TY  - JOUR
AU  - Marques, Catia
AU  - Gama, Luis Telo
AU  - Belas, Adriana
AU  - Bergstrom, Karin
AU  - Beurlet, Stephanie
AU  - Briend-Marchal, Alexandra
AU  - Broens, Els M.
AU  - Costa, Marta
AU  - Criel, Delphine
AU  - Damborg, Peter
AU  - van Dijk, Marloes A. M.
AU  - van Dongen, Astrid M.
AU  - Dorsch, Roswitha
AU  - Espada, Carmen Martin
AU  - Gerber, Bernhard
AU  - Kritsepi-Konstantinou, Maria
AU  - Loncarić, Igor
AU  - Mion, Domenico
AU  - Mišić, Dušan
AU  - Movilla, Rebeca
AU  - Overesch, Gudrun
AU  - Perreten, Vincent
AU  - Roura, Xavier
AU  - Steenbergen, Joachim
AU  - Timofte, Dorina
AU  - Wolf, Georg
AU  - Zanoni, Renato Giulio
AU  - Schmitt, Sarah
AU  - Guardabassi, Luca
AU  - Pomba, Constanca
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1389
AB  - Background: There is a growing concern regarding the increase of antimicrobial resistant bacteria in companion animals. Yet, there are no studies comparing the resistance levels of these organisms in European countries. The aim of this study was to investigate geographical and temporal trends of antimicrobial resistant bacteria causing urinary tract infection (UTI) in companion animals in Europe. The antimicrobial susceptibility of 22 256 bacteria isolated from dogs and cats with UTI was determined. Samples were collected between 2008 and 2013 from 16 laboratories of 14 European countries. The prevalence of antimicrobial resistance of the most common bacteria was determined for each country individually in the years 2012-2013 and temporal trends of bacteria resistance were established by logistic regression. Results: The aetiology of uropathogenic bacteria differed between dogs and cats. For all bacterial species, Southern countries generally presented higher levels of antimicrobial resistance compared to Northern countries. Multidrug-resistant Escherichia coli were found to be more prevalent in Southern countries. During the study period, the level of fluoroquinolone-resistant E. coli isolated in Belgium, Denmark, France and the Netherlands decreased significantly. A temporal increase in resistance to amoxicillin-clavulanate and gentamicin was observed among E. coli isolates from the Netherlands and Switzerland, respectively. Other country-specific temporal increases were observed for fluoroquinolone-resistant Proteus spp. isolated from companion animals from Belgium. Conclusions: This work brings new insights into the current status of antimicrobial resistance in bacteria isolated from companion animals with UTI in Europe and reinforces the need for strategies aiming to reduce resistance.
PB  - BMC, London
T2  - BMC Veterinary Research
T1  - European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections
VL  - 12
SP  - 213
DO  - 10.1186/s12917-016-0840-3
ER  - 

@article{
author = "Marques, Catia and Gama, Luis Telo and Belas, Adriana and Bergstrom, Karin and Beurlet, Stephanie and Briend-Marchal, Alexandra and Broens, Els M. and Costa, Marta and Criel, Delphine and Damborg, Peter and van Dijk, Marloes A. M. and van Dongen, Astrid M. and Dorsch, Roswitha and Espada, Carmen Martin and Gerber, Bernhard and Kritsepi-Konstantinou, Maria and Loncarić, Igor and Mion, Domenico and Mišić, Dušan and Movilla, Rebeca and Overesch, Gudrun and Perreten, Vincent and Roura, Xavier and Steenbergen, Joachim and Timofte, Dorina and Wolf, Georg and Zanoni, Renato Giulio and Schmitt, Sarah and Guardabassi, Luca and Pomba, Constanca",
year = "2016",
abstract = "Background: There is a growing concern regarding the increase of antimicrobial resistant bacteria in companion animals. Yet, there are no studies comparing the resistance levels of these organisms in European countries. The aim of this study was to investigate geographical and temporal trends of antimicrobial resistant bacteria causing urinary tract infection (UTI) in companion animals in Europe. The antimicrobial susceptibility of 22 256 bacteria isolated from dogs and cats with UTI was determined. Samples were collected between 2008 and 2013 from 16 laboratories of 14 European countries. The prevalence of antimicrobial resistance of the most common bacteria was determined for each country individually in the years 2012-2013 and temporal trends of bacteria resistance were established by logistic regression. Results: The aetiology of uropathogenic bacteria differed between dogs and cats. For all bacterial species, Southern countries generally presented higher levels of antimicrobial resistance compared to Northern countries. Multidrug-resistant Escherichia coli were found to be more prevalent in Southern countries. During the study period, the level of fluoroquinolone-resistant E. coli isolated in Belgium, Denmark, France and the Netherlands decreased significantly. A temporal increase in resistance to amoxicillin-clavulanate and gentamicin was observed among E. coli isolates from the Netherlands and Switzerland, respectively. Other country-specific temporal increases were observed for fluoroquinolone-resistant Proteus spp. isolated from companion animals from Belgium. Conclusions: This work brings new insights into the current status of antimicrobial resistance in bacteria isolated from companion animals with UTI in Europe and reinforces the need for strategies aiming to reduce resistance.",
publisher = "BMC, London",
journal = "BMC Veterinary Research",
title = "European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections",
volume = "12",
pages = "213",
doi = "10.1186/s12917-016-0840-3"
}

Marques, C., Gama, L. T., Belas, A., Bergstrom, K., Beurlet, S., Briend-Marchal, A., Broens, E. M., Costa, M., Criel, D., Damborg, P., van Dijk, M. A. M., van Dongen, A. M., Dorsch, R., Espada, C. M., Gerber, B., Kritsepi-Konstantinou, M., Loncarić, I., Mion, D., Mišić, D., Movilla, R., Overesch, G., Perreten, V., Roura, X., Steenbergen, J., Timofte, D., Wolf, G., Zanoni, R. G., Schmitt, S., Guardabassi, L.,& Pomba, C.. (2016). European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections. in BMC Veterinary Research
BMC, London., 12, 213.
https://doi.org/10.1186/s12917-016-0840-3

Marques C, Gama LT, Belas A, Bergstrom K, Beurlet S, Briend-Marchal A, Broens EM, Costa M, Criel D, Damborg P, van Dijk MAM, van Dongen AM, Dorsch R, Espada CM, Gerber B, Kritsepi-Konstantinou M, Loncarić I, Mion D, Mišić D, Movilla R, Overesch G, Perreten V, Roura X, Steenbergen J, Timofte D, Wolf G, Zanoni RG, Schmitt S, Guardabassi L, Pomba C. European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections. in BMC Veterinary Research. 2016;12:213.
doi:10.1186/s12917-016-0840-3 .

Marques, Catia, Gama, Luis Telo, Belas, Adriana, Bergstrom, Karin, Beurlet, Stephanie, Briend-Marchal, Alexandra, Broens, Els M., Costa, Marta, Criel, Delphine, Damborg, Peter, van Dijk, Marloes A. M., van Dongen, Astrid M., Dorsch, Roswitha, Espada, Carmen Martin, Gerber, Bernhard, Kritsepi-Konstantinou, Maria, Loncarić, Igor, Mion, Domenico, Mišić, Dušan, Movilla, Rebeca, Overesch, Gudrun, Perreten, Vincent, Roura, Xavier, Steenbergen, Joachim, Timofte, Dorina, Wolf, Georg, Zanoni, Renato Giulio, Schmitt, Sarah, Guardabassi, Luca, Pomba, Constanca, "European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections" in BMC Veterinary Research, 12 (2016):213,
https://doi.org/10.1186/s12917-016-0840-3 . .