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Antibacterial activity of griseofulvin analogues as an example of drug repurposing
(Elsevier, 2020)
Griseofulvin is a well-known antifungal drug that was launched in 1962 by Merck & Co. for the treatment of dermatophyte infections. However, according to predictions using the Way2Drug computational drug repurposing platform, ...
Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus
(Elsevier, Amsterdam, 2020)
Metabolomics generate a profile of small molecules from plant extracts, which could be directly responsible for bioactivity effects. Using thy-column flash chromatography enabled a rapid and inexpensive method for the very ...
Setting a baseline for global urban virome surveillance in sewage
(Springer Nature, 2020)
The rapid development of megacities, and their growing connectedness across the world is becoming a distinct driver for emerging disease outbreaks. Early detection of unusual disease emergence and spread should therefore ...
Molecular detection and characterization of Porcine Kobuvirus in domestic pigs and wild boars in Serbia
(Elsevier, 2020)
Porcine Kobuvirus (PKV) infection is very common in pigs throughout the world. Since it has never been investigated in Serbia, to contribute to the knowledge of Porcine Kobuvirus, its role, and distribution, we tested 200 ...
DNA-binding and DNA-protecting activities of small natural organic molecules and food extracts
(Elsevier Ireland Ltd, Clare, 2020)
The review summarizes literature data on the DNA-binding, DNA-protecting and DNA-damaging activities of a range of natural human endogenous and exogenous compounds. Small natural organic molecules bind DNA in a site-specific ...
Immunohistomorphometric and Hormonal Analysis of the Pituitary Gonadotropic Cells after Application of the Nandrolone Decanoate and Swimming Training in Adult Male Rats
(Cambridge University Press, 2020)
The aim of the study was to investigate the effects of chronic nandrolone decanoate treatment and/or swimming training on immunohistomorphometric parameters on rat pituitary gonadotropic cells. Male Wistar albino rats, 10 ...
Twenty-five-year study of Nosema spp. in honey bees (Apis mellifera) in Serbia
(Elsevier, Amsterdam, 2020)
A total of 7386 samples of adult honey bees from different areas of Serbia (fifteen regions and 79 municipalities) were selected for light microscopy analysis for Nosema species during 1992-2017. A selection of honey bee ...
Broad-spectrum cephalosporin-resistant and/or fluoroquinolone-resistant enterobacterales associated with canine and feline urogenital infections
(MDPI, 2020)
The aim of the present study was to characterize Enterobacterales resistant to 3rd and 4th generation cephalosporins, carbapenems and/or fluoroquinolones, isolated from dogs and cats with urogenital infections. In total, ...
Carvacrol acts as a potent selective antagonist of different types of nicotinic acetylcholine receptors and enhances the effect of monepantel in the parasitic nematode Ascaris suum
(Elsevier, Amsterdam, 2020)
The neuromuscular system of parasitic nematodes has proven to be an efficient pharmacological target for antihelmintics. Some of the most frequently used antiparasitic drugs are agonists or antagonists of nicotinic ...
Antidotal potency of the novel, structurally different adsorbents in rats acutely intoxicated with the T-2 toxin
(MDPI, 2020)
In this paper, the potential antidote efficacy of commercially available formulations of various feed additives such as Minazel-Plus®, Mycosorb®, and Mycofix® was considered by recording their incidence on general health, ...