dc.creator | Gavrilović, Milan | |
dc.creator | Tešević, Vele | |
dc.creator | Đorđević, Iris | |
dc.creator | Rajcević, Nemanja | |
dc.creator | Bakhia, Arsena | |
dc.creator | Garcia Jacas, Nuria | |
dc.creator | Susanna, Alfonso | |
dc.creator | Marin, Petar D. | |
dc.creator | Janaćković, Peđa | |
dc.date.accessioned | 2020-06-03T14:21:47Z | |
dc.date.available | 2020-06-03T14:21:47Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 0354-4664 | |
dc.identifier.uri | https://vet-erinar.vet.bg.ac.rs/handle/123456789/1575 | |
dc.description.abstract | We examined for the first time the leaf micromorphology, phytochemistry and biological activity of the rare and stenoendemic Amphoricarpos elegans Albov (Compositae) from Georgia. Scanning electron microscopy (SEM) revealed the presence of glandular trichomes on the leaves, which appeared as glandular dots that are considered the main sites of biosynthesis and accumulation of sesquiterpene lactones. Using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy analyses, we identify and characterized 3-deoxyamphoricarpolide, a known sesquiterpene lactone for the genus Amphoricarpos Vis. Regarding chemotaxonomic significance, 3-deoxyamphoricarpolide represents a link between Balkan and Caucasian species of the genus. The antioxidative capacity of different leaf extracts, obtained using a Soxhlet extractor, was evaluated by two radical scavenging assays: DPPH 91,1-diphenyl-2-picrylhydrazyl) radical and the 2,2-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS), and ferric ion reducing antioxidant power (FRAP). The total phenolic and flavonoid contents were also determined. The highest antioxidative activity and the highest phenolic and flavonoid contents were detected in the methanol fraction, as a result of the contribution of not only phenols, but probably also lactones. The considerable antioxidative potential indicates possible applications in pharmacy and medicine. | en |
dc.publisher | Srpsko biološko društvo, Beograd | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173029/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS// | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Archives of Biological Sciences | |
dc.subject | Amphoricarpos elegans | en |
dc.subject | glandular trichomes | en |
dc.subject | 3-deoxyamphoricarpolide | en |
dc.subject | antioxidative activity | en |
dc.title | Leaf micromorphology, antioxidative activity and a new record of 3-deoxyamphoricarpolide of relict and limestone endemic Amphoricarpos elegans Albov (Compositae) from Georgia | en |
dc.type | article | |
dc.rights.license | BY-NC-ND | |
dcterms.abstract | Ђорђевић, Ирис; Тешевић, Веле; Јанаћковић, Пеђа; Бакхиа, Aрсена; Рајцевић, Немања; Гавриловић, Милан; Марин, Петар Д.; Гарциа Јацас, Нуриа; Сусанна, Aлфонсо; | |
dc.citation.volume | 70 | |
dc.citation.issue | 4 | |
dc.citation.spage | 613 | |
dc.citation.epage | 620 | |
dc.citation.other | 70(4): 613-620 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000452187000002 | |
dc.identifier.doi | 10.2298/ABS180309022G | |
dc.identifier.scopus | 2-s2.0-85058801815 | |
dc.identifier.fulltext | https://vet-erinar.vet.bg.ac.rs/bitstream/id/539/1574.pdf | |
dc.type.version | publishedVersion | |