put, daje informacije vezane za ekspresiju dejodinaza u bovinoj placenti i potvrđuje da tretman gravidnih majki sa PTU izaziva depresiju funkcije tireoidne osovine kod novorođenčadi tokom prva dva dana neonatalnog života.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves, Ekspresija dejodinaza u placenti krava tretiranih sa propiltiouracilom (PTU) i aktivnost tireoidne osovine njihove teladi",
volume = "66",
number = "1",
pages = "61-75",
doi = "10.1515/acve-2016-0005"
}

Kirovski, D., Dodovski, P., Savić, Đ., Vujanac, I., Prodanović, R., Mirilović, M., Sladojević, Ž.,& Đorđević, A.. (2016). Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 66(1), 61-75.
https://doi.org/10.1515/acve-2016-0005

Kirovski D, Dodovski P, Savić Đ, Vujanac I, Prodanović R, Mirilović M, Sladojević Ž, Đorđević A. Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves. in Acta Veterinaria-Beograd. 2016;66(1):61-75.
doi:10.1515/acve-2016-0005 .

Kirovski, Danijela, Dodovski, Petar, Savić, Đorđe, Vujanac, Ivan, Prodanović, Radiša, Mirilović, Milorad, Sladojević, Željko, Đorđević, Ana, "Placental iodothyronine deiodinases expression in pregnant cows exposed to propylthiouracil (PTU) and thyroid axis activity of their calves" in Acta Veterinaria-Beograd, 66, no. 1 (2016):61-75,
https://doi.org/10.1515/acve-2016-0005 . .

TY  - JOUR
AU  - Savić, Mila
AU  - Baltić, Milan Ž.
AU  - Becskei, Zsolt
AU  - Dimitrijević, Blagoje
AU  - Dimitrijević, Vladimir
AU  - Savić, Đorđe
AU  - Vegara, Mensur
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1151
AB  - The objective of the study was to perform and evaluate the advanced phenotypic characterization of endangered Zackel sheep types, especially their productive potential and meat quality traits. Meat quality characteristics (m. longissimus dorsi) were evaluated in lambs of three types of autochthonous Zackel sheep: Sjenica sheep, Lipe sheep and Vlashko Vitoroga sheep, reared in traditional habitats in a sustainable management system. For the evaluation of sensory characteristics of lamb meat, quantitative descriptive analysis was performed according to ISO 6564:1985, i.e. structural intensity scale of seven points. All Zackel meat samples had an overall acceptability, the most favorable being in Sjenica sheep, with detected differences between Sjenica and Vlashko Vitoroga sheep (p lt 0.01), as well as between Lipe and Vlashko Vitoroga sheep (p lt 0.05). For the determination of fatty acids profile the prepared samples were analyzed using gas chromatography. The results showed that all tested lamb meat samples contain favorable amounts of conjugated linoleic acid (CLA). The average content of conjugated linoleic acid was higher in Sjenica lamb meat compared with Lipe lamb meat, and the difference was significant (p lt 0.01). It is also shown that examined samples of Sjenica, Lipe and Vlashko Vitoroga lambs, compared to many other exotic and local breeds, were characterized by preferable values of n-6:n-3 fatty acid ratio. Polyunsaturated fatty acid n-6:n-3 ratio difference between tested Zackel types was not significant. The favorable fatty acid profile, important for human health and especially for infant and children nutrition, raises the interest for sustainable production and conservation of Zackel sheep.
AB  - Predmet istraživanja je bio da se bliže ispitaju fenotipske osobine različitih ugroženih sojeva pramenke, a naročito potencijal za proizvodnju i kvalitet mesa. Karakteristike kvaliteta mesa (m. longissimus dorsi) su ispitivane kod tri soja autohtone rase pramenke, i to kod sjeničkog, lipskog i vlaško vitorogog soja, koji se gaje u tradicionalnim uslovima. Za kvantitativnu deskriptivnu analizu senzornih osobina mesa jagnjadi korišćene su strukturne skale intenziteta sa sedam tačaka (ISO 6564:1985). Svi uzorci mesa pramenke su imali visoku ocenu ukupne prihvatljivosti, najpovoljnije je ocenjen sjenički soj, uz utvrđenu razliku između sjeničkog i vlaško vitorogog soja (p lt 0,01), kao i između lipskog i vlaško vitorogog soja (p lt 0,05). Za određivanje sadržaja masnih kiselina uzorci su analizirani korišćenjem gasne hromatografi je. Rezultati su pokazali da svi ispitivani sojevi pramenke sadrže povoljan masnokiselinski sastav uz visok sadržaj konjugovane linoleinske kiseline (CLA). Utvrđen je veći prosečan sadržaj konjugovane linoleinske kiseline kod sjeničkog soja u odnosu na lipski soj (p lt 0,01). Takođe je utvrđeno da ispitivani uzorci sjeničkog, lipskog i vlaško vitorogog soja, poređeni sa drugim egzotičnim i lokalnim rasama, imaju bolji odnos n-6:n-3 polinezasićenih masnih kiselina, a statistička značajnost razlike između pojedinih sojeva pramenke nije utvrđena. Poželjan profi l masnih kiselina, značajan za zdravlje ljudi, a posebno za ishranu odojčadi i dece, podstiče interes za održivu proizvodnju i proces očuvanja ugroženih sojeva pramenke.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Evaluation of Zackel lamb meat quality with the aim of increasing the conservation value of the breed
T1  - Ispitivanje kvaliteta mesa jagnjadi pramenke u cilju povećanja vrednosti rase u procesu konzervacije
VL  - 64
IS  - 4
SP  - 438
EP  - 446
DO  - 10.2478/acve-2014-0041
ER  - 

@article{
author = "Savić, Mila and Baltić, Milan Ž. and Becskei, Zsolt and Dimitrijević, Blagoje and Dimitrijević, Vladimir and Savić, Đorđe and Vegara, Mensur",
year = "2014",
abstract = "The objective of the study was to perform and evaluate the advanced phenotypic characterization of endangered Zackel sheep types, especially their productive potential and meat quality traits. Meat quality characteristics (m. longissimus dorsi) were evaluated in lambs of three types of autochthonous Zackel sheep: Sjenica sheep, Lipe sheep and Vlashko Vitoroga sheep, reared in traditional habitats in a sustainable management system. For the evaluation of sensory characteristics of lamb meat, quantitative descriptive analysis was performed according to ISO 6564:1985, i.e. structural intensity scale of seven points. All Zackel meat samples had an overall acceptability, the most favorable being in Sjenica sheep, with detected differences between Sjenica and Vlashko Vitoroga sheep (p lt 0.01), as well as between Lipe and Vlashko Vitoroga sheep (p lt 0.05). For the determination of fatty acids profile the prepared samples were analyzed using gas chromatography. The results showed that all tested lamb meat samples contain favorable amounts of conjugated linoleic acid (CLA). The average content of conjugated linoleic acid was higher in Sjenica lamb meat compared with Lipe lamb meat, and the difference was significant (p lt 0.01). It is also shown that examined samples of Sjenica, Lipe and Vlashko Vitoroga lambs, compared to many other exotic and local breeds, were characterized by preferable values of n-6:n-3 fatty acid ratio. Polyunsaturated fatty acid n-6:n-3 ratio difference between tested Zackel types was not significant. The favorable fatty acid profile, important for human health and especially for infant and children nutrition, raises the interest for sustainable production and conservation of Zackel sheep., Predmet istraživanja je bio da se bliže ispitaju fenotipske osobine različitih ugroženih sojeva pramenke, a naročito potencijal za proizvodnju i kvalitet mesa. Karakteristike kvaliteta mesa (m. longissimus dorsi) su ispitivane kod tri soja autohtone rase pramenke, i to kod sjeničkog, lipskog i vlaško vitorogog soja, koji se gaje u tradicionalnim uslovima. Za kvantitativnu deskriptivnu analizu senzornih osobina mesa jagnjadi korišćene su strukturne skale intenziteta sa sedam tačaka (ISO 6564:1985). Svi uzorci mesa pramenke su imali visoku ocenu ukupne prihvatljivosti, najpovoljnije je ocenjen sjenički soj, uz utvrđenu razliku između sjeničkog i vlaško vitorogog soja (p lt 0,01), kao i između lipskog i vlaško vitorogog soja (p lt 0,05). Za određivanje sadržaja masnih kiselina uzorci su analizirani korišćenjem gasne hromatografi je. Rezultati su pokazali da svi ispitivani sojevi pramenke sadrže povoljan masnokiselinski sastav uz visok sadržaj konjugovane linoleinske kiseline (CLA). Utvrđen je veći prosečan sadržaj konjugovane linoleinske kiseline kod sjeničkog soja u odnosu na lipski soj (p lt 0,01). Takođe je utvrđeno da ispitivani uzorci sjeničkog, lipskog i vlaško vitorogog soja, poređeni sa drugim egzotičnim i lokalnim rasama, imaju bolji odnos n-6:n-3 polinezasićenih masnih kiselina, a statistička značajnost razlike između pojedinih sojeva pramenke nije utvrđena. Poželjan profi l masnih kiselina, značajan za zdravlje ljudi, a posebno za ishranu odojčadi i dece, podstiče interes za održivu proizvodnju i proces očuvanja ugroženih sojeva pramenke.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Evaluation of Zackel lamb meat quality with the aim of increasing the conservation value of the breed, Ispitivanje kvaliteta mesa jagnjadi pramenke u cilju povećanja vrednosti rase u procesu konzervacije",
volume = "64",
number = "4",
pages = "438-446",
doi = "10.2478/acve-2014-0041"
}

Savić, M., Baltić, M. Ž., Becskei, Z., Dimitrijević, B., Dimitrijević, V., Savić, Đ.,& Vegara, M.. (2014). Evaluation of Zackel lamb meat quality with the aim of increasing the conservation value of the breed. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 64(4), 438-446.
https://doi.org/10.2478/acve-2014-0041

Savić M, Baltić MŽ, Becskei Z, Dimitrijević B, Dimitrijević V, Savić Đ, Vegara M. Evaluation of Zackel lamb meat quality with the aim of increasing the conservation value of the breed. in Acta Veterinaria-Beograd. 2014;64(4):438-446.
doi:10.2478/acve-2014-0041 .

Savić, Mila, Baltić, Milan Ž., Becskei, Zsolt, Dimitrijević, Blagoje, Dimitrijević, Vladimir, Savić, Đorđe, Vegara, Mensur, "Evaluation of Zackel lamb meat quality with the aim of increasing the conservation value of the breed" in Acta Veterinaria-Beograd, 64, no. 4 (2014):438-446,
https://doi.org/10.2478/acve-2014-0041 . .

TY  - JOUR
AU  - Kirovski, Danijela
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Đurić, Miloje
AU  - Sladojević, Željko
AU  - Savić, Đorđe
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1127
AB  - The objective of this work was to compare the composition of colostrum and milk of cows and sows (content of dry matter, protein, milk fat and lactose, concentration of IGF-I and insulin) in samples taken on the first, second, third and seventh day after parturition, and then based on the differences in composition to determine a biological significance of nutrition of newborn during the earliest stages of their life. The investigation included 14 cows of Holstein breed and 14 sows of Landrace breed. The content of dry matter and the concentration of proteins in both colostrum and milk samples were statistically significantly higher in regard to sows mammary glands secretion, taken on the first day after the parturition (p lt 0,01 and p lt 0,001, individually), but their decrease in mammary glands secretion was more pronounced in the cows than the sows, during the first seven days. The concentration IGF-I was statistically significantly higher in the cows colostrum and milk in regard to the sows during the whole investigation period, while the concentration of insulin was significantly higher in the sows in regard to the cows during the same period. The concentrations of milk fat and lactose in cows milk samples were significantly lower in regard to the sows in all period of the study. On the basis of the obtained results, it can be concluded that there are significant differences in the composition of milk and colostrum of both the investigated animal species. The differences are probably the result of evolutionary adaptation of mammal gland function to nutrition, energy and protection requirements of these young animals in their early postnatal life.
AB  - Cilj rada bio je da se uporedi sastav kolostruma i mleka krava i krmača (sadržaj suve materije, proteina, mlečne masti i laktoze, koncentracija IGF-I i insulina) u uzorcima uzetim prvog, drugog, trećeg i sedmog dana nakon porođaja i na osnovu razlika u sastavu ustanovi biološki značaj u ishrani njihovog podmlatka u najranijoj fazi života. U ispitivanje je uključeno 14 krava holštajn rase i 14 krmača rase landras. Procenat suve materije i koncentracija proteina u uzorcima kolostruma i mleka krava bili su statistički značajno viši u odnosu na sekret mlečne žlezde krmače u uzorcima uzetim prvog dana nakon porođaja (p lt 0,01 i p lt 0,001, pojedinačno) ali je smanjenje njihovog sadržaja u sekretu mlečne žlezde tokom prvih sedam dana bilo izraženije kod krava u odnosu na krmače. Koncentracija IGF-I bila je statistički značajno viša u kolostrumu i mleku krava u odnosu na krmače tokom celog perioda ispitivanja, dok je koncentracija insulina bila značajno viša kod krmača u odnosu na krave tokom istog perioda. Koncentracije mlečne masti i laktoze u uzorcima mleka krava bile su značajno niže u odnosu na krmače u svim periodima ispitivanja. Na osnovu dobijenih rezultata može se zaključiti da postoje značajne razlike u sastavu kolostruma i mleka kod dve ispitivane vrste životinja. Te razlike su najverovatnije posledica evolutivnog prilagođavanja funkcije mlečne žlezde nutritivnim, energetskim i zaštitnim potrebama mladunčadi ovih vrsta životinja u panom postnatalnom životu.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - The biological significance of differences in cows and sows colostrum and milk composition
T1  - Biologičeskoe značenie različij v sostave kolostruma i moloka korov i svinomatok
T1  - Biološki značaj razlika u sastavu kolostruma i mleka krava i krmača
VL  - 68
IS  - 3-4
SP  - 175
EP  - 188
DO  - 10.2298/VETGL1404175K
ER  - 

@article{
author = "Kirovski, Danijela and Vujanac, Ivan and Prodanović, Radiša and Đurić, Miloje and Sladojević, Željko and Savić, Đorđe",
year = "2014",
abstract = "The objective of this work was to compare the composition of colostrum and milk of cows and sows (content of dry matter, protein, milk fat and lactose, concentration of IGF-I and insulin) in samples taken on the first, second, third and seventh day after parturition, and then based on the differences in composition to determine a biological significance of nutrition of newborn during the earliest stages of their life. The investigation included 14 cows of Holstein breed and 14 sows of Landrace breed. The content of dry matter and the concentration of proteins in both colostrum and milk samples were statistically significantly higher in regard to sows mammary glands secretion, taken on the first day after the parturition (p lt 0,01 and p lt 0,001, individually), but their decrease in mammary glands secretion was more pronounced in the cows than the sows, during the first seven days. The concentration IGF-I was statistically significantly higher in the cows colostrum and milk in regard to the sows during the whole investigation period, while the concentration of insulin was significantly higher in the sows in regard to the cows during the same period. The concentrations of milk fat and lactose in cows milk samples were significantly lower in regard to the sows in all period of the study. On the basis of the obtained results, it can be concluded that there are significant differences in the composition of milk and colostrum of both the investigated animal species. The differences are probably the result of evolutionary adaptation of mammal gland function to nutrition, energy and protection requirements of these young animals in their early postnatal life., Cilj rada bio je da se uporedi sastav kolostruma i mleka krava i krmača (sadržaj suve materije, proteina, mlečne masti i laktoze, koncentracija IGF-I i insulina) u uzorcima uzetim prvog, drugog, trećeg i sedmog dana nakon porođaja i na osnovu razlika u sastavu ustanovi biološki značaj u ishrani njihovog podmlatka u najranijoj fazi života. U ispitivanje je uključeno 14 krava holštajn rase i 14 krmača rase landras. Procenat suve materije i koncentracija proteina u uzorcima kolostruma i mleka krava bili su statistički značajno viši u odnosu na sekret mlečne žlezde krmače u uzorcima uzetim prvog dana nakon porođaja (p lt 0,01 i p lt 0,001, pojedinačno) ali je smanjenje njihovog sadržaja u sekretu mlečne žlezde tokom prvih sedam dana bilo izraženije kod krava u odnosu na krmače. Koncentracija IGF-I bila je statistički značajno viša u kolostrumu i mleku krava u odnosu na krmače tokom celog perioda ispitivanja, dok je koncentracija insulina bila značajno viša kod krmača u odnosu na krave tokom istog perioda. Koncentracije mlečne masti i laktoze u uzorcima mleka krava bile su značajno niže u odnosu na krmače u svim periodima ispitivanja. Na osnovu dobijenih rezultata može se zaključiti da postoje značajne razlike u sastavu kolostruma i mleka kod dve ispitivane vrste životinja. Te razlike su najverovatnije posledica evolutivnog prilagođavanja funkcije mlečne žlezde nutritivnim, energetskim i zaštitnim potrebama mladunčadi ovih vrsta životinja u panom postnatalnom životu.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "The biological significance of differences in cows and sows colostrum and milk composition, Biologičeskoe značenie različij v sostave kolostruma i moloka korov i svinomatok, Biološki značaj razlika u sastavu kolostruma i mleka krava i krmača",
volume = "68",
number = "3-4",
pages = "175-188",
doi = "10.2298/VETGL1404175K"
}

Kirovski, D., Vujanac, I., Prodanović, R., Đurić, M., Sladojević, Ž.,& Savić, Đ.. (2014). The biological significance of differences in cows and sows colostrum and milk composition. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 68(3-4), 175-188.
https://doi.org/10.2298/VETGL1404175K

Kirovski D, Vujanac I, Prodanović R, Đurić M, Sladojević Ž, Savić Đ. The biological significance of differences in cows and sows colostrum and milk composition. in Veterinarski Glasnik. 2014;68(3-4):175-188.
doi:10.2298/VETGL1404175K .

Kirovski, Danijela, Vujanac, Ivan, Prodanović, Radiša, Đurić, Miloje, Sladojević, Željko, Savić, Đorđe, "The biological significance of differences in cows and sows colostrum and milk composition" in Veterinarski Glasnik, 68, no. 3-4 (2014):175-188,
https://doi.org/10.2298/VETGL1404175K . .

TY  - JOUR
AU  - Šamanc, Horea
AU  - Kirovski, Danijela
AU  - Savić, Đorđe
AU  - Sladojević, Željko
AU  - Vujanac, Ivan
AU  - Zarcula, Simona
PY  - 2009
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/588
AB  - Abomasal displacement is one of the most important disorders of the digestive tract in high-yield dairy cows. The etiology and pathogenesis of its occurrence has not been fully clarified to this day. The work examines calcaemia and phosphataemia in cows during the antepartal and postpartal periods and their connection with the incidence of abomasal displacement. The experiment covered 30 cows in advanced stages of gravidity. Blood samples were taken two weeks before expected parturition and two weeks after calving. In all blood samples (taken antepartal and postpartal), concentrations of calcium and an organic phosphorus were determined using a commercial test package (Bio-Merieux). Following parturition, left displacement of the abomasums was established in seven (23.33 %) of the 30 cows covered by the experiment (experimental group). The remaining 23 cows in the experiment were clinically healthy, they were placed in a group and represented control animals. The average value of calcaemia for the control group of cows during the antepartal period was 2.72±0.25 mmol/l, and of phosphataemia 2.04±0.25 mmol/l. In the same cows postpartum, average calcaemia values were 2.46±0.22 mmol/l and phosphataemia 1.85±0.29 mmol/l. The average antepartal value for calcaemia in the experimental group of cows was 2.51±0.25 mmol/l, and for phosphataemia 1.73± 0.22 mmol/l. The average values for this group of cows postpartally was 2.13±0.31 mmol/l for calcaemia and 1.43±0.24 mmol/l for phosphataemia. The differences between the concentration values for calcium and phosphorus obtained postpartally between the experimental and control groups were statistically significant. .
AB  - Promena položaja sirišta je jedno od najznačajnijih oboljenja organa za varenje kod visoko-mlečnih krava. Etiologija i patogeneza njegovog nastanka ni do danas nije u potpunosti objašnjena. U radu je ispitana kalcemija i fosfatemija kod krava u antepartalnom i postpartalnom periodu i njena povezanost sa pojavom promene položaja sirišta. U ogled je bilo uključeno 30 krava u visokom graviditetu. Uzorci krvi uzeti su dve nedelje pre očekivanog partusa, kao i dve nedelje nakon teljenja. U svim uzorcima krvnog seruma (uzetim antepartalno i postpartalno) određivana je koncentracija kalcijuma i anorganskog fosfora, korišćenjem komercijalnih test paketa (Bio-Merieux). Kod 7 krava od 30 uključenih u ogled (23,33%) nakon teljenja je kliničkim pregledom ustanovljena promena položaja sirišta na levo (eksperimentalna grupa). Preostale 23 krave iz ogleda su bile klinički zdrave i predstavljale su kontrolnu grupu. Prosečna vrednost kalcemije kontrolne grupe krava u antepartalnom periodu iznosila je 2,72±0,25 mmol/l, a fosfatemije 2,04±0,25 mmol/l. Kod ovih krava je postpartalno ustanovljena prosečna vrednost kalcemije od 2,46±0,22 mmol/l i fosfatemije od 1,85±0,29 mmol/l. Prosečna antepartalna vrednost kalcemije eksperimentalne grupe krava iznosila je 2,51±0,25 mmol/l, a fosfatemije 1,73±0,22 mmol/l. Postpartalno su prosečne vrednosti kalcemije i fosfatemije ove grupe krava iznosile 2,13±0,31 mmol/l i 1,43± 0,24 mmol/l. Razlike između vrednosti za koncentraciju kalcijuma i fosfora dobijene postpartalno između eksperimentalne i kontrolne grupe su bile statistički značajne.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Blood calcium and phosphorus concentrations in cows with left displaced abomasum
T1  - Koncentracija kalcijuma i fosfora u krvnom serumu krava sa dislokacijom sirišta na levo
VL  - 63
IS  - 5-6
SP  - 331
EP  - 340
DO  - 10.2298/VETGL0906331S
ER  - 

@article{
author = "Šamanc, Horea and Kirovski, Danijela and Savić, Đorđe and Sladojević, Željko and Vujanac, Ivan and Zarcula, Simona",
year = "2009",
abstract = "Abomasal displacement is one of the most important disorders of the digestive tract in high-yield dairy cows. The etiology and pathogenesis of its occurrence has not been fully clarified to this day. The work examines calcaemia and phosphataemia in cows during the antepartal and postpartal periods and their connection with the incidence of abomasal displacement. The experiment covered 30 cows in advanced stages of gravidity. Blood samples were taken two weeks before expected parturition and two weeks after calving. In all blood samples (taken antepartal and postpartal), concentrations of calcium and an organic phosphorus were determined using a commercial test package (Bio-Merieux). Following parturition, left displacement of the abomasums was established in seven (23.33 %) of the 30 cows covered by the experiment (experimental group). The remaining 23 cows in the experiment were clinically healthy, they were placed in a group and represented control animals. The average value of calcaemia for the control group of cows during the antepartal period was 2.72±0.25 mmol/l, and of phosphataemia 2.04±0.25 mmol/l. In the same cows postpartum, average calcaemia values were 2.46±0.22 mmol/l and phosphataemia 1.85±0.29 mmol/l. The average antepartal value for calcaemia in the experimental group of cows was 2.51±0.25 mmol/l, and for phosphataemia 1.73± 0.22 mmol/l. The average values for this group of cows postpartally was 2.13±0.31 mmol/l for calcaemia and 1.43±0.24 mmol/l for phosphataemia. The differences between the concentration values for calcium and phosphorus obtained postpartally between the experimental and control groups were statistically significant. ., Promena položaja sirišta je jedno od najznačajnijih oboljenja organa za varenje kod visoko-mlečnih krava. Etiologija i patogeneza njegovog nastanka ni do danas nije u potpunosti objašnjena. U radu je ispitana kalcemija i fosfatemija kod krava u antepartalnom i postpartalnom periodu i njena povezanost sa pojavom promene položaja sirišta. U ogled je bilo uključeno 30 krava u visokom graviditetu. Uzorci krvi uzeti su dve nedelje pre očekivanog partusa, kao i dve nedelje nakon teljenja. U svim uzorcima krvnog seruma (uzetim antepartalno i postpartalno) određivana je koncentracija kalcijuma i anorganskog fosfora, korišćenjem komercijalnih test paketa (Bio-Merieux). Kod 7 krava od 30 uključenih u ogled (23,33%) nakon teljenja je kliničkim pregledom ustanovljena promena položaja sirišta na levo (eksperimentalna grupa). Preostale 23 krave iz ogleda su bile klinički zdrave i predstavljale su kontrolnu grupu. Prosečna vrednost kalcemije kontrolne grupe krava u antepartalnom periodu iznosila je 2,72±0,25 mmol/l, a fosfatemije 2,04±0,25 mmol/l. Kod ovih krava je postpartalno ustanovljena prosečna vrednost kalcemije od 2,46±0,22 mmol/l i fosfatemije od 1,85±0,29 mmol/l. Prosečna antepartalna vrednost kalcemije eksperimentalne grupe krava iznosila je 2,51±0,25 mmol/l, a fosfatemije 1,73±0,22 mmol/l. Postpartalno su prosečne vrednosti kalcemije i fosfatemije ove grupe krava iznosile 2,13±0,31 mmol/l i 1,43± 0,24 mmol/l. Razlike između vrednosti za koncentraciju kalcijuma i fosfora dobijene postpartalno između eksperimentalne i kontrolne grupe su bile statistički značajne.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Blood calcium and phosphorus concentrations in cows with left displaced abomasum, Koncentracija kalcijuma i fosfora u krvnom serumu krava sa dislokacijom sirišta na levo",
volume = "63",
number = "5-6",
pages = "331-340",
doi = "10.2298/VETGL0906331S"
}

Šamanc, H., Kirovski, D., Savić, Đ., Sladojević, Ž., Vujanac, I.,& Zarcula, S.. (2009). Blood calcium and phosphorus concentrations in cows with left displaced abomasum. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 63(5-6), 331-340.
https://doi.org/10.2298/VETGL0906331S

Šamanc H, Kirovski D, Savić Đ, Sladojević Ž, Vujanac I, Zarcula S. Blood calcium and phosphorus concentrations in cows with left displaced abomasum. in Veterinarski Glasnik. 2009;63(5-6):331-340.
doi:10.2298/VETGL0906331S .

Šamanc, Horea, Kirovski, Danijela, Savić, Đorđe, Sladojević, Željko, Vujanac, Ivan, Zarcula, Simona, "Blood calcium and phosphorus concentrations in cows with left displaced abomasum" in Veterinarski Glasnik, 63, no. 5-6 (2009):331-340,
https://doi.org/10.2298/VETGL0906331S . .